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    Anderson County, SC Office Spaces for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    46 results
    Adaptable Commercial Property on Highway
    $925,000
    8,700 SF
    Adaptable Commercial Property on Highway

    6114 HWY 76, Pendleton, SC 29670

    Warehouse and office buildings with high traffic frontage on Highway.
    • High‑traffic location on HWY 76 with 15k‑22k vehicles per day
    • 7200+\/- sqft warehouse with 14x14 garage door and framed office/restroom/storage spaces
    • 1500+\/- sqft office building with 4 offices, conference room, waiting room, and 2 restrooms (1 handicap accessible)
    • Convenient access to I‑85 (less than 4 miles) and central location to Anderson, Clemson, and Pendleton
    • Two access points: HWY 76 and Circle St
    Updated: May 22
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    Commercial Property Near Downtown Anderson
    $429,000
    0.64 Acres
    Commercial Property Near Downtown Anderson

    3499 East River Street, Anderson, SC 29621

    Well-maintained flex building with office and warehouse space.
    • Well‑maintained commercial property with great curb appeal.
    • Approximately 2430 square feet of total space.
    • Includes 1150 square feet of finished office space with a large lobby and 3 offices.
    • Features 1280 square feet of unfinished warehouse space.
    • Equipped with a 9' roll‑up bay door.
    Updated: Apr 10
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    Williamston Commercial Opportunity For Sale
    $279,900
    1,850 SF
    Williamston Commercial Opportunity For Sale

    Commercial building with rental potential in Williamston, South Carolina.

    203 N Hamilton Street, Williamston, SC 29697

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    Belton Commercial Building on Two Acres
    $595,000
    5,000 SF
    Belton Commercial Building on Two Acres

    5,000 SF commercial building with office and warehouse space.

    3361 Highway 29 N, Belton, SC 29697

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    Versatile Office Building with Parking
    $290,000
    0.45 Acres
    Versatile Office Building with Parking

    Functional office building with ample parking in Belton, SC.

    713 Anderson Street, Belton, SC 29627

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    Warehouse & Flex Space Facility
    $425,000
    3.11 Acres
    Warehouse & Flex Space Facility

    Clear-span warehouse with flex-style potential, roll-up loading, and commercial/industrial zoning for a range of operations.

    109 Waybrook Drive, Anderson, SC 29624

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    Prime Commercial Land I-85 Frontage
    $949,000
    1.80 Acres
    Prime Commercial Land I-85 Frontage

    High-traffic commercial land with I-85 frontage in Anderson, SC.

    105 Destination Boulevard, Anderson, SC 29621

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    Belton Commercial Property on Main
    $185,000
    0.29 Acres
    Belton Commercial Property on Main

    Prime commercial property in downtown Belton, South Carolina.

    121 N Main Street, Belton, SC 29627

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    Prime Anderson Business Location
    $499,000
    0.25 Acres
    Prime Anderson Business Location

    Excellent visibility, move-in ready office space with parking.

    2006 N Main Street, Anderson, SC 29621

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    Office Building with Multiple Entrances
    $499,000
    0.25 Acres
    Office Building with Multiple Entrances

    Move-in-ready office property with paved front and rear parking, a heated/cooled sunroom, and flexible room layout.

    2006 N Main Street, Anderson, SC 29621

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    Williamston Commercial Building For Sale
    $279,900
    1,860 SF
    Williamston Commercial Building For Sale

    Commercial building in Williamston, SC with investment and rental potential.

    203 N Hamilton Street, Williamston, SC 29697

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    Versatile Property Near AnMed Hospital
    $925,000
    4,300 SF
    Versatile Property Near AnMed Hospital

    Versatile 4,300 SF property suitable for office or retail.

    1502 E Greenville St, Anderson, SC 29621

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    Buildable Medical Office Pad Site
    $90,000
    0.48 Acres
    Buildable Medical Office Pad Site

    Condo-style pad site in established medical park setting.

    110 Buford Avenue lot: 28B, Anderson, SC 29621

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    Belton Commercial Buildings and Land
    $650,000
    8,180 SF
    Belton Commercial Buildings and Land

    Two commercial buildings and land available in Belton, SC.

    1513 Anderson St, Belton, SC 29627

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    Downtown Anderson Two-Story Office Building
    $595,000
    4,300 SF
    Downtown Anderson Two-Story Office Building

    Two-story office building in downtown Anderson with private parking.

    1008 North Main Street, Anderson, SC 29621

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    Office Cottage Near Downtown Anderson
    $215,000
    1,400 SF
    Office Cottage Near Downtown Anderson

    Office space near downtown, AnMed Hospital, and Anderson University.

    609 Bonham Court, Anderson, SC 29621

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    Move-in Ready Office Space
    $185,000
    Move-in Ready Office Space

    Professional office space with excellent location and high traffic.

    400 N Fant Street, Anderson, SC 29621

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    Anderson Office Building For Sale
    $649,000
    4,550 SF
    Anderson Office Building For Sale

    Well-located office building near Clemson Boulevard and AnMed Medical Center.

    131 Straight Drive, Anderson, SC 29625

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    Versatile Mixed-Use Commercial Property
    $750,000
    0.48 Acres
    Versatile Mixed-Use Commercial Property

    Over 5,000 sq ft commercial property with residential area.

    4327 Old Mill Road, Anderson, SC 29623

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    Freestanding Office Building For Sale
    $299,999
    1,715 SF
    Freestanding Office Building For Sale

    Two-story office building with basement, ideal for office use.

    1817 North Boulevard, Anderson, SC 29621

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    Commercial Lot in Mall Park
    Contact for pricing
    0.15 Acres
    Commercial Lot in Mall Park

    Centrally located commercial lot near shopping, dining, and civic center.

    29 Civic Center Boulevard, Anderson, SC 29625

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    Medical Office Building For Sale
    $1,050,000
    10,405 SF
    Medical Office Building For Sale

    Multi-tenant medical office building near AnMed campuses with development potential.

    102 Buford Avenue, Anderson, SC 29621

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    Anderson Flex Space Opportunity
    $115,999
    2,150 SF
    Anderson Flex Space Opportunity

    2,150 SF flex space near downtown Anderson for sale.

    1819 W Whitner St, Anderson, SC 29624

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    Residential Office with In-Law Suite
    $395,000
    Residential Office with In-Law Suite

    Brick home with finished basement, second kitchen, and separate entrance, offering flexible live/work and professional office potential.

    510 E Calhoun Street, Anderson, SC 29621

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    Anderson County, SC Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Anderson County, SC, showcased through 46 active listings on our real estate platform. These investment opportunities span a total of 114,168 square feet of properties for sale, with an estimated market value of $16,674,698.

    Sale prices for office spaces in Anderson County, SC start at $115,999, averaging $641,334, and reaching up to $2,304,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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