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Anderson County, SC Office Spaces for Sale

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48 properties
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Office Building with Covered Porch
Updated: Aug 24
Office Building with Covered Porch

402 W Main Street, Williamston, SC 29697

$324,900
0.87 AC lot
Approximately 11,200 vehicles pass the site daily
0.87‑acre office property at 402 W Main Street, Williamston, SC 29697
Four private offices plus lobby, kitchen, breakroom, and bathroom
Covered front porch and refinished hardwood floors
RC zoning with established businesses nearby
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Brick Office Building with Eight Offices
Updated: Jul 7
Brick Office Building with Eight Offices

203 N Hamilton Street, Williamston, SC 29697

$279,900
0.47 AC lot
Over 1850 square feet in a brick office building
8 offices with 4 entrances, 2 - 1/2 baths, and a kitchenette
0.47‑acre corner lot with plenty of parking
High traffic volume and visibility near schools and a local hardware store
Natural gas and forced‑air heating with public water service
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Office Building with Private Offices
Office Building with Private Offices

713 Anderson Street, Belton, SC 29627

$290,000
0.45 AC lot

Existing reception, storage, and restroom areas support a range of professional office configurations.

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Flex Building With Drive-In Doors
Flex Building With Drive-In Doors

1007 South Murray Avenue, Anderson, SC 29624

$525,000
9,780 sqft 0.85 AC lot

General Commercial zoning combines renovated office/showroom space with warehouse functionality.

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Flex Space with Roll-Up Bay
Flex Space with Roll-Up Bay

3499 East River Street, Anderson, SC 29621

$429,000
0.64 AC lot

Includes finished office areas alongside unfinished warehouse space for a flexible commercial layout.

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Tenant-Occupied Flex Space with Office and Warehouse
Tenant-Occupied Flex Space with Office and Warehouse

3361 Highway 29 N, Belton, SC 29697

$595,000
2.00 AC lot

Tenant-occupied flex space with finished office, heated warehouse/shop, three bay doors, and a fenced storage yard.

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Two-Building Office Property
Two-Building Office Property

4450 HIGHWAY 24, Anderson, SC 29626

$420,000
0.80 AC lot

Two currently rented buildings offer an established office-use configuration on a 0.8-acre site.

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Prime Anderson Commercial Corner Property
Prime Anderson Commercial Corner Property

110 E Greenville St, Anderson, SC 29621

$2,300,000
14,000 sqft 1.21 AC lot

Multi-tenant property on 1.21 acres in Anderson's commercial hub.

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Two-Story Shopping Center
Two-Story Shopping Center

2406, 2408, 2410 N Main Street, Anderson, SC 29621

$1,990,000

Multi-suite commercial property with rear access from Whitehall Avenue.

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Brick Office Building
Brick Office Building

203 N Hamilton Street, Williamston, SC 29697

$279,900
0.47 AC lot

Corner-lot professional property with multiple offices, a kitchenette, porch, and parking near schools and a local hardware store.

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Medical Office Building For Sale
Medical Office Building For Sale

102 Buford Avenue, Anderson, SC 29621

$1,050,000
10,405 sqft

Multi-tenant medical office building near AnMed campuses with development potential.

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Multi-Office Professional Suite
Multi-Office Professional Suite

212 E Shockley Ferry Road, Anderson, SC 29624

$169,000

Configured for professional services with private rooms, reception space, and flexible work areas near downtown Anderson.

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Three-Level Live-Work Property
Three-Level Live-Work Property

4327 Old Mill Road, Anderson, SC 29623

$750,000
0.48 AC lot

Flexible layout combines residential accommodations with office and flex areas.

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Versatile Property Near AnMed Hospital
Versatile Property Near AnMed Hospital

1502 E Greenville St, Anderson, SC 29621

$925,000
4,300 sqft 0.61 AC lot

Versatile 4,300 SF property suitable for office or retail.

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Brick Live-Work Property
Brick Live-Work Property

510 E Calhoun Street, Anderson, SC 29621

$350,000

Residential Office zoning supports flexible living arrangements, professional office use, or boutique business space.

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Commercial Land with Paved Lot
Commercial Land with Paved Lot

805 Hwy 28 Bypass, Anderson, SC 29624

$169,900

Paved commercial site with an existing single-wide currently used as office space.

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Freestanding Office Building For Sale
Freestanding Office Building For Sale

1817 North Boulevard, Anderson, SC 29621

$289,999
1,715 sqft 0.22 AC lot

Two-story office building with basement, ideal for office use.

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Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

400 N Fant Street, Anderson, SC 29621

$185,000

Front suite with a medical layout, reception, waiting area, private offices, and separate exterior entrances.

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Retail Building with Parking
Retail Building with Parking

2816 East North Avenue, Anderson, SC 29625

$210,000
1,100 sqft 0.33 AC lot

Updated interior includes hardwood flooring, fresh paint, a bathroom, and kitchenette.

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Live-Work Home with Commercial Zoning
Live-Work Home with Commercial Zoning

1400 Pearman Dairy Road, Anderson, SC 29625

$164,900
0.52 AC lot

Versatile home on 28 Bypass with 3 beds, 1.5 baths, updated kitchen, and new HVAC installed in 2024.

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Belton Commercial Building in District
Belton Commercial Building in District

201 O Neal Street, Belton, SC 29627

$250,000
2,250 sqft 0.22 AC lot

Commercial building in Belton's Social District, suitable for various uses.

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Two-Sided Mixed-Use Commercial Building
Two-Sided Mixed-Use Commercial Building

1400 S FANT Street, Anderson, SC 29624

$120,000

Commercial building with a flexible two-sided layout for retail, office, or mixed-use operations.

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Flex Building with Office and Warehouse
Flex Building with Office and Warehouse

3499 East River Street, Anderson, SC 29621

$429,000
2,430 sqft

Well-maintained 1970s flex building offers finished office space and unfinished warehouse area with a 9' roll-up bay door.

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Downtown Brick Office Building
Downtown Brick Office Building

109 W Calhoun Street, Anderson, SC 29621

$156,500

Heated commercial space offers rear access, concrete flooring, and a city-installed parking lot with new lighting.

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Anderson County, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Anderson County, SC, showcased through 48 active listings on our real estate platform. These investment opportunities span a total of 129,460 square feet of properties for sale, with an estimated market value of $16,177,749.

Sale prices for office spaces in Anderson County, SC start at $120,000, averaging $521,862, and reaching up to $2,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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