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    Lancaster County, SC Office Spaces for Sale

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    Columbia, SC Greenville, SC Hilton Head Island, SC Myrtle Beach, SC Spartanburg, SC Aiken, SC Anderson, SC Charleston, SC
    13 properties
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    Commercial Land with Office Building
    Updated: Sep 8
    Commercial Land with Office Building

    731 S Market Street, Lancaster, SC 29720

    $140,000
    1.62 AC lot
    1.62‑acre commercial parcel
    B3 General Business zoning
    Existing office building positioned along the edge of the lot
    Approximately 270 feet of frontage on S Market Street
    Public water and sewer on site
    View details
    Medical Office Building
    Updated: May 4
    Medical Office Building

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1.76 AC lot
    More than 1,100 square feet of building area
    1.76‑acre property comprising two lots
    Previously used as a dental office
    Electric heating and air conditioning
    Zoned KER; built in 1965
    View details
    Two-Building Office Property
    Two-Building Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot

    One building is configured for medical office use, while the other includes open space and upper-level workstations.

    View details
    Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
    Medical Office on Two Lots
    Medical Office on Two Lots

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1.76 AC lot

    The property includes electric heating and air conditioning within Kershaw town limits.

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    Former Medical Office Space
    Former Medical Office Space

    110 South Cleveland Street, Kershaw, SC 29067

    $150,000
    3,550 sqft

    3,350 SF medical office with 11 parking spaces.

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    Historic Mixed-Use Retail/Office Buildings
    Historic Mixed-Use Retail/Office Buildings

    209-227 S. Main Street, Lancaster, SC 29720

    Contact for pricing
    29,151 sqft

    Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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    Downtown Mixed-Use Redevelopment Property
    Downtown Mixed-Use Redevelopment Property

    210 S. White Street, Lancaster, SC 29720

    Contact for pricing
    22,251 sqft

    Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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    Office Building
    Office Building

    312 N Main Street N, Lancaster, SC 29720

    Contact for pricing
    2,706 sqft

    Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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    1930s Retail/Office Building Portfolio
    1930s Retail/Office Building Portfolio

    116 Arch Street, Lancaster, SC 29720

    Contact for pricing
    29,444 sqft

    Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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    Versatile Commercial Building in Lancaster
    Versatile Commercial Building in Lancaster

    302 N White St, Lancaster, SC 29720

    $325,000

    Two-story commercial building with offices in downtown Lancaster, SC.

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    Medical Office Buildings Near MUSC
    Medical Office Buildings Near MUSC

    1201 Colonial Commons Ct, Lancaster, SC 29720

    $975,000

    Two professional buildings suitable for medical or office use.

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    Office Building with Live-Work Use
    Office Building with Live-Work Use

    36-305 E Arch St, Lancaster, SC 29720

    $250,000

    B-2 zoning supports residential occupancy alongside a business, with parking and accessible entry.

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    Commercial Land with Office Building
    Commercial Land with Office Building

    731 S Market St, Lancaster, SC 29720

    $140,000

    B3-zoned parcel with an existing office building and city utilities on site.

    View details
    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 13 Active listings in Lancaster County, SC, we suggest exploring several alternatives: similar 59 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Brick Storefront Property
    Brick Storefront Property

    2836 Lynwood Drive, Lancaster, SC 29720

    $149,900
    0.47 AC lot

    Commercial space with central air, electric heat, carpet flooring, and a bathroom.

    View details
    Light Industrial Land For Sale
    Light Industrial Land For Sale

    00 Fork Hill Road, Kershaw, SC 29067

    $90,000

    Land zoned for light industrial use with possible residential rezoning.

    View details
    Commercial Land in Pageland, SC
    Commercial Land in Pageland, SC

    605 E Mcgregor Street, Pageland, SC 29728

    $495,000
    1.91 AC lot

    Two parcels totaling 1.91 acres zoned for commercial and residential use.

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    Highway Frontage Commercial Land
    Highway Frontage Commercial Land

    510 Van Lingle Mungo Boulevard, Pageland, SC 29728

    $255,000
    2.69 AC lot

    R8-zoned tract with public sewer and access from two roads.

    View details

    Off-Market Properties in Lancaster County, SC

    Consider similar Off-Market properties in Lancaster County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    979 University Dr
    OFFICE (GENERAL)

    979 University Dr, Lancaster, SC 29720

    Estimated value:
    $180,000
    1,584 sqft 130.00 AC lot
    View details
    713 Main St
    OFFICE (GENERAL)

    713 Main St, Lancaster, SC 29720-3644

    Estimated value:
    $140,000
    1,128 sqft 234.00 AC lot
    View details
    312 Miller St
    OFFICE (GENERAL)

    312 Miller St, Lancaster, SC 29720

    Estimated value: by Request
    1,467 sqft 4.40 AC lot
    View details
    Hwy 914
    OFFICE (GENERAL)

    Hwy 914, Lancaster, SC 29720

    Estimated value:
    $345,000
    2,586 sqft 200.00 AC lot
    View details
    503 Meeting St
    OFFICE (GENERAL)

    503 Meeting St, Lancaster, SC 29720-2323

    Estimated value:
    $190,000
    1,210 sqft 75.00 AC lot
    View details
    1320 Hwy 9th W Byp
    MEDICAL BUILDING

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

    Estimated value: by Request
    1,320 sqft 70.00 AC lot
    View details
    312 Main St
    OFFICE (GENERAL)

    312 Main St, Lancaster, SC 29720-2132

    Estimated value:
    $535,000
    5,644 sqft 130.00 AC lot
    View details
    9160 Northfield Dr
    OFFICE (GENERAL)

    9160 Northfield Dr, Fort Mill, SC 29707-6540

    Estimated value:
    $805,000
    6,670 sqft 8.46 AC lot
    View details
    2583 Kershaw Camden Hwy
    OFFICE (GENERAL)

    2583 Kershaw Camden Hwy, Lancaster, SC 29720-6855

    Estimated value:
    $340,000
    8,060 sqft 0.67 AC lot
    View details
    1104 Lockwood Ln
    OFFICE (GENERAL)

    1104 Lockwood Ln, Lancaster, SC 29720-6217

    Estimated value:
    $110,000
    2,240 sqft 283.00 AC lot
    View details
    Catawba St
    OFFICE (GENERAL)

    Catawba St, Lancaster, SC 29720

    Estimated value:
    $415,000
    3,128 sqft 100.00 AC lot
    View details

    Lancaster County, SC Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Lancaster County, SC, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 87,102 square feet of properties for sale, with an estimated market value of $3,355,000.

    Sale prices for office properties in Lancaster County, SC start at $140,000, averaging $372,777, and reaching up to $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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