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Lancaster County, SC Office Spaces for Sale

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11 properties
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Medical Office on Acreage
Updated: May 4
Medical Office on Acreage

104 S Ashe Street, Kershaw, SC 29067

$200,000
1.76 AC lot
More than 1,100 square feet of building area
1.76‑acre parcel consisting of 2 lots
Previously operated as a dental office
Electric heat and air conditioning
Located within Kershaw town limits
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Commercial Land with Office Building
Updated: Sep 8
Commercial Land with Office Building

731 S Market Street, Lancaster, SC 29720

$140,000
1.62 AC lot
1.62‑acre commercial parcel
B3 General Business zoning
Existing office building positioned along the edge of the lot
Approximately 270 feet of frontage on S Market Street
Public water and sewer on site
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Two-Building Medical Office Property
Two-Building Medical Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000
0.82 AC lot

Professional office compound with medical layouts, reception areas, waiting rooms, and separate work areas across two buildings.

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Former Medical Office Space
Former Medical Office Space

110 South Cleveland Street, Kershaw, SC 29067

$150,000
3,550 sqft

3,350 SF medical office with 11 parking spaces.

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Historic Mixed-Use Retail/Office Buildings
Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

Contact for pricing
29,151 sqft

Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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Downtown Mixed-Use Redevelopment Property
Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

Contact for pricing
22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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1930s Retail/Office Building Portfolio
1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

Contact for pricing
29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Office Building
Office Building

312 N Main Street N, Lancaster, SC 29720

Contact for pricing
2,706 sqft

Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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Medical Office Buildings Near MUSC
Medical Office Buildings Near MUSC

1201 Colonial Commons Ct, Lancaster, SC 29720

$975,000

Two professional buildings suitable for medical or office use.

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Versatile Commercial Building in Lancaster
Versatile Commercial Building in Lancaster

302 N White St, Lancaster, SC 29720

$325,000

Two-story commercial building with offices in downtown Lancaster, SC.

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Office Building with Live-Work Use
Office Building with Live-Work Use

36-305 E Arch St, Lancaster, SC 29720

$250,000

B-2 zoning supports residential occupancy alongside a business, with parking and accessible entry.

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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 11 Active listings in Lancaster County, SC, we suggest exploring several alternatives: similar 61 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Brick Storefront Property
Brick Storefront Property

2836 Lynwood Drive, Lancaster, SC 29720

$149,900
0.47 AC lot

Commercial space with central air, electric heat, carpet flooring, and a bathroom.

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Light Industrial Land For Sale
Light Industrial Land For Sale

00 Fork Hill Road, Kershaw, SC 29067

$90,000

Land zoned for light industrial use with possible residential rezoning.

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Commercial Land in Pageland, SC
Commercial Land in Pageland, SC

605 E Mcgregor Street, Pageland, SC 29728

$495,000
1.91 AC lot

Two parcels totaling 1.91 acres zoned for commercial and residential use.

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Highway Frontage Commercial Land
Highway Frontage Commercial Land

510 Van Lingle Mungo Boulevard, Pageland, SC 29728

$255,000
2.69 AC lot

R8-zoned tract with public sewer and access from two roads.

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Off-Market Properties in Lancaster County, SC

Consider similar Off-Market properties in Lancaster County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

979 University Dr
OFFICE (GENERAL)

979 University Dr, Lancaster, SC 29720

Estimated value:
$180,000
1,584 sqft 130.00 AC lot
View details
713 Main St
OFFICE (GENERAL)

713 Main St, Lancaster, SC 29720-3644

Estimated value:
$140,000
1,128 sqft 234.00 AC lot
View details
312 Miller St
OFFICE (GENERAL)

312 Miller St, Lancaster, SC 29720

Estimated value:
by Request
1,467 sqft 4.40 AC lot
View details
Hwy 914
OFFICE (GENERAL)

Hwy 914, Lancaster, SC 29720

Estimated value:
$345,000
2,586 sqft 200.00 AC lot
View details
503 Meeting St
OFFICE (GENERAL)

503 Meeting St, Lancaster, SC 29720-2323

Estimated value:
$190,000
1,210 sqft 75.00 AC lot
View details
1320 Hwy 9th W Byp
MEDICAL BUILDING

1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

Estimated value:
by Request
1,320 sqft 70.00 AC lot
View details
312 Main St
OFFICE (GENERAL)

312 Main St, Lancaster, SC 29720-2132

Estimated value:
$535,000
5,644 sqft 130.00 AC lot
View details
9160 Northfield Dr
OFFICE (GENERAL)

9160 Northfield Dr, Fort Mill, SC 29707-6540

Estimated value:
$805,000
6,670 sqft 8.46 AC lot
View details
2583 Kershaw Camden Hwy
OFFICE (GENERAL)

2583 Kershaw Camden Hwy, Lancaster, SC 29720-6855

Estimated value:
$340,000
8,060 sqft 0.67 AC lot
View details
1104 Lockwood Ln
OFFICE (GENERAL)

1104 Lockwood Ln, Lancaster, SC 29720-6217

Estimated value:
$110,000
2,240 sqft 283.00 AC lot
View details
Catawba St
OFFICE (GENERAL)

Catawba St, Lancaster, SC 29720

Estimated value:
$415,000
3,128 sqft 100.00 AC lot
View details
419 Meeting St
MEDICAL BUILDING

419 Meeting St, Lancaster, SC 29720-2321

Estimated value:
$750,000
4,600 sqft 22.00 AC lot
View details
1091 Rebound Rd
OFFICE (GENERAL)

1091 Rebound Rd, Lancaster, SC 29720

Estimated value:
$275,000
1,994 sqft 22.73 AC lot
View details

Lancaster County, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Lancaster County, SC, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 87,102 square feet of properties for sale, with an estimated market value of $3,015,000.

Sale prices for office spaces in Lancaster County, SC start at $140,000, averaging $430,714, and reaching up to $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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