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    Florence, SC Office Spaces for Sale

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    Historic Downtown Florence Commercial Property
    Updated: Oct 4, 2024
    Historic Downtown Florence Commercial Property

    329 N Irby St, Florence, SC 29501

    $1,100,000
    12,411 sqft 1.55 AC lot
    Historic property listed on the National Register of Historic Places.
    Located in the heart of downtown Florence.
    Situated on the corner of Irby and Darlington Streets.
    Building size of approximately 12,411 square feet.
    Property occupies approximately 1.55 acres.
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    This listing looks promising.

    Here's a quick look at some key insights for

    329 N Irby St, Florence, SC 29501

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    • Est. Cap Rate

      8.9%
      Above avg (5.9%)

    • Est. NOI

      $98K
      Annual

    • Price @ 7% Cap

      $1.4M
      Above asking

    • Last Sold

      Jun 2021
      $24K

    • Property Type

      Auto Repair, Garage
      Built 1948
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    Medical Office Building with Parking
    Updated: Jul 10
    Medical Office Building with Parking

    1706 2nd Loop Rd., Florence, SC 29501

    $1,650,000
    8,291 sqft 1.34 AC lot
    8,300 sq ft commercial facility on 1.34 acres with CI zoning
    Former cardiology practice with 13 exam rooms plus X‑ray room
    Includes reception lobby, executive and administrative offices, and board room
    Extensive storage including a fully floored attic
    Covered patient drop‑off, four‑bay carport, and 62 parking spaces
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    Historic Downtown Office Building
    Historic Downtown Office Building

    248-260 W Evans st., Florence, SC 29501

    $2,700,000
    16,304 sqft 1.47 AC lot

    Historic office building with multiple suites and ample on-site parking in downtown Florence.

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    Office Property with Parking
    Office Property with Parking

    2228 W Palmetto St., Florence, SC 29501

    $250,000
    1,405 sqft 0.31 AC lot

    Office space on a 0.31-acre lot with parking and strong visibility along W Palmetto St in Florence.

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    Remodeled Medical Office Building
    Remodeled Medical Office Building

    910 W Evans st, Florence, SC 29501

    $300,000
    2,165 sqft 0.27 AC lot

    Turnkey, fully rebuilt office suite with treatment-room style spaces, new HVAC, and updated plumbing and electrical.

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    Historic Downtown Office Building
    Historic Downtown Office Building

    260 W Evans St, Florence, SC 29501

    $2,700,000
    16,000 sqft 1.47 AC lot

    A 16,000-square-foot historic office building with multiple suites, including a law firm and other tenants, plus over 100 parking spaces.

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    Commercial Office Property with Parking
    Commercial Office Property with Parking

    2228 W Palmetto St., Florence, SC 29501

    $250,000
    1,405 sqft

    Office-focused commercial property along a high-traffic corridor, offering visibility, accessibility, and ample on-site parking.

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    McLeod Physician Associates For Sale
    McLeod Physician Associates For Sale

    1540 American Dr, Florence, SC

    $1,384,320
    2,666 sqft 0.59 AC lot

    2,666 SF medical office in Florence, SC for sale.

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    Downtown Florence Business Technology Center
    Downtown Florence Business Technology Center

    187 E Evans St, Florence, SC

    $12,000,000
    119,567 sqft 3.29 AC lot

    Office building in downtown Florence with investment and value-add potential.

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    Historic Downtown Florence Building For Sale
    Historic Downtown Florence Building For Sale

    248,258, and 268 W. Evans St., Florence, SC 29501

    $2,700,000
    16,304 sqft 1.47 AC lot

    16,000 SF historic building in downtown Florence for sale.

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    Office/Retail Conversion Opportunity
    Office/Retail Conversion Opportunity

    2901 W Palmetto Street, Florence, SC 29501

    $400,000
    2,600 sqft 1.60 AC lot

    2600 SF residence on 1.6 acres, suitable for conversion.

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    Freestanding Office Building For Sale
    Freestanding Office Building For Sale

    1221 West Evans Street, Florence, SC 29501

    $175,000
    1,085 sqft

    Leased office building with immediate income potential in Florence.

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    South Irby Street Commercial Lot
    South Irby Street Commercial Lot

    623 South Irby Street, Florence, SC 29501

    $255,000
    0.46 AC lot

    0.46 acre lot suitable for retail or office development.

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    Industrial Warehouse with Development Potential
    Industrial Warehouse with Development Potential

    906 S Church St, Florence, SC 29506

    $2,190,000
    95,590 sqft 7.34 AC lot

    95,590 SF industrial warehouse on 7.34 acres for sale.

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    Versatile Office Building For Sale
    Versatile Office Building For Sale

    603 W Palmetto Street, Florence, SC 29501

    $262,500
    2,004 sqft

    Functional office building in high traffic area, ideal for professionals.

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    Office Building Near Downtown Florence
    Office Building Near Downtown Florence

    604 S Coit, Florence, SC 29501

    Contact for pricing
    2,481 sqft

    Office building with private offices, conference room, and parking.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 16 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 56 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Timmonsville Medical Office Building
    Timmonsville Medical Office Building

    101 Market St, Timmonsville, SC 29161

    $125,000
    1,968 sqft 0.20 AC lot

    Well-maintained 2,000 SF building suitable for various office uses.

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    Timmonsville Medical Office Building
    Timmonsville Medical Office Building

    101 W Market St, Timmonsville, SC 29161

    $125,000
    1,978 sqft

    Well-maintained building suitable for medical or business office.

    View details
    Darlington Office Units For Sale
    Darlington Office Units For Sale

    102-116 Exchange Street, Darlington, SC 29532

    $199,000

    Eight office units near the courthouse in Darlington, South Carolina.

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    Versatile Commercial Property Near Florence
    Versatile Commercial Property Near Florence

    1133 E McLver Road, Darlington, SC 29532

    Contact for pricing
    9,258 sqft 4.00 AC lot

    Two buildings on +/- 4 acres, ideal for business.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Development-Ready Commercial Land Site
    Development-Ready Commercial Land Site

    917 S Cashua Drive, Florence, SC 29501

    $980,000
    4.76 AC lot

    4.76-acre B3-zoned parcel on a four-lane corridor with SCDOT-reported traffic near major daily-use anchors.

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    Prime Commercial Lot in Florence
    Prime Commercial Lot in Florence

    1700 E Palmetto St, Florence, SC 29506

    $2,750,000
    1 sqft 7.96 AC lot

    7.96-acre commercial lot near McLeod Hospital and Florence Airport.

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    Florence Area Investment Opportunity
    Florence Area Investment Opportunity

    5723 E National Cemetery Rd, Florence, SC 29506

    Contact for pricing

    Prime land in Florence, SC, with development potential.

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    Commercial Land with Income Billboard
    Commercial Land with Income Billboard

    S Governor Williams Highway, Darlington, SC 29532

    $249,000
    4.79 AC lot

    Commercial-zoned land featuring an income-producing billboard and potential city annexation based on contiguity.

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    Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    316 Mcqueen St
    MEDICAL BUILDING

    316 Mcqueen St, Florence, SC 29501-4723

    Value Estimation by Request
    1,470 sqft 0.18 AC lot
    View details
    511 Evans St
    OFFICE BUILDING

    511 Evans St, Florence, SC 29501-3407

    Value Estimation by Request
    2,145 sqft
    View details
    511 Evans St
    OFFICE BUILDING

    511 Evans St, Florence, SC 29501-3407

    Value Estimation by Request
    1,250 sqft 0.30 AC lot
    View details
    908 Evans St
    OFFICE BUILDING

    908 Evans St, Florence, SC 29501-3442

    Value Estimation by Request
    1,430 sqft 0.27 AC lot
    View details
    3036 Caterpillar Ln
    OFFICE BUILDING

    3036 Caterpillar Ln, Florence, SC 29506-8109

    Value Estimation by Request
    672 sqft 5.65 AC lot
    View details
    1530 Mclure Ct
    MEDICAL BUILDING

    1530 Mclure Ct, Florence, SC 29505-6174

    Value Estimation by Request
    10,148 sqft 1.22 AC lot
    View details
    1937 Palmetto St
    OFFICE BUILDING

    1937 Palmetto St, Florence, SC 29506-3606

    Value Estimation by Request
    2,907 sqft 0.72 AC lot
    View details
    262 Cheves St
    DENTAL BUILDING

    262 Cheves St, Florence, SC 29501-4404

    Value Estimation by Request
    1,460 sqft 0.52 AC lot
    View details

    Florence, SC Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Florence, SC, showcased through 16 active listings on our real estate platform. These investment opportunities span a total of 297,797 square feet of properties for sale, with an estimated market value of $28,061,820.

    Sale prices for office spaces in Florence, SC start at $175,000, averaging $2,004,415, and reaching up to $12,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 14
    Office buildings 12
    Medical Office Space 5

    Demographics Overview

    Population 92K
    Population Growth (5Y) -1.5%
    Median Household Income $61,793
    College Educated 17.4%

    High-Yield Neighborhoods for Investment

    Identify Florence submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29501 $619K
    29506 $2.2M

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Florence County

    New Delisted

    Total CRE Inventory on Market (SF)

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