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    South Carolina Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
    3,005 properties
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    Second-Floor Office Unit
    Second-Floor Office Unit

    3260 Holmestown Rd., Myrtle Beach, SC 29588

    $2,150/Mo
    7–12 people  1,800 sqft  Floor 2
    Highway access

    Flexible office layout with private rooms, collaborative workspace, reception area, storage, signage, and convenient parking.

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    Charleston Retail Development Opportunity
    Charleston Retail Development Opportunity

    1925 Essex Farms Drive, Charleston, SC 29414

    $42 SF/Yr
    5,100 sqft

    Strategically positioned retail development opportunity in Charleston's fastest-growing submarket.

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    Warehouse with Drive-Through Access
    Warehouse with Drive-Through Access

    3720 Wesley St., Myrtle Beach, SC 29579

    $7,500/Mo
    4,000 sqft  9,000 sqft building  3 drive-in  9,000 sqft warehouse

    Warehouse space includes climate-controlled area, multiple roll-up doors, and a dedicated adjacent lay-down yard.

    Outdoor storage
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    Proposed Corner Retail Strip Center
    Proposed Corner Retail Strip Center

    Sophie Rd & SC-544, Conway, SC 29526

    $27.50 SF/Yr
    27,300 sqft
    Highway access

    Proposed 27,300 SF strip center at the corner of Hwy 544 with 670' frontage on a high-traffic corridor.

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    Air-Conditioned Flex Space
    Air-Conditioned Flex Space

    1471 Dividend Loop Suite B, Myrtle Beach, SC 29577

    $8,750/Mo
    7,500 sqft  15,000 sqft building  22 ft clear  2 drive-in
    Highway access  Road access

    Subdividable industrial space with drive-in loading, three-phase power, sprinkler protection, and build-to-suit office options.

    Sprinklered
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    Open-Layout Retail Space
    Open-Layout Retail Space

    1810 Boundary Street, Beaufort, SC 29902

    $3,000/Mo
    Multi-tenant  1,750 sqft  Built 1946
    33,600 VPD

    A glass storefront and shared parking serve this commercially zoned suite.

    Open layout  Glass storefront  Shared on-site parking  Signage availability
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    Mount Pleasant Retail/Office/Medical Space
    Mount Pleasant Retail/Office/Medical Space

    1123 Queensborough Boulevard, Mount Pleasant, SC 29464

    $30 SF/Yr
    15–26 people  3,949 sqft

    3,949 SF space ideal for retail, office, or medical.

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    Flex Space with Garage
    Flex Space with Garage

    1010 5th Ave. N #Suite 106, Surfside Beach, SC 29575

    $1,100/Mo
    980 sqft  Built 1981

    An office-and-storage layout includes a kitchenette, restroom, and shower.

    25 parking spaces  Sitting area  Kitchenette  Restroom/shower
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    Warehouse with Office and Roll-Up Doors
    Warehouse with Office and Roll-Up Doors

    11 Demedicis Boulevard, Warrenville, SC 29851

    Modified gross
    $3,950/Mo
    10,000 sqft  20 ft clear  2 drive-in  Built 2011
    Highway access  Road access  RUD

    Warehouse suite includes an office, break room, private bathroom, and two end-loading grade-level roll-up doors behind a security gate.

    Kitchen/break room  Private bathroom  Security gate
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    Freestanding Industrial Cold Storage Facility
    Freestanding Industrial Cold Storage Facility

    816 Buff St, West Columbia, SC 29169

    $8,400/Mo
    8,400 sqft  22 ft clear  2 docks + 1 drive-in
    Highway access  LM

    Freestanding, fully insulated industrial building with a walk-in freezer and multiple loading doors for temperature-controlled operations.

    Walk-in freezer
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    Renovated Flex Space with Open Layout
    Renovated Flex Space with Open Layout

    2467 Savannah Hwy, Charleston, SC 29414

    Melrose
    $1,900/Mo
    3,704 sqft  5 buildings
    Highway access  Road access

    Open-plan suites include bathrooms and a break area.

    Bathrooms  Break area
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    Warehouse with Loading Docks
    Warehouse with Loading Docks

    358 Buck Island Road, Bluffton, SC 29910

    $16 SF/Yr
    12,500 sqft  25 ft clear  2 docks + 1 drive-in  Built 1998
    Highway access  Road access

    Industrial warehouse with dock and drive-up loading, direct Buck Island Road access, and proximity to major regional routes.

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    Warehouse with Drive-Through Access
    Warehouse with Drive-Through Access

    3319-3320 Biedler Street, North Charleston, SC 29418

    $17.50 SF/Yr
    7,800 sqft

    Renovations are underway, with planned office improvements and a partially enclosed outdoor area.

    Outdoor storage  Fenced yard
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    Freestanding Brick Office Building
    Freestanding Brick Office Building

    1598 Columbia Highway, Aiken, SC 29801

    $1,800/Mo
    5–9 people  1,494 sqft  Built 1983  0.83 acres
    5 private offices  1 meeting rooms  Highway access + Road access

    Five offices accompany a conference room, kitchen and break area, data room, and storage.

    5 parking spaces  Tile floors  Chair rails  Handicap-accessible bathroom
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    Flex Space with Dock Access
    Flex Space with Dock Access

    775 Woodruff Road, Greenville, SC 29607

    Triple net (NNN)
    $15 SF/Yr
    4,690 sqft  2 docks + 2 drive-in  900 sqft office  3,790 sqft warehouse
    Highway access  Road access  S-1

    Office and warehouse configuration with drive-in and dock-high loading, monument signage, and S-1 zoning.

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    Seaboard Street Commercial/Industrial Site
    Seaboard Street Commercial/Industrial Site

    Myrtle Beach, SC 29577

    Triple net (NNN)
    $16 SF/Yr
    3,200 sqft

    Commercial/industrial site for lease with frontage on Seaboard Street.

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    Unconditioned Warehouse Unit
    Unconditioned Warehouse Unit

    1200 Glenns Bay Rd, Surfside Beach, SC 29575

    $14.40 SF/Yr
    1,000 sqft  Built 1994  1,000 sqft warehouse
    Highway access  Road access

    Compact warehouse space with overhead-door access, restroom, and dedicated parking within Surfside Beach city limits.

    2 parking spaces
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    Office Unit with Elevator Access
    Office Unit with Elevator Access

    203 West Main Street G3, Lexington, SC 29072

    $98 SF/Yr
    1 person  33 sqft  Built 2010

    Building amenities include a conference room, kitchenette, waiting room, restrooms, and internet availability.

    Conference room  Break rooms/kitchenette  Waiting room  Restrooms
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    Georgetown Historic District Retail Space
    Georgetown Historic District Retail Space

    718 Front St, Georgetown, SC 29440

    $3,800/Mo
    1,200 sqft  Built 1937

    Move-in ready retail space in Georgetown's Historic District.

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    Retail Space in Strip Center
    Retail Space in Strip Center

    2511 Broad St, Camden, SC 29020

    $1,650/Mo
    Multi-tenant  1,650 sqft  13,000 GLA

    Retail suite available within a shopping center on Broad Street.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    116 Professional Park Dr., Conway, SC 29526

    $10,634/Mo
    3,988 sqft  Built 2026  brick

    Clinical layout includes private offices, a laboratory, and dedicated space for medical technicians.

    25 parking spaces
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    Office Suite with Conference Room
    Office Suite with Conference Room

    121 Professional Ln. #Unit B, Pawleys Island, SC 29585

    $2,125/Mo
    6–10 people  1,500 sqft
    Highway access

    A dedicated meeting room, kitchen area and restroom support daily office operations.

    Private conference room  Fully equipped kitchen area  Modern restroom facilities  Abundant natural light
    View details
    Endcap Retail Suite
    Endcap Retail Suite

    984 - 996 South Broad Street, Clinton, SC 29325

    $9 SF/Yr
    Multi-tenant  1,300 sqft  Built 1985
    6,200 VPD

    End-cap space within a 4-tenant shopping center, featuring a blank-slate interior and ample on-site parking.

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    Class A LEED Silver Office Units
    Class A LEED Silver Office Units

    110 East Court Street, Greenville, SC 29601

    $49.50 SF/Yr
    87–146 people  21,928 sqft

    Flexible Class A office space with LEED Silver certification in downtown Greenville.

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