South Carolina Commercial Real Estate for Lease

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Columbia, SC Greenville, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
3,005 properties
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Second-Floor Office Suite
Second-Floor Office Suite

101 Ladys Island, Beaufort, SC 29907

Gross
$1,000/Mo
1 space  197 sqft  Built 2025  2-story

The office includes two windows, shared kitchenette and bathrooms, dedicated fiber internet, and on-site parking.

Shared kitchenette  Bathrooms  Covered porch  Dedicated fiber internet
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Forestbrook Road Office Space
Forestbrook Road Office Space

2523 Forestbrook Road, Unit D, Myrtle Beach, SC 29579

$16 SF/Yr
5–9 people  1 space  1,400 sqft  Built 2007

1,400 SF office space in Myrtle Beach for lease.

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Fully Serviced Business Solutions at SC, Charleston - 115 Fairchild Street. Contact us today to book a tour!
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Serviced Offices with Business Support at SC, Columbia - Williams Street. Contact us today to book a tour!
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Industrial Manufacturing Space
Industrial Manufacturing Space

534 Pendleton St, Rock Hill, SC 29730

$5,500/Mo
1,891 sqft  Built 1958

Industrial manufacturing space available for lease near the intersection of Charlotte Ave and Pendleton St.

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Office Space For Lease
Office Space For Lease

7006 Pelham Rd, Greenville, SC 29615

$12 SF/Yr
10–16 people  2 spaces  2,500 sqft  Built 1995

First floor office space available for lease.

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Retail Suite with 6,000 SF
Retail Suite with 6,000 SF

1214 Saint Matthews Rd, Orangeburg, SC 29115

$10 SF/Yr
6,000 sqft

Retail suite 308 offers 6,000 SF of space available for lease.

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Freestanding Brick Office Building
Freestanding Brick Office Building

1598 Columbia Highway N, Aiken, SC 29801

$1,800/Mo
5–9 people  1,494 sqft  Built 1983  brick
5 private offices  1 meeting rooms  Highway access

Five private offices accompany a conference room, break area, data room, and accessible restroom.

5 parking spaces  Handicap-accessible bathroom  Kitchen/break room  Data room
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6,000 SF Secured Warehouse Facility
6,000 SF Secured Warehouse Facility

7710 Southrail Rd, North Charleston, SC 29420

Windsor Hill Plantation
$5,514/Mo
5,514 sqft  18 ft clear  3 drive-in
Highway access

Metal warehouse includes 500 SF of office space, three drive-in doors, and a 5,514 SF clear-span warehouse.

Fenced yard
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Flex Space with Fenced Yard
Flex Space with Fenced Yard

807 Seaboard St., Myrtle Beach, SC 29577

$4,266/Mo
625 sqft

WM-zoned flex property with offices, a roll-up door, and direct Seaboard Street frontage.

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Flex Space with Loading Dock
Flex Space with Loading Dock

4-11 Mathews Dr, Hilton Head Island, SC 29926

Triple net (NNN)
$18 SF/Yr
3,500 sqft  1 docks + 1 drive-in

Mixed-use flex space suites include a back loading dock and pull-up door, available immediately.

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Medical Office Suites with Ample Parking
Medical Office Suites with Ample Parking

1300 Hospital Dr, Mt Pleasant, SC 29464

$1,757/Mo
Multi-tenant  3,425 sqft  3-story
Highway access

Three-story medical office building offers suites for lease with ample on-site paved parking.

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Freestanding Office Building in Myrtle Beach
Freestanding Office Building in Myrtle Beach

1051 Shine Ave., Myrtle Beach, SC 29577

$10,632/Mo
25–42 people  6,379 sqft  Built 1960

Office building in The Market Common District for rent.

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Renovated Office Building For Rent
Renovated Office Building For Rent

1311 South Murray Avenue, Anderson, SC 29624

$1,300/Mo
5–8 people  1 space  1,300 sqft

Renovated office building with versatile space for rent.

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Industrial Warehouse Lease
Industrial Warehouse Lease

1800 Greeleyville Hwy, Manning, SC 29102

$2,000/Mo
10,250 sqft
Highway access

Industrial warehouse space is available for lease on a 5.87-acre parcel in Manning, SC with access to major highways.

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Medical Office Suite with Plumbing
Medical Office Suite with Plumbing

1264 Ribaut Road, Beaufort, SC 29902

$2,845/Mo
1,484 sqft  Built 1998  0.01 acres

Existing plumbing, a shower, and laundry hookups support medical, wellness, and other service-oriented operations.

10 parking spaces  Washer & dryer hookup  Large water heater  Ample existing plumbing
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Build-Out-Ready Mixed-Use Space
Build-Out-Ready Mixed-Use Space

413 Main Street S, New Ellenton, SC 29809

Triple net (NNN)
$800/Mo
510 sqft  Built 1948

Compact office or mixed-use space in New Ellenton with an NNN lease structure.

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Retail Space with Drive-Up Windows
Retail Space with Drive-Up Windows

5 S Church Street, Manning, SC 29102

$1,280/Mo
Multi-tenant  1,500 sqft

Commercial space with a lobby, high-ceiling back room, shared parking, and public water and sewer service.

Drive-thru  Drive up windows  Lobby area  Back room with high ceilings
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New Retail Space with Custom Buildout
New Retail Space with Custom Buildout

9601 Ocean Highway, Pawleys Island, SC 29585

$6,082/Mo
2,500 sqft

GC-zoned retail space under construction along Ocean Highway with tenant-ready infrastructure and flexible suite configurations.

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Office/Warehouse Flex Building
Office/Warehouse Flex Building

6650 Jet Park Road, North Charleston, SC 29406

Midland Park
$12,000/Mo
5,000 sqft  13 ft clear  5 drive-in  Heavy power
Highway access

Flex office/warehouse building with fenced gravel yard, multiple drive-in doors, 13-foot clear height, and three-phase power.

Outdoor storage  Fenced yard
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Office/Warehouse Space in North Industrial
Office/Warehouse Space in North Industrial

1460 Dividend Loop Unit C, Myrtle Beach, SC 29577

$5,833/Mo
5,000 sqft

5,000 SF office/warehouse space for lease in Myrtle Beach.

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Four-Office Second-Floor Suite
Four-Office Second-Floor Suite

1639 S Highway 17 #2nd Floor Office, North Myrtle Beach, SC 29582

$2,667/Mo
8–13 people  2,000 sqft  Built 1987  Floor 2
4 private offices  2 meeting rooms  Highway access + Road access

The office can be configured as one suite or divided into two smaller units, each with private offices and a conference room.

47 parking spaces
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Highway-Fronting Flex Space
Highway-Fronting Flex Space

1970 Highway 905 #Unit B, Conway, SC 29526

$2,166/Mo
1,625 sqft
Highway access  Road access  RE-4

The RE4-zoned unit supports warehouse, distribution, office, retail, and service-oriented uses.

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Three-Office Professional Suite
Three-Office Professional Suite

4214 Mayfair St. #Unit F, Myrtle Beach, SC 29577

$1,273/Mo
3–6 people  940 sqft
3 private offices

Reception space, a private restroom, and storage support a functional office layout.

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