Roanoke, VA Office Units for Rent & Lease

$15 SF/Yr

6,631 SF

Bank-Converted Office Building

301 McClanahan Street SW, Roanoke, VA 24014

Converted for office or medical use with renovated second-floor space and on-site parking for convenient access.

Former Wells Fargo bank branch with ~3,300 SF on two floors (total 6,631 SF).
Second‑floor office space was recently renovated and is ready for use.
First floor includes office space and a drive‑thru option if desired.
34 on‑site parking spaces for employees and visitors.
Multiple ingress/egress points for access flexibility.

Updated: Jun 1

View details

$3 SF/Yr

18,200 SF

Spacious Open Floorplan Office Space

3441 Brandon Ave SW, Roanoke, VA 24018

Large office space with flexible layout on Brandon Avenue.

High‑traffic location on Brandon Ave, ideal for businesses serving Southwest County, Downtown Roanoke, and surrounding areas.
Large ±18,200 sf space with a mostly open floorplan.
Flexible space that can be demised to fit various business needs.
Multiple bathrooms.
Owner willing to discuss tenant improvements at an adjusted lease rate.

Updated: Mar 6

View details

Brambleton Avenue Commercial Space Available

$22 SF/Yr

1,700 SF

Brambleton Avenue Commercial Space Available

1,700 SF space suitable for medical, office, or retail.

5002 Brambleton Ave, Roanoke, VA 24018

View details

$10 SF/Yr

2,600 SF

Downtown Roanoke Office or Retail

Office or retail space in downtown Roanoke.

9 Franklin Rd SW, Roanoke, VA 24011

View details

$12 SF/Yr

7,260 SF

Retail/Office Space on Brambleton Ave

Well-maintained retail/office space with excellent road visibility.

Roanoke, VA 24018

View details

$15 SF/Yr

1,550 SF

Downtown Roanoke Office Space

Professional office space in a beautifully restored historic building.

120 Day Ave SW, Roanoke, VA

View details

$12 SF/Yr

2,000 SF

Roanoke Office Space for Rent

Updated office space with hardwood floors and dedicated parking.

1524 Patrick Rd NE, Roanoke, VA

View details

$5 SF/Yr

25,050 SF

Warehouse and Office Space Available

25,050 SF warehouse and 7,500 SF office space for lease.

2240 Shenandoah Ave NW, Roanoke, VA 24017

View details

$12 SF/Yr

7,544 SF

Accessible Office Space Near Downtown

Office space with easy access and close to downtown Roanoke.

Roanoke, VA 24016

View details

$18 SF/Yr

306 SF

Downtown Roanoke Office Space Available

Historic building with professional office space in downtown Roanoke.

304 Market St SE, Roanoke, VA

View details

$20 SF/Yr

853 SF

Professional Office at McVitty Center

853 SF office condo in well-established professional park.

2758 Electric Rd, Roanoke, VA

View details

$14 SF/Yr

875 SF

North Roanoke Plaza Retail/Office Space

Retail and office spaces available in North Roanoke Plaza.

3100 Peters Creek Rd, Roanoke, VA

View details

$12 SF/Yr

10,923 SF

Prime Commercial Space in Roanoke

Modern, versatile office space in Roanoke's Innovation Corridor.

2727 Franklin Rd, Roanoke, VA

View details

$12 SF/Yr

2,000 SF

Renovated Office Space in Roanoke

Turnkey office space with modern updates and convenient location.

1524 Patrick Rd NE, Roanoke, VA 24012

View details

$14 SF/Yr

91,500 SF

Refreshed Office Space Available

Modern office space in Roanoke's revitalized central business district.

34 Campbell Ave SW, Roanoke, VA 24011

View details

$16 SF/Yr

1,577 SF

Renovated Office Space Available

Newly renovated office space with flexible layout and great location.

4728 Starkey Rd, Roanoke, VA

View details

Contact for pricing

4,700 SF

Premier Office Space For Lease

Modern, renovated office space with excellent visibility and easy access.

5363 Peters Creek Rd NW, Roanoke, VA 24019

View details

$15 SF/Yr

6,150 SF

Premium Office Space Available

Premium office space for lease in Roanoke Valley.

5251 S Concourse Dr, Roanoke, VA

View details

$12 SF/Yr

Office Space Off Interstate

Office leasing opportunity with convenient access just off 581 for a range of professional uses.

1125 South Jefferson St., Roanoke, VA 24016

View details

$10 SF/Yr

Downtown Roanoke Office Space Available

Office space for lease in downtown Roanoke with garage.

25 Franklin Road, Roanoke, VA 24011

View details

$16 SF/Yr

1,152 SF

Roanoke Office and Medical Space

Office and medical space in Roanoke's growth corridor.

1315 2nd St SW, Roanoke, VA

View details

$14 SF/Yr

Adaptable Downtown Commercial Space

Versatile commercial building with office and garage space downtown.

202 2nd St NE, Roanoke, VA 24016

View details

$15 SF/Yr

1,267 SF

Renovated Office Space Near Airport

Turn-key office space with modern features and easy access.

5238 Valleypointe Pkwy, Roanoke, VA

View details

$7 SF/Yr

4,700 SF

Flex/Office Space Available

12,800 SF flex/office space with insulated room.

5205 Starkey Rd, Roanoke, VA

View details

Roanoke, VA Office Units Leasing Opportunities Market Analysis

Explore Office Units leasing options in Roanoke, VA with 76 listings featured on our commercial real estate exchange. The current inventory includes 396,128 square feet of properties with an estimated lease value of $1,111 /Mo.

Estimated lease rates for Office Units in Roanoke, VA begin at $1.95 SF/Yr, with an average of $18 SF/Yr and extend to $229 SF/Yr.

Register to start using Rey