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    Roanoke, VA Office Spaces for Lease

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    Vinton, VA Salem, VA Hollins, VA
    86 results
    Spacious Open Floorplan Office Space
    $3 SF/Yr
    18,200 SF
    Spacious Open Floorplan Office Space

    3441 Brandon Ave SW, Roanoke, VA 24018

    Large office space with flexible layout on Brandon Avenue.
    • High‑traffic location on Brandon Ave, ideal for businesses serving Southwest County, Downtown Roanoke, and surrounding areas.
    • Large ±18,200 sf space with a mostly open floorplan.
    • Flexible space that can be demised to fit various business needs.
    • Multiple bathrooms.
    • Owner willing to discuss tenant improvements at an adjusted lease rate.
    Updated: Mar 6
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    Brambleton Avenue Commercial Space Available
    $22 SF/Yr
    1,700 SF
    Brambleton Avenue Commercial Space Available

    5002 Brambleton Ave, Roanoke, VA 24018

    1,700 SF space suitable for medical, office, or retail.
    • High‑traffic location on Brambleton Ave with 26,000 vehicles per day
    • Versatile 1,700 SF space suitable for medical, professional office, or retail use
    • Previously a dental office, featuring 4 operatories, reception area, 2 bathrooms, office, sterilization area, and break room
    • Close proximity to the new Publix site and established neighborhoods
    • Located in a desirable area of southwest county
    Updated: Mar 6
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    Downtown Roanoke Office or Retail
    $10 SF/Yr
    2,600 SF
    Downtown Roanoke Office or Retail

    Office or retail space in downtown Roanoke.

    9 Franklin Rd SW, Roanoke, VA 24011

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    Retail/Office Space on Brambleton Ave
    $12 SF/Yr
    7,260 SF
    Retail/Office Space on Brambleton Ave

    Well-maintained retail/office space with excellent road visibility.

    Roanoke, VA 24018

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    Downtown Roanoke Office Space
    $15 SF/Yr
    1,550 SF
    Downtown Roanoke Office Space

    Professional office space in a beautifully restored historic building.

    120 Day Ave SW, Roanoke, VA

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    Roanoke Office Space for Rent
    $12 SF/Yr
    2,000 SF
    Roanoke Office Space for Rent

    Updated office space with hardwood floors and dedicated parking.

    1524 Patrick Rd NE, Roanoke, VA

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    Warehouse and Office Space Available
    $5 SF/Yr
    25,050 SF
    Warehouse and Office Space Available

    25,050 SF warehouse and 7,500 SF office space for lease.

    2240 Shenandoah Ave NW, Roanoke, VA 24017

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    Accessible Office Space Near Downtown
    $12 SF/Yr
    7,544 SF
    Accessible Office Space Near Downtown

    Office space with easy access and close to downtown Roanoke.

    Roanoke, VA 24016

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    Downtown Roanoke Office Space Available
    $18 SF/Yr
    306 SF
    Downtown Roanoke Office Space Available

    Historic building with professional office space in downtown Roanoke.

    304 Market St SE, Roanoke, VA

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    Professional Office at McVitty Center
    $20 SF/Yr
    853 SF
    Professional Office at McVitty Center

    853 SF office condo in well-established professional park.

    2758 Electric Rd, Roanoke, VA

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    North Roanoke Plaza Retail/Office Space
    $14 SF/Yr
    875 SF
    North Roanoke Plaza Retail/Office Space

    Retail and office spaces available in North Roanoke Plaza.

    3100 Peters Creek Rd, Roanoke, VA

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    Prime Commercial Space in Roanoke
    $12 SF/Yr
    10,923 SF
    Prime Commercial Space in Roanoke

    Modern, versatile office space in Roanoke's Innovation Corridor.

    2727 Franklin Rd, Roanoke, VA

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    Renovated Office Space in Roanoke
    $12 SF/Yr
    2,000 SF
    Renovated Office Space in Roanoke

    Turnkey office space with modern updates and convenient location.

    1524 Patrick Rd NE, Roanoke, VA 24012

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    Retail Space Near Valley View
    Contact for pricing
    6,900 SF
    Retail Space Near Valley View

    Endcap space for sale or lease near Valley View Mall.

    1920 Valley View Blvd NW, Roanoke, VA 24012

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    Refreshed Office Space Available
    $14 SF/Yr
    91,500 SF
    Refreshed Office Space Available

    Modern office space in Roanoke's revitalized central business district.

    34 Campbell Ave SW, Roanoke, VA 24011

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    Renovated Office Space Available
    $16 SF/Yr
    1,577 SF
    Renovated Office Space Available

    Newly renovated office space with flexible layout and great location.

    4728 Starkey Rd, Roanoke, VA

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    Premier Office Space For Lease
    Contact for pricing
    4,700 SF
    Premier Office Space For Lease

    Modern, renovated office space with excellent visibility and easy access.

    5363 Peters Creek Rd NW, Roanoke, VA 24019

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    Premium Office Space Available
    $15 SF/Yr
    6,150 SF
    Premium Office Space Available

    Premium office space for lease in Roanoke Valley.

    5251 S Concourse Dr, Roanoke, VA

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    Valley Court Business Center Office
    Contact for pricing
    74,000 SF
    Valley Court Business Center Office

    74,000 SF office space in Roanoke's Airport District.

    3601 Thirlane Road Northwest, Roanoke, VA 24012

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    Downtown Roanoke Office Space Available
    $10 SF/Yr
    Downtown Roanoke Office Space Available

    Office space for lease in downtown Roanoke with garage.

    25 Franklin Road, Roanoke, VA 24011

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    Modern Office Building Near Interstate
    Contact for pricing
    72,000 SF
    Modern Office Building Near Interstate

    Three-story office building with flexible suite sizes and ample parking.

    1745 Loch Haven Drive, Roanoke, VA 24019

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    Roanoke Office and Medical Space
    $16 SF/Yr
    1,152 SF
    Roanoke Office and Medical Space

    Office and medical space in Roanoke's growth corridor.

    1315 2nd St SW, Roanoke, VA

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    Adaptable Downtown Commercial Space
    $14 SF/Yr
    Adaptable Downtown Commercial Space

    Versatile commercial building with office and garage space downtown.

    202 2nd St NE, Roanoke, VA 24016

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    Renovated Office Space Near Airport
    $15 SF/Yr
    1,267 SF
    Renovated Office Space Near Airport

    Turn-key office space with modern features and easy access.

    5238 Valleypointe Pkwy, Roanoke, VA

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    Roanoke, VA Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Roanoke, VA with 86 listings featured on our commercial real estate exchange. The current inventory includes 568,536 square feet of properties with an estimated lease value of $1,236 /Mo.

    Estimated lease rates for Office Spaces in Roanoke, VA begin at $1.95 SF/Yr, with an average of $17 SF/Yr and extend to $229 SF/Yr.
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