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    Roanoke, VA
    Mixed-Use

    Roanoke, VA Mixed-use Properties for Sale

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    Vinton, VA Salem, VA Cave Spring, VA Hollins, VA Hardy, VA Cloverdale, VA Boones Mill, VA Troutville, VA
    15 properties
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    Updated Mixed-Use Building
    Updated: May 28
    Updated Mixed-Use Building

    4310 Brandon Ave SW, Roanoke, VA 24018

    $299,999
    0.59 AC lot
    C‑2‑zoned mixed‑use property with retail, office, or studio use potential
    0.59‑acre site at 4310 Brandon Ave SW, Roanoke, VA 24018
    Recent roof, water heater, A/C heat pump, and flooring updates
    Full bathroom and storage area within the building
    Concrete construction with marble flooring
    View details
    Two-Unit Mixed-Use Building
    Updated: Nov 13, 2025
    Two-Unit Mixed-Use Building

    22 Campbell Ave SE, Roanoke, VA 24011

    $799,000
    0.05 AC lot
    4,400 SF two‑unit building with retail and residential components
    Second‑floor 2bd/2bth residence renovated in 2021
    Glass‑front street‑level retail space
    1902 brick construction with full sprinkler system and freight elevator
    D‑Downtown zoning on a 0.05‑acre lot
    View details
    Mixed-Use Property with Multiple Structures
    Mixed-Use Property with Multiple Structures

    5851&5877 Cloverdale Rd, Roanoke, VA 24019

    $650,000
    2.30 AC lot

    Two commercial buildings and a house are offered in their existing condition on a 2.3-acre property.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Seven-Story Office Building
    Seven-Story Office Building

    30 - 38 Church Ave, Roanoke, VA 24011

    $3,200,000
    48,638 sqft

    Downtown office property with large floor plates, two passenger elevators, and Opportunity Zone Downtown zoning.

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    Mixed-Use Retail and Office Building
    Mixed-Use Retail and Office Building

    2302 Winthrop Ave Sw, Roanoke, VA 24015

    $495,000
    1,964 sqft

    One-story, handicap-accessible mixed-use building with 2 bathrooms, new roof, and a tankless water heater.

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    Roanoke Executive Park Investment Opportunity
    Roanoke Executive Park Investment Opportunity

    5306 Peters Creek Rd, Roanoke, VA 24019

    Contact for pricing
    54,000 sqft 5.10 AC lot

    Six-building commercial campus with flexible zoning and high visibility.

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    Mixed-Use Property with Corner Land
    Mixed-Use Property with Corner Land

    3312 Cove Rd Nw, Roanoke, VA 24017

    $850,000

    Multi-tenant improvements and an adjoining parcel accommodate current occupancy, expansion, or redevelopment plans.

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    Historic Mixed-Use Property
    Historic Mixed-Use Property

    1307 Maple Ave SW, Roanoke, VA 24016

    Contact for pricing
    2,268 sqft

    MX-zoned property supporting residential, commercial, or combined live-work use in Roanoke’s Old Southwest area.

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    Mixed-Use Building with Medical Offices
    Mixed-Use Building with Medical Offices

    1602 Grandin Rd Sw, Roanoke, VA 24015

    $549,000
    3,013 sqft

    CN-zoned property combines professional workspace with a separately accessed residential unit.

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    Mixed-Use Building with Leased Units
    Mixed-Use Building with Leased Units

    1011 2nd St Sw, Roanoke, VA 24016

    $415,000
    3,294 sqft

    Mixed-use building with office space and two leased apartments.

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    Mixed-Use Building with Lower-Level Space
    Mixed-Use Building with Lower-Level Space

    3646 Brambleton Ave SW, Roanoke, VA 24015

    Contact for pricing

    Two-level commercial layout with restrooms, finished support areas, and parking on both sides of the building.

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    Prime Commercial Development Opportunity
    Prime Commercial Development Opportunity

    4402 Old Rocky Mt Rd, Roanoke, VA 24014

    Contact for pricing
    4.36 AC lot

    4.36 acres of mixed-use land for commercial development.

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    Mixed-Use Retail/Office Condo
    Mixed-Use Retail/Office Condo

    5325 Peters Creek Road, Roanoke, VA 24019

    Contact for pricing

    Commercial condominium unit with display windows, a large sales floor, and access suited to office or retail occupancy.

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    Green Ridge Center For Sale
    Green Ridge Center For Sale

    2350 Peters Crk Rd NW, Roanoke, VA 24017

    Contact for pricing
    13,908 sqft

    Mixed-use property with retail and office spaces available for sale.

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    Mixed-Use Building with Event Space
    Mixed-Use Building with Event Space

    929 Murray Ave SE, Roanoke, VA 24013

    Contact for pricing

    Lower-level banquet space accommodates seating for up to 400 people.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 15 Active listings in Roanoke, VA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 57 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Corner Building
    Mixed-Use Corner Building

    628 S Colorado St, Salem, VA 24153

    Contact for pricing
    1,316 sqft

    Versatile corner property with flexible interior rooms, porch entry, and ample parking plus a detached garage with utilities.

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    Mixed-Use Building with Restaurant
    Mixed-Use Building with Restaurant

    130 Scruggs Rd, Moneta, VA 24121

    Contact for pricing
    9,600 sqft

    Restaurant, office, and storage uses are arranged across three levels with dedicated office amenities.

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    Mixed-Use Retail and Office Building
    Mixed-Use Retail and Office Building

    1650 Scruggs Rd, Moneta, VA 24121

    Contact for pricing
    3,400 sqft 0.94 AC lot

    B2-zoned commercial property combining retail and office uses.

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    Mixed-Use Corner Property
    Mixed-Use Corner Property

    901 S Colorado St, Salem, VA 24153

    $475,000

    Two completely remodeled commercial buildings offer retail/office space and fully leased residential units on a corner lot.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Mixed-Use Development Lot
    Mixed-Use Development Lot

    Church Ave SE, Roanoke, VA 24013

    Contact for pricing
    0.11 AC lot

    Small lot with water and sewer availability for flexible mixed-use development in Roanoke.

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    Commercial Land with VDOT-Approved Entrance
    Commercial Land with VDOT-Approved Entrance

    Booker T Washington Hwy lot: 3, Hardy, VA 24101

    $2,200,000
    7.75 AC lot

    7.75 acres with a VDOT-approved entrance off Route 122, paved access, and water available at the site.

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    PCD Zoned Lakewatch Commercial Pads
    PCD Zoned Lakewatch Commercial Pads

    LOT C-26 Booker T. Washington Highway, Moneta, VA 24121

    $225,000
    1.37 AC lot

    Zoned PCD for planned commercial development with 54 graded commercial pads served by water and gravity sewer.

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    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    15093 A Moneta Rd, Moneta, VA 24121

    $2,499,000
    56.00 AC lot

    56-acre tract with mixed-use zoning potential and utilities available, offering strong exposure along Route 122.

    View details

    Off-Market Properties in Roanoke, VA

    Consider similar Off-Market properties in Roanoke, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3042 Brambleton SW Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    3042 Brambleton SW Ave, Roanoke, VA 24015-4404

    $540,000
    Estimated value
    1,648 sqft 0.50 AC lot
    View details
    1515 11th NE St
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    1515 11th NE St, Roanoke, VA 24012-5811

    $485,000
    Estimated value
    17,457 sqft 2.79 AC lot
    View details
    1518 Hershberger NW Rd
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    1518 Hershberger NW Rd, Roanoke, VA 24012-7320

    $1,200,000
    Estimated value
    2,506 sqft 0.54 AC lot
    View details
    2311 Colonial SW Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    2311 Colonial SW Ave, Roanoke, VA 24015-3103

    $315,000
    Estimated value
    1,235 sqft 0.15 AC lot
    View details
    3607 Williamson NW Rd
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    3607 Williamson NW Rd, Roanoke, VA 24012-3327

    $390,000
    Estimated value
    13,431 sqft 0.64 AC lot
    View details
    1617 9th SE St
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    1617 9th SE St, Roanoke, VA 24013-2711

    $140,000
    Estimated value
    1,479 sqft 0.12 AC lot
    View details
    3348 Salem NW Tpke
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    3348 Salem NW Tpke, Roanoke, VA 24017-6607

    $3,520,000
    Estimated value
    27,177 sqft 6.67 AC lot
    View details
    3026 Wentworth NW Ave
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    3026 Wentworth NW Ave, Roanoke, VA 24012-3440

    $335,000
    Estimated value
    5,318 sqft 0.33 AC lot
    View details
    4840 Lanford NW St
    MIXED USE (COMMERCIAL/INDUSTRIAL)

    4840 Lanford NW St, Roanoke, VA 24012-2345

    $405,000
    Estimated value
    8,800 sqft 1.04 AC lot
    View details

    Roanoke, VA Mixed-Use Properties Market Trends and Statistics

    Explore 72 mixed-use properties for sale in Roanoke, VA, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 127,085 square feet of properties for sale, with an estimated market value of $7,257,999.

    Sale prices for multi use buildings in Roanoke, VA start at $299,999, averaging $907,249, and reaching up to $3,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Live-work space 4

    Demographics Overview

    Population 171K
    Population Growth (5Y) +9.4%
    Median Household Income $66,063
    College Educated 10.0%

    High-Yield Neighborhoods for Investment

    Identify Roanoke submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    24015 $495K
    24011 $799K

    Taxes & Financing

    Tax Rate (average for all types) 1.05%
    Property Tax per SF $16.57 per SF
    Average Loan-to-Value 65.0%

    Property Size Breakdown

    The majority of commercial real estate listings in Roanoke fall within the 100,000+ square foot range.

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    Most Searched ZIP Codes in Roanoke, VA

    • 24015
    • 24017
    • 24019
    • 24011
    • 24014
    • 24016
    • 24018

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