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    Roanoke, VA Mixed-use Properties for Sale

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    Richmond, VA Fredericksburg, VA Winchester, VA
    13 results
    Versatile Retail and Industrial Property
    $329,000
    0.19 Acres

    Versatile Retail and Industrial Property

    1408 Williamson Rd NE, Roanoke, VA 24012

    Retail and industrial space in high-traffic Roanoke location.

    • High‑visibility, high‑traffic location on Williamson Rd.
    • Versatile property suitable for retail and industrial use.
    • 3,579 square feet of rentable space.
    • Includes a 1,238 square feet retail area currently set up as a hair salon.
    • 2,341 square feet industrial/storage component.
    Updated: Oct 17, 2025
    View details
    Updated Mixed-Use Building with High-End Finishes
    $2,100,000
    0.05 Acres

    Updated Mixed-Use Building with High-End Finishes

    109 Campbell Ave SW, Roanoke, VA 24011

    Extensively updated mixed-use building with high-end finishes and great views.

    • Extensively updated with extremely high‑end materials and great views, move‑in ready.
    • Two residential units, each with two bedrooms, Wolf gas stove, Cove dishwasher, and Sub‑Zero fridge.
    • Complete renovation including windows, flooring, HVAC, electrical, and plumbing.
    • Entry level suitable for art gallery with full‑size kitchen and plywood walls for easy artwork display.
    • Custom made cabinetry throughout.
    Updated: Jan 5
    View details
    Historic Horton Building Mixed-Use Property
    $2,875,000
    0.20 Acres

    Historic Horton Building Mixed-Use Property

    Mixed-use property in downtown Roanoke with residential and commercial spaces.

    302 1st St SW, Roanoke, VA 24011
    View details
    Historic Horton Building Mixed-Use Property
    $2,875,000
    0.20 Acres

    Historic Horton Building Mixed-Use Property

    Mixed-use property with residential lofts and commercial spaces in Roanoke.

    302 1st St SW, Roanoke, VA 24011
    View details
    Downtown Roanoke Mixed-Use Building
    $799,000
    0.05 Acres

    Downtown Roanoke Mixed-Use Building

    Two-unit building with retail space and modern residence.

    22 Campbell Ave SE, Roanoke, VA 24011
    View details
    Downtown Roanoke Mixed-Use Investment
    $650,000
    4,299 SF

    Downtown Roanoke Mixed-Use Investment

    Mixed-use property in downtown Roanoke with value-add potential.

    23 Salem Ave SE, Roanoke, VA 24011
    View details
    Peters Creek Road Commercial Property
    $1,300,000
    14,600 SF

    Peters Creek Road Commercial Property

    Commercial property with visibility and access on 1.27 acres.

    3783 Peters Creek Rd, Roanoke, VA 24018
    View details
    Roanoke Executive Park Investment Opportunity
    $7,325,000
    54,000 SF

    Roanoke Executive Park Investment Opportunity

    Six-building commercial campus with flexible zoning and high visibility.

    5306 Peters Creek Rd, Roanoke, VA 24019
    View details
    Mixed-Use Building with Leased Units
    $415,000
    3,294 SF

    Mixed-Use Building with Leased Units

    Mixed-use building with office space and two leased apartments.

    1011 2nd St SW, Roanoke, VA 24016
    View details
    Downtown Roanoke Mixed-Use Opportunity
    $349,950
    4,474 SF

    Downtown Roanoke Mixed-Use Opportunity

    Former florist building with live-work potential in downtown Roanoke.

    21 Church Ave SW, Roanoke, VA
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    Prime Commercial Development Opportunity
    $980,000

    Prime Commercial Development Opportunity

    4.36 acres of mixed-use land for commercial development.

    4402 Old Rocky Mt Rd, Roanoke, VA 24014
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    Green Ridge Center For Sale
    $1,649,000
    13,908 SF

    Green Ridge Center For Sale

    Mixed-use property with retail and office spaces available for sale.

    2350 Peters Crk Rd NW, Roanoke, VA 24017
    View details
    Land with Development Potential
    $550,000

    Land with Development Potential

    Land with frontage on US 220 and Clearbrook Lane.

    5403 Clearbrook Lane, Roanoke, VA 24014
    View details
    Based on your search, we've compiled 2716 Potential Opportunities for your consideration. Besides 13 Active listings in Roanoke, VA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2695 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Rocky Mount GB Zoned Property
    $324,900
    0.57 Acres

    Rocky Mount GB Zoned Property

    Well-maintained Rocky Mount property with detached workshop and garage.

    45 Meadow View Ave, Rocky Mount, VA 24151
    View details
    Historic Bedford Mixed-Use Storefronts
    $875,000

    Historic Bedford Mixed-Use Storefronts

    Prime investment in Bedford's downtown with retail, office, and warehouse potential.

    114 N Bridge St, Bedford, VA 24523
    View details
    Versatile Mixed-Use Building For Sale
    $3,450,000
    77,550 SF

    Versatile Mixed-Use Building For Sale

    77,550 SF mixed-use building with warehouse, retail, and office space.

    1045 N Main St, Rocky Mount, VA 24151
    View details
    Bedford Commercial Center For Sale
    $799,495
    7,516 SF

    Bedford Commercial Center For Sale

    Two-building commercial center with expansion potential in Bedford, Virginia.

    800 & 810 Blue Ridge Ave, Bedford, VA 24523
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Roanoke, VA Land Opportunity
    Contact for pricing
    0.11 Acres

    Roanoke, VA Land Opportunity

    Premium lot near downtown Roanoke with water and sewer access.

    Church Ave SE, Roanoke, VA 24013
    View details
    Prime Land For Development
    $999,900

    Prime Land For Development

    Level to rolling landscape suitable for commercial development.

    1 Moneta Road, Moneta, VA 24121
    View details
    Prime Land For Development
    $529,900

    Prime Land For Development

    Level to rolling landscape suitable for commercial development.

    1 Moneta Road, Moneta, VA 24121
    View details
    Commercial Land in Christiansburg, VA
    $799,000
    2.20 Acres

    Commercial Land in Christiansburg, VA

    2.15 acres of commercial land with development potential.

    0 Lucas Street NE, Christiansburg, VA 24073
    View details

    Explore Off-Market Properties in Roanoke, VA

    Consider similar Off-Market properties in Roanoke, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3042 Brambleton SW Ave

    3042 Brambleton SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,648 SF
    Value Estimation
    $535,000
    3042 Brambleton SW Ave, Roanoke, VA 24015-4404
    View details
    1515 11th NE St

    1515 11th NE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 17,457 SF
    Value Estimation
    $870,000
    1515 11th NE St, Roanoke, VA 24012-5811
    View details
    1518 Hershberger NW Rd

    1518 Hershberger NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,506 SF
    Value Estimation
    $1,165,000
    1518 Hershberger NW Rd, Roanoke, VA 24012-7320
    View details
    2311 Colonial SW Ave

    2311 Colonial SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,235 SF
    Value Estimation by Request
    2311 Colonial SW Ave, Roanoke, VA 24015-3103
    View details
    3607 Williamson NW Rd

    3607 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 13,431 SF
    Value Estimation
    $985,000
    3607 Williamson NW Rd, Roanoke, VA 24012-3327
    View details
    1617 9th SE St

    1617 9th SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,479 SF
    Value Estimation by Request
    1617 9th SE St, Roanoke, VA 24013-2711
    View details
    3348 Salem NW Tpke

    3348 Salem NW Tpke

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 27,177 SF
    Value Estimation
    $3,520,000
    3348 Salem NW Tpke, Roanoke, VA 24017-6607
    View details
    3026 Wentworth NW Ave

    3026 Wentworth NW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,318 SF
    Value Estimation by Request
    3026 Wentworth NW Ave, Roanoke, VA 24012-3440
    View details
    4840 Lanford NW St

    4840 Lanford NW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 8,800 SF
    Value Estimation
    $1,275,000
    4840 Lanford NW St, Roanoke, VA 24012-2345
    View details
    913 9th SE St

    913 9th SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,796 SF
    Value Estimation by Request
    913 9th SE St, Roanoke, VA 24013-1813
    View details
    1824 Williamson NE Rd

    1824 Williamson NE Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 33,824 SF
    Value Estimation by Request
    1824 Williamson NE Rd, Roanoke, VA 24012-5228
    View details

    Roanoke, VA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2708 mixed-use properties for sale in Roanoke, VA, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 76,933,020 square feet of properties for sale, with an estimated market value of $1,108,228,000.

    Sale prices for multi use buildings in Roanoke, VA start at $50,000, averaging $639,854, and reaching up to $12,815,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Roanoke, VA

    • 24011
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    • 24012
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