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Monroe County, NY Commercial Real Estate for Lease

559 results
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Fairport Office/Medical/Mixed Use Space
$16 SF/Yr
13,031 SF

Fairport Office/Medical/Mixed Use Space

4400 Nine Mile Point Rd, Fairport, NY 14450

Second floor office/medical space available for lease in Fairport, NY.

  • Versatile space suitable for office, medical, or mixed‑use purposes.
  • Convenient location with ample parking and easy access.
  • Located in front of Eagle Vale Golf Course, offering high visibility and potential customer traffic.
  • Well‑equipped 2nd‑floor space featuring a reception area, 15 private offices, 2 bathrooms, and storage rooms.
  • Available for immediate lease.
Updated: Jul 15, 2025
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Creative Studio Loft on Monroe
$1,350 / Mo
500 SF

Creative Studio Loft on Monroe

190 Monroe Ave, Rochester, NY 14607

500 SF creative space with utilities included on Monroe.

  • All utilities included in rent.
  • 500 sq ft studio loft featuring expansive windows and flexible space.
  • Located in a building with a vibrant community of creatives, boutique retail, and private offices.
  • Brand‑new HVAC and newly installed common areas.
  • Convenient parking options: paid parking next door (starting at $2/hour) and free street parking.
Updated: Oct 3, 2025
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Penfield Commercial Greenhouse & Cultivation Site
$825,000
3,200 SF

Penfield Commercial Greenhouse & Cultivation Site

12.88-acre commercial greenhouse and cultivation site with 25,000 SF greenhouse.

1345 Penfield Center Rd, Penfield, NY 14526
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Turnkey Liquor Retail Business
$150,000
1,980 SF

Turnkey Liquor Retail Business

Turnkey liquor retail business in Spencerport, NY for rent.

5324 W Rdg Ste B Rd, Spencerport, NY 14559
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Established Meat Market Business Opportunity
$375,000
3,220 SF

Established Meat Market Business Opportunity

Thriving meat market business for sale in Rochester, NY.

584-600 Hudson Ave, Rochester, NY 14605
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Office Condo with Flexible Space
$375,000
3,485 SF

Office Condo with Flexible Space

Office condo with extensive parking and flexible interior spaces.

101 Assembly Dr, Mendon, NY 14506
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Brighton Office Suite for Lease
$15 SF/Yr
2,400 SF

Brighton Office Suite for Lease

2,400 SF office suite in desirable Brighton commercial corridor.

37 Allens Creek Rd, Rochester, NY 14618
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Freestanding Building in Emerging District
$1.00 SF/Yr
2,916 SF

Freestanding Building in Emerging District

High-visibility 2,916 SF building in Rochester's active retail corridor.

266-270 Monroe Ave, Rochester, NY 14607
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Rochester Retail/Office Space Available
$2,400 / Mo
8,297 SF

Rochester Retail/Office Space Available

Retail/office space on East Henrietta Road with high traffic.

1475 E Henrietta Rd, Rochester, NY 14623
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Rochester Office Space For Rent
$900 / Mo
288 SF

Rochester Office Space For Rent

Office space near George Eastman House with parking included.

167 Atlantic Ave, Rochester, NY 14607
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Versatile Commercial Space in Rochester
$4,500 / Mo
6,000 SF

Versatile Commercial Space in Rochester

6,000 sq ft space ideal for restaurant or bar.

123 Liberty Pole Way, Rochester, NY 14604
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East Rochester Commercial Space Available
$2,500 / Mo
800 SF

East Rochester Commercial Space Available

Open space suitable for daycare, fitness, tutoring, or gatherings.

115 Main St, East Rochester, NY 14445
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Rochester Commercial Property Sublease Opportunity
$11 SF/Yr
4,626 SF

Rochester Commercial Property Sublease Opportunity

Commercial property in Rochester, NY, available as a sublease.

801-807 S Plymouth Ave, Rochester, NY 14608
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Updated Office Space Available
$1,000 / Mo
13,670 SF

Updated Office Space Available

Handicap accessible office space with flexible options in central location.

233 Alexander St, Rochester, NY 14607
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Fairport Retail Space For Rent
$15 SF/Yr
38,195 SF

Fairport Retail Space For Rent

Retail spaces available in successful Town Centre Plaza, Fairport, NY.

7374 Pittsford Palmyra Rd, Fairport, NY 14450
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Pittsford Village Office Suite
$13 SF/Yr
1,222 SF

Pittsford Village Office Suite

Versatile office space in Pittsford Village Green Office Park.

59 Monroe Ave, Pittsford, NY 14534
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Prime Downtown Rochester Commercial Space
$14 SF/Yr
39,831 SF

Prime Downtown Rochester Commercial Space

Build-to-suit opportunity in the heart of Downtown Rochester.

49 Stone St, Rochester, NY 14604
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Mendon Retail Property For Rent
$699,900
8,266 SF

Mendon Retail Property For Rent

Retail property in Mendon, NY, with 8,266 square feet.

1369 Pittsford Mendon Rd, Mendon, NY 14506
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Stone Gate Office Complex Suites
$10 SF/Yr
20,781 SF

Stone Gate Office Complex Suites

Flexible office spaces available in a well-maintained Rochester complex.

2005 Lyell Ave, Rochester, NY 14606
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Versatile Office Building in Rochester
$590,000
8,320 SF

Versatile Office Building in Rochester

8320 sq ft office building with flexible leasing options.

1171 Titus Avenue Ext, Rochester, NY 14617
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Versatile Commercial Space Near Arcadia High
$535,000
4,362 SF

Versatile Commercial Space Near Arcadia High

Adaptable commercial building suitable for medical, office, or childcare uses.

353 Island Cottage Rd, Rochester, NY 14612
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Office Space in Webster, NY
$18 SF/Yr
24,996 SF

Office Space in Webster, NY

Office space available in a mixed-use building with ample parking.

1695 Empire Blvd, Webster, NY 14580
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Spacious Apartment Near Cobbs Hill
$2,100 / Mo

Spacious Apartment Near Cobbs Hill

Three-bedroom apartment near Cobbs Hill Park with updated features.

15-17 Roosevelt St, Rochester, NY 14607
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Pittsford Village Office Space
$1,500 / Mo
1,375 SF

Pittsford Village Office Space

1375 SF office space in the heart of Pittsford Village.

16-20 S Main St, Pittsford, NY 14534
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Monroe County, NY Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Monroe County, NY with 825 listings featured on our commercial real estate exchange. The current inventory includes 298,774,685,880 square feet of properties with an estimated lease value of $138,340.

Estimated lease rates for Commercial Real Estate in Monroe County, NY begin at $0.88 SF/Yr, with an average of $604 /Mo and extend to $120,000.

In Monroe County, NY, current lease rates show:

  • Office Properties & Spaces positioned at $119
  • Office space measuring $146
  • Retail properties assessed at $1,447
  • Industrial properties calculated at $9
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