Penfield, NY Commercial real estate for Rent & Lease

NY, East Rochester - Commercial Street

333 Commercial St, Unit 3RD, East Rochester, NY 14445

$129-$12,032/Mo

11 sqft

(972) 764-8885

Flexible workspace in NY, East Rochester - Commercial Street. Book a tour & get info

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NY, Rochester - Monroe Ave

3300 Rochester, Rochester, NY 14618

$129-$17,042/Mo

11 sqft

(972) 764-8885

Flexible workspace in NY, Rochester - Monroe Ave. Book a tour & get info

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Updated: May 7, 2025

Penfield Commercial Greenhouse & Cultivation Site

1345 Penfield Center Road, Penfield, NY 14526

$825,000 SF/Yr

3,200 sqft · $220,000,000/Mo

12.88‑acre Penfield, NY parcel with 25,000 SF greenhouse for cultivation and growing operations
Includes 1 acre hydroponic greenhouse plus 3,200 SF commercial space
800‑amp updated electric service; heating includes electric and natural gas with forced air and zoned systems
Central air and zoned cooling with separate meters
3 walk‑in coolers within the commercial space; replacement greenhouse plastic for roofs included

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Updated: Nov 24, 2025

Penfield Office Space Available

441 Penbrooke Dr, Penfield, NY

$19 SF/Yr

880 sqft · $1,415/Mo

Convenient location in Penfield, close to Routes 250 and 441, providing easy access to Fairport and Webster.
Move‑in ready space available starting September 1st.
Proximity to essential amenities: Wegman's and Target shopping plazas within 1/2 mile.
Variety of dining options within 1/2 mile: Jeremiah's, Panera Bread, and Monte Alban.
Close to schools, daycare options, and the local YMCA.

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Penfield Office Space Available

421 Penbrooke Dr, Penfield, NY

$19 SF/Yr

693 sqft · $1,114/Mo

Office space for rent in Penfield, move-in ready.

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Redeveloped Retail Space in Penfield

2200 Penfield Rd, Penfield, NY 14526

$24 SF/Yr

Retail, restaurant, and medical office spaces available in Penfield.

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Functional Commercial Suite on Penfield

2025 Penfield Rd, Penfield, NY

$15 SF/Yr

1,400 sqft · $1,750/Mo

Well-maintained 1,400 SF commercial suite on Penfield Road.

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Commercial Lot in Penfield

1600 Penfield Rd, Penfield, NY 14625

$500,000 SF/Yr

Undeveloped commercial lot in a high-traffic area.

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Retail Spaces in Penfield, NY

1657 Frpt Nine Mile Pt Rd, Penfield, NY 14526

$15 SF/Yr

Ground floor retail spaces in new multi-family development.

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Prime Retail Center for Lease

2150 Fairport Nine Mile Point Rd, Penfield, NY 14526

Contact for pricing

Multi-tenant retail center at a high-traffic intersection in Penfield.

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Penfield Office Space Available

481 Penbrooke Dr, Penfield, NY

$20 SF/Yr

1,922 sqft · $3,211/Mo

Office space for rent in Penfield, move-in ready.

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Arbors at Penfield Retail Spaces

200 Peaceful Pond Way, Penfield, NY 14526

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3,737 sqft

Ground floor retail/office spaces in Penfield, New York.

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Two-Acre Development Site Available

3286 Atlantic Ave, Penfield, NY

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Two-acre development site with high visibility and traffic counts.

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Retail Space on Penfield Road

2200 Penfield Rd, Penfield, NY

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1,200 sqft

Retail space with updated facade and high traffic volume.

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Prime Land Lease Opportunity

2240 Penfield Rd, Penfield, NY

$6,658/Mo

1.62-acre lot for retail, office, mixed-use, or residential development.

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5.1 Acres Commercial Land Available

2195 Penfield Rd, Penfield, NY

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Two parcels totaling 5.1 acres for lease or build-to-suit.

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5.35 Acre Pad Site

100 Parker Hl Dr, Penfield, NY 14625

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5.35-acre pad site for lease in Penfield, NY.

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Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 17 Active listings in Penfield, NY, we suggest exploring alternatives. Similar 5 Properties for Sales.

Similar Spaces for Sale in Penfield, NY

Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

Land Parcel at Signalized Intersection

2499 Browncroft Blvd, Penfield, NY 14625

$250,000

0.88 AC lot

Land parcel suitable for office or restaurant with drive-through.

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Panera Bread Investment Opportunity

9 Mile Point Rd E, Penfield, NY

$2,875,000

4,334 sqft · 1.21 AC lot

Property leased to Panera Bread in prime location.

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Prime Commercial Land in Penfield

1798 Penfield Rd, Penfield, NY

$750,000

0.66 AC lot

High-visibility 0.66-acre lot in Penfield's four corners district.

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Fairport Retail Property For Sale

2146 Fairport Nine Mile Pt Rd, Penfield, NY

$3,083,000

3,500 sqft · 1.39 AC lot

Retail property with a new 20-year lease in Penfield, NY.

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Penfield Commercial Greenhouse and Cultivation

1345 Penfield Center Rd, Penfield, NY 14526

$824,999

25,000 sqft · 12.88 AC lot

12.88-acre site with greenhouse, commercial space, and apartments.

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