Lancaster County, SC Office buildings for sale

Updated: Dec 1, 2025

Two-Building Professional Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

Two professional buildings on one property: 1201 and 1203 Colonial Commons Ct
1201 Colonial Commons Ct set up as a medical office with ~14 rooms, reception, waiting room, and wired for an X‑ray room
1203 Colonial Commons Ct includes reception and waiting room areas, file room, three curtained areas, large open space, and upper‑level work stations
PO (Professional Office) zoning per the City of Lancaster zoning chart
Building 1 received new flooring and a new roof

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Updated: Jun 11

Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

$575,000

29,151 sqft

1930s‑vintage commercial buildings in downtown Lancaster, SC, historically used for retail or office space
Currently vacant and in need of renovation—space offers a value‑add rehabilitation opportunity
Off Highway 521 and about 5 minutes from the Highway 9 intersection
Within 10 miles: population of over 56,000 grew 10% since 2020, with a forecast to grow an additional 16% by 2029
More than $641 million in consumer spending during 2024 within 10 miles

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Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

$760,000

22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

$575,000

29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Downtown Mixed-Use Building for Renovation

229 S. Main Street, Lancaster, SC 29720

$275,000

15,266 sqft

Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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Versatile Commercial Building in Lancaster

302 N White St, Lancaster, SC 29720

$325,000

Two-story commercial building with offices in downtown Lancaster, SC.

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Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 6 Active listings in Lancaster County, SC, we suggest exploring several alternatives: plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land in Lancaster, SC

2836 Lynwood Drive, Lancaster, SC 29720

$149,900

0.47 AC lot

Commercial land suitable for various business ventures.

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Rock Hill Commercial Land Available

2164 Eden Terrace, Rock Hill, SC 29730

$350,000

3.64 AC lot

3.64 acre commercial land parcel in Rock Hill, SC.

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Commercial Lot in Rock Hill

2135 Eden Terrace, Rock Hill, SC 29730

$450,000

1.08 AC lot

Commercial land for sale, suitable for development or owner financing.

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Monroe Commercial Land For Sale

Charles Hunley Lane, Monroe, NC 28112

$1,700,000

7.62 AC lot

Commercial land available in high-traffic Monroe location.

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Lancaster County, SC Office Buildings Market Trends and Statistics

Explore 6 office buildings for sale in Lancaster County, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 96,112 square feet of properties for sale, with an estimated market value of $2,185,000.

Sale prices for office properties in Lancaster County, SC start at $275,000, averaging $546,250, and reaching up to $760,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.