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    Lancaster County, SC Office Buildings for Sale

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    Columbia, SC Hilton Head Island, SC Greenville, SC Myrtle Beach, SC Spartanburg, SC Aiken, SC Anderson, SC Lexington, SC
    10 properties
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    Commercial Land with Office Building
    Updated: Sep 8
    Commercial Land with Office Building

    731 S Market Street, Lancaster, SC 29720

    $140,000
    1.62 AC lot
    1.62‑acre commercial parcel
    B3 General Business zoning
    Existing office building positioned along the edge of the lot
    Approximately 270 feet of frontage on S Market Street
    Public water and sewer on site
    View details
    Medical Office Building
    Updated: May 4
    Medical Office Building

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1.76 AC lot
    More than 1,100 square feet of building area
    1.76‑acre property comprising two lots
    Previously used as a dental office
    Electric heating and air conditioning
    Zoned KER; built in 1965
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    Two-Building Office Property
    Two-Building Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot

    One building is configured for medical office use, while the other includes open space and upper-level workstations.

    View details
    Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
    Historic Mixed-Use Retail/Office Buildings
    Historic Mixed-Use Retail/Office Buildings

    209-227 S. Main Street, Lancaster, SC 29720

    Contact for pricing
    29,151 sqft

    Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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    Downtown Mixed-Use Redevelopment Property
    Downtown Mixed-Use Redevelopment Property

    210 S. White Street, Lancaster, SC 29720

    Contact for pricing
    22,251 sqft

    Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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    Office Building
    Office Building

    312 N Main Street N, Lancaster, SC 29720

    Contact for pricing
    2,706 sqft

    Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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    1930s Retail/Office Building Portfolio
    1930s Retail/Office Building Portfolio

    116 Arch Street, Lancaster, SC 29720

    Contact for pricing
    29,444 sqft

    Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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    Versatile Commercial Building in Lancaster
    Versatile Commercial Building in Lancaster

    302 N White St, Lancaster, SC 29720

    $325,000

    Two-story commercial building with offices in downtown Lancaster, SC.

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    Office Building with Live-Work Use
    Office Building with Live-Work Use

    36-305 E Arch St, Lancaster, SC 29720

    $250,000

    B-2 zoning supports residential occupancy alongside a business, with parking and accessible entry.

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    Commercial Land with Office Building
    Commercial Land with Office Building

    731 S Market St, Lancaster, SC 29720

    $140,000

    B3-zoned parcel with an existing office building and city utilities on site.

    View details
    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 10 Active listings in Lancaster County, SC, we suggest exploring several alternatives: plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Brick Storefront Property
    Brick Storefront Property

    2836 Lynwood Drive, Lancaster, SC 29720

    $149,900
    0.47 AC lot

    Commercial space with central air, electric heat, carpet flooring, and a bathroom.

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    Commercial Land with Dual Frontage
    Commercial Land with Dual Frontage

    2164 Eden Terrace, Rock Hill, SC 29730

    $350,000
    3.64 AC lot

    GC-zoned development site with public sewer and access from two road frontages.

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    O-I Zoned Commercial Land
    O-I Zoned Commercial Land

    2135 Eden Terrace, Rock Hill, SC 29730

    $450,000
    1.08 AC lot

    The parcel is zoned O-I and has public sewer service for commercial land planning.

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    Medical Office Development Land
    Medical Office Development Land

    Charles Hunley Lane, Monroe, NC 28112

    $1,700,000
    7.62 AC lot

    Commercial land within a medical and office park, positioned near major highways, healthcare services, restaurants, and businesses.

    View details

    Lancaster County, SC Office Buildings Market Trends and Statistics

    Explore 10 office buildings for sale in Lancaster County, SC, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 83,552 square feet of properties for sale, with an estimated market value of $2,030,000.

    Sale prices for commercial office buildings in Lancaster County, SC start at $140,000, averaging $338,333, and reaching up to $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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