Advertise
    South Carolina
    Mixed-Use

    Charleston County, SC Mixed-use Properties for Lease

    Notify Me
    List
    Map
    Myrtle Beach, SC Greenville, SC Columbia, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Murrells Inlet, SC
    11 properties
    Sort:
    Mixed-Use Development on Highway 41
    Updated: Mar 27
    Mixed-Use Development on Highway 41

    1031 & 1039 Hwy 41, Mount Pleasant, SC 29466

    $28 SF/Yr
    16,000 sqft
    High traffic location: Situated at the intersection of Hwy 17 and Hwy 41, with a combined 79,500 vehicles per day.
    Large 16,000 sq ft multi‑building mixed‑use development.
    Ideal for retail and office space.
    Located next to CVS and Seels Outboard.
    Benefits from the growing residential population of nearby developments (Rivertowne, Dunes West, Park West, Charleston National).
    View details
    Office Units with Flexible Sizes
    Updated: Jul 16
    Office Units with Flexible Sizes

    61 Broad St, Charleston, SC 29401

    Contact for pricing
    1,230 sqft
    1,230 - 4,498 SF of office space available for lease
    Office units located at 61 Broad St, Charleston, SC 29401
    Third- and fourth‑floor residential units have independent access via a separate staircase
    A few nearby parking spaces may be leased separately on a monthly basis
    View details
    Ground-Floor Mixed-Use Suite
    Ground-Floor Mixed-Use Suite

    284 Meeting Street # 101, Charleston, SC 29401

    Silver Hill/Magnolia
    Contact for pricing
    1,600 sqft

    An open interior with HVAC and two restrooms supports office or retail use.

    Two restrooms  HVAC  Beautiful mahogany storefront
    View details
    Mixed-Use Retail and Entertainment Center
    Mixed-Use Retail and Entertainment Center

    1740 Towne Centre Way, Mount Pleasant, SC 29464

    Contact for pricing
    Multi-tenant  3,713 sqft
    Highway access  Road access

    Towne Centre offers retail and dining alongside Regal Cinemas, Belk, and Hyatt Place.

    View details
    Ground-Floor Mixed-Use Suite
    Ground-Floor Mixed-Use Suite

    284 Meeting Street, Charleston, SC 29401

    Silver Hill/Magnolia
    Contact for pricing
    1,600 sqft

    Open-plan space includes two restrooms, HVAC, and a mahogany storefront.

    Two restrooms  HVAC  Mahogany storefront
    View details
    Mixed-Use Shopping Center Space
    Mixed-Use Shopping Center Space

    966 Houston Northcutt Blvd, Mt Pleasant, SC 29464

    Contact for pricing
    2,750 sqft
    Road access

    Commercial space within a center serving retail, office, and hotel uses.

    View details
    Second-Floor Office Suite
    Second-Floor Office Suite

    2000 Sam Rittenberg Boulevard Ste 3002, Charleston, SC 29407

    Contact for pricing
    8–14 people  2,237 sqft  Floor 2
    Highway access

    A 2,237-square-foot office suite is set within a center that combines office space and first-floor retail.

    View details
    Adaptive Reuse Mixed-Use Campus
    Adaptive Reuse Mixed-Use Campus

    1501 King Street, Charleston, SC 29405

    Silver Hill/Magnolia
    Contact for pricing
    2,227 sqft

    A mixed-use campus blending historic warehouse architecture with modern design, with curated outdoor courtyards and gathering areas.

    Lush courtyards  Outdoor gathering areas
    View details
    Three-Space Mixed-Use Property
    Three-Space Mixed-Use Property

    695 Meeting Street, Charleston, SC 29403

    Silver Hill/Magnolia
    Contact for pricing
    Multi-tenant

    Lease offering combines retail and office space with customer parking at a walkable Charleston location.

    Free customer on-site parking
    View details
    Adaptive Reuse Mixed-Use Property
    Adaptive Reuse Mixed-Use Property

    1501 King Street, Charleston, SC 29405

    Silver Hill/Magnolia
    Contact for pricing
    3,345 sqft  historic warehouse architecture

    Flexible commercial space within a campus combining food, retail, wellness, and office uses around landscaped courtyards.

    Courtyards  Outdoor gathering areas
    View details
    Mixed-Use Building with Retail
    Mixed-Use Building with Retail

    68 1/2 Lee Street, Charleston, SC 29403

    East Side
    Contact for pricing

    New construction combines retail space below with an office suite on the upper floor.

    Primary and direct visual signage
    View details
    11 active listings match your search: Mixed-Use for lease in Charleston County, SC. Based on your search, we've also compiled 15 Potential Opportunities for your consideration: 15 properties for sale.

    Similar Spaces for Sale in Charleston County, SC

    Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

    Mixed-Use Office Property
    Mixed-Use Office Property

    565 Savannah Highway, Charleston, SC 29407

    $1,250,000
    3,018 sqft

    Flexible ground-floor layout with kitchen and mixed-use zoning for business and residential uses.

    View details
    Three-Story Mixed-Use Property
    Three-Story Mixed-Use Property

    651 King Street, Charleston, SC 29403

    $4,695,000
    4,253 sqft 0.05 AC lot

    Modern Charleston asset combining short-term lodging with leased commercial space and restaurant-ready infrastructure.

    View details
    Historic Mixed-Use Mansion
    Historic Mixed-Use Mansion

    20 S Battery Street, Charleston, SC 29401

    $16,500,000
    15,699 sqft

    Renovated Greek Revival property combining a private residence with an 11-room licensed inn.

    View details
    Navy Yard Redevelopment Opportunity
    Navy Yard Redevelopment Opportunity

    1975 N Hobson Ave, North Charleston, SC 29405

    $6,500,000
    50,000 sqft 1.95 AC lot

    Mixed-use redevelopment opportunity in North Charleston's Navy Yard.

    View details
    Mixed-Use Property with Restaurant Shell
    Mixed-Use Property with Restaurant Shell

    69 Columbus Street, Charleston, SC 29403

    Contact for pricing
    4,328 sqft

    Four-space mixed-use property combining barber, restaurant, and residential components.

    View details
    Mixed-Use Building with Apartment
    Mixed-Use Building with Apartment

    6209 Savannah Highway # B, Ravenel, SC 29470

    Contact for pricing
    5,342 sqft 0.87 AC lot

    Brick commercial space includes an upstairs three-bedroom apartment and is offered in its current condition.

    View details
    Three-Story Mixed-Use Property
    Three-Story Mixed-Use Property

    651 King St, Charleston, SC 29403

    $4,695,000
    4,253 sqft

    2024 construction pairs a leased commercial storefront with a five-bedroom short-term rental and rooftop terrace.

    View details
    3-Unit Mixed-Use Property with Restaurant
    3-Unit Mixed-Use Property with Restaurant

    162 Spring Street # C Unit: A, B, C, Charleston, SC 29403

    $2,500,000
    2,451 sqft

    Two furnished upstairs residences accompany a restaurant space leased on NNN terms.

    View details
    Mixed-Use Office Warehouse Portfolio
    Mixed-Use Office Warehouse Portfolio

    3129 West Montague Avenue, North Charleston, SC 29418

    Contact for pricing
    32,998 sqft

    The property combines office, warehouse, and flex-space components within one commercial portfolio.

    View details
    Three-Story Mixed-Use Building
    Three-Story Mixed-Use Building

    438 King St, Charleston, SC 29403

    Contact for pricing
    10,673 sqft

    Three-story mixed-use building with large storefront windows, on-site parking, and warm-shell renovation delivery.

    View details
    Mixed-Use Property with Medical Office
    Mixed-Use Property with Medical Office

    112 Rutledge Avenue, Charleston, SC 29401

    $2,795,000
    6,873 sqft

    Three upper-level apartments complement a street-level medical office and dedicated parking.

    View details
    Marshfront Mixed-Use Property
    Marshfront Mixed-Use Property

    2600 Savannah Hwy, Charleston, SC 29414

    Contact for pricing

    Commercial kitchen facilities, outdoor decks, and adaptable interior areas complement the marsh setting.

    View details
    Mixed-Use Property with Restaurant
    Mixed-Use Property with Restaurant

    162 Spring Street # D #A,B,C,D,E, Charleston, SC 29403

    Contact for pricing

    The assemblage combines short-term rental residences with a restaurant under an existing NNN lease.

    View details

    Charleston County, SC Mixed-use properties Market Trends and Statistics

    Explore Mixed-use properties leasing options in Charleston County, SC with 11 listings featured on our commercial real estate exchange. The current inventory includes 34,702 square feet of properties with an estimated lease value of $28.

    Estimated lease rates for Mixed-use properties in Charleston County, SC average $28 SF/Yr.
    List
    Map

    Mixed-use properties by market

    Browse Mixed-use properties for Lease Near Charleston, SC

    Popular Categories

    Featured Charleston County Real Estate Agencies

    Realmo connects you with licensed Charleston County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    AgentOwned Realty
    824 Johnnie Dodds Blvd Mount Pleasant, SC 29464
    Phone: (843) 572-0004
    AgentOwned.com
    Matt O'Neill Real Estate
    940 Johnnie Dodds Blvd., Suite 100 Mount Pleasant, SC 29464
    Phone: (843) 654-7777
    The Cassina Group
    309 Coleman Boulevard Mount Pleasant, SC 29464
    Phone: (843) 628-0008
    www.TheCassinaGroup.com
    Why this one?
    Saved

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!