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    Spartanburg, SC Mixed-use Properties for Lease

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    Historic Spartanburg Mixed-Use Retail Space
    Updated: Mar 26
    Historic Spartanburg Mixed-Use Retail Space

    174 E Main St, Spartanburg, SC 29306

    Contact for pricing
    4,709 sqft
    ±4,709 SF available on lower level**
    Historic building with early 20th‑century architectural character
    Upgraded to modern lifestyles
    45 Apartments
    High walkability and Main Street retail**
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    Spartanburg Flexible Space For Rent
    Updated: Oct 21, 2025
    Spartanburg Flexible Space For Rent

    1201 Union, Spartanburg, SC

    Contact for pricing
    34,053 sqft 4.14 AC lot
    ±34,000‑SF Flexible Space suitable for retail/mixed‑use.
    Direct access and street frontage on Union St.
    Located minutes from Downtown Spartanburg.
    Abundant parking.
    Adjacent concrete slab ideal for development.
    View details
    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 2 Active listings in Spartanburg, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

    Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Renovated Mixed-Use Property
    Renovated Mixed-Use Property

    219 Amboy Rd, Asheville, NC 28806

    $3,500/Mo
    4,535 sqft

    Flexible commercial space combines bar, restaurant, office, commissary kitchen, courtyard, patio, and onsite parking.

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    Lower-Level Storefront Suites
    Lower-Level Storefront Suites

    244 Short Coxe Ave Unit 130, Asheville, NC 28801

    $3,667/Mo

    Renovated commercial building with two available suites and on-site parking near downtown amenities.

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    Topgolf-Anchored Mixed-Use Property
    Topgolf-Anchored Mixed-Use Property

    315 Tanner Price Way, Greenville, SC 29615

    Contact for pricing
    15,000 sqft

    Zoned for restaurant, hotel, industrial, and entertainment uses along Pelham Road’s major retail corridor.

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    Mixed-Use Development
    Mixed-Use Development

    320 Falls St, Greenville, SC 29601

    Contact for pricing
    5,539 sqft

    Mixed-use downtown project with 241 apartment units, a 196-room AC hotel, and fully leased office space.

    View details

    Similar Spaces for Sale in Spartanburg, SC

    Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

    Mixed-Use Property with Detached ADU
    Mixed-Use Property with Detached ADU

    1586 Skylyn Drive, Spartanburg, SC 29307

    $535,000
    2,466 sqft 0.59 AC lot

    A brick ranch and separate accessory dwelling provide distinct layouts for residential use or approved commercial applications.

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    Commercial Kitchen Property with Basement
    Commercial Kitchen Property with Basement

    850 Falling Creek Road, Spartanburg, SC 29301

    $330,000
    1,879 sqft 0.53 AC lot

    Commercial property with an open meeting area, kitchen infrastructure, storage, and parking capacity on a half-acre lot.

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    Mixed-Use Commercial Building
    Mixed-Use Commercial Building

    180 John B White Sr Boulevard, Spartanburg, SC 29306

    $525,000
    0.23 AC lot

    Interior renovation is underway in a versatile commercial building with paved parking.

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    Mixed-Use Retail/Office Building
    Mixed-Use Retail/Office Building

    453 Union St, Spartanburg, SC 29306

    Contact for pricing
    2,170 sqft

    Flexible commercial space near the Mary Black Rail Trail and downtown Spartanburg.

    View details
    Rare Redevelopment Opportunity 7 Retail Properties
    Rare Redevelopment Opportunity 7 Retail Properties

    127-163 E Main St, Spartanburg, SC 29306

    $8,950,000
    8,256 sqft 0.19 AC lot

    7 Retail Properties Rare Downtown Spartanburg Development Opportunity

    View details
    Mixed-Use Specialty Facility
    Mixed-Use Specialty Facility

    501 Willis Rd, Spartanburg, SC 29301

    Contact for pricing
    61,289 sqft

    PR-zoned property suited to pickleball, tennis, or an activity center.

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    Mixed-Use Property With Renovated Buildings
    Mixed-Use Property With Renovated Buildings

    8861 Warren B Abernathy Highway, Spartanburg, SC 29301

    $799,000
    2.19 AC lot

    Renovated buildings, a separate shop, and public water create a flexible commercial property setting.

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    Historic Mixed-Use Property For Sale
    Historic Mixed-Use Property For Sale

    571 E Main St, Spartanburg, SC 29302

    Contact for pricing
    4,688 sqft 0.48 AC lot

    4,688 SF mixed-use property in Converse Heights neighborhood.

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    Land Near Wofford College Campus
    Land Near Wofford College Campus

    577 N CHURCH ST, Spartanburg, SC 29306

    Contact for pricing

    Mixed-use land for sale near downtown and Wofford College.

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    Prime Land on E. Main
    Prime Land on E. Main

    2700 E Main St, Spartanburg, SC 29307

    Contact for pricing
    10,000 sqft 7.76 AC lot

    7.76 acres on a busy commercial corridor, redevelopment opportunity.

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    Spartanburg Eastside Mixed-Use Development Opportunity
    Spartanburg Eastside Mixed-Use Development Opportunity

    2910 E Main St, Spartanburg, SC 29307

    Contact for pricing
    11.56 AC lot

    11.56 acres for mixed-use development in Spartanburg's Eastside.

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    Land, Mixed Use
    Land, Mixed Use

    2052 Southport Rd, Spartanburg, SC 29306

    Contact for pricing

    Mixed-use properties

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    Spartanburg, SC Mixed-use properties Lease Rates & Market Statistics

    Explore 2 Mixed-use properties for lease in Spartanburg, SC on Realmo, a commercial real estate exchange covering the Spartanburg area. The current inventory totals 38,762 square feet of properties.

    Spartanburg accounts for 67% of the 3 mixed-use properties currently available across Spartanburg County, where a nearby market includes Drayton.

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    Featured Spartanburg Real Estate Agencies

    Realmo connects you with licensed Spartanburg CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Keller Williams Realty Spartanburg Partners
    1707 John B White Sr Blvd, Suite E Spartanburg, SC 29301
    Phone: 18645746000
    www.kwspartanburg.com
    Better Homes and Gardens Young & Company
    8291 Warren H. Abernathy Highway Spartanburg, SC 29301
    Phone: 19706605323
    bhgyoung.com
    Agent Pros Realty
    2992 Reidville Rd Spartanburg, SC 29301
    Phone: 18645999907
    agentprosrealty.com
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