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    Spartanburg, SC Mixed-use Properties for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    Historic Mill Office Space Available
    $28 SF/Yr
    53,571 SF

    Historic Mill Office Space Available

    1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

    Creative office space in a vibrant mixed-use community.

    • Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
    • ±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.
    • Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
    • Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
    • Flexible space suitable for office, creative studio, co‑working, or boutique professional services.
    Updated: Nov 25, 2025
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    Spartanburg Flexible Space For Rent
    $8 SF/Yr
    34,053 SF

    Spartanburg Flexible Space For Rent

    1201 Union, Spartanburg, SC

    Flexible space suitable for retail or mixed-use purposes.

    • ±34,000‑SF Flexible Space suitable for retail/mixed‑use.
    • Direct access and street frontage on Union St.
    • Located minutes from Downtown Spartanburg.
    • Abundant parking.
    • Adjacent concrete slab ideal for development.
    Updated: Oct 21, 2025
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    1,800 SF Office Building
    $15 SF/Yr

    1,800 SF Office Building

    1,800 SF Office Building

    1971 S Pine St, Spartanburg, SC 29302
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    Historic Spartanburg Mixed-Use Retail Space
    Contact for pricing
    4,709 SF

    Historic Spartanburg Mixed-Use Retail Space

    Retail space available in historic mixed-use building in downtown Spartanburg.

    174 E Main St, Spartanburg, SC 29306
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    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 4 Active listings in Spartanburg, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

    Explore Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    New Mixed-Use Suites Available
    Contact for pricing
    1,262 SF

    New Mixed-Use Suites Available

    New commercial spaces for lease in mixed-use development.

    50 Tanner Rd, Greenville, SC 29607
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    4,200 SF Industrial Buildings
    $12 SF/Yr

    4,200 SF Industrial Buildings

    4,200 SF 2 Industrial Buildings

    474-A & 474-B Hampshire Drive, Gaffney, SC 29341
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    4,200 SF Industrial Buildings
    $12 SF/Yr

    4,200 SF Industrial Buildings

    4,200 SF 2 Industrial Buildings

    474-A & 474-B Hampshire Drive, Gaffney, SC 29341
    View details
    Downtown Greenville Mixed-Use Retail Space
    Contact for pricing
    5,874 SF

    Downtown Greenville Mixed-Use Retail Space

    Retail space available in downtown Greenville's West End.

    702 S Main St, Greenville, SC
    View details

    Explore Similar Spaces for Sale in Spartanburg, SC

    Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

    Versatile Commercial Property in Spartanburg
    $749,000
    2,900 SF

    Versatile Commercial Property in Spartanburg

    Functional space with expansion potential near Downtown Spartanburg.

    449 W Centennial Street, Spartanburg, SC 29303
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    Spartanburg Mixed-Use Investment Opportunity
    $325,000
    2,600 SF

    Spartanburg Mixed-Use Investment Opportunity

    Mixed-use property with income potential near Interstates 85 and 26.

    511 Broadcast Drive, Spartanburg, SC 29303
    View details
    Versatile Mixed-Use Spartanburg Property
    $110,000
    3,388 SF

    Versatile Mixed-Use Spartanburg Property

    3388 sq ft mixed-use property with conversion potential in Spartanburg.

    100 Clary Drive, Spartanburg, SC 29303
    View details
    Spartanburg Multi-Use Investment Opportunity
    $200,000
    0.71 Acres

    Spartanburg Multi-Use Investment Opportunity

    Investment property with tenants in place near Spartanburg city limits.

    170 S Blackstock Road, Spartanburg, SC 29301
    View details
    Downtown Spartanburg Mixed-Use Opportunity
    $1,500,000
    4,809 SF

    Downtown Spartanburg Mixed-Use Opportunity

    Historic downtown Spartanburg property with commercial and residential potential.

    139 West Main Street, Spartanburg, SC 29306
    View details
    Rare Redevelopment Opportunity 7 Retail Properties
    $8,950,000
    8,256 SF

    Rare Redevelopment Opportunity 7 Retail Properties

    7 Retail Properties Rare Downtown Spartanburg Development Opportunity

    127-163 E Main St, Spartanburg, SC 29306
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    Rare Redevelopment Opportunity 7 Retail Properties
    $8,950,000
    8,256 SF

    Rare Redevelopment Opportunity 7 Retail Properties

    7 Retail Properties Rare Downtown Spartanburg Development Opportunity

    127-163 E Main St, Spartanburg, SC 29306
    View details
    Mixed-Use Property in Spartanburg
    $200,000
    1,300 SF

    Mixed-Use Property in Spartanburg

    Investment opportunity with tenants in place near Spartanburg City Limits.

    170 S Blackstock Road, Spartanburg, SC 29301
    View details
    Highway Frontage Automotive/Industrial Opportunity
    $625,000
    4,300 SF

    Highway Frontage Automotive/Industrial Opportunity

    4,300 SF property on 3.82 acres near downtown Spartanburg.

    2940 S Pine St, Spartanburg, SC 29302
    View details
    Versatile Commercial Building Near Hospital
    $845,000
    11,925 SF

    Versatile Commercial Building Near Hospital

    Adaptable commercial building suitable for medical, retail, or storage use.

    200 Dillon Cir, Spartanburg, SC 29307
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    Historic Mixed-Use Property For Sale
    $1,275,000
    4,688 SF

    Historic Mixed-Use Property For Sale

    4,688 SF mixed-use property in Converse Heights neighborhood.

    571 E Main St, Spartanburg, SC 29302
    View details
    Prime Land on E. Main
    $1,975,000
    10,000 SF

    Prime Land on E. Main

    7.76 acres on a busy commercial corridor, redevelopment opportunity.

    2700 E Main St, Spartanburg, SC 29307
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Atlanta Land for Lease
    $1,850/Mo

    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315
    View details
    Prime Commercial Acres For Lease
    $6,000/Mo

    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986
    View details
    MidTown Corner Lot For Rent
    Contact for pricing

    MidTown Corner Lot For Rent

    Corner lot with high visibility in growing Nashville neighborhood.

    1811 Charlotte Avenue, Nashville, TN 37203
    View details
    Prime Commercial Land in Schenectady
    $23 SF/Yr
    22,240 SF

    Prime Commercial Land in Schenectady

    High-visibility commercial land suitable for retail, office, or mixed-use development.

    120 Erie Boulevard, Schenectady, NY 12305
    View details

    Spartanburg, SC Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Spartanburg, SC with 4 listings featured on our commercial real estate exchange. The current inventory includes 78,408,000 square feet of properties with an estimated lease value of $15 SF/Yr.

    Estimated lease rates for Mixed-use properties in Spartanburg, SC begin at $15 SF/Yr, with an average of $15 SF/Yr and extend to $15 SF/Yr.
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    Most Searched ZIP Codes in Spartanburg, SC

    • 29302
    • 29306
    • 29307

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