Spartanburg County, SC Mixed-use properties for Rent & Lease

$28 SF/Yr

53,571 SF

Historic Mill Office Space Available

1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

Creative office space in a vibrant mixed-use community.

Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.
Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
Flexible space suitable for office, creative studio, co‑working, or boutique professional services.

Updated: Nov 25, 2025

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$8 SF/Yr

34,053 SF

Spartanburg Flexible Space For Rent

1201 Union, Spartanburg, SC

Flexible space suitable for retail or mixed-use purposes.

±34,000‑SF Flexible Space suitable for retail/mixed‑use.
Direct access and street frontage on Union St.
Located minutes from Downtown Spartanburg.
Abundant parking.
Adjacent concrete slab ideal for development.

Updated: Oct 21, 2025

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Historic Spartanburg Mixed-Use Retail Space

$17 SF/Yr

4,709 SF

Historic Spartanburg Mixed-Use Retail Space

Retail space available in historic mixed-use building in downtown Spartanburg.

174 E Main St, Spartanburg, SC 29306

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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 3 Active listings in Spartanburg County, SC, we suggest exploring alternatives. Similar 13 Properties for Sales.

Similar Spaces for Sale in Spartanburg County, SC

Consider Similar Space for Sale. We found 13 Spaces matching your search parameters.

$1,350,000

7,500 SF

Inman Commercial Property For Sale

2.75 acre commercial property with 7,500 SF building.

1385 Meadow Farm Road, Inman, SC 29349

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$685,000

1,152 SF

Commercial Property in Booming Area

Redevelopment opportunity on a corner lot in Moore, SC.

5757 Reidville Rd, Moore, SC 29369

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Restaurant/Convenience Store with Living Area

$175,000

1,500 SF

Restaurant/Convenience Store with Living Area

Commercial restaurant/convenience store with living area in Cross Anchor, SC.

701 Union Highway, Cross Anchor, SC 29335

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$475,000

4,000 SF

Adaptable Commercial Space in Landrum

4,000 sq. ft. commercial space with office and warehouse.

146 N Trade Avenue, Landrum, SC 29356

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$2,300,000

5.00 Acres

Prime Investment Land Opportunity

Strategically located 5-acre plot in a rapidly growing area.

4819 Highway 101, Woodruff, SC 29388

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$4,000,000

Land Near Wofford College Campus

Mixed-use land for sale near downtown and Wofford College.

577 N CHURCH ST, Spartanburg, SC 29306

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Industrial Warehouse and Office Property

$3,475,000

40,875 SF

Industrial Warehouse and Office Property

4 buildings on 5.29 acres in Spartanburg County.

4139 S Church St Ext, Roebuck, SC 29376

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Rare Redevelopment Opportunity 7 Retail Properties

$8,950,000

8,256 SF

Rare Redevelopment Opportunity 7 Retail Properties

7 Retail Properties Rare Downtown Spartanburg Development Opportunity

127-163 E Main St, Spartanburg, SC 29306

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Highway Frontage Automotive/Industrial Opportunity

$625,000

4,300 SF

Highway Frontage Automotive/Industrial Opportunity

4,300 SF property on 3.82 acres near downtown Spartanburg.

2940 S Pine St, Spartanburg, SC 29302

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$1,275,000

4,688 SF

Historic Mixed-Use Property For Sale

4,688 SF mixed-use property in Converse Heights neighborhood.

571 E Main St, Spartanburg, SC 29302

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Versatile Commercial Building Near Hospital

$845,000

11,925 SF

Versatile Commercial Building Near Hospital

Adaptable commercial building suitable for medical, retail, or storage use.

200 Dillon Cir, Spartanburg, SC 29307

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$1,975,000

10,000 SF

Prime Land on E. Main

7.76 acres on a busy commercial corridor, redevelopment opportunity.

2700 E Main St, Spartanburg, SC 29307

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Landrum Commercial Building with Warehouse

$475,000

4,000 SF

Landrum Commercial Building with Warehouse

4,000 sq ft mixed-use building in Landrum, South Carolina.

146 S 562, Landrum, SC 29356

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$1,850/Mo

Atlanta Land for Lease

3-acre commercial land available for lease in Atlanta, GA.

1057 Constitution Road SW, Atlanta, GA 30315

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$6,000/Mo

Prime Commercial Acres For Lease

4.12 acres of commercial land for lease in Rainsville, AL.

4.12 Acres Al Highway 35, Rainsville, AL 35986

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Contact for pricing

MidTown Corner Lot For Rent

Corner lot with high visibility in growing Nashville neighborhood.

1811 Charlotte Avenue, Nashville, TN 37203

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Contact for pricing

Prime Land in Jarrettsville Corridor

1.55 acre parcel in Jarrettsville's business corridor.

1753, Jarrettsville, MD 21084

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Spartanburg County, SC Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in Spartanburg County, SC with 3 listings featured on our commercial real estate exchange. The current inventory includes 92,333 square feet of properties with an estimated lease value of $54 SF/Yr.

Estimated lease rates for Mixed-use properties in Spartanburg County, SC begin at $8 SF/Yr, with an average of $18 SF/Yr and extend to $28 SF/Yr.