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    Spartanburg County, SC Mixed-use Properties for Lease

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    Historic Mill Office Space Available
    Updated: Nov 25, 2025
    Historic Mill Office Space Available

    1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

    $16 SF/Yr
    53,571 sqft
    Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
    ±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.**
    Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
    Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
    Flexible space suitable for office, creative studio, co‑working, or boutique professional services.
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    Spartanburg Flexible Space For Rent
    Updated: Oct 21, 2025
    Spartanburg Flexible Space For Rent

    1201 Union, Spartanburg, SC

    Contact for pricing
    34,053 sqft 4.14 AC lot
    ±34,000‑SF Flexible Space suitable for retail/mixed‑use.
    Direct access and street frontage on Union St.
    Located minutes from Downtown Spartanburg.
    Abundant parking.
    Adjacent concrete slab ideal for development.
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    Mixed-Use Retail and Office Space
    Mixed-Use Retail and Office Space

    21 N Main St, Wellford, SC 29377

    Contact for pricing
    2,286 sqft

    Brand-new mixed-use facility offers pre-leasing with options for tenant customization within a redeveloped mill community.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Historic Mixed-Use Retail Suites
    Historic Mixed-Use Retail Suites

    5359-5369 N Main St, Cowpens, SC 29330

    Contact for pricing
    1,731 sqft

    Two retail spaces inside the historic Potter’s Old Store, with apartment units on the upper level, scheduled for completion in fall 2025.

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    Historic Spartanburg Mixed-Use Retail Space
    Historic Spartanburg Mixed-Use Retail Space

    174 E Main St, Spartanburg, SC 29306

    Contact for pricing
    4,709 sqft

    Retail space available in historic mixed-use building in downtown Spartanburg.

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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 5 Active listings in Spartanburg County, SC, we suggest exploring alternatives. Similar 9 Properties for Sales.

    Similar Spaces for Sale in Spartanburg County, SC

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Rare Redevelopment Opportunity 7 Retail Properties
    Rare Redevelopment Opportunity 7 Retail Properties

    127-163 E Main St, Spartanburg, SC 29306

    $8,950,000
    8,256 sqft 0.19 AC lot

    7 Retail Properties Rare Downtown Spartanburg Development Opportunity

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    Industrial Warehouse and Office Property
    Industrial Warehouse and Office Property

    4139 S Church St Ext, Roebuck, SC 29376

    Contact for pricing
    40,875 sqft 5.29 AC lot

    4 buildings on 5.29 acres in Spartanburg County.

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    Highway Frontage Automotive/Industrial Opportunity
    Highway Frontage Automotive/Industrial Opportunity

    2940 S Pine St, Spartanburg, SC 29302

    Contact for pricing
    4,300 sqft 3.82 AC lot

    4,300 SF property on 3.82 acres near downtown Spartanburg.

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    Upgraded Mixed-Use Building
    Upgraded Mixed-Use Building

    5286 S Main Street, Cowpens, SC 29330

    $195,000
    1,700 sqft

    Mixed-use building with a new roof and extensive electrical and plumbing upgrades throughout.

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    Historic Mixed-Use Property For Sale
    Historic Mixed-Use Property For Sale

    571 E Main St, Spartanburg, SC 29302

    Contact for pricing
    4,688 sqft 0.48 AC lot

    4,688 SF mixed-use property in Converse Heights neighborhood.

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    Land Near Wofford College Campus
    Land Near Wofford College Campus

    577 N CHURCH ST, Spartanburg, SC 29306

    Contact for pricing

    Mixed-use land for sale near downtown and Wofford College.

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    Prime Land on E. Main
    Prime Land on E. Main

    2700 E Main St, Spartanburg, SC 29307

    Contact for pricing
    10,000 sqft 7.76 AC lot

    7.76 acres on a busy commercial corridor, redevelopment opportunity.

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    Landrum Commercial Building with Warehouse
    Landrum Commercial Building with Warehouse

    146 S 562, Landrum, SC 29356

    Contact for pricing
    4,000 sqft

    4,000 sq ft mixed-use building in Landrum, South Carolina.

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    Spartanburg Eastside Mixed-Use Development Opportunity
    Spartanburg Eastside Mixed-Use Development Opportunity

    2910 E Main St, Spartanburg, SC 29307

    Contact for pricing
    11.56 AC lot

    11.56 acres for mixed-use development in Spartanburg's Eastside.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Agricultural Land Parcel
    Agricultural Land Parcel

    1057 Constitution Road SW, Atlanta, GA 30315

    $1,850/Mo

    Unimproved land with available water and electricity supports agricultural or compatible commercial use.

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    Commercial Land with Highway Access
    Commercial Land with Highway Access

    4.12 Acres Al Highway 35, Rainsville, AL 35986

    $6,000/Mo

    Prime commercial land on Highway 35 in Rainsville with an ALDOT-approved entrance and sewer available.

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    Prime Land in Jarrettsville Corridor
    Prime Land in Jarrettsville Corridor

    1753, Jarrettsville, MD 21084

    Contact for pricing
    1.55 AC lot

    1.55 acre parcel in Jarrettsville's business corridor.

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    Baton Rouge Commercial Parcel For Rent
    Baton Rouge Commercial Parcel For Rent

    7597 Jefferson Hwy, Baton Rouge, LA 70806

    Contact for pricing

    1.33-acre commercial parcel in a prime Baton Rouge location.

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    Spartanburg County, SC Mixed-use properties Market Trends and Statistics

    Explore Mixed-use properties leasing options in Spartanburg County, SC with 5 listings featured on our commercial real estate exchange. The current inventory includes 96,350 square feet of properties with an estimated lease value of $16 SF/Yr.

    Estimated lease rates for Mixed-use properties in Spartanburg County, SC average $16 SF/Yr.
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