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    Spartanburg County, SC Mixed-use Properties for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    Historic Mill Office Space Available
    $28 SF/Yr
    53,571 SF

    Historic Mill Office Space Available

    1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

    Creative office space in a vibrant mixed-use community.

    • Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
    • ±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.
    • Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
    • Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
    • Flexible space suitable for office, creative studio, co‑working, or boutique professional services.
    Updated: Nov 25, 2025
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    Spartanburg Flexible Space For Rent
    $8 SF/Yr
    34,053 SF

    Spartanburg Flexible Space For Rent

    1201 Union, Spartanburg, SC

    Flexible space suitable for retail or mixed-use purposes.

    • ±34,000‑SF Flexible Space suitable for retail/mixed‑use.
    • Direct access and street frontage on Union St.
    • Located minutes from Downtown Spartanburg.
    • Abundant parking.
    • Adjacent concrete slab ideal for development.
    Updated: Oct 21, 2025
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    1,800 SF Office Building
    $15 SF/Yr

    1,800 SF Office Building

    1,800 SF Office Building

    1971 S Pine St, Spartanburg, SC 29302
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    Historic Spartanburg Mixed-Use Retail Space
    Contact for pricing
    4,709 SF

    Historic Spartanburg Mixed-Use Retail Space

    Retail space available in historic mixed-use building in downtown Spartanburg.

    174 E Main St, Spartanburg, SC 29306
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    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 4 Active listings in Spartanburg County, SC, we suggest exploring alternatives. Similar 22 Properties for Sales.

    Similar Spaces for Sale in Spartanburg County, SC

    Consider Similar Space for Sale. We found 22 Spaces matching your search parameters.

    Versatile Commercial Property in Spartanburg
    $749,000
    2,900 SF

    Versatile Commercial Property in Spartanburg

    Functional space with expansion potential near Downtown Spartanburg.

    449 W Centennial Street, Spartanburg, SC 29303
    View details
    Landrum Commercial Property Near Trail
    $250,000
    1,131 SF

    Landrum Commercial Property Near Trail

    Mixed-use property near downtown and future Saluda Grade Rail Trail.

    111 W Crawford Street, Landrum, SC 29356
    View details
    Spartanburg Mixed-Use Investment Opportunity
    $325,000
    2,600 SF

    Spartanburg Mixed-Use Investment Opportunity

    Mixed-use property with income potential near Interstates 85 and 26.

    511 Broadcast Drive, Spartanburg, SC 29303
    View details
    Commercial Property in Booming Area
    $685,000
    1,152 SF

    Commercial Property in Booming Area

    Redevelopment opportunity on a corner lot in Moore, SC.

    5757 Reidville Rd, Moore, SC 29369
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    Restaurant/Convenience Store with Living Area
    $175,000
    1,500 SF

    Restaurant/Convenience Store with Living Area

    Commercial restaurant/convenience store with living area in Cross Anchor, SC.

    701 Union Highway, Cross Anchor, SC 29335
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    Versatile Mixed-Use Spartanburg Property
    $110,000
    3,388 SF

    Versatile Mixed-Use Spartanburg Property

    3388 sq ft mixed-use property with conversion potential in Spartanburg.

    100 Clary Drive, Spartanburg, SC 29303
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    Inman Commercial Property For Sale
    $1,350,000
    7,500 SF

    Inman Commercial Property For Sale

    2.75 acre commercial property with 7,500 SF building.

    1385 Meadow Farm Road, Inman, SC 29349
    View details
    Spartanburg Multi-Use Investment Opportunity
    $200,000
    0.71 Acres

    Spartanburg Multi-Use Investment Opportunity

    Investment property with tenants in place near Spartanburg city limits.

    170 S Blackstock Road, Spartanburg, SC 29301
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    Lyman Multi-Use Income Property
    $250,000
    2,200 SF

    Lyman Multi-Use Income Property

    Income-producing Lyman property with retail tenant and residential potential.

    54 Groce Road, Lyman, SC 29365
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    Downtown Spartanburg Mixed-Use Opportunity
    $1,500,000
    4,809 SF

    Downtown Spartanburg Mixed-Use Opportunity

    Historic downtown Spartanburg property with commercial and residential potential.

    139 West Main Street, Spartanburg, SC 29306
    View details
    Inman Multi-Use Commercial Property
    $273,000
    2,964 SF

    Inman Multi-Use Commercial Property

    Versatile commercial property with office space and residential apartment.

    1 Anderson Street Extension, Inman, SC 29349
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    Versatile Mixed-Use Property in Inman
    $273,000
    2,964 SF

    Versatile Mixed-Use Property in Inman

    Commercial property with office space and residential apartment in Inman.

    1 Anderson EXT Street, Inman, SC 29349
    View details
    Industrial Warehouse and Office Property
    $3,475,000
    40,875 SF

    Industrial Warehouse and Office Property

    4 buildings on 5.29 acres in Spartanburg County.

    4139 S Church St Ext, Roebuck, SC 29376
    View details
    Cowpens Mixed-Use Building For Sale
    $195,000
    1,700 SF

    Cowpens Mixed-Use Building For Sale

    Mixed-use building with recent upgrades in Cowpens, South Carolina.

    5286 S Main Street, Cowpens, SC 29330
    View details
    Rare Redevelopment Opportunity 7 Retail Properties
    $8,950,000
    8,256 SF

    Rare Redevelopment Opportunity 7 Retail Properties

    7 Retail Properties Rare Downtown Spartanburg Development Opportunity

    127-163 E Main St, Spartanburg, SC 29306
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    Rare Redevelopment Opportunity 7 Retail Properties
    $8,950,000
    8,256 SF

    Rare Redevelopment Opportunity 7 Retail Properties

    7 Retail Properties Rare Downtown Spartanburg Development Opportunity

    127-163 E Main St, Spartanburg, SC 29306
    View details
    Mixed-Use Property in Spartanburg
    $200,000
    1,300 SF

    Mixed-Use Property in Spartanburg

    Investment opportunity with tenants in place near Spartanburg City Limits.

    170 S Blackstock Road, Spartanburg, SC 29301
    View details
    Highway Frontage Automotive/Industrial Opportunity
    $625,000
    4,300 SF

    Highway Frontage Automotive/Industrial Opportunity

    4,300 SF property on 3.82 acres near downtown Spartanburg.

    2940 S Pine St, Spartanburg, SC 29302
    View details
    Versatile Commercial Building Near Hospital
    $845,000
    11,925 SF

    Versatile Commercial Building Near Hospital

    Adaptable commercial building suitable for medical, retail, or storage use.

    200 Dillon Cir, Spartanburg, SC 29307
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    Landrum Commercial Building with Warehouse
    $475,000
    4,000 SF

    Landrum Commercial Building with Warehouse

    4,000 sq ft mixed-use building in Landrum, South Carolina.

    146 S 562, Landrum, SC 29356
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Atlanta Land for Lease
    $1,850/Mo

    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315
    View details
    Prime Commercial Acres For Lease
    $6,000/Mo

    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986
    View details
    MidTown Corner Lot For Rent
    Contact for pricing

    MidTown Corner Lot For Rent

    Corner lot with high visibility in growing Nashville neighborhood.

    1811 Charlotte Avenue, Nashville, TN 37203
    View details
    Prime Land in Jarrettsville Corridor
    Contact for pricing

    Prime Land in Jarrettsville Corridor

    1.55 acre parcel in Jarrettsville's business corridor.

    1753, Jarrettsville, MD 21084
    View details

    Spartanburg County, SC Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Spartanburg County, SC with 4 listings featured on our commercial real estate exchange. The current inventory includes 87,624 square feet of properties with an estimated lease value of $36 SF/Yr.

    Estimated lease rates for Mixed-use properties in Spartanburg County, SC begin at $8 SF/Yr, with an average of $18 SF/Yr and extend to $28 SF/Yr.
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    Browse Mixed-use properties for Lease Near Spartanburg, SC

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