Horry County, SC Mixed-use properties for Rent & Lease

Updated: Sep 8

New Mixed-Use Space

5100 Highway 17 Bypass, Murrells Inlet, SC 29576

$3,125/Mo

2,500 sqft 1.90 AC lot

2,500 SF available within a 12,000 SF mixed‑use building
Can be configured as two 1,250 SF suites or one 2,500 SF space
Direct exposure on Highway 17 Bypass with approximately 36,700 vehicles per day
1.9‑acre site with ample parking
Projected completion March 2027

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Updated: Jul 13

Oceanfront End-Cap Retail Space

700 N Ocean Blvd, Myrtle Beach, SC 29577

$27 SF/Yr

4,251 sqft

4,251SF end‑cap retail unit
Oceanfront outdoor patio
Sidewalk connectivity to the Myrtle Beach Boardwalk
Located at the signalized intersection of 7th Ave N and North Ocean Blvd
Mixed‑use development completed in 2025

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Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 2 Active listings in Horry County, SC, we suggest exploring alternatives. Similar 21 Properties for Sales.

Similar Spaces for Sale in Horry County, SC

Consider Similar Space for Sale. We found 21 Spaces matching your search parameters.

Mixed-Use Property with Metal Buildings

4750 Hwy 17 S, Murrells Inlet, SC 29576

$4,399,000

4,000 sqft 6.24 AC lot

An approved conceptual plan outlines retail, warehouse, storage, and office uses.

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Renovated Mixed-Use Property

4378 Highway 17 Business, Murrells Inlet, SC 29576

$1,249,999

5,078 sqft 0.13 AC lot

Commercial property combines restaurant, retail, office, and residential configurations within a flexible multi-use layout.

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Two-Story Day Care Center

402 16th Ave. S, Myrtle Beach, SC 29577

$849,000

3,400 sqft 0.28 AC lot

MU-H zoning supports commercial and multifamily-oriented reuse, subject to applicable city requirements and approvals.

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Mixed-Use Property with Ice Cream Shop

612 S Ocean Blvd., Myrtle Beach, SC 29577

$1,250,000

2,910 sqft

Four-bedroom residential space is positioned above an equipped retail operation with the existing ice cream business included.

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Flex Industrial Building

200 Hucks Rd., Aynor, SC 29511

$1,800,000

5,000 sqft

Flexible commercial layout combines office functionality with warehouse space and roll-up loading access.

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Mixed-Use Property with Metal Buildings

4750 Hwy 17 S Unit 4583 Wesley RD, Murrells Inlet, SC 29576

$4,399,000

23,000 sqft 6.50 AC lot

PUD GC zoning and an approved conceptual plan support a combination of commercial uses.

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Two-Story Day Care Center

402 16th Ave. S, Myrtle Beach, SC 29577

$849,000

3,400 sqft

MU-H zoning supports consideration of several commercial and residential uses, subject to city requirements and approvals.

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Commercial Land with Existing Building

11091 Highway 707, Murrells Inlet, SC 29576

$1,700,000

2,200 sqft 3.61 AC lot

Zoned RE2 / CFA with an existing renovated brick structure, fenced yard, and outdoor storage.

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Mixed-Use Property with Offices

4123 Meeting St., Loris, SC 29569

$374,999

5,275 sqft 0.13 AC lot

Flexible commercial layout includes private offices, updated units, and infrastructure supporting food service build-out.

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Mixed-Use Property with Office/Garage

1560 G P Smith Ave., Longs, SC 29568

$599,000

1,800 sqft 1.03 AC lot

Includes a three-bay office and garage with a waiting area and bathroom, plus a refurbished residential unit.

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Mixed-Use Property with Insulated Buildings

4750 Hwy 17 S #4583 Wesley RD, 4583 Wesley RD, Murrells Inlet, SC 29576

$4,399,000

4,000 sqft 6.50 AC lot

An approved conceptual plan outlines additional building area and a mix of retail, warehouse, storage, or office uses.

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Mixed-Use Property with Gas Station

4580 W Highway 501, Conway, SC 29526

$3,000,000

3,104 sqft 1.13 AC lot

Commercially zoned site combines convenience retail, fueling, personal services, produce sales, and residential space.

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Downtown Mixed-Use Building

715 S Main St., Aynor, SC 29511

$2,100,000

18,500 sqft 0.69 AC lot

CBD-zoned property with on-site parking and shared commercial, religious, and retail occupancy.

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Oceanfront Mixed-Use Property

606 N Ocean Blvd., Myrtle Beach, SC 29577

$7,500,000

23,336 sqft 0.80 AC lot

Includes 54 units, an updated restaurant, and a separate parking parcel near Myrtle Beach’s Boardwalk.

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Mixed-Use Property with Showroom

1630 Hwy 17 S, Little River, SC 29566

$1,350,000

1.48 AC lot

The building combines office space, a large showroom, and warehouse area under Highway Commercial zoning.

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Corner Development Land with Curb Cut

1009 3rd Ave. N, Myrtle Beach, SC 29577

$225,000

0.80 AC lot

Corner lot zoned RMH and MU-M, positioned for high-visibility development with access via a 3rd Ave N curb cut.

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Gas Station With Mixed-Use Improvements

4580 W Highway 501, Conway, SC 29526

$3,000,000

1.13 AC lot

Gas station property with convenience retail, a barbershop, produce stand, and residential duplex.

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Mixed-Use Commercial Building

11935 Plaza Dr., Murrells Inlet, SC 29576

Contact for pricing

3,500 sqft

The interior can serve as one commercial space or be divided into two units.

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Mixed-Use Property with Theater Building

408 North Main Street, Conway, SC 29526

$2,400,000

Two downtown buildings combine Main Street frontage with a former theater property.

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Mixed-Use Property with Church

1300 N Kings Hwy., Myrtle Beach, SC 29577

$9,750,000

42,548 sqft 1.48 AC lot

A closed church building, vacant land, and paved parcels make up the property one block from the beach.

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Mixed-Use Property with Unfinished Interior

5002 Watergate Dr., Myrtle Beach, SC 29588

Contact for pricing

1,650 sqft

Interior walls are open to the studs, allowing plumbing and electrical work for a customized residential or commercial configuration.

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Horry County, SC Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in Horry County, SC with 2 listings featured on our commercial real estate exchange. The current inventory includes 6,751 square feet of properties with an estimated lease value of $42.

Estimated lease rates for Mixed-use properties in Horry County, SC begin at $15 SF/Yr, with an average of $21 SF/Yr and extend to $27 SF/Yr.

Featured Horry County Real Estate Agencies

Realmo connects you with licensed Horry County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Myrtle Beach

601 21st Ave North Myrtle Beach, SC 29577

Phone: 18434439400

www.KellerWilliamsMyrtleBeach.com

Elliott Coastal Living

401 Sea Mountain Highway North Myrtle Beach, SC 29582

Phone: 18432805704

www.elliottcoastalliving.com

Century 21 Thomas

625 Sea Mountain Highway North Myrtle Beach, SC 29582

Phone: 18432733001