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    Columbia, SC Mixed-use Properties for Lease

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    Cayce, SC West Columbia, SC Lexington, SC
    6 listings
    Updated Mixed-Use Commercial Space
    Contact for pricing
    2,201 SF
    Updated Mixed-Use Commercial Space

    746 Harden St., Columbia, SC 29205

    Updated mixed-use space with parking and high-speed internet in Columbia.
    • Prime location in the heart of Five Points on the corner of Harden and Greene Street.
    • Versatile mixed‑use commercial space with ± 1,932 SF of updated second‑floor space and 269 SF mezzanine storage.
    • Includes LED branded front signage overlooking Five Points fountain.
    • New Electric (Energy Star), HVAC with air purification, and Plumbing including Commercial Shower.
    • Two dedicated on‑site parking spots with EV level 2 charging capability.
    Updated: Jan 27
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    Historic Mixed-Use Building on Main
    Contact for pricing
    64,799 SF
    Historic Mixed-Use Building on Main

    1350 Main Street, Columbia, SC 29201

    Mixed-use building in Columbia's Central Business District.
    • Prime location in Columbia's Central Business District (CBD) on Main Street.
    • Walking distance to the State House, Courthouse, and the University of South Carolina.
    • Flexible floor plans & lease terms.
    • Landlord pays for up to three parking spaces in adjacent garage.
    • Full Service lease structure.
    Updated: Nov 26, 2025
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    Retail Space on Forest Drive
    Contact for pricing
    1,920 SF
    Retail Space on Forest Drive

    Retail space available in mixed-use development on Forest Drive.

    4609 Forest Dr, Columbia, SC

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    New Mixed-Use Building For Lease
    $33 SF/Yr
    14,660 SF
    New Mixed-Use Building For Lease

    New mixed-use building in thriving retail corridor available for lease.

    1514 Brentwood Dr, Columbia, SC 29206

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    Urban Redevelopment Mixed-Use Lifestyle District
    Contact for pricing
    Urban Redevelopment Mixed-Use Lifestyle District

    Vibrant mixed-use district in Columbia, SC, with commercial and residential spaces.

    2180 Pickens St, Columbia, SC 29201

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    Retail Space in BullStreet District
    Contact for pricing
    Retail Space in BullStreet District

    Vibrant retail space in Columbia's dynamic BullStreet District.

    2151 Pickens St, Columbia, SC 29201

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    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 6 Active listings in Columbia, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Turn-Key Office/Mixed-Use Space
    $1,100/Mo
    840 SF
    Turn-Key Office/Mixed-Use Space

    Move-in ready office or mixed-use space available on an NNN lease in downtown New Ellenton.

    413 Main Street S, New Ellenton, SC 29809

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    Build-Out Ready Office/Mixed-Use Space
    $800/Mo
    510 SF
    Build-Out Ready Office/Mixed-Use Space

    Build-out ready office and mixed-use space available on a NNN lease in New Ellenton.

    413 Main Street S, New Ellenton, SC 29809

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    Planned Mixed-Use Development Opportunity
    Contact for pricing
    Planned Mixed-Use Development Opportunity

    Mixed-use development opportunity at Chapin Road and Primrose Lane.

    565 Chapin Rd, Chapin, SC 29036

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    Planned Mixed-Use Development Opportunity
    Contact for pricing
    Planned Mixed-Use Development Opportunity

    Mixed-use development opportunity at Chapin Road and Primrose Lane.

    573 Chapin Rd, Chapin, SC 29036

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    Similar Spaces for Sale in Columbia, SC

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Versatile Commercial Opportunity in Columbia
    $550,000
    3,960 SF
    Versatile Commercial Opportunity in Columbia

    Prime commercial site with existing structure and redevelopment potential.

    123 Lawand Drive, Columbia, SC 29210

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    Office/Warehouse Space on Lake Murray
    $985,000
    5,384 SF
    Office/Warehouse Space on Lake Murray

    Functional office and warehouse space with convenient access to amenities.

    1682 Lake Murray Boulevard, Columbia, SC 29212

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    Mixed-Use Building on Large Lot
    $1,850,000
    9,261 SF
    Mixed-Use Building on Large Lot

    Freestanding mixed-use building with highway frontage and redevelopment potential.

    3905 Fernandina Rd, Columbia, SC 29210

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    Renovated Office and Living Space
    $925,000
    4,138 SF
    Renovated Office and Living Space

    Two-story building with flexible floorplan near Downtown Columbia.

    132 Stonemark Ln, Columbia, SC

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    Two Notch Road Commercial Property
    $239,000
    15,600 SF
    Two Notch Road Commercial Property

    Highly visible commercial property with flexible use opportunities.

    4949 Two Notch Rd, Columbia, SC 29204

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    Retail/Flex Building in Downtown
    Contact for pricing
    7,500 SF
    Retail/Flex Building in Downtown

    Multi-tenant building with retail, showroom, office, and warehouse space.

    300 Huger Street, Columbia, SC 29201

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    Downtown Columbia Redevelopment Opportunity
    Contact for pricing
    21,434 SF
    Downtown Columbia Redevelopment Opportunity

    One-acre redevelopment site at a prominent downtown intersection.

    1600 Bull Street, Columbia, SC 29201

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    Historic Building in The Vista
    $2,300,000
    12,170 SF
    Historic Building in The Vista

    Historic building with parking lot suitable for mixed-use development.

    925 Gervais St. & 1217 Park St, Columbia, SC 29201

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    Multifamily Conversion Opportunity
    $850,000
    20,000 SF
    Multifamily Conversion Opportunity

    Two-story buildings ideal for residential conversion in Columbia, SC.

    800 Dutch Square Blvd, Columbia, SC 29210

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Atlanta Land for Lease
    $1,850/Mo
    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315

    View details
    Prime Commercial Acres For Lease
    $6,000/Mo
    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986

    View details
    MidTown Corner Lot For Rent
    Contact for pricing
    MidTown Corner Lot For Rent

    Corner lot with high visibility in growing Nashville neighborhood.

    1811 Charlotte Avenue, Nashville, TN 37203

    View details
    Prime Land in Jarrettsville Corridor
    Contact for pricing
    Prime Land in Jarrettsville Corridor

    1.55 acre parcel in Jarrettsville's business corridor.

    1753, Jarrettsville, MD 21084

    View details

    Columbia, SC Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Columbia, SC with 6 listings featured on our commercial real estate exchange. The current inventory includes 14,660 square feet of properties with an estimated lease value of $33 SF/Yr.

    Estimated lease rates for Mixed-use properties in Columbia, SC begin at $33 SF/Yr, with an average of $33 SF/Yr and extend to $33 SF/Yr.
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    Most Searched ZIP Codes in Columbia, SC

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