Charleston, SC
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Charleston, SC Mixed-use Properties for Lease

    Notify Me
    List
    Map
    Wando, SC Mt Pleasant, SC North Charleston, SC
    Rivers Avenue Renovated Flex Space
    Contact for pricing
    4,420 SF

    Rivers Avenue Renovated Flex Space

    5640 Rivers Ave, Charleston, SC 29406

    Renovated flex space available on highly traveled retail strip.

    • Located on highly traveled Rivers Ave retail strip with excellent visibility.
    • Newly renovated office/retail/flex space.
    • Easy access to I‑26 and I‑526 (within 1/4 mile).
    • Suites can be leased individually or combined.
    • Suite options range from ±2,170 SF to ±4,420 SF.
    Updated: Mar 23
    View details
    Design-Forward Mixed-Use Campus Retail Space
    Contact for pricing
    4,238 SF

    Design-Forward Mixed-Use Campus Retail Space

    804 Meeting St, Charleston, SC

    Retail space available in Charleston's emerging NoMo district.

    • Located in Charleston's emerging North Morrison (NoMo) district.
    • Design‑forward mixed‑use campus.
    • Blend of retail, culinary, and creative office spaces.
    • Industrial‑modern architecture.
    • Walkable layout.
    Updated: Sep 15, 2025
    View details
    Charleston Mixed-Use Campus Retail Space
    Contact for pricing
    3,589 SF

    Charleston Mixed-Use Campus Retail Space

    Retail space in a design-forward mixed-use campus.

    141 Williams St, Charleston, SC
    View details
    Mixed-Use Development Retail Opportunity
    Contact for pricing

    Mixed-Use Development Retail Opportunity

    New mixed-use development offering retail space in Charleston's Medical District.

    102 President St, Charleston, SC 29403
    View details
    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 4 Active listings in Charleston, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    New Bluffton Flex and Retail
    Contact for pricing
    8,000 SF

    New Bluffton Flex and Retail

    New flex and retail buildings in the heart of Bluffton.

    5 Kitties Landing, Bluffton, SC 29910
    View details
    Class A Office Space
    Contact for pricing

    Class A Office Space

    Office space in mixed-use center with retail and residential.

    New Riverside Vlg Wy, Bluffton, SC 29910
    View details
    Mixed-Use Building in Downtown Nexton
    Contact for pricing
    20,000 SF

    Mixed-Use Building in Downtown Nexton

    Mixed-use building with apartments and commercial space in Summerville.

    Metropolitan Ave, Summerville, SC 29486
    View details
    Mixed-Use Concept in Nexton
    Contact for pricing

    Mixed-Use Concept in Nexton

    Walkable mixed-use concept with office, retail, and restaurant spaces.

    1227 - 1237 Nexton Parkway, Summerville, SC 29486
    View details

    Similar Spaces for Sale in Charleston, SC

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Historic Charleston Mixed-Use Building
    $2,650,000
    4,923 SF

    Historic Charleston Mixed-Use Building

    Three-story mixed-use building in Charleston's historic commercial corridor.

    59 Broad Street, Charleston, SC 29401
    View details
    Historic Charleston Mixed-Use Income Property
    $4,399,000
    4,252 SF

    Historic Charleston Mixed-Use Income Property

    Renovated mixed-use property in downtown Charleston with commercial and residential income.

    21 Broad Street, Charleston, SC 29401
    View details
    Renovated Mixed-Use Property For Sale
    $2,900,000
    4,500 SF

    Renovated Mixed-Use Property For Sale

    Two-story mixed-use property with retail and short-term rental units.

    200 Rutledge Ave, Charleston, SC 29403
    View details
    Rutledge Avenue Mixed-Use Building
    $2,975,000
    4,167 SF

    Rutledge Avenue Mixed-Use Building

    Mixed-use property with retail and residential units in Charleston.

    107 RUTLEDGE AVE, Charleston, SC
    View details
    Charleston Mixed-Use Investment Opportunity
    $8,490,000
    12,000 SF

    Charleston Mixed-Use Investment Opportunity

    Mixed-use property with retail and residential units in downtown Charleston.

    119 SPRING ST, Charleston, SC
    View details
    King Street Live/Work Loft
    $675,000
    840 SF

    King Street Live/Work Loft

    Unique live/work loft in the heart of downtown Charleston.

    487 King St, Charleston, SC 29403
    View details
    Charleston Warehouse with Redevelopment Potential
    $3,400,000
    8,911 SF

    Charleston Warehouse with Redevelopment Potential

    8,911 SF warehouse on 0.537 acres near Charleston Tech Center.

    60 Romney St, Charleston, SC 29403
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Atlanta Land for Lease
    $1,850/Mo

    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315
    View details
    Prime Commercial Acres For Lease
    $6,000/Mo

    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986
    View details
    MidTown Corner Lot For Rent
    Contact for pricing

    MidTown Corner Lot For Rent

    Corner lot with high visibility in growing Nashville neighborhood.

    1811 Charlotte Avenue, Nashville, TN 37203
    View details
    Prime Land in Jarrettsville Corridor
    Contact for pricing

    Prime Land in Jarrettsville Corridor

    1.55 acre parcel in Jarrettsville's business corridor.

    1753, Jarrettsville, MD 21084
    View details

    Charleston, SC Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Charleston, SC with 4 listings featured on our commercial real estate exchange. The current inventory includes 12,247 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Mixed-use properties in Charleston, SC begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
    List
    Map