South Carolina
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Lexington County, SC Mixed-use Properties for Lease

    Notify Me
    List
    Map
    Greenville, SC Columbia, SC Charleston, SC
    10 listings
    Mixed-Use Property in Cayce, SC
    $825/Mo
    7,541 SF
    Mixed-Use Property in Cayce, SC

    528-532 Knox Abbott Dr, Cayce, SC 29033

    Mixed-use property suitable for redevelopment, retail, or office use.
    • Excellent redevelopment, retail, or office opportunity with 8,100 sq ft of flexible space.
    • Prime location across the river from downtown Columbia, SC.
    • High visibility and easy access to I‑77 and I‑26.
    • Located in Cayce, a growing and diverse market.
    • Ideal for businesses seeking retail exposure or office space.
    Updated: Apr 15
    View details
    Class-A Mixed-Use Development For Rent
    Contact for pricing
    15,000 SF
    Class-A Mixed-Use Development For Rent

    351 Meeting Street, West Columbia, SC 29169

    New mixed-use development with commercial and residential spaces available for rent.
    • Unobstructed views of the river and Columbia skyline.
    • New Class‑A mixed‑use development with high‑end multi‑family apartment homes.
    • ±15,000 SF of commercial space suitable for office, retail, or restaurant use.
    • Pedestrian‑friendly access to the river, park amphitheater, local shopping, entertainment, and restaurants.
    • Ample parking with 400 total spaces, including a two‑level garage.
    Updated: Jan 27
    View details
    Updated Mixed-Use Commercial Space
    Contact for pricing
    2,201 SF
    Updated Mixed-Use Commercial Space

    Updated mixed-use space with parking and high-speed internet in Columbia.

    746 Harden St., Columbia, SC 29205

    View details
    Historic Mixed-Use Building on Main
    Contact for pricing
    64,799 SF
    Historic Mixed-Use Building on Main

    Mixed-use building in Columbia's Central Business District.

    1350 Main Street, Columbia, SC 29201

    View details
    Retail Space on Forest Drive
    Contact for pricing
    1,920 SF
    Retail Space on Forest Drive

    Retail space available in mixed-use development on Forest Drive.

    4609 Forest Dr, Columbia, SC

    View details
    Planned Mixed-Use Development Opportunity
    Contact for pricing
    Planned Mixed-Use Development Opportunity

    Mixed-use development opportunity at Chapin Road and Primrose Lane.

    565 Chapin Rd, Chapin, SC 29036

    View details
    Planned Mixed-Use Development Opportunity
    Contact for pricing
    Planned Mixed-Use Development Opportunity

    Mixed-use development opportunity at Chapin Road and Primrose Lane.

    573 Chapin Rd, Chapin, SC 29036

    View details
    New Mixed-Use Building For Lease
    $33 SF/Yr
    14,660 SF
    New Mixed-Use Building For Lease

    New mixed-use building in thriving retail corridor available for lease.

    1514 Brentwood Dr, Columbia, SC 29206

    View details
    Urban Redevelopment Mixed-Use Lifestyle District
    Contact for pricing
    Urban Redevelopment Mixed-Use Lifestyle District

    Vibrant mixed-use district in Columbia, SC, with commercial and residential spaces.

    2180 Pickens St, Columbia, SC 29201

    View details
    Retail Space in BullStreet District
    Contact for pricing
    Retail Space in BullStreet District

    Vibrant retail space in Columbia's dynamic BullStreet District.

    2151 Pickens St, Columbia, SC 29201

    View details
    Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 10 Active listings in Lexington County, SC, we suggest exploring alternatives. Similar 17 Properties for Sales.

    Similar Spaces for Sale in Lexington County, SC

    Consider Similar Space for Sale. We found 17 Spaces matching your search parameters.

    Versatile Commercial Property on Edmund Highway
    $799,000
    4,090 SF
    Versatile Commercial Property on Edmund Highway

    Commercial property with restaurant and warehouse in Lexington, SC.

    6196 Edmund Highway, Lexington, SC 29073

    View details
    Versatile Commercial Opportunity in Columbia
    $550,000
    3,960 SF
    Versatile Commercial Opportunity in Columbia

    Prime commercial site with existing structure and redevelopment potential.

    123 Lawand Drive, Columbia, SC 29210

    View details
    Mixed-Use Property in Lexington, SC
    $850,000
    10,000 SF
    Mixed-Use Property in Lexington, SC

    Mixed-use property with retail, residential, and warehouse units.

    2040 S Lake Drive, Lexington, SC 29072

    View details
    Prime Lexington Commercial Development Opportunity
    $450,000
    2,056 SF
    Prime Lexington Commercial Development Opportunity

    3.04 acres on high-traffic road, ideal for commercial development.

    1551 S Lake Drive, Lexington, SC 29073

    View details
    Office/Warehouse Space on Lake Murray
    $985,000
    5,384 SF
    Office/Warehouse Space on Lake Murray

    Functional office and warehouse space with convenient access to amenities.

    1682 Lake Murray Boulevard, Columbia, SC 29212

    View details
    Mixed-Use Building on Large Lot
    $1,850,000
    9,261 SF
    Mixed-Use Building on Large Lot

    Freestanding mixed-use building with highway frontage and redevelopment potential.

    3905 Fernandina Rd, Columbia, SC 29210

    View details
    Renovated Office and Living Space
    $925,000
    4,138 SF
    Renovated Office and Living Space

    Two-story building with flexible floorplan near Downtown Columbia.

    132 Stonemark Ln, Columbia, SC

    View details
    Two Notch Road Commercial Property
    $239,000
    15,600 SF
    Two Notch Road Commercial Property

    Highly visible commercial property with flexible use opportunities.

    4949 Two Notch Rd, Columbia, SC 29204

    View details
    Downtown Lexington Commercial Office Opportunity
    $400,000
    1,190 SF
    Downtown Lexington Commercial Office Opportunity

    Well-located office space near Lexington County Courthouse and Main Street.

    110 N Lake Dr, Lexington, SC 29072

    View details
    Commercial Opportunity in Lexington, SC
    $480,000
    1,600 SF
    Commercial Opportunity in Lexington, SC

    Well-located commercial property suitable for various uses in Lexington, SC.

    108 N Lake Dr, Lexington, SC 29072

    View details
    Leesville Commercial Land Investment
    $1,300,000
    10.56 Acres
    Leesville Commercial Land Investment

    10+ acres in Leesville, SC, ideal for commercial or mixed-use.

    1153 West Hampton Road, Leesville, SC 29070

    View details
    Retail/Flex Building in Downtown
    Contact for pricing
    7,500 SF
    Retail/Flex Building in Downtown

    Multi-tenant building with retail, showroom, office, and warehouse space.

    300 Huger Street, Columbia, SC 29201

    View details
    Office/Retail Building with Warehouse Space
    Contact for pricing
    4,891 SF
    Office/Retail Building with Warehouse Space

    Well-maintained office/retail building with warehouse space and convenient location.

    115 Clark Street, Chapin, SC 29036

    View details
    Downtown Columbia Redevelopment Opportunity
    Contact for pricing
    21,434 SF
    Downtown Columbia Redevelopment Opportunity

    One-acre redevelopment site at a prominent downtown intersection.

    1600 Bull Street, Columbia, SC 29201

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Atlanta Land for Lease
    $1,850/Mo
    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315

    View details
    Prime Commercial Acres For Lease
    $6,000/Mo
    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986

    View details
    MidTown Corner Lot For Rent
    Contact for pricing
    MidTown Corner Lot For Rent

    Corner lot with high visibility in growing Nashville neighborhood.

    1811 Charlotte Avenue, Nashville, TN 37203

    View details
    Prime Land in Jarrettsville Corridor
    Contact for pricing
    Prime Land in Jarrettsville Corridor

    1.55 acre parcel in Jarrettsville's business corridor.

    1753, Jarrettsville, MD 21084

    View details

    Lexington County, SC Mixed-use properties Market Trends and Statistics

    Explore Mixed-use properties leasing options in Lexington County, SC with 10 listings featured on our commercial real estate exchange. The current inventory includes 22,201 square feet of properties with an estimated lease value of $34 SF/Yr.

    Estimated lease rates for Mixed-use properties in Lexington County, SC begin at $1.31 SF/Yr, with an average of $17 SF/Yr and extend to $33 SF/Yr.
    List
    Map