Lee County, FL Commercial Real Estate for Sale

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2,288 properties
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Professional Office Space Available Soon
Professional Office Space Available Soon

4020 Del Prado Blvd S A-3, Cape Coral, FL 33904

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800 sqft 0.60 AC lot

Office space with open floor plan, private offices, and restroom.

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Professional Zoned Development Land
Professional Zoned Development Land

1207 SE 8th Pl, Cape Coral, FL 33990

$498,000
0.80 AC lot

Seven-lot parcel zoned Professional, with assessments fully paid and noted eligibility under Florida’s Live Local Act.

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Cleared Corner Commercial Land
Cleared Corner Commercial Land

2330-2370 Estero Boulevard, Fort Myers Beach, FL 33931

$2,220,000
0.19 AC lot

Cleared corner parcel with C-1 and CB zoning near Mango Street beach access.

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Window and Door Showroom
Window and Door Showroom

30 Mildred Drive, Fort Myers, FL 33901

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2,000 sqft

For sale retail showroom supporting a windows and doors business serving Southwest Florida.

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Licensed Nursery With Sales Stand
Licensed Nursery With Sales Stand

9320 Buckingham Road, Fort Myers, FL 33905

$375,000
1.12 AC lot

Fenced, gated grounds include a tiny office, storage, customer parking, and a well.

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9.37 Acre Redevelopment Site
9.37 Acre Redevelopment Site

11820 & 11860 Red Hibiscus Drive, Bonita Springs, FL 34135

$4,500,000
9 sqft

Redevelopment site near shopping and schools in Bonita Springs.

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Imperial Riverfront Land
Imperial Riverfront Land

12025 Carpenter Ln lot: 7, Bonita Springs, FL 34135

$895,000
3.00 AC lot

Eight-parcel assemblage with underground electric, water, sewer, and communication services already installed.

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Retail/Office Space in Cape Coral
Retail/Office Space in Cape Coral

814 SW Pine Island Rd 102, Cape Coral, FL 33991

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2,400 sqft

2,400 SF retail/office space in a high-traffic location.

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Cape Coral Office with Warehouse
Cape Coral Office with Warehouse

4427 SE 16th Pl 4, Cape Coral, FL 33904

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1,400 sqft

Office space with warehouse in multi-tenant building, South Cape.

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Remodeled Third-Floor Office Condo
Remodeled Third-Floor Office Condo

2401 First Street, Fort Myers, FL 33901

$995,000
0.29 AC lot

Full-floor office space offers controlled access and pre-approved rooftop terrace rights.

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Retail Space in Merchants Plaza
Retail Space in Merchants Plaza

159 Hancock Bridge Pkwy 8-10, Cape Coral, FL 33990

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3,200 sqft

3,200 SF retail space available February 2026.

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Cleared Commercial Land Parcel
Cleared Commercial Land Parcel

1937 SW Santa Barbara Pl, Cape Coral, FL 33991

$69,000
16,248 sqft 0.37 AC lot

Cleared, level triple-lot zoned for commercial and professional uses with utility services available nearby.

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Commercial Land with CP Zoning
Commercial Land with CP Zoning

523 SW 3rd Terrace, Cape Coral, FL 33991

$179,800
0.36 AC lot

CP-zoned commercial site with public utilities and permitted professional-office use potential subject to municipal approval.

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Standalone Warehouse with Drive-In Access
Standalone Warehouse with Drive-In Access

5580 Zip Dr, Fort Myers, FL 33905

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9,000 sqft 0.98 AC lot

9,000 SF standalone warehouse with clear-span space, multiple grade-level doors, and a covered loading area.

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12-Station Barbershop Retail Space
12-Station Barbershop Retail Space

10801 Corkscrew Rd Unit 188, Estero, FL 33928

$84,000
1,183 sqft

Newly built premises support a chair- or booth-rental operating model.

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Prime Fort Myers Beach Suite
Prime Fort Myers Beach Suite

6035 Estero Blvd, Fort Myers Beach, FL 33931

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1,420 sqft

Versatile 1,420 RSF suite on Estero Boulevard.

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Flexible Medical Office Suite
Flexible Medical Office Suite

1949 Maravilla Ave, Fort Myers, FL 33901

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1,200 sqft

Adaptable professional space suitable for medical, wellness, laboratory, or office use.

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Commercial Professional-Zoned Land
Commercial Professional-Zoned Land

1305 Tropicana Parkway W, Cape Coral, FL 33993

$120,000
0.23 AC lot

Commercial Professional-zoned lot with public sewer access and surrounding retail, residential, and service amenities.

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Two-Building Retail Entertainment Property
Two-Building Retail Entertainment Property

3758 Cleveland Ave, Fort Myers, FL 33901

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10,400 sqft 1.00 AC lot

Two-building retail property includes a turn-key remodeled nightclub and a tenanted retail building.

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Waterfront Hotel Property
Waterfront Hotel Property

12200/12210 Shoreview Drive, Cape Coral, FL 33993

$3,250,000
7,400 sqft 1.00 AC lot

Renovated hospitality property with direct waterfront, boat slips, and a multi-building guest accommodation layout.

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Equestrian Acreage with Stables
Equestrian Acreage with Stables

7535 Caloosa Drive, Bokeelia, FL 33922

$1,500,000
9.50 AC lot

AG-2-zoned property with paddocks, stables, outbuildings, and an occupied historic residence.

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Medical/Dental Development Site
Medical/Dental Development Site

22770 S Tamiami Trl, Estero, FL 33928

Contact for pricing
1 sqft 1.45 AC lot

Planned development site with an approved Development Order for a medical, dental, and executive office project.

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Downtown Fort Myers Modern Office
Downtown Fort Myers Modern Office

2401 1st St Ste 250, Fort Myers, FL 33901

$1,100,000
0.29 AC lot

Modern office space in downtown Fort Myers with premium finishes.

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Retail Space in Publix Center
Retail Space in Publix Center

18990 S Tamiami Trail, Fort Myers, FL 33908

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3,933 sqft

Retail space totaling 3,933 SF is available for lease in a Publix-anchored shopping center.

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