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    Florence County, SC Office Properties & Spaces for Lease

    16 results
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    Versatile Commercial Space in Florence
    $5,000 / Mo
    11,390 SF

    Versatile Commercial Space in Florence

    374 Darlington St, Florence, SC 29501

    Commercial property with bay doors, ideal for automotive or warehouse.

    • Prime Downtown Florence, SC location
    • Multiple bay doors for easy access and operations
    • Versatile space suitable for automotive, warehouse, or service‑related businesses
    • Abundant open space for vehicles, equipment, or flexible use
    • Dedicated office space for administrative functions
    Updated: Oct 11, 2025
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    Office Space Near Timrod Park
    $700 / Mo
    150 SF

    Office Space Near Timrod Park

    720 S Coit St, Florence, SC 29501

    Flexible office spaces in historic building near Timrod Park.

    • Flexible office sizes available to suit various needs.
    • Competitive rental rates.
    • Located directly across from Timrod Park, offering a serene environment.
    • Wi‑Fi and utilities included in the rental rate.
    • Ample parking for tenants and guests.
    Updated: Jun 5, 2025
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    Lake City Retail/Office Building
    $10 SF/Yr
    11,000 SF

    Lake City Retail/Office Building

    Retail/office building in Lake City available through 1/31/2032.

    231 Kelley St, Lake City, SC 29560
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    Downtown Florence Flex Space
    $7 SF/Yr
    9,880 SF

    Downtown Florence Flex Space

    9,880 SF Flex Warehouse For Lease

    312 Railroad Ave, Florence, SC 29506
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    Downtown Florence Office Suite A
    $226 SF/Yr
    1,400 SF

    Downtown Florence Office Suite A

    1400 sq ft Executive Office Space for Lease

    620 Evans St, Florence, SC 29501
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    Florence Office Space For Lease
    $10 SF/Yr
    2,300 SF

    Florence Office Space For Lease

    2300 sq ft Flex Space, I-95 Access

    1092 Church St, Florence, SC 29506
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    Florence Office Space: 7,145 SF
    $22 SF/Yr
    74,186 SF

    Florence Office Space: 7,145 SF

    Prime Florence Office: Modern, Customizable Space

    2701 Alex Lee Blvd, Florence, SC 29506
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    Downtown Florence Mixed-Use Gem
    $25 SF/Yr
    7,748 SF

    Downtown Florence Mixed-Use Gem

    Historic District, prime location, flexible space.

    127 Evans St, Florence, SC 29501
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    620 Evans St
    $216 SF/Yr
    3,000 SF

    620 Evans St

    Office Properties & Spaces

    620 Evans St, Florence, SC 29501
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    Prime Florence Office Space
    $26 SF/Yr
    3,600 SF

    Prime Florence Office Space

    Class A Office, 1,800 SF Available

    609 2Nd Loop Rd, Florence, SC 29505
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    Prime Florence Office Space
    $22 SF/Yr
    48,770 SF

    Prime Florence Office Space

    Executive Suites, Full-Service, 48,770 SF

    1831 Evans St, Florence, SC 29501
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    Florence Mall Retail Space
    Contact for pricing
    329,345 SF

    Florence Mall Retail Space

    Prime Florence, SC retail center

    1945 Palmetto St, Florence, SC 29501
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    Habersham Square Flex Space Available
    Contact for pricing
    2,450 SF

    Habersham Square Flex Space Available

    Modern Flex Space, Prime Location, 2450 sqft

    1838 Habersham Sq, Florence, SC 29501
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    Florence County Executive Office Space
    Contact for pricing
    16,800 SF

    Florence County Executive Office Space

    Modern Flex Space, 10,500 SF Available

    2315 Prosperity Way, Florence, SC 29501
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    Logan Plaza: Prime Office Space
    Contact for pricing
    7,900 SF

    Logan Plaza: Prime Office Space

    Florence, SC Office Suites Available

    1800 2Nd Loop Rd, Florence, SC 29501
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    Five Points Office Building, Florence SC
    $14 SF/Yr
    3,800 SF

    Five Points Office Building, Florence SC

    Prime Florence Office Space: 3,800 sq ft, Multiple Suites

    1803 Cherokee Rd, Florence, SC 29501
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    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 16 Active listings in Florence County, SC, we suggest exploring alternatives. Similar 11 Properties for Sales.

    Explore Similar Spaces for Sale in Florence County, SC

    Consider Similar Space for Sale. We found 11 Spaces in Nearby Locations matching your search parameters.

    Versatile Commercial Property Near Downtown
    $550,000
    67,518 SF

    Versatile Commercial Property Near Downtown

    Office, showroom, and warehouse space near downtown Florence, SC.

    121 Lawson St, Florence, SC 29501
    View details
    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    Office building with 7,517 square feet of space in Florence.

    1706 2Nd Loop Rd, Florence, SC 29501
    View details
    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC 29560
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    McLeod Physician Associates For Sale
    Contact for pricing
    2,666 SF

    McLeod Physician Associates For Sale

    2,666 SF medical office in Florence, SC for sale.

    1540 American Dr, Florence, SC 29505
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    Medical Office Building Near MUSC
    Contact for pricing
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Ct, Florence, SC 29505
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    Downtown Florence Business Technology Center
    Contact for pricing
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.

    187 E Evans St, Florence, SC 29506
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    Updated Commercial Building with Showroom
    $1,600,000

    Updated Commercial Building with Showroom

    Updated 15,600 SF commercial building with showroom and loading docks.

    209 N Church St, Lake City, SC 29560
    View details

    Florence County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Florence County, SC with 27 listings featured on our commercial real estate exchange. The current inventory includes 7,719,877,440 square feet of properties with an estimated lease value of $640 /Mo.

    Estimated lease rates for Office Properties & Spaces in Florence County, SC begin at $5 SF/Yr, with an average of $53 SF/Yr and extend to $226 SF/Yr.
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    Office Properties & Spaces by market

    Browse Office Properties & Spaces for Lease Near Florence, SC

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