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Florence County, SC Office Properties & Spaces for Lease

15 results
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Versatile Commercial Space in Florence
$5,000 /Mo
11,390 SF

Versatile Commercial Space in Florence

374 Darlington St, Florence, SC 29501

Commercial property with bay doors, ideal for automotive or warehouse.

  • Prime Downtown Florence, SC location
  • Multiple bay doors for easy access and operations
  • Versatile space suitable for automotive, warehouse, or service‑related businesses
  • Abundant open space for vehicles, equipment, or flexible use
  • Dedicated office space for administrative functions
Last Update: Oct 6
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Office Space Near Timrod Park
$700 /Mo
150 SF

Office Space Near Timrod Park

720 S Coit St, Florence, SC 29501

Flexible office spaces in historic building near Timrod Park.

  • Flexible office sizes available to suit various needs.
  • Competitive rental rates.
  • Located directly across from Timrod Park, offering a serene environment.
  • Wi‑Fi and utilities included in the rental rate.
  • Ample parking for tenants and guests.
Last Update: Jun 5
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Prime Florence Office Space
$22 SF/Yr
48,770 SF

Prime Florence Office Space

Executive Suites, Full-Service, 48,770 SF
1831 Evans St, Florence, SC 29501
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Florence County Executive Office Space
Contact for pricing
16,800 SF

Florence County Executive Office Space

Modern Flex Space, 10,500 SF Available
2315 Prosperity Way, Florence, SC 29501
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Florence Office Space For Lease
$10 SF/Yr
2,300 SF

Florence Office Space For Lease

2300 sq ft Flex Space, I-95 Access
1092 Church St, Florence, SC 29506
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Downtown Florence Office Suite A
$226 SF/Yr
1,400 SF

Downtown Florence Office Suite A

1400 sq ft Executive Office Space for Lease
620 Evans St, Florence, SC 29501
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Habersham Square Flex Space Available
Contact for pricing
2,450 SF

Habersham Square Flex Space Available

Modern Flex Space, Prime Location, 2450 sqft
1838 Habersham Sq, Florence, SC 29501
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Downtown Florence Flex Space
$7 SF/Yr
9,880 SF

Downtown Florence Flex Space

9,880 SF Flex Warehouse For Lease
312 Railroad Ave, Florence, SC 29506
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Logan Plaza: Prime Office Space
Contact for pricing
7,900 SF

Logan Plaza: Prime Office Space

Florence, SC Office Suites Available
1800 2Nd Loop Rd, Florence, SC 29501
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Florence Office Space: 7,145 SF
$22 SF/Yr
74,186 SF

Florence Office Space: 7,145 SF

Prime Florence Office: Modern, Customizable Space
2701 Alex Lee Blvd, Florence, SC 29506
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Downtown Florence Mixed-Use Gem
$25 SF/Yr
7,748 SF

Downtown Florence Mixed-Use Gem

Historic District, prime location, flexible space.
127 Evans St, Florence, SC 29501
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Florence Mall Retail Space
Contact for pricing
329,345 SF

Florence Mall Retail Space

Prime Florence, SC retail center
1945 Palmetto St, Florence, SC 29501
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Prime Florence Office Space
$26 SF/Yr
3,600 SF

Prime Florence Office Space

Class A Office, 1,800 SF Available
609 2Nd Loop Rd, Florence, SC 29505
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620 Evans St
$216 SF/Yr
3,000 SF

620 Evans St

Office Properties & Spaces
620 Evans St, Florence, SC 29501
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Lake City Retail/Office Building
$10 SF/Yr
11,000 SF

Lake City Retail/Office Building

Retail/office building in Lake City available through 1/31/2032.
231 Kelley St, Lake City, SC 29560
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Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 15 Active listings in Florence County, SC, we suggest exploring alternatives. Similar 10 Properties for Sales.

Explore Similar Spaces for Sale in Florence County, SC

Consider Similar Space for Sale. We found 10 Spaces in Nearby Locations matching your search parameters.

Historic Mixed-Use Building in Florence
$3,000,000
13 SF

Historic Mixed-Use Building in Florence

16,000 sq ft historic building in Downtown Florence for sale.
248 W Evans St Florence, Florence, SC 29501
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Downtown Florence Business Technology Center
$12,000,000
119,567 SF

Downtown Florence Business Technology Center

Office building in downtown Florence with investment and value-add potential.
187 E Evans St, Florence, SC 29506
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Pamplico Highway Commercial Opportunity
$229,900
0.80 Acres

Pamplico Highway Commercial Opportunity

Commercial lot on heavily traveled Pamplico Highway with multiple driveways.
1424 Pamplico Hwy, Florence, SC 29505
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Medical Office Building Near MUSC
$2,200,000
7,950 SF

Medical Office Building Near MUSC

Medical office building near MUSC campus with ample parking.
1929 Mountain Laurel Ct, Florence, SC 29505
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Florence Office Building For Sale
$1,500,000
7,517 SF

Florence Office Building For Sale

Office building with 7,517 square feet of space in Florence.
1706 2Nd Loop Rd, Florence, SC 29501
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McLeod Physician Associates For Sale
$1,384,320
2,666 SF

McLeod Physician Associates For Sale

2,666 SF medical office in Florence, SC for sale.
1540 American Dr, Florence, SC 29505
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Stand-Alone Office Building For Sale
$250,000
1,722 SF

Stand-Alone Office Building For Sale

Stand-alone office building with immediate occupancy in Lake City, SC.
215 John St, Lake City, SC 29560
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Florence Office Building - $285K
$285,000
1,829 SF

Florence Office Building - $285K

1,829 SF Office, High Traffic Area
2400 2Nd Loop Rd, Florence, SC 29501
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Historic Downtown Florence Medical Office
$1,350,000
12,411 SF

Historic Downtown Florence Medical Office

12,411 SF Medical Office Building, $1.35M
329 Irby St, Florence, SC 29501
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Florence County, SC Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Florence County, SC with 25 listings featured on our commercial real estate exchange. The current inventory includes 7,719,877,440 square feet of properties with an estimated lease value of $609 /Mo.

Estimated lease rates for Office Properties & Spaces in Florence County, SC begin at $2 SF/Yr, with an average of $50 SF/Yr and extend to $226 SF/Yr.
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