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    Florence, SC
    Mixed-Use

    Florence, SC Mixed-use Properties for Sale

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    Historic Mixed-Use Building in Florence
    Updated: Sep 10, 2025
    Historic Mixed-Use Building in Florence

    248,258, and 268 W. Evans St., Florence, SC 29501

    $2,700,000
    13 sqft
    Prime downtown Florence location in a thriving area.
    Expansive 16,000 sq ft historic building with limitless potential.
    Currently generating income with existing tenants (Law Firm, H&R Block, Smith Hair Studio).
    Includes 1.47 acres of land, offering room for growth and development.
    Features a substantial amount of parking with over 100 spaces, a rare amenity for downtown.
    View details
    Versatile Commercial Building on Acreage
    Updated: Mar 5
    Versatile Commercial Building on Acreage

    511 Irby Street, Florence, SC 29501

    $500,000
    1.09 AC lot
    1.09 acre lot
    Single tenant building
    Ample showroom and warehouse space
    Features two (2) rollup doors
    Totally fenced in
    View details
    Versatile Commercial Parcel Near Downtown
    Versatile Commercial Parcel Near Downtown

    121 N Lawson St, Florence, SC 29501

    Contact for pricing
    67,518 sqft 1.55 AC lot

    Office, showroom, and warehouse space less than one mile from Downtown.

    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Evans Street Commercial Redevelopment Opportunity
    Evans Street Commercial Redevelopment Opportunity

    617 W Evans St, Florence, SC 29501

    Contact for pricing
    1,200 sqft 0.75 AC lot

    Standalone building on Evans Street with redevelopment potential.

    View details
    Based on your search, we've compiled 38 Potential Opportunities for your consideration. Besides 4 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 26 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Leased 4-Unit Mixed-Use Building
    Leased 4-Unit Mixed-Use Building

    2614 E Highway 76, Marion, SC 29571

    $585,000
    7,200 sqft 0.85 AC lot

    Fully occupied commercial space combines office and retail uses with highway access and rear entry.

    View details
    Mixed-Use Redevelopment Property
    Mixed-Use Redevelopment Property

    114 E. Calhoun Street, Sumter, SC 29150

    $2,500,000
    36,538 sqft 4.25 AC lot

    Former grocery building with substantial acreage and General Commercial zoning.

    View details
    Two-Building Mixed-Use Property
    Two-Building Mixed-Use Property

    1090 Broad Street, Sumter, SC 29150

    $1,150,000
    10,942 sqft 1.05 AC lot

    Two parcels combine a vacant former finance office with an operating lounge/bar and public utilities.

    View details
    Downtown Marion Mixed-Use Building
    Downtown Marion Mixed-Use Building

    417 N Main St, Marion, SC 29571

    $299,000
    3,500 sqft 0.15 AC lot

    5,000 sq ft mixed-use building in historic downtown Marion.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Area Investment Opportunity
    Florence Area Investment Opportunity

    5723 E National Cemetery Rd, Florence, SC 29506

    $32,725

    Prime land in Florence, SC, with development potential.

    View details
    Cleared Lot in Marion, SC
    Cleared Lot in Marion, SC

    Phillips St., Marion, SC 29571

    Contact for pricing
    0.18 AC lot

    0.18-acre cleared lot ready for building in Marion, SC.

    View details
    Multiplex-Ready Residential Development Land
    Multiplex-Ready Residential Development Land

    Rice Street, Latta, SC 29565

    $45,000
    3.88 AC lot

    Nearly 4 acres in Latta with city water and sewer, offering flexible development options for residential or small multifamily uses.

    View details
    Multifamily-Ready Residential Land
    Multifamily-Ready Residential Land

    W Rice Street, Latta, SC 29565

    $45,000
    3.88 AC lot

    Nearly 4 acres in Latta with dual access points and city water and sewer available.

    View details

    Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1505 Palmetto St
    OFFICE/RESIDENTIAL (MIXED USE)

    1505 Palmetto St, Florence, SC 29501-4131

    $150,000
    Estimated value
    1,057 sqft 0.23 AC lot
    View details
    1459 Palmetto St
    OFFICE/RESIDENTIAL (MIXED USE)

    1459 Palmetto St, Florence, SC 29501-4173

    $375,000
    Estimated value
    1,519 sqft 0.46 AC lot
    View details
    2940 Shadeland Cir
    OFFICE/RESIDENTIAL (MIXED USE)

    2940 Shadeland Cir, Florence, SC 29501

    Value Estimation by Request
    2.00 AC lot
    View details
    2702 Irby St
    OFFICE/RESIDENTIAL (MIXED USE)

    2702 Irby St, Florence, SC 29505-3434

    $115,000
    Estimated value
    2,541 sqft 0.53 AC lot
    View details
    1506 Palmetto St
    OFFICE/RESIDENTIAL (MIXED USE)

    1506 Palmetto St, Florence, SC 29501-4132

    $260,000
    Estimated value
    2,978 sqft 0.40 AC lot
    View details
    1107 Evans St
    OFFICE/RESIDENTIAL (MIXED USE)

    1107 Evans St, Florence, SC 29506-2739

    $165,000
    Estimated value
    2,216 sqft 0.30 AC lot
    View details
    1115 Cheves St
    OFFICE/RESIDENTIAL (MIXED USE)

    1115 Cheves St, Florence, SC 29506-2709

    $215,000
    Estimated value
    0.39 AC lot
    View details
    100 Divine St
    OFFICE/RESIDENTIAL (MIXED USE)

    100 Divine St, Florence, SC 29506-2732

    $85,000
    Estimated value
    1,946 sqft 0.15 AC lot
    View details
    918 Santee Dr
    OFFICE/RESIDENTIAL (MIXED USE)

    918 Santee Dr, Florence, SC 29501-5738

    $140,000
    Estimated value
    1,316 sqft 10.41 AC lot
    View details
    1508 Palmetto St
    OFFICE/RESIDENTIAL (MIXED USE)

    1508 Palmetto St, Florence, SC 29501-4132

    $220,000
    Estimated value
    1,430 sqft 0.40 AC lot
    View details
    208 Saunders St
    OFFICE/RESIDENTIAL (MIXED USE)

    208 Saunders St, Florence, SC 29501-2814

    $70,000
    Estimated value
    768 sqft 0.15 AC lot
    View details
    1257 Sumter St, Unit 9
    OFFICE/RESIDENTIAL (MIXED USE)

    1257 Sumter St, Florence, SC 29501-2209

    Unit 9
    $35,000
    Estimated value
    672 sqft 0.17 AC lot
    View details
    Sc-327
    Individual retail properties

    0 Sc-327, Florence, SC 29506

    Value Estimation by Request
    1.38 AC lot
    View details
    130 Dargan St
    Individual retail properties

    130 Dargan St, Florence, SC 29506

    Value Estimation by Request
    6,520 sqft
    View details
    Us-76
    Lifestyle centers

    0 Us-76, Florence, SC 29506

    Value Estimation by Request
    10.55 AC lot
    View details
    Sc-327
    Lifestyle centers

    0 Sc-327, Florence, SC 29506

    Value Estimation by Request
    1.38 AC lot
    View details
    414 Irby St
    Retirement homes

    414 Irby St, Florence, SC 29501

    Value Estimation by Request
    6,427 sqft
    View details
    Williston Rd
    Multifamily properties

    0 Williston Rd, Florence, SC 29506

    Value Estimation by Request
    105.44 AC lot
    View details
    1368 Old Marion Hwy
    Mixed-use properties

    1368 Old Marion Hwy, Florence, SC 29506

    Value Estimation by Request
    1,919 sqft 6.62 AC lot
    View details
    Palmetto St
    Multifamily properties

    0 Palmetto St, Florence, SC 29506

    Value Estimation by Request
    36.58 AC lot
    View details

    Florence, SC Mixed-Use Properties Market Trends and Statistics

    Explore 30 mixed-use properties for sale in Florence, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 68,731 square feet of properties for sale, with an estimated market value of $3,200,000.

    Sale prices for multi use buildings in Florence, SC start at $500,000, averaging $1,600,000, and reaching up to $2,700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 92K
    Population Growth (5Y) -1.5%
    Median Household Income $61,793
    College Educated 17.4%

    High-Yield Neighborhoods for Investment

    Identify Florence submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29505 $275K
    29506 $429K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Florence County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Florence County

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    Featured Florence Real Estate Agencies

    Realmo connects you with licensed Florence CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Coldwell Banker McMillan and Associates
    419 S.Coit Street Florence, SC 29501
    Phone: 18436017710
    CBFlorence.com

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