Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Mixed-Use
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Florence, SC Mixed-use Properties for Sale

    List
    Map
    Columbia, SC Aiken, SC Greenville, SC
    7 results
    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    1714 Second Loop Rd., Florence, SC 29501

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    • 260' of road frontage on 2nd Loop Road offers high visibility.
    • Zoned Mixed‑Use allows for a wide range of commercial and community‑oriented uses.
    • Permitted uses include schools, churches, retail, offices, restaurants, and hotels.
    • Conditional approval for multi‑family, live/work units, and other diverse uses.
    • Ideal location for businesses seeking high traffic and accessibility.
    Updated: Feb 5, 2025
    View details
    Mixed-Use Property in Great Location
    $429,000
    3,764 SF

    Mixed-Use Property in Great Location

    605 S Dargan St, Florence, SC 29506

    Mixed-use property, previously commercial, next to medical staffing business.

    • Great Location!
    • Previously used for commercial purposes.
    • Located next door to a medical staffing business.
    • Currently occupied as a home by owner.
    • Year Built: 1930.
    Updated: Mar 11
    View details
    Versatile Commercial Parcel Near Downtown
    $499,900
    67,518 SF

    Versatile Commercial Parcel Near Downtown

    Office, showroom, and warehouse space less than one mile from Downtown.

    121 N Lawson St, Florence, SC 29501
    View details
    Evans Street Commercial Redevelopment Opportunity
    $79,000
    1,200 SF

    Evans Street Commercial Redevelopment Opportunity

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
    View details
    Mixed-Use Investment Property
    $275,000
    4,740 SF

    Mixed-Use Investment Property

    4740 SF mixed-use property with three rental units.

    1701 Pamplico Hwy, Florence, SC 29505
    View details
    Land with Highway Access
    $3,750,000

    Land with Highway Access

    Land with high traffic, accessibility, and visibility.

    N Williston Rd, Florence, SC 29506
    View details
    US Hwy 76 Frontage Land
    $2,000,000

    US Hwy 76 Frontage Land

    Commercial land with high visibility and accessibility on US Hwy 76.

    US-76, Florence, SC 29506
    View details
    Based on your search, we've compiled 41 Potential Opportunities for your consideration. Besides 7 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 26 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    High-Visibility Commercial Land Opportunity
    $399,900
    896 SF

    High-Visibility Commercial Land Opportunity

    7.2 acres with high traffic, ideal for diverse businesses.

    10145 Mccoll Road, Laurinburg, NC 28352
    View details
    Downtown Marion Mixed-Use Building
    $299,000
    3,500 SF

    Downtown Marion Mixed-Use Building

    5,000 sq ft mixed-use building in historic downtown Marion.

    417 N Main St, Marion, SC 29571
    View details
    Downtown Marion Retail Opportunity
    $250,000
    2,662 SF

    Downtown Marion Retail Opportunity

    Commercial retail space in downtown Marion with investment potential.

    516 & 514 N Main Street, Marion, SC 29571
    View details
    Laurinburg Commercial Building For Sale
    $239,000
    3,744 SF

    Laurinburg Commercial Building For Sale

    Commercial building with tenants in all three units for sale.

    124 W Cronly Street, Laurinburg, NC 28352
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Area Investment Opportunity
    Contact for pricing

    Florence Area Investment Opportunity

    Prime land in Florence, SC, near National Cemetery.

    5723 E National Cemetery Rd, Florence, SC 29506
    View details
    Latta Acreage with Development Potential
    $45,000
    3.88 Acres

    Latta Acreage with Development Potential

    3.88 acres in Latta, SC, suitable for various development projects.

    TBD W Rice Street, Latta, SC 29565
    View details
    Hartsville Commercial Land Opportunity
    $199,999
    11.47 Acres

    Hartsville Commercial Land Opportunity

    Prime commercial land near city with utilities and versatile zoning.

    1403 S Fifth Street, Hartsville, SC 29550
    View details
    Prime Commercial Land Opportunity
    $400,000
    1.02 Acres

    Prime Commercial Land Opportunity

    Commercial land on a busy highway, ideal for various businesses.

    Parcel C Highway 701, Loris, SC 29569
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1505 Palmetto St

    1505 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,057 SF
    Value Estimation by Request
    1505 Palmetto St, Florence, SC 29501-4131
    View details
    1459 Palmetto St

    1459 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,519 SF
    Value Estimation by Request
    1459 Palmetto St, Florence, SC 29501-4173
    View details
    2940 Shadeland Cir

    2940 Shadeland Cir

    OFFICE/RESIDENTIAL (MIXED USE) • 2.00 Acres
    Value Estimation by Request
    2940 Shadeland Cir, Florence, SC 29501
    View details
    2702 Irby St

    2702 Irby St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,541 SF
    Value Estimation by Request
    2702 Irby St, Florence, SC 29505-3434
    View details
    1506 Palmetto St

    1506 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,978 SF
    Value Estimation by Request
    1506 Palmetto St, Florence, SC 29501-4132
    View details
    1107 Evans St

    1107 Evans St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,216 SF
    Value Estimation by Request
    1107 Evans St, Florence, SC 29506-2739
    View details
    1115 Cheves St

    1115 Cheves St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.39 Acres
    Value Estimation by Request
    1115 Cheves St, Florence, SC 29506-2709
    View details
    100 Divine St

    100 Divine St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,946 SF
    Value Estimation by Request
    100 Divine St, Florence, SC 29506-2732
    View details
    918 Santee Dr

    918 Santee Dr

    OFFICE/RESIDENTIAL (MIXED USE) • 1,316 SF
    Value Estimation by Request
    918 Santee Dr, Florence, SC 29501-5738
    View details
    1508 Palmetto St

    1508 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,430 SF
    Value Estimation by Request
    1508 Palmetto St, Florence, SC 29501-4132
    View details
    208 Saunders St

    208 Saunders St

    OFFICE/RESIDENTIAL (MIXED USE) • 768 SF
    Value Estimation by Request
    208 Saunders St, Florence, SC 29501-2814
    View details
    1257 Sumter St, Unit 9

    1257 Sumter St, Unit 9

    OFFICE/RESIDENTIAL (MIXED USE) • 672 SF
    Value Estimation by Request
    1257 Sumter St, Florence, SC 29501-2209
    View details
    Sc-327

    Sc-327

    Individual retail properties • 1.38 Acres
    Value Estimation by Request
    0 Sc-327, Florence, SC 29506
    View details
    130 Dargan St

    130 Dargan St

    Individual retail properties • 6,520 SF
    Value Estimation by Request
    130 Dargan St, Florence, SC 29506
    View details
    Us-76

    Us-76

    Lifestyle centers • 10.55 Acres
    Value Estimation by Request
    0 Us-76, Florence, SC 29506
    View details
    Sc-327

    Sc-327

    Lifestyle centers • 1.38 Acres
    Value Estimation by Request
    0 Sc-327, Florence, SC 29506
    View details
    414 Irby St

    414 Irby St

    Retirement homes • 6,427 SF
    Value Estimation by Request
    414 Irby St, Florence, SC 29501
    View details

    Florence, SC Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 33 mixed-use properties for sale in Florence, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 755,093 square feet of properties for sale, with an estimated market value of $3,470,000.

    Sale prices for multi use buildings in Florence, SC start at $115,000, averaging $385,555, and reaching up to $1,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Mixed-use properties for Sale Near Florence, SC

    Popular Searches in Florence, SC

    Popular Categories

    Most Searched ZIP Codes in Florence, SC

    • 29501
    • 29506
    • 29505

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!