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    South Carolina Mixed-use Properties for Sale

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    Found 221 mixed-use property listings for sale in South Carolina, averaging $248/sq ft. Use valuation data to compare deals faster.
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    Historic Office Building
    Historic Office Building

    248-260 W Evans st., Florence, SC 29501

    $2,700,000
    16,304 sqft 1.47 AC lot

    Established professional layout with multiple occupants, meeting rooms, reception space, and dedicated parking in downtown Florence.

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    Three-Suite Mixed-Use Property
    Three-Suite Mixed-Use Property

    480 Nelson Blvd., Kingstree, SC 29556

    $600,000
    21,275 sqft 2.10 AC lot

    Commercially zoned property with separate suites suited to office, retail, or multiple business operations.

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    Historic Mixed-Use Building
    Historic Mixed-Use Building

    222 City Square, Belton, SC 29627

    $299,000
    8,000 sqft 0.11 AC lot

    Downtown property with commercial space, residential adaptation potential, and access to public water service.

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    Downtown Mixed-Use Property
    Downtown Mixed-Use Property

    117 Asbury Ave, Greenville, SC 29601

    $519,000
    1,732 sqft

    Existing infill building with MX-2 zoning, flexible room layout, hardwood floors, and strong natural light.

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    Two-Story Mixed-Use Brick Property
    Two-Story Mixed-Use Brick Property

    314,316,318 N Limestone Street, Gaffney, SC 29340

    $190,000
    8,400 sqft 0.26 AC lot

    Three ground-floor retail units include showroom, storage, and bathroom space.

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    Mixed-Use Property with Offices
    Mixed-Use Property with Offices

    4123 Meeting St., Loris, SC 29569

    $374,999
    5,275 sqft 0.13 AC lot

    Flexible commercial layout includes private offices, updated units, and infrastructure supporting food service build-out.

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    Corner Storefront with Warehouse Space
    Corner Storefront with Warehouse Space

    315 E Main Street, Dillon, SC 29536

    $495,000
    24,388 sqft 0.45 AC lot

    Brick-and-block commercial building with showroom, offices, loading access, and covered pedestrian frontage.

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    Mixed-Use Property with Ice Cream Shop
    Mixed-Use Property with Ice Cream Shop

    612 S Ocean Blvd., Myrtle Beach, SC 29577

    $1,250,000
    2,910 sqft

    Four-bedroom residential space is positioned above an equipped retail operation with the existing ice cream business included.

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    Mixed-Use Commercial Property
    Mixed-Use Commercial Property

    2090 Peach Orchard Road, Sumter, SC 29154

    $675,000
    10,423 sqft 7.50 AC lot

    Four leased retail shops and a rented mechanic garage provide an established operating mix.

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    Mixed-Use Property with Warehouse
    Mixed-Use Property with Warehouse

    2040 S Lake Drive, Lexington, SC 29072

    $750,000
    10,000 sqft 1.07 AC lot

    Retail, residential, and warehouse components occupy a mixed-use commercial property.

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    Mixed-Use Office Property
    Mixed-Use Office Property

    565 Savannah Highway, Charleston, SC 29407

    $1,250,000
    3,018 sqft

    Flexible ground-floor layout with kitchen and mixed-use zoning for business and residential uses.

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    Waterfront Mixed-Use Property
    Waterfront Mixed-Use Property

    Saint Helena Island, SC 29920

    $1,750,000
    0.93 AC lot

    Restaurant, open market, and two separate one-bedroom living spaces share a commercial waterfront setting.

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    Mixed-Use Property with Residential Units
    Mixed-Use Property with Residential Units

    134 Professional Ln., Pawleys Island, SC 29585

    $1,590,000
    4,584 sqft 1.00 AC lot

    Four-unit commercial and residential configuration supports owner-user, rental, and live/work arrangements under GC zoning.

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    Mixed-Use Property with Warehouse
    Mixed-Use Property with Warehouse

    1095 Southport Rd, Spartanburg, SC 29306

    $2,500,000
    24,000 sqft 3.48 AC lot

    Office and conditioned production space are paired with a fenced outdoor yard for storage and equipment staging.

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    Wedding Venue With Open Event Space
    Wedding Venue With Open Event Space

    3825 Saluda Dam Road, Easley, SC 29640

    $2,000,000
    2.13 AC lot

    Heated and cooled commercial facility with flexible event, office, classroom, kitchen, restroom, and support areas.

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    Mixed-Use Property with Wood Flooring
    Mixed-Use Property with Wood Flooring

    511 Foster Street, Union, SC 29379

    $128,000
    1,896 sqft 0.55 AC lot

    Commercial building with wood flooring and public water service.

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    Multi-Level Mixed-Use Building
    Multi-Level Mixed-Use Building

    222 E Main St, Walhalla, SC 29691

    $750,000
    16,515 sqft

    Multiple floors offer flexibility for restaurant, retail, lodging, office, or residential configurations.

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    Three-Story Mixed-Use Property
    Three-Story Mixed-Use Property

    651 King Street, Charleston, SC 29403

    $4,695,000
    4,253 sqft 0.05 AC lot

    Modern Charleston asset combining short-term lodging with leased commercial space and restaurant-ready infrastructure.

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    Mixed-Use Property with Metal Buildings
    Mixed-Use Property with Metal Buildings

    4750 Hwy 17 S Unit 4583 Wesley RD, Murrells Inlet, SC 29576

    $4,399,000
    23,000 sqft 6.50 AC lot

    PUD GC zoning and an approved conceptual plan support a combination of commercial uses.

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    Three-Story Mixed-Use Building
    Three-Story Mixed-Use Building

    112 W Main Street, Walhalla, SC 29691

    $829,000
    0.96 AC lot

    Flexible commercial property with offices, salon suites, retail-style rooms, event space, and covered outdoor areas.

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    Historic Mixed-Use Property
    Historic Mixed-Use Property

    695 Main Street, Wellford, SC 29385

    $599,000
    4,513 sqft 2.13 AC lot

    C-1 zoning and a separate workshop complement the six-bedroom main house.

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    Mixed-Use Property with Lounge
    Mixed-Use Property with Lounge

    1090 Broad Street, Sumter, SC 29150

    $1,150,000
    10,942 sqft 1.05 AC lot

    Two-building commercial property combining vacant office space with an operating lounge/bar and a billboard generating annual income.

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    Mixed-Use Estate with Event Space
    Mixed-Use Estate with Event Space

    105 Marshland Lane, Greer, SC 29650

    $1,099,000
    7,000 sqft 1.60 AC lot

    Flexible accommodations and an on-site gathering area support hospitality, rental, and private-use possibilities subject to applicable approvals.

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    Mixed-Use Property with Office/Garage
    Mixed-Use Property with Office/Garage

    1560 G P Smith Ave., Longs, SC 29568

    $599,000
    1,800 sqft 1.03 AC lot

    Includes a three-bay office and garage with a waiting area and bathroom, plus a refurbished residential unit.

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