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    Greenville County, SC Office Buildings for Sale

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    63 properties
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    Single-Level Brick Medical Office
    Updated: Apr 20
    Single-Level Brick Medical Office

    203 S Weston Street, Fountain Inn, SC 29644

    $1,500,000
    0.59 AC lot
    Medical office property at 201 and 203 S Weston Street
    C‑1 zoning with 0.59 acres included
    Single‑level brick building built in the 1950s
    Adjacent lot provides over 30 parking spaces
    24x24 brick outbuilding included
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    Single-Level Office Building
    Updated: Jul 24
    Single-Level Office Building

    1 Elizabeth Drive, Greenville, SC 29615

    $384,900
    0.34 AC lot
    Approximately 1,600 SF single‑level office building
    3 offices plus reception area, kitchen/breakroom, storage, and 2 restrooms
    Approximately 9 parking spaces; 5 in front and 4 at the rear
    1 handicap parking space and rear accessibility ramp
    NC zoning in the Wade Hampton Boulevard area
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    Multi-Building Office Property
    Multi-Building Office Property

    413 Vardry Street, Greenville, SC 29601

    $3,499,000
    0.75 AC lot

    Brick office complex with multiple buildings, dedicated parking, exterior signage, and OD zoning near central Greenville.

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    Single-Story Office Building
    Single-Story Office Building

    121 Edinburgh Ct, Greenville, SC 29607

    $1,300,000
    5,675 sqft

    MX-2-zoned office property with two separate entrances and shared parking.

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    Freestanding Office Building on Corner Lot
    Freestanding Office Building on Corner Lot

    106 S Texas Avenue, Greenville, SC 29611

    $495,000
    0.57 AC lot

    Freestanding office building with Office District (OD) zoning and public water service on a prominent corner parcel.

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    Two-Level Office Building
    Two-Level Office Building

    221 Adley Way, Greenville, SC 29607

    $475,000
    0.06 AC lot

    Office property with an occupied lower level, available upper floor, parking, and adaptable professional-use space.

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    Freestanding Office Building
    Freestanding Office Building

    106 S Texas Avenue, Greenville, SC 29611

    $495,000
    0.57 AC lot

    Freestanding office building with an executive office, multiple private offices, reception area, and on-site parking.

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    Office Building with Available Space
    Office Building with Available Space

    110 Frederick Street, Greenville, SC 29607

    $7,950,000
    46,028 sqft 4.38 AC lot

    Partially leased office building with substantial available space for expansion or re-tenanting at 110 Frederick St.

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    Office Building
    Office Building

    1601 Rutherford Road, Greenville, SC 29609

    $390,000
    0.28 AC lot

    S-1-zoned office property with linoleum and tile flooring.

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    C-2 Office Building
    C-2 Office Building

    1908 N Pleasantburg Drive, Greenville, SC 29609

    $398,500
    0.47 AC lot

    The property features block construction, carpeted interiors, and natural-gas heating.

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    Freestanding Office Building
    Freestanding Office Building

    106 S Texas Avenue, Greenville, SC 29611

    $495,000
    2,384 sqft 0.57 AC lot

    Mid-century design, private offices, natural light, and a flexible layout support professional occupancy.

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    Freestanding Office Building
    Freestanding Office Building

    414b Pettigru Street, Greenville, SC 29601

    $562,500
    2,500 sqft

    Functional office accommodation with parking for tenants and visitors.

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    Office Building with Flexible Occupancy
    Office Building with Flexible Occupancy

    1247-1251 S Pleasantburg Dr, Greenville, SC 29605

    Contact for pricing
    9,877 sqft 0.51 AC lot

    Office property offering a partially leased configuration, available space, and existing cubicles and FF&E that may remain.

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    Redevelopment Mixed-Use Site
    Redevelopment Mixed-Use Site

    610 N Main St, Greenville, SC 29611

    Contact for pricing
    8,700 sqft 0.70 AC lot

    Two-parcel assemblage with an office building in shell condition and an occupied retail/entertainment building.

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    Two Office Buildings For Sale
    Two Office Buildings For Sale

    102 Renaissance Cir, Mauldin, SC 29662

    $299,000
    1,800 sqft

    Two-story office buildings in master-planned park, ideal for investors.

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    Leased Restaurant with Upstairs Office
    Leased Restaurant with Upstairs Office

    110 Poinsett Hwy, Greenville, SC 29609

    Contact for pricing
    8,400 sqft

    Recently renovated restaurant includes a full kitchen, bar, and upstairs office/event space with dedicated and shared parking.

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    Historic 3-Story Office Building
    Historic 3-Story Office Building

    412 Pettigru St, Greenville, SC 29601

    Contact for pricing
    2,121 sqft

    Spacious three-story office in Greenville with lots of natural light and parking.

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    Medical Office with Basement
    Medical Office with Basement

    202 Memorial Drive, Greer, SC 29650

    Contact for pricing
    1,144 sqft 0.34 AC lot

    The property includes on-site parking and additional basement area for potential office conversion.

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    Office Building
    Office Building

    9 Halton Green Way, Greenville, SC 29607

    Contact for pricing
    6,136 sqft

    Built in 2008, this Greenville property carries BG zoning.

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    Office Building Near Signalized Intersection
    Office Building Near Signalized Intersection

    2091 Locust Hill Rd, Greer, SC 29651

    Contact for pricing
    1,660 sqft

    Office building positioned near a lighted intersection with access from Locust Hill Road and N. Rutherford Road.

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    Freestanding Building on High-Traffic Corridor
    Freestanding Building on High-Traffic Corridor

    303 E Stone Ave, Greenville, SC 29609

    Contact for pricing
    2,000 sqft 0.30 AC lot

    Well-maintained 2,000 SF building on 0.3-acre site for sale.

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    Office Building at Signalized Intersection
    Office Building at Signalized Intersection

    730 S Pleasantburg Dr, Greenville, SC 29607

    Contact for pricing
    58,092 sqft

    Office building with white-box suites, updated mechanicals, and roof warranty through 2040.

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    Office Building
    Office Building

    50 Datastream Plz, Greenville, SC 29605

    Contact for pricing
    124,839 sqft

    Office property positioned within a commercial setting in Greenville.

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    Craftsman-Style Office Building
    Craftsman-Style Office Building

    108A Clair Drive, Piedmont, SC 29673

    Contact for pricing
    2,250 sqft

    Office building includes 6 private offices, reception, conference room, and 9-foot ceilings with shared paved parking access.

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    Greenville County, SC Office Buildings Market Trends and Statistics

    Explore 72 office buildings for sale in Greenville County, SC, showcased through 63 active listings on our real estate platform. These investment opportunities span a total of 891,116 square feet of properties for sale, with an estimated market value of $24,956,400.

    Sale prices for office properties in Greenville County, SC start at $265,000, averaging $1,247,820, and reaching up to $7,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Greenville County Real Estate Agencies

    Realmo connects you with licensed Greenville County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Keller Williams Greenville Upstate
    403 Woods Lake Rd Greenville, SC 29607
    Phone: 18642347500
    www.kwgreenvillesc.com
    BlackStream International Real Estate
    20 Overbrook Court, Suite 400 Greenville, SC 29607
    Phone: 18645531998
    www.blackstreaminternational.com
    Coldwell Banker Caine
    111 Williams Street Greenville, SC 29601
    Phone: 18642502800
    cbcaine.com

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