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Greenville County, SC Office Buildings for Sale

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43 properties
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Single-Level Brick Medical Office
Updated: Apr 20
Single-Level Brick Medical Office

203 S Weston Street, Fountain Inn, SC 29644

$1,500,000
0.59 AC lot
Medical office property at 201 and 203 S Weston Street
C‑1 zoning with 0.59 acres included
Single‑level brick building built in the 1950s
Adjacent lot provides over 30 parking spaces
24x24 brick outbuilding included
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Single-Level Office Building
Updated: Jul 24
Single-Level Office Building

1 Elizabeth Drive, Greenville, SC 29615

$379,900
0.34 AC lot
Approximately 1,600 SF office building on 0.34 acres
Three offices plus reception, kitchen/breakroom, storage, and 2 restrooms
Approximately 9 parking spaces, including 1 handicap space
New interior and exterior paint with refreshed landscaping
NC zoning in the Wade Hampton Boulevard area
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Multi-Building Office Property
Multi-Building Office Property

413 Vardry Street, Greenville, SC 29601

$3,499,000
0.75 AC lot

Brick office complex with multiple buildings, dedicated parking, exterior signage, and OD zoning near central Greenville.

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Finished Office Warehouse Building
Finished Office Warehouse Building

165 South Hammett Road, Greer, SC 29651

$1,700,000
9,300 sqft 2.48 AC lot

Well-maintained finished office building with an efficient office/warehouse mix and two drive-in doors for light loading.

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Two-Level Office Building
Two-Level Office Building

221 Adley Way, Greenville, SC 29607

$450,000
0.06 AC lot

Office property with an occupied lower level, available upper floor, parking, and adaptable professional-use space.

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Office Building
Office Building

1601 Rutherford Road, Greenville, SC 29609

$390,000
0.28 AC lot

S-1-zoned office property with linoleum and tile flooring.

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Flexible Mixed-Use Property
Flexible Mixed-Use Property

906 Augusta Street, Greenville, SC 29605

$1,395,000
0.35 AC lot

MX2-zoned building with four exterior entrances, a new roof, and dedicated parking near downtown Greenville.

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Office Building with Dedicated Parking
Office Building with Dedicated Parking

308 W Stone Ave, Greenville, SC 29609

$660,000
1,380 sqft

A five-office layout includes a reception area and a separate break room with kitchenette.

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C-2 Office Building
C-2 Office Building

1908 N Pleasantburg Drive, Greenville, SC 29609

$369,500
0.47 AC lot

The property features block construction, carpeted interiors, and natural-gas heating.

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Freestanding Office Building
Freestanding Office Building

106 S Texas Avenue, Greenville, SC 29611

$495,000
0.57 AC lot

Mid-century office property with private offices, reception space, natural light, and short dock access.

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Single-Story Office Building
Single-Story Office Building

121 Edinburgh Ct, Greenville, SC 29607

$1,300,000
5,675 sqft

MX-2-zoned office property with two separate entrances and shared parking.

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Freestanding Office Building
Freestanding Office Building

106 S Texas Avenue, Greenville, SC 29611

$495,000
0.57 AC lot

Owner-user or investment office property with private offices, reception space, natural light, and short dock access.

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Office Building with Available Space
Office Building with Available Space

110 Frederick Street, Greenville, SC 29607

$7,950,000
46,028 sqft 4.38 AC lot

Partially leased office building with substantial available space for expansion or re-tenanting at 110 Frederick St.

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Renovated Flex Building
Renovated Flex Building

427 WADE HAMPTON BLVD, Greenville, SC 29609

Contact for pricing
6,000 sqft 0.55 AC lot

MX-2 zoning and a flexible interior configuration support office, retail, and other commercial uses.

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Freestanding Office Building
Freestanding Office Building

106 S Texas Avenue, Greenville, SC 29611

$495,000
2,384 sqft 0.57 AC lot

Mid-century design, private offices, natural light, and a flexible layout support professional occupancy.

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Redevelopment Mixed-Use Site
Redevelopment Mixed-Use Site

610 N Main St, Greenville, SC 29611

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8,700 sqft 0.70 AC lot

Two-parcel assemblage with an office building in shell condition and an occupied retail/entertainment building.

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Two Office Buildings For Sale
Two Office Buildings For Sale

102 Renaissance Cir, Mauldin, SC 29662

$299,000
1,800 sqft

Two-story office buildings in master-planned park, ideal for investors.

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Medical Office Space with Existing Buildout
Medical Office Space with Existing Buildout

717 NE Main St, Simpsonville, SC 29681

Contact for pricing
3,000 sqft

Existing chiropractic-office configuration supports continued professional use or conversion for legal and accounting services.

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Historic 3-Story Office Building
Historic 3-Story Office Building

412 Pettigru St, Greenville, SC 29601

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2,121 sqft

Spacious three-story office in Greenville with lots of natural light and parking.

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Medical Office with Basement
Medical Office with Basement

202 Memorial Drive, Greer, SC 29650

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1,144 sqft 0.34 AC lot

The property includes on-site parking and additional basement area for potential office conversion.

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Office Building
Office Building

9 Halton Green Way, Greenville, SC 29607

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6,136 sqft

Built in 2008, this Greenville property carries BG zoning.

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Office Building Near Signalized Intersection
Office Building Near Signalized Intersection

2091 Locust Hill Rd, Greer, SC 29651

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1,660 sqft

Office building positioned near a lighted intersection with access from Locust Hill Road and N. Rutherford Road.

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Freestanding Building on High-Traffic Corridor
Freestanding Building on High-Traffic Corridor

303 E Stone Ave, Greenville, SC 29609

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2,000 sqft 0.30 AC lot

Well-maintained 2,000 SF building on 0.3-acre site for sale.

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Office Building
Office Building

50 Datastream Plz, Greenville, SC 29605

Contact for pricing
124,839 sqft

Office property positioned within a commercial setting in Greenville.

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Greenville County, SC Office Buildings Market Trends and Statistics

Explore 72 office buildings for sale in Greenville County, SC, showcased through 43 active listings on our real estate platform. These investment opportunities span a total of 371,747 square feet of properties for sale, with an estimated market value of $30,994,400.

Sale prices for commercial office buildings in Greenville County, SC start at $199,000, averaging $1,408,836, and reaching up to $7,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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