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    Greenville County, SC Office Spaces for Sale

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    81 properties
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    Single-Level Brick Medical Office
    Updated: Apr 20
    Single-Level Brick Medical Office

    203 S Weston Street, Fountain Inn, SC 29644

    $1,500,000
    0.59 AC lot
    Medical office property at 201 and 203 S Weston Street
    C‑1 zoning with 0.59 acres included
    Single‑level brick building built in the 1950s
    Adjacent lot provides over 30 parking spaces
    24x24 brick outbuilding included
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    Corner Mixed-Use Property
    Updated: May 21
    Corner Mixed-Use Property

    Poinsett Highway, Greenville, SC 29609

    $1,400,000
    0.72 AC lot
    Two 5,000‑square‑foot commercial buildings
    0.72‑acre corner parcel on Poinsett Highway
    Reported daily traffic count exceeding 40,000
    Parking area included on site
    Public water service
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    Office Property with Great Room
    Office Property with Great Room

    103 Mimosa Drive, Greer, SC 29650

    $435,000
    0.64 AC lot

    A converted residence offers multiple rooms, on-site parking, and a screened porch with driveway access.

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    Office/Warehouse with Drive-In Door
    Office/Warehouse with Drive-In Door

    9 Ellwood Ct, Greenville, SC 29607

    $1,900,000
    13,171 sqft 1.20 AC lot

    Office warehouse building with assembly space plus both dock and drive-in access for flexible industrial operations.

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    Single-Level Office Building
    Single-Level Office Building

    1 Elizabeth Drive, Greenville, SC 29615

    $379,900
    0.34 AC lot

    NC-zoned property with three offices, reception space, and on-site parking.

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    Multi-Building Office Property
    Multi-Building Office Property

    413 Vardry Street, Greenville, SC 29601

    $3,499,000
    0.75 AC lot

    Brick office complex with multiple buildings, dedicated parking, exterior signage, and OD zoning near central Greenville.

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    Two-Level Office Building
    Two-Level Office Building

    221 Adley Way, Greenville, SC 29607

    $450,000
    0.06 AC lot

    Office property with an occupied lower level, available upper floor, parking, and adaptable professional-use space.

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    Finished Office Warehouse Building
    Finished Office Warehouse Building

    165 South Hammett Road, Greer, SC 29651

    $1,700,000
    9,300 sqft 2.48 AC lot

    Well-maintained finished office building with an efficient office/warehouse mix and two drive-in doors for light loading.

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    Office Building
    Office Building

    1601 Rutherford Road, Greenville, SC 29609

    $390,000
    0.28 AC lot

    S-1-zoned office property with linoleum and tile flooring.

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    Flexible Mixed-Use Property
    Flexible Mixed-Use Property

    906 Augusta Street, Greenville, SC 29605

    $1,395,000
    0.35 AC lot

    MX2-zoned building with four exterior entrances, a new roof, and dedicated parking near downtown Greenville.

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    Office Building with Dedicated Parking
    Office Building with Dedicated Parking

    308 W Stone Ave, Greenville, SC 29609

    $660,000
    1,380 sqft

    A five-office layout includes a reception area and a separate break room with kitchenette.

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    C-2 Office Building
    C-2 Office Building

    1908 N Pleasantburg Drive, Greenville, SC 29609

    $369,500
    0.47 AC lot

    The property features block construction, carpeted interiors, and natural-gas heating.

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    Freestanding Office Building
    Freestanding Office Building

    106 S Texas Avenue, Greenville, SC 29611

    $495,000
    0.57 AC lot

    Mid-century office property with private offices, reception space, natural light, and short dock access.

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    Historic Creative Workspace
    Historic Creative Workspace

    300 South St, Simpsonville, SC 29681

    $1,750,000
    8,082 sqft

    Flexible commercial layout with open work areas, private rooms, offices, restrooms, a breakroom, and an outdoor patio.

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    Freestanding Office Building
    Freestanding Office Building

    106 S Texas Avenue, Greenville, SC 29611

    $495,000
    0.57 AC lot

    Owner-user or investment office property with private offices, reception space, natural light, and short dock access.

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    Historic Mixed-Use Property with Sunroom
    Historic Mixed-Use Property with Sunroom

    1011 W Poinsett Street, Greer, SC 29650

    $685,000
    3,051 sqft

    Distinctive former doctor’s office with period detailing, a detached workshop garage, and flexibility for office, residential, or event use.

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    Single-Story Office Building
    Single-Story Office Building

    121 Edinburgh Ct, Greenville, SC 29607

    $1,300,000
    5,675 sqft

    MX-2-zoned office property with two separate entrances and shared parking.

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    Downtown Mixed-Use Property
    Downtown Mixed-Use Property

    117 Asbury Ave, Greenville, SC 29601

    $519,000
    1,732 sqft

    Existing infill building with MX-2 zoning, flexible room layout, hardwood floors, and strong natural light.

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    Office Building with Available Space
    Office Building with Available Space

    110 Frederick Street, Greenville, SC 29607

    $7,950,000
    46,028 sqft 4.38 AC lot

    Partially leased office building with substantial available space for expansion or re-tenanting at 110 Frederick St.

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    Office Unit with On-Site Parking
    Office Unit with On-Site Parking

    1106 Pendleton St, Greenville, SC 29601

    $475,000
    1,229 sqft

    MX-2 zoning and on-site parking support a range of office configurations.

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    Mixed-Use Corner Assemblage
    Mixed-Use Corner Assemblage

    302 W Washington Street, Greenville, SC 29601

    $8,500,000
    58,662 sqft 2.07 AC lot

    Five contiguous parcels combine existing improvements with flexibility for office, institutional, warehouse, or adaptive reuse applications.

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    Simpsonville Commercial Building For Sale
    Simpsonville Commercial Building For Sale

    313 N Main Street, Simpsonville, SC 29681

    $3,995,000
    24,000 sqft

    24,000 SF building in Simpsonville, SC, renovated in 2013.

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    Greenville Flex Facility Near Trail
    Greenville Flex Facility Near Trail

    17 Pinsley Cir, Greenville, SC 29617

    $1,600,000
    10,000 sqft

    10,000 SF flex facility on 2-acre fenced lot.

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    Renovated Flex Building
    Renovated Flex Building

    427 WADE HAMPTON BLVD, Greenville, SC 29609

    Contact for pricing
    6,000 sqft 0.55 AC lot

    MX-2 zoning and a flexible interior configuration support office, retail, and other commercial uses.

    View details
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    Greenville County, SC Office Spaces Market Trends and Statistics

    Explore 81 office spaces for sale in Greenville County, SC, showcased through 81 active listings on our real estate platform. These investment opportunities span a total of 595,769 square feet of properties for sale, with an estimated market value of $55,307,900.

    Sale prices for office properties in Greenville County, SC start at $140,000, averaging $1,536,330, and reaching up to $8,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Greenville County Real Estate Agencies

    Realmo connects you with licensed Greenville County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Keller Williams Greenville Upstate
    403 Woods Lake Rd Greenville, SC 29607
    Phone: 18642347500
    www.kwgreenvillesc.com
    BlackStream International Real Estate
    20 Overbrook Court, Suite 400 Greenville, SC 29607
    Phone: 18645531998
    www.blackstreaminternational.com
    Coldwell Banker Caine
    111 Williams Street Greenville, SC 29601
    Phone: 18642502800
    cbcaine.com
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