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Niles, MI Commercial Real Estate for Sale

36 results
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Joey Armadillos   (Formally Shulas)
$1,700,000
17,500 SF

Joey Armadillos (Formally Shulas)

Turnkey Bowling Center – 24 Lanes, Restaurant, Bar & Event Business

2732 s 11Th St, Niles, MI 49120
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Niles Commercial Property with Acreage
$650,000
8,600 SF

Niles Commercial Property with Acreage

1115 State Line Road, Niles, MI 49120

Versatile commercial property with multiple buildings and flexible space.

  • 2.2+ acre commercial property with multiple buildings and flexible space.
  • Main 5000 sq ft building features a finished office area (kitchen, 2 offices, restroom) and attached heated warehouse.
  • 60x60 building boasts ten overhead doors, ideal for fleet storage or multi‑bay work areas.
  • Adaptable for various business uses needing office, warehouse, and extensive storage.
  • Detached garage for secure equipment storage.
Updated: Dec 12, 2025
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Versatile Commercial Property on High-Traffic Street
$515,000
3,200 SF

Versatile Commercial Property on High-Traffic Street

2604 S 11th Street, Niles, MI 49120

40x80 commercial property with live/work space and ample parking.

  • Prime location on high‑traffic 11th Street.
  • Separate living quarters with private entrance, perfect for live/work or on‑site management.
  • Three‑phase electric and compressed air lines throughout the building.
  • Deep lot with ample parking and potential for an additional structure.
  • 12x12 overhead door for easy access.
Updated: Oct 17, 2025
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Versatile Commercial Building in Niles
$269,000
6,716 SF

Versatile Commercial Building in Niles

Handicap accessible, open floor plan suitable for diverse uses.

1724 E Bertrand Road, Niles, MI 49120
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Retail Property on High-Traffic Corridor
$1,300,000
3,140 SF

Retail Property on High-Traffic Corridor

Retail property in Niles' primary commercial area with high visibility.

1295 S 11th Street, Niles, MI 49120
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Retail Property in Niles, MI
$550,000
720 SF

Retail Property in Niles, MI

Retail space for sale in high-traffic Niles, Michigan location.

2142 S 11th Street, Niles, MI 49120
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Updated Multi-Tenant Commercial Space
$695,000
15,822 SF

Updated Multi-Tenant Commercial Space

Multi-tenant commercial space in downtown Niles, suitable for various businesses.

306 E Main Street, Niles, MI 49120
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Turnkey Industrial Facility on 4.3 Acres
$344,000
6,000 SF

Turnkey Industrial Facility on 4.3 Acres

6,000 SF industrial facility with advanced indoor agriculture setup.

1760 Renaissance Drive, Niles, MI 49120
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Historic Niles Building For Sale
$975,000
11,696 SF

Historic Niles Building For Sale

Downtown Niles building with gym and residential tenants.

115 E Main Street, Niles, MI 49120
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Adaptable Office/Medical Space Near Downtown
$950,000
5,280 SF

Adaptable Office/Medical Space Near Downtown

Updated office/medical space near downtown Niles and the hospital.

122 Grant Street, Niles, MI 49120
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Commercial Property in Niles, MI
$490,000
2,700 SF

Commercial Property in Niles, MI

2,700 SF commercial property with high visibility in Niles.

2229 S 11th Street, Niles, MI 49120
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50 Acres Hunting/Farmland Opportunity
$600,000
50.00 Acres

50 Acres Hunting/Farmland Opportunity

50 acres in Michigan near Indiana border with hunting and farmland.

Portage Road, Niles, MI 49120
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Versatile Commercial Building in Niles
$399,000
3,680 SF

Versatile Commercial Building in Niles

3,600+ sq. ft. commercial building in downtown Niles, MI

920 Lambert Street, Niles, MI 49120
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Versatile Commercial Building in Niles
$399,000
3,600 SF

Versatile Commercial Building in Niles

3,600+ sq. ft. commercial building in downtown Niles, MI.

920 Lambert Street, Niles, MI 49120
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Versatile Commercial Property in Niles
$1,800,000
12,502 SF

Versatile Commercial Property in Niles

Over 12,000 sq ft on 2 acres in Niles Township.

2534 S 11th Street, Niles, MI 49120
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Versatile Industrial Building in Niles
$1,500,000
31,656 SF

Versatile Industrial Building in Niles

31,556 SF industrial building in Niles Industrial Park.

2112 Industrial Drive, Niles, MI 49120
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Commercially Zoned Building in Niles
$129,900
2,430 SF

Commercially Zoned Building in Niles

Commercially zoned building suitable for office, retail, distribution, or storage.

224 N 4th Street, Niles, MI 49120
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Spacious Land Parcel Near Indiana
$1,245,000
1,375 SF

Spacious Land Parcel Near Indiana

67-acre property suitable for development, recreation, or private estate.

32898 Bertrand, Niles, MI 49120
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Commercial Triplex with Drive-Thru Potential
$650,000
5,791 SF

Commercial Triplex with Drive-Thru Potential

Triplex with commercial zoning and drive-thru, near Notre Dame.

2639 S 3rd Street, Niles, MI 49120
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52-Acre Development Opportunity, Niles
$1,100,000
52.67 Acres

52-Acre Development Opportunity, Niles

52-acre parcel for development in a thriving suburban landscape.

Lake Street, Niles, MI 49120
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Sprawling Land Parcel in Niles
$398,200
36.20 Acres

Sprawling Land Parcel in Niles

36.2 acres of land ready for your vision.

V/L Pucker Street, Niles, MI 49120
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Niles Office Building For Sale
$3,400,000
27,377 SF

Niles Office Building For Sale

Office building with 27377 square feet of space.

2100 South 11th Street, Niles, MI 49120
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Niles Township Grow Facility
$495,000
40,000 SF

Niles Township Grow Facility

Grow facility on 4 acres with buildings and greenhouses.

1430 S 3rd Street, Niles, MI 49120
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Redevelopment Opportunity on Corner Lot
$1,200,000
5,840 SF

Redevelopment Opportunity on Corner Lot

1.13 acres available for redevelopment on a stop light corner.

2640 S 11th Street, Niles, MI 49120
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Niles, MI Commercial Real Estate Investment Opportunities Market Analysis

Explore 36 commercial real estate for sale in Niles, MI, showcased through 36 active listings on our real estate platform. These investment opportunities span a total of 10,407,355 square feet of properties for sale, with an estimated market value of $18,334,000.

Sale prices for business properties in Niles, MI start at $129,900, averaging $763,916, and reaching up to $1,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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