Niles, MI Medical Office Space for Sale

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South Bend, IN Buchanan, MI Berrien Center, MI

Updated: Apr 21, 2025

Adaptable Office/Medical Space Near Downtown

122 Grant Street, Niles, MI 49120

$950,000

5,280 sqft · 0.71 AC lot

Over 5,000 sq ft of office/medical space.
Updated in 2016: HVAC, roof, water softeners, parking lot.
Located close to downtown Niles and across the street from the hospital.
Adaptable floor plan with many exam rooms and offices.
Dedicated employee area and bathroom.

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This listing looks promising.

Here's a quick look at some key insights for

122 Grant Street, Niles, MI 49120

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Est. Cap Rate

6.2%
Above avg (5.9%)
Est. NOI

$59K
Annual
Price @ 7% Cap

$841K
Suggested
Property Type

Dental Building
Built 1955

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Updated: Mar 24

Versatile Commercial Building in Niles

920 Lambert Street, Niles, MI 49120

$399,000

3,600 sqft · 0.34 AC lot

Prime downtown Niles location offers high visibility and accessibility.
Versatile 3,600+ sq. ft. building adaptable for various uses.
Currently configured as a medical office with multiple offices and exam rooms.
Ideal for investors or business owners seeking expansion opportunities.
Functional layout designed for optimal flow and efficiency.

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Limestone Office Building with Parking

111 N 4th St, Niles, MI 49120

$200,000

Solid limestone downtown office building with central air and gas heat, plus space behind for additional parking.

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Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 3 Active listings in Niles, MI, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 25 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Versatile Medical and Office Building

806 N Orchard Street, Dowagiac, MI 49047

$199,000

4,238 sqft · 0.20 AC lot

Flexible office and service layout with private offices, kitchen area, and three restrooms, plus ample parking.

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Flexible Office and Wellness Facility

806 N Orchard St, Dowagiac, MI 49047

$199,000

Versatile multi-restroom office space with private offices and open work areas, suited for office, service, or wellness uses.

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Mishawaka Medical Office Investment Opportunity

3730 Edison Lakes Pkwy, Mishawaka, IN

$888,659

6,706 sqft · 1.22 AC lot

Leased medical office space with long-term tenant commitment.

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Downtown Mishawaka Office Space Available

303 N Main St, Mishawaka, IN 46544

Contact for pricing

Office building centrally located near new construction and river walk.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Near I-94

3886 N 950 W, Michigan City, IN 46360

$350,000

5.58 AC lot

5.38 acres of commercial land in Michigan City, Indiana.

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Valparaiso Land Parcel For Sale

2601 Leonard Dr, Valparaiso, IN 46383

$395,000

4.00 AC lot

4-acre Valparaiso land parcel suitable for medical or assembly.

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Valparaiso, IN Commercial Land

2500 Cumberland Drive, Valparaiso, IN 46383

$227,383

1.00 AC lot

One-acre commercial lot in a premium, fully developed location.

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Valparaiso Commercial Land For Sale

1465 Clark Road, Valparaiso, IN 46385

$284,900

1.23 AC lot

Commercial land on State Highway 2, near Highway 30.

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Off-Market Properties in Niles, MI

Consider similar Off-Market properties in Niles, MI. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

DENTAL BUILDING

8 Saint Joseph Ave, Niles, MI 49120-2214

Value Estimation by Request

19,050 sqft · 1.72 AC lot

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DENTAL BUILDING

115 Saint Joseph Ave, Niles, MI 49120-2848

Value Estimation by Request

1,948 sqft · 0.20 AC lot

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DENTAL BUILDING

2753 11th St, Niles, MI 49120-4419

Value Estimation by Request

4,480 sqft · 1.12 AC lot

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DENTAL BUILDING

109 Lincoln Ave, Niles, MI 49120-2917

Value Estimation by Request

2,184 sqft · 0.29 AC lot

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MEDICAL CLINIC

16 Saint Joseph Ave, Niles, MI 49120-2847

Value Estimation by Request

1,800 sqft · 0.20 AC lot

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DENTAL BUILDING

315 Main St, Niles, MI 49120-2365

Value Estimation by Request

5,560 sqft · 0.17 AC lot

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DENTAL BUILDING

12 Longmeadow Vlg Dr, Niles, MI 49120-7808

$1,045,000

Estimated value

6,246 sqft · 1.50 AC lot

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MEDICAL CLINIC

207 Cedar St, Niles, MI 49120-2669

Value Estimation by Request

1,056 sqft · 0.04 AC lot

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DENTAL BUILDING

1005 Moore St, Niles, MI 49120

Value Estimation by Request

12,232 sqft · 1.84 AC lot

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DENTAL BUILDING

122 Grant St, Niles, MI 49120-2201

Value Estimation by Request

5,100 sqft · 0.71 AC lot

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MEDICAL CLINIC

104 Grant St, Niles, MI 49120-2201

Value Estimation by Request

2,647 sqft · 0.14 AC lot

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DENTAL BUILDING

60 Saint Joseph Ave, Niles, MI 49120-2296

Value Estimation by Request

5,872 sqft · 0.53 AC lot

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DENTAL BUILDING

8 Longmeadow Vlg Dr, Niles, MI 49120-7808

Value Estimation by Request

8,831 sqft · 1.77 AC lot

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MEDICAL CLINIC

10 State St, Niles, MI 49120-2295

Value Estimation by Request

2,400 sqft · 0.20 AC lot

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DENTAL BUILDING

21 2nd St, Niles, MI 49120-2218

Value Estimation by Request

840 sqft · 0.04 AC lot

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DENTAL BUILDING

9 Saint Joseph Ave, Niles, MI 49120-2846

Value Estimation by Request

3,841 sqft · 0.20 AC lot

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MEDICAL CLINIC

1111 Lambert St, Niles, MI 49120-3439

Value Estimation by Request

3,556 sqft · 1.23 AC lot

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MEDICAL CLINIC

123 Marmont St, Niles, MI 49120-1657

Value Estimation by Request

4,366 sqft · 1.05 AC lot

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DENTAL BUILDING

120 Longmeadow Vlg Dr, Niles, MI 49120-7808

Value Estimation by Request

17,594 sqft · 2.74 AC lot

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Office Units

20 2Nd St, Niles, MI 49120

Value Estimation by Request

View details

Medical Office Space

8 St Joseph Ave, Niles, MI 49120

Value Estimation by Request

19,050 sqft

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Niles, MI Medical Office Space Market Trends and Statistics

Explore 28 medical office space for sale in Niles, MI, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 8,880 square feet of properties for sale, with an estimated market value of $1,349,000.

Sale prices for medical spaces in Niles, MI start at $399,000, averaging $674,500, and reaching up to $950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 37K

Population Growth (5Y) +0.4%

Median Household Income $61,940

College Educated 14.5%

High-Yield Neighborhoods for Investment

Identify Niles submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
49120	$516.3K

Taxes & Financing

Tax Rate (average for all types) 3.49%

Property Tax per SF $64.97 per SF

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Berrien County

New Delisted

Total CRE Inventory on Market (SF)

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Niles, MI Medical Office Space for Sale

122 Grant Street, Niles, MI 49120

920 Lambert Street, Niles, MI 49120

111 N 4th St, Niles, MI 49120

Opportunities in Nearby Cities

806 N Orchard Street, Dowagiac, MI 49047

806 N Orchard St, Dowagiac, MI 49047

3730 Edison Lakes Pkwy, Mishawaka, IN

303 N Main St, Mishawaka, IN 46544

Potential Development Sites for Consideration

3886 N 950 W, Michigan City, IN 46360

2601 Leonard Dr, Valparaiso, IN 46383

2500 Cumberland Drive, Valparaiso, IN 46383

1465 Clark Road, Valparaiso, IN 46385

Off-Market Properties in Niles, MI

8 Saint Joseph Ave, Niles, MI 49120-2214

115 Saint Joseph Ave, Niles, MI 49120-2848

2753 11th St, Niles, MI 49120-4419

109 Lincoln Ave, Niles, MI 49120-2917

16 Saint Joseph Ave, Niles, MI 49120-2847

315 Main St, Niles, MI 49120-2365

12 Longmeadow Vlg Dr, Niles, MI 49120-7808

207 Cedar St, Niles, MI 49120-2669

1005 Moore St, Niles, MI 49120

122 Grant St, Niles, MI 49120-2201

104 Grant St, Niles, MI 49120-2201

60 Saint Joseph Ave, Niles, MI 49120-2296

8 Longmeadow Vlg Dr, Niles, MI 49120-7808

10 State St, Niles, MI 49120-2295

21 2nd St, Niles, MI 49120-2218

9 Saint Joseph Ave, Niles, MI 49120-2846

1111 Lambert St, Niles, MI 49120-3439

123 Marmont St, Niles, MI 49120-1657

120 Longmeadow Vlg Dr, Niles, MI 49120-7808

20 2Nd St, Niles, MI 49120

8 St Joseph Ave, Niles, MI 49120

Niles, MI Medical Office Space Market Trends and Statistics

Top Commercial Asset Segments

Demographics Overview

High-Yield Neighborhoods for Investment

Taxes & Financing

Listings Trend

Total CRE Inventory on Market (SF)

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