Medical Premises

Niles, MI Medical Office Space for Sale

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Updated Office and Medical Building
Updated: Apr 21, 2025
Updated Office and Medical Building

122 Grant Street, Niles, MI 49120

$925,000
5,280 sqft 0.71 AC lot
Over 5,000 sq ft office/medical space close to downtown Niles and across from the hospital
Updated in 2016 with HVAC, roof, water softeners, and parking lot
Forced air heat and central air conditioning
Large basement for additional storage
Many exam rooms and offices with an adaptable floor plan
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122 Grant Street, Niles, MI 49120

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Office and Medical Space Building
Updated: Jul 10
Office and Medical Space Building

122 Grant Street, Niles, MI 49120

$925,000
5,000 sqft
Updated 5,280 SF office/medical building with exam rooms and offices on a single 1‑story structure
Across the street from the hospital and close to downtown Niles
Updates in 2016 include HVAC, roof, water softeners, and the parking lot
3 total baths with heating and air conditioning (both yes)
Basement included, offering ample storage space plus a dedicated employee area and bathroom
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Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 2 Active listings in Niles, MI, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 25 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

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Medical Office Space with Exam Rooms

302 Front Street, Dowagiac, MI 49047

Contact for pricing
1,800 sqft

Flexible professional suite with reception, private rooms, restrooms, kitchen, and laundry area in downtown Dowagiac.

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Flexible Office and Wellness Facility
Flexible Office and Wellness Facility

806 N Orchard St, Dowagiac, MI 49047

$199,000

Versatile multi-restroom office space with private offices and open work areas, suited for office, service, or wellness uses.

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Net Leased Physical Therapy Building
Net Leased Physical Therapy Building

221 W Day Rd, Mishawaka, IN 46545

Contact for pricing
2,563 sqft

Single-tenant ATI Physical Therapy property with a drive-thru window and a remaining primary lease term.

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Mishawaka Medical Office Investment Opportunity
Mishawaka Medical Office Investment Opportunity

3730 Edison Lakes Pkwy, Mishawaka, IN

Contact for pricing
6,706 sqft 1.22 AC lot

Leased medical office space with long-term tenant commitment.

View details

Off-Market Properties in Niles, MI

Consider similar Off-Market properties in Niles, MI. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

8 Saint Joseph Ave
DENTAL BUILDING

8 Saint Joseph Ave, Niles, MI 49120-2214

$690,000
Estimated value
19,050 sqft 1.72 AC lot
View details
115 Saint Joseph Ave
DENTAL BUILDING

115 Saint Joseph Ave, Niles, MI 49120-2848

$365,000
Estimated value
1,948 sqft 0.20 AC lot
View details
2753 11th St
DENTAL BUILDING

2753 11th St, Niles, MI 49120-4419

$635,000
Estimated value
4,480 sqft 1.12 AC lot
View details
109 Lincoln Ave
DENTAL BUILDING

109 Lincoln Ave, Niles, MI 49120-2917

$135,000
Estimated value
2,184 sqft 0.29 AC lot
View details
16 Saint Joseph Ave
MEDICAL CLINIC

16 Saint Joseph Ave, Niles, MI 49120-2847

$125,000
Estimated value
1,800 sqft 0.20 AC lot
View details
315 Main St
DENTAL BUILDING

315 Main St, Niles, MI 49120-2365

$375,000
Estimated value
5,560 sqft 0.17 AC lot
View details
12 Longmeadow Vlg Dr
DENTAL BUILDING

12 Longmeadow Vlg Dr, Niles, MI 49120-7808

$1,105,000
Estimated value
6,246 sqft 1.50 AC lot
View details
207 Cedar St
MEDICAL CLINIC

207 Cedar St, Niles, MI 49120-2669

$220,000
Estimated value
1,056 sqft 0.04 AC lot
View details
1005 Moore St
DENTAL BUILDING

1005 Moore St, Niles, MI 49120

Value Estimation by Request
12,232 sqft 1.84 AC lot
View details
122 Grant St
DENTAL BUILDING

122 Grant St, Niles, MI 49120-2201

Value Estimation by Request
5,100 sqft 0.71 AC lot
View details
104 Grant St
MEDICAL CLINIC

104 Grant St, Niles, MI 49120-2201

$365,000
Estimated value
2,647 sqft 0.14 AC lot
View details
60 Saint Joseph Ave
DENTAL BUILDING

60 Saint Joseph Ave, Niles, MI 49120-2296

$560,000
Estimated value
5,872 sqft 0.53 AC lot
View details
8 Longmeadow Vlg Dr
DENTAL BUILDING

8 Longmeadow Vlg Dr, Niles, MI 49120-7808

$360,000
Estimated value
8,831 sqft 1.77 AC lot
View details
10 State St
MEDICAL CLINIC

10 State St, Niles, MI 49120-2295

$245,000
Estimated value
2,400 sqft 0.20 AC lot
View details
21 2nd St
DENTAL BUILDING

21 2nd St, Niles, MI 49120-2218

$55,000
Estimated value
840 sqft 0.04 AC lot
View details
9 Saint Joseph Ave
DENTAL BUILDING

9 Saint Joseph Ave, Niles, MI 49120-2846

$270,000
Estimated value
3,841 sqft 0.20 AC lot
View details
1111 Lambert St
MEDICAL CLINIC

1111 Lambert St, Niles, MI 49120-3439

Value Estimation by Request
3,556 sqft 1.23 AC lot
View details
123 Marmont St
MEDICAL CLINIC

123 Marmont St, Niles, MI 49120-1657

Value Estimation by Request
4,366 sqft 1.05 AC lot
View details
120 Longmeadow Vlg Dr
DENTAL BUILDING

120 Longmeadow Vlg Dr, Niles, MI 49120-7808

$635,000
Estimated value
17,594 sqft 2.74 AC lot
View details
20 2Nd St
Office Units

20 2Nd St, Niles, MI 49120

Value Estimation by Request
View details
8 St Joseph Ave
Medical Office Space

8 St Joseph Ave, Niles, MI 49120

Value Estimation by Request
19,050 sqft
View details
2 Saint Joseph Ave
DENTAL BUILDING

2 Saint Joseph Ave, Niles, MI 49120-2214

$370,000
Estimated value
2,703 sqft 0.12 AC lot
View details

Niles, MI Medical Office Space Market Trends and Statistics

Explore 27 medical office space for sale in Niles, MI on our real estate platform. These investment opportunities span a total of 10,280 square feet of properties for sale, with an estimated market value of $1,850,000.

Sale prices for medical spaces in Niles, MI average $925,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office buildings 7
Office Units 6
Medical Office Space 4
Creative space 2
Coworking space 1

Demographics Overview

Population 37K
Population Growth (5Y) +0.4%
Median Household Income $61,940
College Educated 14.5%

High-Yield Neighborhoods for Investment

Identify Niles submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
49120 $691.7K

Taxes & Financing

Tax Rate (average for all types) 3.49%
Property Tax per SF $64.97 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Berrien County

New Delisted

Total CRE Inventory on Market (SF)

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