Medical Premises

Niles, MI Medical Office Space for Sale

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Updated Medical Office Building
Updated: Apr 21, 2025
Updated Medical Office Building

122 Grant Street, Niles, MI 49120

$925,000
5,280 sqft 0.71 AC lot
5,280 square feet of office and medical space
0.71‑acre site at 122 Grant Street, Niles, MI 49120
Updated in 2016 with HVAC, roof, water softeners, and parking lot improvements
Multiple exam rooms and offices support an adaptable floor plan
Large basement, employee area, and three bathrooms
View details
Downtown Limestone Office Building
Updated: Sep 22
Downtown Limestone Office Building

111 N 4th St, Niles, MI 49120

$99,000
1,270 sqft
1,270 SF limestone office building
50 feet of road frontage
Located in Niles’ central downtown business district
Central air conditioning and gas heat
Built in 1949
View details
See hot listings in Niles

Scored against comparables nationwide. These are worth a look.

Scored against comparables nationwide. These are worth a look.

Cap Rate available after sign in
Est. NOI available after sign in
Local Demand available after sign in
Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 2 Active listings in Niles, MI, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 25 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Medical Office Suite with New HVAC
Medical Office Suite with New HVAC

St Joseph, MI 49085

$311,000
2,046 sqft

Configured with reception, waiting areas, multiple offices, and two bathrooms.

View details
Move-In-Ready Medical Office Suite
Move-In-Ready Medical Office Suite

St Joseph, MI 49085

Contact for pricing
3,220 sqft

Medical suite in an office park with on-site parking and monument signage near I-94.

View details
Medical Office Building
Medical Office Building

6915 N Fir Rd, Mishawaka, IN 46530

Contact for pricing
7,841 sqft 2.00 AC lot

Modern commercial property with a built medical suite and contiguous space for expansion or separate occupancy.

View details
Mishawaka Medical Office Investment Opportunity
Mishawaka Medical Office Investment Opportunity

3730 Edison Lakes Pkwy, Mishawaka, IN

Contact for pricing
6,706 sqft 1.22 AC lot

Leased medical office space with long-term tenant commitment.

View details

Off-Market Properties in Niles, MI

Consider similar Off-Market properties in Niles, MI. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

8 Saint Joseph Ave
DENTAL BUILDING

8 Saint Joseph Ave, Niles, MI 49120-2214

Estimated value:
$690,000
19,050 sqft 1.72 AC lot
View details
115 Saint Joseph Ave
DENTAL BUILDING

115 Saint Joseph Ave, Niles, MI 49120-2848

Estimated value:
$365,000
1,948 sqft 0.20 AC lot
View details
2753 11th St
DENTAL BUILDING

2753 11th St, Niles, MI 49120-4419

Estimated value:
$635,000
4,480 sqft 1.12 AC lot
View details
109 Lincoln Ave
DENTAL BUILDING

109 Lincoln Ave, Niles, MI 49120-2917

Estimated value:
$135,000
2,184 sqft 0.29 AC lot
View details
16 Saint Joseph Ave
MEDICAL CLINIC

16 Saint Joseph Ave, Niles, MI 49120-2847

Estimated value:
$125,000
1,800 sqft 0.20 AC lot
View details
315 Main St
DENTAL BUILDING

315 Main St, Niles, MI 49120-2365

Estimated value:
$375,000
5,560 sqft 0.17 AC lot
View details
12 Longmeadow Vlg Dr
DENTAL BUILDING

12 Longmeadow Vlg Dr, Niles, MI 49120-7808

Estimated value:
$1,105,000
6,246 sqft 1.50 AC lot
View details
207 Cedar St
MEDICAL CLINIC

207 Cedar St, Niles, MI 49120-2669

Estimated value:
$220,000
1,056 sqft 0.04 AC lot
View details
1005 Moore St
DENTAL BUILDING

1005 Moore St, Niles, MI 49120

Estimated value: by Request
12,232 sqft 1.84 AC lot
View details
122 Grant St
DENTAL BUILDING

122 Grant St, Niles, MI 49120-2201

Estimated value: by Request
5,100 sqft 0.71 AC lot
View details
104 Grant St
MEDICAL CLINIC

104 Grant St, Niles, MI 49120-2201

Estimated value:
$365,000
2,647 sqft 0.14 AC lot
View details
60 Saint Joseph Ave
DENTAL BUILDING

60 Saint Joseph Ave, Niles, MI 49120-2296

Estimated value:
$560,000
5,872 sqft 0.53 AC lot
View details
8 Longmeadow Vlg Dr
DENTAL BUILDING

8 Longmeadow Vlg Dr, Niles, MI 49120-7808

Estimated value:
$360,000
8,831 sqft 1.77 AC lot
View details
10 State St
MEDICAL CLINIC

10 State St, Niles, MI 49120-2295

Estimated value:
$245,000
2,400 sqft 0.20 AC lot
View details
21 2nd St
DENTAL BUILDING

21 2nd St, Niles, MI 49120-2218

Estimated value:
$55,000
840 sqft 0.04 AC lot
View details
9 Saint Joseph Ave
DENTAL BUILDING

9 Saint Joseph Ave, Niles, MI 49120-2846

Estimated value:
$270,000
3,841 sqft 0.20 AC lot
View details
1111 Lambert St
MEDICAL CLINIC

1111 Lambert St, Niles, MI 49120-3439

Estimated value: by Request
3,556 sqft 1.23 AC lot
View details
123 Marmont St
MEDICAL CLINIC

123 Marmont St, Niles, MI 49120-1657

Estimated value: by Request
4,366 sqft 1.05 AC lot
View details
120 Longmeadow Vlg Dr
DENTAL BUILDING

120 Longmeadow Vlg Dr, Niles, MI 49120-7808

Estimated value:
$635,000
17,594 sqft 2.74 AC lot
View details
2 Saint Joseph Ave
DENTAL BUILDING

2 Saint Joseph Ave, Niles, MI 49120-2214

Estimated value:
$370,000
2,703 sqft 0.12 AC lot
View details

Niles, MI Medical Office Space Market Trends and Statistics

Explore 27 medical office space for sale in Niles, MI on our real estate platform. These investment opportunities span a total of 6,550 square feet of properties for sale, with an estimated market value of $1,024,000.

Sale prices for medical spaces in Niles, MI start at $99,000, averaging $512,000, and reaching up to $925,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 5
Medical Office Space 3
Office buildings 3
Creative space 1

Demographics Overview

Population 37K
Population Growth (5Y) +0.4%
Median Household Income $61,940
College Educated 14.5%

High-Yield Neighborhoods for Investment

Identify Niles submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
49120 $512K

Taxes & Financing

Tax Rate (average for all types) 3.49%
Property Tax per SF $64.97 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Berrien County

New Delisted

Total CRE Inventory on Market (SF)

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