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    Guadalupe County, TX Commercial Real Estate for Sale

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    Houston, TX San Antonio, TX Dallas, TX
    208 results
    Historic Seguin Building with Charm
    $898,000
    4,954 SF

    Historic Seguin Building with Charm

    204 S Austin Street, Seguin, TX 78155

    Prime downtown location suitable for bar, restaurant, or office.

    • Prime downtown location on South Austin Street with excellent visibility.
    • Historical charm with exposed brick walls, high ceilings, and large windows.
    • Open concept floor plan provides flexible interior design options.
    • Private desk spaces with balcony overlooking Austin Street.
    • Conference room that can be repurposed.
    Updated: Feb 20
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    Prime Location in McQueeney, Texas
    $569,600
    2,864 SF

    Prime Location in McQueeney, Texas

    4004 Fm 78, Mcqueeney, TX 78123

    High-traffic commercial property with multiple income streams in McQueeney, TX.

    • Prime location at the intersection of FM 725 and FM 78 in McQueeney, Texas
    • High‑traffic location between Seguin and San Antonio
    • Almost three‑quarters of an acre of land
    • Existing business with bar, taco truck, and fireworks sales
    • Additional pad site available for a vendor
    Updated: Dec 7, 2025
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    Seguin Warehouse with Yard Space
    $650,000
    4,000 SF

    Seguin Warehouse with Yard Space

    Climate-controlled shop/warehouse on 5.5 acres near Seguin, Texas.

    140 Thunderbird Lane, Seguin, TX 78155
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    Live/Work Property with Commercial Zoning
    $699,900
    2,368 SF

    Live/Work Property with Commercial Zoning

    2.4 acre property with commercial zoning and living accommodations.

    5037 N State Highway 123, Seguin, TX 78155
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    Charming 1930s Mixed-Use Property
    $159,000
    1,366 SF

    Charming 1930s Mixed-Use Property

    Unique fixer-upper with residential or commercial potential in Marion, TX.

    517 Center St, Marion, TX 78124
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    44.94 Acres Near Seguin
    $700,000
    44.94 Acres

    44.94 Acres Near Seguin

    Prime land tract with development potential near Hwy 123.

    3141 Zion Hill, Seguin, TX 78155
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    Historic Clemens School Event Venue
    $475,000
    3,319 SF

    Historic Clemens School Event Venue

    Unique commercial venue, ideal for events and gatherings.

    7390 Gin Road, Marion, TX 78124
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    Seguin Landmark Commercial Building
    $1,400,000
    10,850 SF

    Seguin Landmark Commercial Building

    Iconic building suitable for various uses on a corner lot.

    1308 N Bowie Street, Seguin, TX 78155
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    Prime Land in Selma, TX
    $700,000
    1,520 SF

    Prime Land in Selma, TX

    4 acres of land suitable for mixed-use development.

    16874 Lookout, Selma, TX 78154
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    30 Acres Development Opportunity, Seguin
    $900,000
    30.88 Acres

    30 Acres Development Opportunity, Seguin

    30-acre tract in Marion ISD with no restrictions.

    S Santa Clara Road, Seguin, TX 78155
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    Commercial Land on Interstate 10
    $2,300,000
    8.28 Acres

    Commercial Land on Interstate 10

    8.29 acres of commercial land in Seguin, Texas.

    Sunbelt Loop lot: 6, Seguin, TX 78155
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    Selma, TX Multifamily Development
    $3,900,000
    17,100 SF

    Selma, TX Multifamily Development

    Partially complete multifamily development with high potential in Selma, TX.

    16800 LOOKOUT RD, Selma, TX 78154
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    Seguin Commercial Land I-10 Corner
    $2,300,000
    8.28 Acres

    Seguin Commercial Land I-10 Corner

    8.29 acre commercial land at I-10 and Highway 90.

    Sunbelt Loop, Seguin, TX 78155
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    8.25 Acres on FM 775
    $350,000
    8.25 Acres

    8.25 Acres on FM 775

    8.25 acres near Seguin, TX with commercial potential.

    Fm 775, Seguin, TX 78155
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    Seguin Warehouse with High Ceilings
    $1,100,000
    11,000 SF

    Seguin Warehouse with High Ceilings

    11,000 sq ft warehouse near I-10 in Seguin.

    1127 N Bowie, Seguin, TX 78155
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    Downtown Seguin Commercial Real Estate
    $2,400,000
    18,960 SF

    Downtown Seguin Commercial Real Estate

    Full block of commercial real estate in downtown Seguin.

    256 W Court Street, Seguin, TX 78155
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    Unrestricted Land in Marion, TX
    $300,000
    6.04 Acres

    Unrestricted Land in Marion, TX

    6.037 acres of unrestricted land with existing utilities.

    3171 Lower Seguin, Marion, TX 78124
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    Cleared Land Near Seguin, TX
    $575,000
    14.81 Acres

    Cleared Land Near Seguin, TX

    14.812 acres of cleared land suitable for multiple uses.

    FM 775, Seguin, TX 78155
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    Land Near Downtown Seguin
    $150,000
    2.70 Acres

    Land Near Downtown Seguin

    2.7 acres close to downtown and Starke Park.

    Sutherland Springs, Seguin, TX 78155
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    Seguin Commercial Property For Sale
    $975,000
    12,600 SF

    Seguin Commercial Property For Sale

    12,600 SF commercial property in Seguin, Texas, for sale.

    5440 S Highway 123 Bypass, Seguin, TX 78155
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    Manageable Seguin Ranch Land
    $480,000
    24.00 Acres

    Manageable Seguin Ranch Land

    24-acre ranch land with agricultural infrastructure in Seguin, Texas.

    332 - 1 FM 2438, Seguin, TX 78155
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    Prime Commercial Lot Near IH10
    $325,000
    1.22 Acres

    Prime Commercial Lot Near IH10

    1.2 acre commercial corner lot near IH10 in Seguin, TX.

    N Austin Street, Seguin, TX 78155
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    Land Tracts in Seguin, TX
    $395,000
    10.82 Acres

    Land Tracts in Seguin, TX

    Land tracts featuring riverfront and rolling countryside in East Seguin.

    10.86 Acres Tract 4 Village Lane, Seguin, TX 78155
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    Unrestricted Land Near Seguin, TX
    $442,000
    34.40 Acres

    Unrestricted Land Near Seguin, TX

    34.4 acres of unrestricted land ready for your dream home.

    12504 Fm 1117, Seguin, TX 78155
    View details

    Guadalupe County, TX Commercial Real Estate Investment Opportunities Market Analysis

    Explore 3196 commercial real estate for sale in Guadalupe County, TX, showcased through 208 active listings on our real estate platform. These investment opportunities span a total of 1,596,568 square feet of properties for sale, with an estimated market value of $126,120,677.

    Sale prices for business properties in Guadalupe County, TX start at $159,000, averaging $2,335,568, and reaching up to $24,053,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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