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Guadalupe County, TX Mixed-use Properties for Sale

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8 results
Live/Work Property with Commercial Zoning
$699,900
2,368 SF

Live/Work Property with Commercial Zoning

5037 N State Highway 123, Seguin, TX 78155

2.4 acre property with commercial zoning and living accommodations.

  • Prime Location: High traffic area on the north side of Seguin, close to Navarro High School, with easy access to IH10, Hwy 46, and IH35.
  • Commercial Zoning: Front half of the 2.4‑acre tract is zoned for commercial use, ideal for a live/work setup or business development.
  • Owner Financing: Owner financing is available.
  • Income Potential: Includes a 1/1 apartment, providing rental income opportunities.
  • Outdoor Amenities: Features a swimming pool, 22 x 54 covered entertaining area, screened‑in porch, oversized carport, and gated access.
Updated: Feb 9
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Prime Land in Selma, TX
$700,000
1,520 SF

Prime Land in Selma, TX

16874 Lookout, Selma, TX 78154

4 acres of land suitable for mixed-use development.

  • Seller financing available.
  • Prime location at the hard corner of Lookout & Evans Rd in a high‑traffic, rapidly growing area.
  • City utilities are already on site.
  • Proximity to the new University Baptist Hospital and planned luxury MF/retail complex.
  • Approved for multiple uses by the City of Selma, including MF, retail, mixed‑use, industrial, flex space, and hospitality.
Updated: Dec 16, 2025
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Downtown Seguin Commercial Real Estate
$2,400,000
18,960 SF

Downtown Seguin Commercial Real Estate

Full block of commercial real estate in downtown Seguin.

256 W Court Street, Seguin, TX 78155
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Historic Downtown Seguin Commercial Building
$969,000
6,554 SF

Historic Downtown Seguin Commercial Building

Two-story commercial building in historic downtown Seguin with many possibilities.

109 N River Street, Seguin, TX 78155
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Mixed-Use Block Assemblage with Parking
$2,400,000
18,960 SF

Mixed-Use Block Assemblage with Parking

Mixed-use property with retail, office, warehouse, and parking.

256 W Court St, Seguin, TX 78155
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FM 78 Commercial Opportunity
$1,599,000
2,438 SF

FM 78 Commercial Opportunity

Historic property with high visibility and multiple access points.

505 FM78, Cibolo, TX 78108
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Prime Corner Lot Opportunity
$2,000,000

Prime Corner Lot Opportunity

6-acre corner lot suitable for mixed-use development.

16874 Lookout Rd, Schertz, TX 78154
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Historic Downtown Seguin Commercial Portfolio
$1,135,700
5,476 SF

Historic Downtown Seguin Commercial Portfolio

Retail and office spaces in historic downtown Seguin.

200 E Court St, Seguin, TX 78155
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Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 8 Active listings in Guadalupe County, TX, we suggest exploring several alternatives: similar 11 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

30 Acres Development Opportunity, Seguin
$900,000
30.88 Acres

30 Acres Development Opportunity, Seguin

30-acre tract in Marion ISD with no restrictions.

S Santa Clara Road, Seguin, TX 78155
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New Braunfels Land For Sale
$1,199,999
2.50 Acres

New Braunfels Land For Sale

2.49-acre property near the heart of New Braunfels, Texas.

S Seguin Ave, New Braunfels, TX 78130
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Prime Land in New Braunfels
$1,199,999
2.50 Acres

Prime Land in New Braunfels

2.49 acres with FM-725 frontage near I-35.

S Seguin Ave., New Braunfels, TX 78130
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11.25 Acres of Land
Contact for pricing

11.25 Acres of Land

11.25 acres of land available for sale.

451 FM306, New Braunfels, TX 78130
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Explore Off-Market Properties in Guadalupe County, TX

Consider similar Off-Market properties in Guadalupe County, TX. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

1807 Fm 758

1807 Fm 758

Lifestyle centers • 1,596 SF
Value Estimation by Request
1807 Fm 758, New Braunfels, TX 78130
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971 Schriewer St

971 Schriewer St

Office Units • 5,000 SF
Value Estimation by Request
971 Schriewer St, Seguin, TX 78155
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1807 New Braunfels Tx 78130

1807 New Braunfels Tx 78130

Lifestyle centers • 1,596 SF
Value Estimation by Request
1807 New Braunfels Tx 78130, New Braunfels, TX 78130
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316 Castin Ln

316 Castin Ln

Multifamily properties • 4,000 SF
Value Estimation by Request
316 Castin Ln, New Braunfels, TX 78130
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Tx-123

Tx-123

Day care centers • 17.19 Acres
Value Estimation by Request
0 Tx-123, San Marcos, TX 78666
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1807 Farm To Market Rd

1807 Farm To Market Rd

Lifestyle centers • 1,596 SF
Value Estimation by Request
1807 Farm To Market Rd, New Braunfels, TX 78130
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1535 Guadalupe St

1535 Guadalupe St

Self storage facilities
Value Estimation by Request
1535 Guadalupe St, Seguin, TX 78155
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200 Court St

200 Court St

Restaurants • 5,476 SF
Value Estimation by Request
200 Court St, Seguin, TX 78155
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355 Pine Meadow Rd

355 Pine Meadow Rd

Flex space • 102.00 Acres
Value Estimation by Request
355 Pine Meadow Rd, Seguin, TX 78155
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3400 Farm-To-Market Rd

3400 Farm-To-Market Rd

Automotive properties • 4,400 SF
Value Estimation by Request
3400 Farm-To-Market Rd, McQueeney, TX 78123
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Sh-123 & Stremple Rd

Sh-123 & Stremple Rd

Multifamily properties • 44.76 Acres
Value Estimation by Request
0 Sh-123 & Stremple Rd, Seguin, TX 78155
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Guadalupe County, TX Mixed-Use Properties Investment Opportunities Market Analysis

Explore 19 mixed-use properties for sale in Guadalupe County, TX, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 4,876,063 square feet of properties for sale, with an estimated market value of $5,124,000.

Sale prices for multi use buildings in Guadalupe County, TX start at $700,000, averaging $1,281,000, and reaching up to $2,400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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