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    Guadalupe County, TX Commercial Real Estate for Lease

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    Houston, TX Dallas, TX San Antonio, TX
    106 results
    Seguin Commercial Flex Space Available
    $1,395/Mo
    1,250 SF

    Seguin Commercial Flex Space Available

    1419 Fleming Drive, Seguin, TX 78155

    1,250 sq ft flex space near I-10 & Hwy 90.

    • Versatile 1,250 sq ft space suitable for storage, warehouse, workshop, office, or man cave.
    • Convenient location in a 10‑unit warehouse park near I‑10 & Hwy 90.
    • Features an office, large customizable open space, 14‑foot roll‑up garage door, and private bathroom.
    • Includes 4 dedicated parking spots with direct access off Fleming Drive.
    • Owner covers property tax, building insurance, and public area maintenance.
    Updated: Apr 1
    View details
    Downtown Seguin Loft/Workspace for Rent
    $1,500/Mo
    1,254 SF

    Downtown Seguin Loft/Workspace for Rent

    103 W Walnut Street, Seguin, TX 78155

    Urban-style loft/workspace in the heart of downtown Seguin.

    • Prime downtown Seguin location, two blocks from the square.
    • 1,254 sq ft open‑concept loft/workspace.
    • Abundant natural light from expansive windows.
    • Soaring ceilings.
    • Central heating and air conditioning.
    Updated: Apr 28
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    Prime Commercial Space in Seguin
    $2,500/Mo
    1,200 SF

    Prime Commercial Space in Seguin

    Updated 1,200 SF commercial space in downtown Seguin.

    211 E Court Street, Seguin, TX 78155
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    Commercial Space Near Downtown Seguin
    $2,000/Mo
    3,000 SF

    Commercial Space Near Downtown Seguin

    Commercial space for lease near downtown Seguin, Texas.

    637 W Court Street, Seguin, TX 78155
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    Renovated Commercial Space Available
    $1,595/Mo
    1,565 SF

    Renovated Commercial Space Available

    Renovated commercial space with original hardwood floors, available April 2026.

    1427 N Austin Street, Seguin, TX 78155
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    Seguin Commercial Shop on Acreage
    $3,200/Mo
    1,856 SF

    Seguin Commercial Shop on Acreage

    Spacious shop on 5 acres, ideal for various business uses.

    1758 Ilka Switch, Seguin, TX 78155
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    Commercial Building in Seguin, Texas
    $2,800/Mo
    2,250 SF

    Commercial Building in Seguin, Texas

    Functional commercial building with drive-up parking available for rent.

    410 E Gonzales Street, Seguin, TX 78155
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    Office Space Near Downtown Seguin
    $800/Mo
    4,554 SF

    Office Space Near Downtown Seguin

    Office space available in Seguin, Texas, near downtown.

    314 N Austin Street, Seguin, TX 78155
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    Seguin Warehouse Space Available
    $6,500/Mo
    14,591 SF

    Seguin Warehouse Space Available

    7,203 SF warehouse space for lease in Seguin, TX.

    232 W New Braunfels Street, Seguin, TX 78155
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    Highway Frontage Commercial Space
    $1,250/Mo
    6,750 SF

    Highway Frontage Commercial Space

    Commercial space for lease with high traffic and visibility.

    2331 N State Highway 46, Seguin, TX 78155
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    Move-in Ready Commercial Space
    $1,500/Mo
    5,400 SF

    Move-in Ready Commercial Space

    Commercial space near Guadalupe Regional Medical Center in Seguin, TX.

    412 N King Street, Seguin, TX 78155
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    Adaptable Commercial Building in Seguin
    $30 SF/Yr
    13,026 SF

    Adaptable Commercial Building in Seguin

    Well-maintained commercial building in high-traffic area, ideal for business.

    936 S Highway 123 Bypass, Seguin, TX 78155
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    Office and Warehouse Building Available
    $4,500/Mo
    16,555 SF

    Office and Warehouse Building Available

    16,555 sq ft office/warehouse on 2.61 acres.

    1012 Schriewer, Seguin, TX 78155
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    Renovated Commercial Space Available
    Contact for pricing
    1,565 SF

    Renovated Commercial Space Available

    Renovated retail/office/flex space with original hardwood floors.

    1427 N Austin St, Seguin, TX 78155
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    Downtown Seguin Retail Space Available
    $5,241/Mo
    3,276 SF

    Downtown Seguin Retail Space Available

    Shell space in downtown Seguin near Central Park.

    200 E Court Street, Seguin, TX 78155
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    Warehouse with Office and Parking
    Contact for pricing
    3,200 SF

    Warehouse with Office and Parking

    3200 sqft warehouse with office, roll-up doors, ample parking.

    384 Partnership, Seguin, TX 78155
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    Seguin Warehouse Space Available
    Contact for pricing
    7,203 SF

    Seguin Warehouse Space Available

    7,203 SF warehouse space with climate control and easy access.

    232 W New Braunfels St W1-W2, Seguin, TX 78155
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    Seguin Warehouse Space Available
    Contact for pricing
    7,203 SF

    Seguin Warehouse Space Available

    7,203 SF warehouse space for lease in Seguin, TX.

    200-232 W New Braunfels St W1 - W2, Seguin, TX 78155
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    Seguin Office Space For Rent
    $3,800/Mo
    2,442 SF

    Seguin Office Space For Rent

    Office space available on IH 10 in Seguin, TX.

    3040 W Interstate 10 Expressway, Seguin, TX 78155
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    Versatile Commercial Leasing Opportunity
    $0.95 SF/Yr
    9,000 SF

    Versatile Commercial Leasing Opportunity

    Premier commercial complex with flexible build-out options and ample yard space.

    7049 FM 1044, Marion, TX 78124
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    Commercial Building with Drive-Up Parking
    $2,800/Mo

    Commercial Building with Drive-Up Parking

    Functional commercial building with drive-up parking available for rent.

    410 E Gonzales St, Seguin, TX 78155
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    Office Space Near Downtown Seguin
    $800/Mo

    Office Space Near Downtown Seguin

    Office space available in building near downtown Seguin, Texas.

    314 N Austin St, Seguin, TX 78155
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    Prime Retail Space in Seguin
    $2,500/Mo
    1,200 SF

    Prime Retail Space in Seguin

    1,200 SF commercial space in downtown Seguin for lease.

    211 E Court St, Seguin, TX 78155
    View details
    Seguin Office Space For Rent
    $6 SF/Yr
    5,000 SF

    Seguin Office Space For Rent

    Opportunity to build out space to tenant desires.

    1115 N Bowie Street, Seguin, TX 78155
    View details

    Guadalupe County, TX Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Guadalupe County, TX with 106 listings featured on our commercial real estate exchange. The current inventory includes 218,488 square feet of properties with an estimated lease value of $402 /Mo.

    Estimated lease rates for Commercial real estate in Guadalupe County, TX begin at $0.95 SF/Yr, with an average of $11 SF/Yr and extend to $33 SF/Yr.
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