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    Guadalupe County, TX Office Properties & Spaces for Lease

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    Houston, TX Dallas, TX San Antonio, TX
    32 results
    Seguin Commercial Flex Space Available
    $1,395/Mo
    1,250 SF

    Seguin Commercial Flex Space Available

    1419 Fleming Drive, Seguin, TX 78155

    1,250 sq ft flex space near I-10 & Hwy 90.

    • Versatile 1,250 sq ft space suitable for storage, warehouse, workshop, office, or man cave.
    • Convenient location in a 10‑unit warehouse park near I‑10 & Hwy 90.
    • Features an office, large customizable open space, 14‑foot roll‑up garage door, and private bathroom.
    • Includes 4 dedicated parking spots with direct access off Fleming Drive.
    • Owner covers property tax, building insurance, and public area maintenance.
    Updated: Apr 1
    View details
    Downtown Seguin Loft/Workspace for Rent
    $1,500/Mo
    1,254 SF

    Downtown Seguin Loft/Workspace for Rent

    103 W Walnut Street, Seguin, TX 78155

    Urban-style loft/workspace in the heart of downtown Seguin.

    • Prime downtown Seguin location, two blocks from the square.
    • 1,254 sq ft open‑concept loft/workspace.
    • Abundant natural light from expansive windows.
    • Soaring ceilings.
    • Central heating and air conditioning.
    Updated: Apr 28
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    Prime Commercial Space in Seguin
    $2,500/Mo
    1,200 SF

    Prime Commercial Space in Seguin

    Updated 1,200 SF commercial space in downtown Seguin.

    211 E Court Street, Seguin, TX 78155
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    Commercial Space Near Downtown Seguin
    $2,000/Mo
    3,000 SF

    Commercial Space Near Downtown Seguin

    Commercial space for lease near downtown Seguin, Texas.

    637 W Court Street, Seguin, TX 78155
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    Renovated Commercial Space Available
    $1,595/Mo
    1,565 SF

    Renovated Commercial Space Available

    Renovated commercial space with original hardwood floors, available April 2026.

    1427 N Austin Street, Seguin, TX 78155
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    Seguin Commercial Shop on Acreage
    $3,200/Mo
    1,856 SF

    Seguin Commercial Shop on Acreage

    Spacious shop on 5 acres, ideal for various business uses.

    1758 Ilka Switch, Seguin, TX 78155
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    Office Space Near Downtown Seguin
    $800/Mo
    4,554 SF

    Office Space Near Downtown Seguin

    Office space available in Seguin, Texas, near downtown.

    314 N Austin Street, Seguin, TX 78155
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    Highway Frontage Commercial Space
    $1,250/Mo
    6,750 SF

    Highway Frontage Commercial Space

    Commercial space for lease with high traffic and visibility.

    2331 N State Highway 46, Seguin, TX 78155
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    Move-in Ready Commercial Space
    $1,500/Mo
    5,400 SF

    Move-in Ready Commercial Space

    Commercial space near Guadalupe Regional Medical Center in Seguin, TX.

    412 N King Street, Seguin, TX 78155
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    Adaptable Commercial Building in Seguin
    $30 SF/Yr
    13,026 SF

    Adaptable Commercial Building in Seguin

    Well-maintained commercial building in high-traffic area, ideal for business.

    936 S Highway 123 Bypass, Seguin, TX 78155
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    Office and Warehouse Building Available
    $4,500/Mo
    16,555 SF

    Office and Warehouse Building Available

    16,555 sq ft office/warehouse on 2.61 acres.

    1012 Schriewer, Seguin, TX 78155
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    Renovated Commercial Space Available
    Contact for pricing
    1,565 SF

    Renovated Commercial Space Available

    Renovated retail/office/flex space with original hardwood floors.

    1427 N Austin St, Seguin, TX 78155
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    Warehouse with Office and Parking
    Contact for pricing
    3,200 SF

    Warehouse with Office and Parking

    3200 sqft warehouse with office, roll-up doors, ample parking.

    384 Partnership, Seguin, TX 78155
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    Seguin Office Space For Rent
    $3,800/Mo
    2,442 SF

    Seguin Office Space For Rent

    Office space available on IH 10 in Seguin, TX.

    3040 W Interstate 10 Expressway, Seguin, TX 78155
    View details
    Versatile Commercial Leasing Opportunity
    $0.95 SF/Yr
    9,000 SF

    Versatile Commercial Leasing Opportunity

    Premier commercial complex with flexible build-out options and ample yard space.

    7049 FM 1044, Marion, TX 78124
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    Office Space Near Downtown Seguin
    $800/Mo

    Office Space Near Downtown Seguin

    Office space available in building near downtown Seguin, Texas.

    314 N Austin St, Seguin, TX 78155
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    Seguin Office Space For Rent
    $6 SF/Yr
    5,000 SF

    Seguin Office Space For Rent

    Opportunity to build out space to tenant desires.

    1115 N Bowie Street, Seguin, TX 78155
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    Northeast Submarket Flex Space
    Contact for pricing
    7,252 SF

    Northeast Submarket Flex Space

    Class A construction with office space and dock high doors.

    6696 Tri County Parkway, Schertz, TX 78154
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    Office Space Available For Rent
    Contact for pricing

    Office Space Available For Rent

    Office space for rent at 515 N King St.

    515 N King St Ste 104, Seguin, TX 78155
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    Historic Downtown Seguin Commercial Building
    $4,888/Mo
    4,250 SF

    Historic Downtown Seguin Commercial Building

    Two-story commercial building in historic downtown Seguin available for rent.

    109 N River Street, Seguin, TX 78155
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    New Schertz Medical Office Building
    Contact for pricing
    9,010 SF

    New Schertz Medical Office Building

    New 9,010 SF medical office in Schertz, Texas.

    3795 Roy Richard Dr, Schertz, TX
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    Schertz Medical Center Office Space
    $32 SF/Yr
    1,250 SF

    Schertz Medical Center Office Space

    New medical development in a rapidly growing area.

    3701 FM3009, Schertz, TX
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    Office Space Available For Rent
    Contact for pricing
    12,572 SF

    Office Space Available For Rent

    Office space available for rent in Seguin, Texas.

    515 N King St Ste 104, Seguin, TX 78155
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    Industrial Warehouse with Office Space
    Contact for pricing
    11,950 SF

    Industrial Warehouse with Office Space

    11,950 SF warehouse with office, quick I-10 access.

    3391 FM465, Seguin, TX 78155
    View details

    Guadalupe County, TX Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Guadalupe County, TX with 32 listings featured on our commercial real estate exchange. The current inventory includes 78,352 square feet of properties with an estimated lease value of $206 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Guadalupe County, TX begin at $0.95 SF/Yr, with an average of $12 SF/Yr and extend to $32 SF/Yr.
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    Office properties & Spaces by market

    Browse Office properties & Spaces for Lease Near Guadalupe, TX

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