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South Carolina Retail Space for Lease

651 results
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Pawleys Island Class A Office
$2,250 / Mo
1,800 SF

Pawleys Island Class A Office

12019 Ocean Hwy, Pawleys Island, SC 29585

Class A office space in the heart of Pawleys Island.

  • Prime 1,800 sq ft Class A office space in Pawleys Island.
  • High‑visibility location with direct frontage on Highway 17 and a traffic light.
  • High traffic volume: VPD of more than 20,000.
  • Open layout with flexible space adaptable to various business needs.
  • Includes a small kitchenette and two private restrooms.
Updated: Feb 6
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Highway 17 Retail Space
$6,250 / Mo
4,500 SF

Highway 17 Retail Space

10589 N Kings Hwy, Myrtle Beach, SC 29572

Retail space with highway frontage in established Myrtle Beach building.

  • High visibility frontage on Highway 17.
  • Boasting 14 ft ceilings.
  • 4,500+\/- sq ft building.
  • Highway Commercial zoning.
  • Established building with long‑term retail tenant (shoe store).
Updated: Feb 5
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Murrells Inlet Office Space
$2,400 / Mo
1,250 SF

Murrells Inlet Office Space

Multi-tenant office/retail/medical building with easy highway access. Available 4/1/26.

637 Bellamy Ave, Murrells Inlet, SC 29576
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Murrells Inlet Office Space
$1,665 / Mo
1,250 SF

Murrells Inlet Office Space

Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

637 Bellamy Ave, Murrells Inlet, SC 29576
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Downtown Wagener Commercial Space Available
$1,695 / Mo
1,375 SF

Downtown Wagener Commercial Space Available

Premier commercial space in downtown Wagener, move-in ready and versatile.

108 Park St NW, Wagener, SC 29164
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Versatile Flex Space in Myrtle Beach
$4,750 / Mo
4,110 SF

Versatile Flex Space in Myrtle Beach

Adaptable commercial space for lease in the Arts & Innovation District.

716 8Th Ave N, Myrtle Beach, SC 29577
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Ribaut Road Commercial Space
$30 SF/Yr

Ribaut Road Commercial Space

Commercial space available for rent in Beaufort, South Carolina.

960 Ribaut Rd, Beaufort, SC 29902
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North Myrtle Beach Retail Space
$1,200 / Mo
1,000 SF

North Myrtle Beach Retail Space

Commercial retail space in North Myrtle Beach's Main Street.

401-B 1St Ave, North Myrtle Beach, SC 29582
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North Myrtle Beach Retail Space
$4,800 / Mo
3,000 SF

North Myrtle Beach Retail Space

Commercial retail or office space in North Myrtle Beach.

404-A Main St, North Myrtle Beach, SC 29582
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Renovated Retail/Office Space in Beaufort
$1,648 / Mo
3,485 SF

Renovated Retail/Office Space in Beaufort

Historic Beaufort commercial space with modern functionality and Southern charm.

609 Carteret St, Beaufort, SC 29902
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Prime Retail Space in Port Royal
$2,094 / Mo
436 SF

Prime Retail Space in Port Royal

Commercial unit in the heart of Port Royal, excellent visibility.

824 Paris Ave, Port Royal, SC 29935
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Aiken Retail or Office Space
$2,450 / Mo
1,632 SF

Aiken Retail or Office Space

Retail or office space in Aiken's CBD for lease.

126 Pendleton St SW, Aiken, SC 29801
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High-End Retail Space Available
$79,422
2,100 SF

High-End Retail Space Available

Newest shopping center in North Myrtle Beach, ready for upfitting.

900 S Highway 17 S, North Myrtle Beach, SC 29582
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Dillon, SC Commercial Building
$1,300 / Mo
1,485 SF

Dillon, SC Commercial Building

Standalone office/retail building for lease near Dillon's government hub.

307 W Harrison St, Dillon, SC 29536
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High-Traffic Commercial Space, Walterboro
$1,060 / Mo
21,780 SF

High-Traffic Commercial Space, Walterboro

Open space building in high-traffic Walterboro location, many potential uses.

1108 N Jefferies Blvd, Walterboro, SC 29488
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Downtown Beaufort Commercial Space Available
$3,700 / Mo

Downtown Beaufort Commercial Space Available

Versatile commercial space in the heart of Downtown Beaufort.

700 Bay St, Beaufort, SC 29902
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Retail Center Renovation in Little River
$1,913 / Mo
1,148 SF

Retail Center Renovation in Little River

Retail and office spaces available in renovated Little River center.

4390 Spa Dr, Little River, SC 29566
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Retail Space in Little River
$3,333 / Mo
2,000 SF

Retail Space in Little River

Retail space available in high-traffic Little River shopping center.

4390 Spa Dr, Little River, SC 29566
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Retail Space in Little River
$1,931 / Mo
1,159 SF

Retail Space in Little River

Retail space available in high-traffic Little River location.

4390 Spa Dr, Little River, SC 29566
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Commercial Space in Upscale Building
$2,800 / Mo
1,307 SF

Commercial Space in Upscale Building

Modern, high-end commercial space available for lease in Beaufort, SC.

8 Celadon Dr, Beaufort, SC 29907
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High Visibility Retail Space Available
$1,950 / Mo
1,250 SF

High Visibility Retail Space Available

Retail space in high-traffic area, ready for your business.

12270 Highway 17 Byp, Murrells Inlet, SC 29576
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Downtown Anderson Commercial Space Available
$1,350 / Mo
2,614 SF

Downtown Anderson Commercial Space Available

Versatile 1,300 SF space in historic downtown Anderson.

122 W Whitner St, Anderson, SC 29624
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Commercial Space on Sea Island Parkway
$2,750 / Mo
2,178 SF

Commercial Space on Sea Island Parkway

Commercial space with high visibility near Fripp and Hunting Islands.

2123 Sea Island Pkwy, Saint Helena Island, SC 29920
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Commercial Space on Harbor Island
$1,200 / Mo
436 SF

Commercial Space on Harbor Island

Commercial property with high visibility near Fripp and Hunting Islands.

2123 Sea Is Pkwy Unit, Saint Helena Island, SC 29920
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South Carolina Retail space Leasing Opportunities Market Analysis

Explore Retail space leasing options in South Carolina with 917 listings featured on our commercial real estate exchange. The current inventory includes 148,962,297,469 square feet of properties with an estimated lease value of $8,184 /Mo.

Estimated lease rates for Retail space in South Carolina begin at $0.58 SF/Yr, with an average of $23 SF/Yr and extend to $425 /Mo.
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