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Pickens County, SC Retail Properties & Spaces for Lease

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18 results
Downtown Clemson Retail Space Available
$2,800 /Mo

Downtown Clemson Retail Space Available

382 College Avenue, Clemson, SC 29631

Retail space in downtown Clemson, formerly a coffee shop.

  • Prime downtown Clemson location.
  • Approximately 2100 sqf. of finished space.
  • Accessible from Kieth St.
  • Central heating and cooling.
  • Durable brick construction.
Updated: Jun 12, 2025
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Easley Retail Leasing Opportunity
$10 SF/Yr
16,528 SF

Easley Retail Leasing Opportunity

1943 East Main Street, Easley, SC 29640

Turnkey retail space with high visibility and ample parking.

  • Turnkey retail space ready for immediate occupancy.
  • High‑visibility location at the gateway to Downtown Easley with ± 15,300 VPD.
  • Abundant on‑site parking available.
  • Open, spacious floor plan with high ceilings and ample lighting.
  • Multiple signage opportunities available.
Updated: Nov 26, 2025
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Easley Town Center Retail Space
Contact for pricing

Easley Town Center Retail Space

Retail space available in a 645,000 SF power center.

185 Rolling Hills Circle, Easley, SC 29640
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Retail Space on Highway 123
$15 SF/Yr
1,200 SF

Retail Space on Highway 123

Retail space in Easley's trade area with high visibility.

6811 Calhoun Memorial Hwy, Easley, SC
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Freestanding Restaurant Space Available
$40 SF/Yr
4,029 SF

Freestanding Restaurant Space Available

4,029 SF freestanding restaurant with drive-thru in Clemson, SC.

1071 Tiger Blvd, Clemson, SC
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Mixed-Use Property Near Clemson Campus
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Mixed-Use Property Near Clemson Campus

Mixed-use property with residential and retail components near Clemson University.

111 Earle Street, Clemson, SC 29631
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Remodeled Retail Building on Acreage
$34 SF/Yr
1,000 SF

Remodeled Retail Building on Acreage

Remodeled 1,000 SF retail building on 0.45 acres.

5536 Calhoun Memorial Hwy, Easley, SC
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Retail Space Near Clemson University
Contact for pricing
1,233 SF

Retail Space Near Clemson University

Publix-anchored retail space with high visibility near Clemson University.

1390 Tiger Blvd, Clemson, SC
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Downtown Easley Retail Space Available
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2,145 SF

Downtown Easley Retail Space Available

Retail suites available in Downtown Easley with courtyard access.

112 S Pendleton St, Easley, SC 29640
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Retail Space in High-Traffic Area
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1,396 SF

Retail Space in High-Traffic Area

Retail space with strong tenant mix and high visibility.

6101 Calhoun Memorial Hwy, Easley, SC
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Retail/Restaurant Space Near Clemson University
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1,401 SF

Retail/Restaurant Space Near Clemson University

Retail/restaurant spaces available in mixed-use student housing project.

114 Earle St, Clemson, SC
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Retail/Restaurant Space Near Clemson University
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3,500 SF

Retail/Restaurant Space Near Clemson University

Retail/restaurant space with dedicated parking and lake access.

894 Tiger Blvd, Clemson, SC
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Retail Space in West End
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1,800 SF

Retail Space in West End

Retail spaces available in high-traffic Easley location.

504 W Main St, Easley, SC 29640
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Retail Space Near Clemson University
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Retail Space Near Clemson University

Retail space on high-traffic corridor near Clemson University.

107 Canoy Ln, Clemson, SC 29631
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Retail Space in Pickens, SC
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16,188 SF

Retail Space in Pickens, SC

Retail spaces available within a shopping center.

2700 Gentry Memorial Hwy, Pickens, SC 29671
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Retail Space in Easley, SC
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Retail Space in Easley, SC

Retail space for rent with high traffic and ample parking.

5156 Calhoun Memorial Hwy, Easley, SC 29640
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Retail Space in Easley Village
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4,560 SF

Retail Space in Easley Village

Retail space available in a busy shopping center.

5155 Calhoun Memorial Hwy, Easley, SC 29640
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Retail Space on US Route
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950 SF

Retail Space on US Route

Retail suite available for lease with high visibility.

5115-5119 Calhoun Memorial Hwy, Easley, SC 29640
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Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 18 Active listings in Pickens County, SC, we suggest exploring alternatives. Similar 19 Properties for Sales.

Explore Similar Spaces for Sale in Pickens County, SC

Consider Similar Space for Sale. We found 19 Spaces matching your search parameters.

Easley Commercial Property on Highway
$249,900
0.49 Acres

Easley Commercial Property on Highway

High-visibility commercial lot near downtown Easley with office building.

609 E Main Street, Easley, SC 29640
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Easley Commercial Land Opportunity
$275,000
2.00 Acres

Easley Commercial Land Opportunity

2-acre commercial land with existing building, development potential.

2625 Farrs Bridge Road, Easley, SC 29640
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Downtown Easley Retail Opportunity
Contact for pricing

Downtown Easley Retail Opportunity

2,000 SF retail space in downtown Easley, SC.

106 N Pendleton Street, Easley, SC 29640
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Commercial Building on Highway 123
$1,349,990
0.48 Acres

Commercial Building on Highway 123

Commercial building in Clemson with ample parking and high traffic.

990 Tiger Boulevard, Clemson, SC 29631
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Dollar General Investment Opportunity
$846,720
9,100 SF

Dollar General Investment Opportunity

NNN leased Dollar General with strong operating history.

3711 Farrs Brg Rd, Easley, SC
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Highway 11 Retail Opportunity
$2,500,000
8,000 SF

Highway 11 Retail Opportunity

Retail property near Table Rock State Park on 7.23 acres.

107 Country Creek Dr, Pickens, SC 29671
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Pickens County, SC Retail properties & Spaces Leasing Opportunities Market Analysis

Explore Retail properties & Spaces leasing options in Pickens County, SC with 18 listings featured on our commercial real estate exchange. The current inventory includes 1,084,687,560 square feet of properties with an estimated lease value of $10 SF/Yr.

Estimated lease rates for Retail properties & Spaces in Pickens County, SC begin at $10 SF/Yr, with an average of $10 SF/Yr and extend to $10 SF/Yr.
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