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    Pickens County, SC Retail Properties & Spaces for Lease

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    26 properties
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    Downtown Retail Space
    Updated: Jun 12, 2025
    Downtown Retail Space

    382 College Avenue, Clemson, SC 29631

    $2,800/Mo
    Approximately 2,100 square feet of finished space
    Downtown Clemson location
    Access from Kieth St
    Positioned below The Fizz Boutique
    Formerly occupied by The Grace Coffee Shop
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    Corner End-Cap Retail Space
    Updated: Aug 1
    Corner End-Cap Retail Space

    1276 Eighteen Mile Rd, Central, SC 29630

    $18 SF/Yr
    2,856 sqft
    2,856 SF end‑cap retail suite
    Walmart shadow‑anchored shopping center
    Corner position with signage opportunities
    Direct access from main ingress and egress points
    Surrounded by national, regional, and local tenants
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    Renovated Retail Suite
    Renovated Retail Suite

    309 East Main Street, Pickens, SC 29671

    $1,100/Mo
    700 sqft

    Open layout with a private bath, tall ceilings, and abundant natural light.

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    Finished Coffee Shop Space
    Finished Coffee Shop Space

    382 College Avenue Basement Space, Clemson, SC 29631

    $2,800/Mo
    2,100 sqft

    Lower-level commercial space beneath The Fizz Boutique with Kieth St. access.

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    Ground-Floor Mixed-Use Suites
    Ground-Floor Mixed-Use Suites

    125 Anderson Hwy, Clemson, SC 29631

    Contact for pricing
    3,391 sqft

    Three leasing options within a student housing community accommodate retail, office, restaurant, and service-oriented uses.

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    First-Floor Retail and Office Suites
    First-Floor Retail and Office Suites

    125 Anderson Highway, Clemson, SC 29631

    $25 SF/Yr

    Three first-floor suites are available inside a 150-room, 500-bed student housing community on a high-traffic Clemson corridor.

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    Retail Office Suite with Frontage
    Retail Office Suite with Frontage

    838 Powdersville Road, Easley, SC 29642

    $14 SF/Yr

    Convenient retail/office suite in Carolina Center with 1,675 feet of road frontage on Powdersville Road.

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    Retail/Office Space For Rent
    Retail/Office Space For Rent

    5208-A Calhoun Memorial Hwy, Easley, SC 29640

    Contact for pricing
    1,200 sqft

    Retail/office space with high visibility and ample parking.

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    Retail or Office Suite
    Retail or Office Suite

    5823 Calhoun Memorial Highway, Easley, SC 29640

    Contact for pricing
    1,211 sqft

    Suite 1A provides flexible retail or office space within a highly visible shopping center with ample parking.

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    Retail Shopping Center with Parking
    Retail Shopping Center with Parking

    500 Old Greenville Hwy, Clemson, SC 29631

    Contact for pricing
    1,760 sqft 9.49 AC lot

    Retail suites ranging up to 13,802 SF are available within a shopping center in Clemson’s CP2 district.

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    Retail Space on Highway 123
    Retail Space on Highway 123

    6811 Calhoun Memorial Hwy, Easley, SC

    Contact for pricing
    1,200 sqft 0.90 AC lot

    Retail space in Easley's trade area with high visibility.

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    Retail Shopping Center Space
    Retail Shopping Center Space

    500 Old Greenville Hwy, Clemson, SC 29631

    Contact for pricing
    893 sqft 9.49 AC lot

    Retail space is available in a shopping center with free onsite parking in Clemson’s CP2 zoning.

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    Easley Town Center Retail Space
    Easley Town Center Retail Space

    185 Rolling Hills Circle, Easley, SC 29640

    Contact for pricing

    Retail space available in a 645,000 SF power center.

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    Downtown Easley Retail Space Available
    Downtown Easley Retail Space Available

    112 S Pendleton St, Easley, SC 29640

    Contact for pricing
    2,145 sqft

    Retail suites available in Downtown Easley with courtyard access.

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    Retail Space in High-Traffic Area
    Retail Space in High-Traffic Area

    6101 Calhoun Memorial Hwy, Easley, SC

    Contact for pricing
    1,396 sqft 20.21 AC lot

    Retail space with strong tenant mix and high visibility.

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    Versatile Garage/Storage Building for Rent
    Versatile Garage/Storage Building for Rent

    698 Mount Bethel Road, Sunset, SC 29685

    Contact for pricing

    Secure storage and workshop space with easy highway access.

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    Shopping Center Lease Space
    Shopping Center Lease Space

    500 Old Greenville Hwy, Clemson, SC 29631

    Contact for pricing
    4,680 sqft

    Lease space is available near Clemson University for retail shopping center use.

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    Ground-Floor Retail Restaurant Space
    Ground-Floor Retail Restaurant Space

    114 Earle St, Clemson, SC 29631

    Contact for pricing
    1,401 sqft

    Ground-floor commercial space with ample retail parking near Clemson University and College Avenue.

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    Mixed-Use Property Near Clemson Campus
    Mixed-Use Property Near Clemson Campus

    111 Earle Street, Clemson, SC 29631

    Contact for pricing

    Mixed-use property with residential and retail components near Clemson University.

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    Retail/Restaurant Space Near Clemson University
    Retail/Restaurant Space Near Clemson University

    114 Earle St, Clemson, SC

    Contact for pricing
    1,401 sqft 3.28 AC lot

    Retail/restaurant spaces available in mixed-use student housing project.

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    Retail Suite with Open Layout
    Retail Suite with Open Layout

    1067 Tiger Blvd, Clemson, SC 29631

    Contact for pricing
    1,300 sqft

    1,300 SF retail suite offers a wide-open sales area, rear storage, and two single-stall restrooms.

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    Retail Space in Pickens, SC
    Retail Space in Pickens, SC

    2700 Gentry Memorial Hwy, Pickens, SC 29671

    Contact for pricing
    16,188 sqft

    Retail spaces available within a shopping center.

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    Retail Space Near Clemson University
    Retail Space Near Clemson University

    107 Canoy Ln, Clemson, SC 29631

    Contact for pricing

    Retail space on high-traffic corridor near Clemson University.

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    Retail Space in Easley, SC
    Retail Space in Easley, SC

    5156 Calhoun Memorial Hwy, Easley, SC 29640

    Contact for pricing
    1.40 AC lot

    Retail space for rent with high traffic and ample parking.

    View details

    Pickens County, SC Retail properties & Spaces Market Trends and Statistics

    Explore Retail properties & Spaces leasing options in Pickens County, SC with 26 listings featured on our commercial real estate exchange. The current inventory includes 49,332 square feet of properties with an estimated lease value of $91.86.

    Estimated lease rates for Retail properties & Spaces in Pickens County, SC begin at $14 SF/Yr, with an average of $18.37 SF/Yr and extend to $25 SF/Yr.
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