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    Florence, SC Retail Properties & Spaces for Lease

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    Darlington, SC Timmonsville, SC Hartsville, SC
    13 results
    Versatile Commercial Space in Florence
    $5,000/Mo
    11,390 SF

    Versatile Commercial Space in Florence

    374 Darlington St., Florence, SC 29501

    Commercial property with bay doors, ideal for automotive or warehouse.

    • Prime Downtown Florence, SC location
    • Multiple bay doors for easy access and operations
    • Versatile space suitable for automotive, warehouse, or service‑related businesses
    • Abundant open space for vehicles, equipment, or flexible use
    • Dedicated office space for administrative functions
    Updated: Oct 11, 2025
    View details
    Retail Spaces in CrossRoads Center
    $18,134/Mo
    95,840 SF

    Retail Spaces in CrossRoads Center

    2522, 2524, 2528 David H McLeod Blvd, Florence, SC 29501

    Retail spaces available in high-traffic Florence commercial corridor.

    • High‑traffic location in Florence's main commercial corridor.
    • Convenient access to Interstate 20 and Interstate 95.
    • Located adjacent to Magnolia Mall.
    • Available spaces of ±18,134, ±34,430, and ±43,276 square feet.
    • Strong visibility to attract local residents and visitors.
    Updated: Apr 2
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    Retail Space in Regional Destination
    $22 SF/Yr
    2,800 SF

    Retail Space in Regional Destination

    Retail space available in premier shopping center, built in 2015.

    112-120 Woody Jones Blvd, Florence, SC
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    Warehouse with Showroom and Yard
    Contact for pricing

    Warehouse with Showroom and Yard

    Single tenant building with showroom, warehouse, and fenced yard.

    511 Irby Street, Florence, SC 29501
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    Retail Space in Regional Destination
    $25 SF/Yr
    2,400 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination, built in 2015.

    104 Woody Jones Blvd, Florence, SC
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    Florence Warehouse in West End
    $90 SF/Yr
    36,360 SF

    Florence Warehouse in West End

    Warehouse in Florence's West End District, near major retailers.

    2295 Hoffmeyer Rd, Florence, SC 29501
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    Retail Space in Florence, SC
    Contact for pricing
    8,000 SF

    Retail Space in Florence, SC

    8,000 SF retail space available for lease.

    2600 David H Mcleod Blvd, Florence, SC
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    Retail Space in Regional Destination
    $22 SF/Yr
    4,475 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination near major highways.

    110 Woody Jones Blvd, Florence, SC
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    Retail Space in Five Points
    $25 SF/Yr
    2,700 SF

    Retail Space in Five Points

    End-cap retail space in a high-traffic area for lease.

    1939 Hoffmeyer Rd, Florence, SC 29501
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    Established Commercial Complex on Second Loop
    Contact for pricing
    2,000 SF

    Established Commercial Complex on Second Loop

    Multi-tenant commercial complex with high visibility and convenient access.

    1800 2nd Loop Rd, Florence, SC 29501
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    Prime Outparcel Opportunities in Florence
    $1.00 SF/Yr

    Prime Outparcel Opportunities in Florence

    Outparcels available at I-95 interchange, ideal for hotels, restaurants.

    2939 N Williston Rd, Florence, SC 29506
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    Florence Commercial Space For Rent
    Contact for pricing

    Florence Commercial Space For Rent

    Commercial space suitable for office, professional, or retail use.

    2843 W Palmetto Street Suite C, Florence, SC 29501
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    Retail Space in Florence Mall
    Contact for pricing
    329,000 SF

    Retail Space in Florence Mall

    Prime retail space in regional shopping center, Florence, South Carolina.

    1945 W Palmetto St, Florence, SC 29501
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    Based on your search, we've compiled 52 Potential Opportunities for your consideration. Besides 13 Active listings in Florence, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 31 Properties for Sales.

    Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space Near Walmart
    $26 SF/Yr
    1,200 SF

    Retail Space Near Walmart

    Retail space available February 2026 near Walmart Supercenter.

    1211 Retail Row, Hartsville, SC 29550
    View details
    Retail Space For Lease
    $4 SF/Yr
    28,000 SF

    Retail Space For Lease

    28,000 SF retail space on 4.48 AC available.

    1404 N Main St, Marion, SC
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    Retail Space in Marion Center
    Contact for pricing
    1,300 SF

    Retail Space in Marion Center

    Retail and restaurant opportunities available in Marion Towne Center.

    2523-2565 US 76, Marion, SC
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    Retail Space in Hartsville, SC
    $6 SF/Yr
    14,204 SF

    Retail Space in Hartsville, SC

    Retail space available for lease in Hartsville, South Carolina.

    844 S 5th St, Hartsville, SC
    View details

    Similar Spaces for Sale in Florence, SC

    Consider Similar Space for Sale. We found 31 Spaces matching your search parameters.

    Remodeled Commercial Building Near Downtown
    $320,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    Turnkey commercial property in prime location with excellent visibility.

    910 W Evans st, Florence, SC 29501
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    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF

    Historic Downtown Florence Commercial Building

    16,000 SF historic building in thriving downtown Florence.

    248-260 W Evans st., Florence, SC 29501
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    Prime Commercial Property on Palmetto
    $250,000
    1,405 SF

    Prime Commercial Property on Palmetto

    High-visibility commercial property on a high-traffic street in Florence.

    2228 W Palmetto St., Florence, SC 29501
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    Fully Occupied Retail Center
    $1,650,000
    15,450 SF

    Fully Occupied Retail Center

    Retail center in good condition with high traffic count.

    823-817 S Cashua Drive, Florence, SC 29501
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    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Florence Commercial Development Opportunity
    $1,200,000
    4.54 Acres

    Florence Commercial Development Opportunity

    4.54 acre commercial parcel on high-traffic corridor.

    2621 West Palmetto Street, Florence, SC 29501
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    Versatile Commercial Parcel Near Downtown
    $499,900
    67,518 SF

    Versatile Commercial Parcel Near Downtown

    Office, showroom, and warehouse space less than one mile from Downtown.

    121 N Lawson St, Florence, SC 29501
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    Showroom and Warehouse on Irby
    $500,000
    6,120 SF

    Showroom and Warehouse on Irby

    Single tenant building with showroom and warehouse on 1.09-acre lot.

    511 Irby Street, Florence, SC 29501
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    NNN Leased Plasma Investment Property
    $3,370,000
    17,174 SF

    NNN Leased Plasma Investment Property

    NNN leased investment property in Florence, South Carolina.

    1933 2nd Loop Rd, Florence, SC 29501
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    Standalone Industrial Building on Harrell
    $189,000
    40,000 SF

    Standalone Industrial Building on Harrell

    Industrial building suitable for fabrication, automotive, contractor, or storage.

    120 N Guerry St, Florence, SC 29501
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    Office/Retail Conversion Opportunity
    $400,000
    2,600 SF

    Office/Retail Conversion Opportunity

    2600 SF residence on 1.6 acres, suitable for conversion.

    2901 W Palmetto Street, Florence, SC 29501
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Development Ready Outparcel in Myrtle Beach
    $95,000 SF/Yr

    Development Ready Outparcel in Myrtle Beach

    1.17 acre commercial land with high traffic counts.

    1028 Glenforest Rd., Myrtle Beach, SC 29579
    View details
    Commercial Land in Murrells Inlet
    $2,500/Mo

    Commercial Land in Murrells Inlet

    1.49 acres of commercial land for lease.

    Inlet Square Dr., Murrells Inlet, SC 29576
    View details
    Marshville Commercial Land For Rent
    $6,000/Mo

    Marshville Commercial Land For Rent

    Commercial land available for rent in Marshville, North Carolina.

    601 N Carelock Drive, Marshville, NC 28103
    View details
    Commercial Land in Southern Pines
    $3,500/Mo

    Commercial Land in Southern Pines

    1.297-acre commercial land site for lease in a high-traffic area.

    Pinehurst Avenue, Southern Pines, NC 28387
    View details

    Florence, SC Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Florence, SC with 13 listings featured on our commercial real estate exchange. The current inventory includes 155,965 square feet of properties with an estimated lease value of $191 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Florence, SC begin at $2 SF/Yr, with an average of $27 SF/Yr and extend to $90 SF/Yr.
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