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    Orangeburg County, SC Retail Properties & Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    11 listings
    Retail Space with Drive-Thru
    Contact for pricing
    10,725 SF
    Retail Space with Drive-Thru

    1535 John C Calhoun, Orangeburg, SC

    Former CVS space with drive-thru, outparcel to WalMart.
    • Outparcel to a WalMart Neighborhood Market
    • Former CVS with drive thru, offering ~10,725 SF
    • Located on the hard corner of John C. Calhoun Drive at Stonewall Jackson Street
    • Prominent Pylon Sign with Digital Reader Board
    • Access on John C. Calhoun and Stonewall Jackson
    Updated: Nov 5, 2025
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    High-Traffic Corner Retail Space
    Contact for pricing
    1,800 SF
    High-Traffic Corner Retail Space

    8507 Old State Road, Holly Hill, SC 29059

    1,800 sq ft retail space in high-traffic Holly Hill.
    • High‑traffic corner location at Pine Street and Hwy 176/Old State Road.
    • Exceptional road frontage and visibility.
    • Located across from Piggly Wiggly and V‑Go Gas Station, adjacent to CVS Pharmacy.
    • 1,800 square feet of retail space.
    • Recently updated (within the past 4 years).
    Updated: Mar 3
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    Retail Space Near Walmart
    Contact for pricing
    1,500 SF
    Retail Space Near Walmart

    Retail space available in shadow-anchored shopping center.

    2805-2831 North Rd, Orangeburg, SC

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    Retail, Office
    Contact for pricing
    1,250 SF
    Retail, Office

    Retail space · 1,250 SF

    8515 Old State Road, Holly Hill, SC 29059

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    Retail Space in Orangeburg, SC
    Contact for pricing
    4,625 SF
    Retail Space in Orangeburg, SC

    Retail space available for lease in Orangeburg, South Carolina.

    437 Stonewall Jackson Street Southwest, Orangeburg, SC

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    Retail Space in Orangeburg
    Contact for pricing
    524 SF
    Retail Space in Orangeburg

    Retail space available for lease in Orangeburg, SC.

    1350 Grove Park Dr, Orangeburg, SC

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    Orangeburg Commercial Property for Lease
    Contact for pricing
    Orangeburg Commercial Property for Lease

    Commercial property available for lease in Orangeburg, South Carolina.

    Magnolia Village Parkway @ North Rd (US 178), Orangeburg, SC 29118

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    Retail Space on Hwy 178
    Contact for pricing
    11,700 SF
    Retail Space on Hwy 178

    Retail opportunities in high-growth corridor near major retailers.

    2580 North Rd, Orangeburg, SC

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    Restaurant Space Available For Rent
    $10 SF/Yr
    6,000 SF
    Restaurant Space Available For Rent

    Restaurant and retail spaces available for rent.

    1214 St Matthews Rd NE, Orangeburg, SC 29118

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    Retail Space in Grove Park
    Contact for pricing
    Retail Space in Grove Park

    Retail spaces available in a busy Orangeburg shopping center.

    1370 Chestnut St, Orangeburg, SC 29115

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    Downtown Holly Hill Commercial Space
    $12 SF/Yr
    Downtown Holly Hill Commercial Space

    Commercial space for lease in renovated historic building.

    8636 Old State Rd, Holly Hill, SC 29059

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    Based on your search, we've compiled 40 Potential Opportunities for your consideration. Besides 11 Active listings in Orangeburg County, SC, we suggest exploring alternatives. Similar 25 Properties for Sales.

    Similar Spaces for Sale in Orangeburg County, SC

    Consider Similar Space for Sale. We found 25 Spaces matching your search parameters.

    Elloree Commercial Portfolio For Sale
    $1,475,000
    13,900 SF
    Elloree Commercial Portfolio For Sale

    Five buildings in Elloree, SC, suitable for retail, office, mixed-use.

    2725 Cleveland Street, Elloree, SC 29047

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    Turnkey Restaurant Opportunity in Norway
    $299,000
    2,800 SF
    Turnkey Restaurant Opportunity in Norway

    Fully equipped restaurant for sale, ready for immediate operation.

    8291 Savannah Highway, Norway, SC 29113

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    Orangeburg Commercial Property with Warehouse
    $249,900
    6,000 SF
    Orangeburg Commercial Property with Warehouse

    Two buildings ideal for office, retail, or warehouse use.

    2874 Bamberg Road, Orangeburg, SC 29115

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    Highway Commercial Property with Storage
    $1,900,000
    3,282 SF
    Highway Commercial Property with Storage

    Commercial building with storage units near I-95 in Santee.

    9158 Old Number Six Highway, Santee, SC 29142

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    Historic Mixed-Use Building in Elloree
    $275,000
    5,928 SF
    Historic Mixed-Use Building in Elloree

    Prime investment opportunity in growing Elloree near Lake Marion.

    2720 W Cleveland Street, Elloree, SC 29047

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    Freestanding Family Dollar Store
    $900,000
    8,000 SF
    Freestanding Family Dollar Store

    Single tenant Family Dollar store in Eutawville, SC for sale.

    12155 Old Number Six Hwy, Eutawville, SC 29048

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    Neighborhood Commercial Warehouse Property
    $69,900
    0.68 Acres
    Neighborhood Commercial Warehouse Property

    Two-building industrial setup with parking, zoned neighborhood commercial for owner-use or rental income.

    2918 Cleveland Street, Elloree, SC 29047

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    Freestanding Retail Property For Sale
    $1,394,000
    9,993 SF
    Freestanding Retail Property For Sale

    Freestanding retail property with investment-grade tenant Dollar Tree.

    100 Bass Dr, Santee, SC

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    Eutawville Commercial Lot For Sale
    $49,900
    0.34 Acres
    Eutawville Commercial Lot For Sale

    0.34-acre commercial lot ideal for office, retail, or restaurant development.

    Old Number Six Highway, Eutawville, SC 29048

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    Leased Retail Center For Sale
    $699,500
    5,000 SF
    Leased Retail Center For Sale

    5,000 SF fully leased retail center in Orangeburg, SC.

    1260 Ridgewood Dr, Orangeburg, SC 29118

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    Historic Commercial Gem in North
    $50,000
    2,300 SF
    Historic Commercial Gem in North

    Charming commercial property with endless possibilities in a central location.

    508 Main Street, North, SC 29112

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    Retail Site in Orangeburg, SC
    Contact for pricing
    4,869 SF
    Retail Site in Orangeburg, SC

    1.32-acre retail site with 4,869 SF available.

    Orangeburg, SC 29118

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    Commercial Land in Orangeburg, SC
    $900,000
    9.02 Acres
    Commercial Land in Orangeburg, SC

    9-acre commercial property with high visibility and versatile zoning.

    1951 Old Edisto Drive, Orangeburg, SC 29115

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Aiken Commercial Land For Lease
    $4,200/Mo
    Aiken Commercial Land For Lease

    2.449 acre commercial land for lease in Aiken, SC.

    E Pine Log, Aiken, SC 29803

    View details
    Retail Land Lease Opportunity
    $95,000 SF/Yr
    46,114 SF
    Retail Land Lease Opportunity

    Retail land for lease in Mount Pleasant's shopping district.

    1734 N Highway 17, Mount Pleasant, SC 29464

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    High-Traffic Commercial Land For Rent
    $5,000/Mo
    High-Traffic Commercial Land For Rent

    Commercial land in high-traffic Beaufort location, suitable for various uses.

    91 Sea Island Parkway, Beaufort, SC 29907

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    Commercial Land in Murrells Inlet
    $2,500/Mo
    Commercial Land in Murrells Inlet

    1.49 acres of commercial land for lease.

    Inlet Square Dr., Murrells Inlet, SC 29576

    View details

    Orangeburg County, SC Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Orangeburg County, SC with 11 listings featured on our commercial real estate exchange. The current inventory includes 6,000 square feet of properties with an estimated lease value of $10 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Orangeburg County, SC begin at $10 SF/Yr, with an average of $10 SF/Yr and extend to $10 SF/Yr.
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