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    Lake City, SC
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    Lake City, SC Retail Properties & Spaces for Sale

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    Scranton, SC Coward, SC Cades, SC Kingstree, SC Timmonsville, SC Olanta, SC Salters, SC Pamplico, SC
    Freestanding Storefront Building
    Updated: Aug 26
    Freestanding Storefront Building

    205 W Main St, Lake City, SC 29560

    $700,000
    5,410 sqft
    ±5,410 SF freestanding storefront building
    Retail, office, and professional service use potential
    Suitable for an owner‑occupant or tenant
    205 W Main Street location in downtown Lake City
    Near local businesses, banks, restaurants, and public services
    View details
    Storefront Building with Rear Parking
    Updated: Jun 2
    Storefront Building with Rear Parking

    105 W Main St, Lake City, SC 29560

    $247,000
    2,425 sqft 0.50 AC lot
    Flexible space for retail, office, event, hospitality, or mixed‑use development
    2 bathrooms and distinctive tin ceilings
    Building located on .50+/- acres with an approximately half‑acre rear lot for parking, storage, expansion, or development
    Metal roof installed in 2011; rewired in 2016; facade and windows updated in 2025
    Downtown Lake City Main Street visibility with strong pedestrian and vehicle traffic
    View details
    NNN Wireless Retail Property
    NNN Wireless Retail Property

    218 N Ron McNair Blvd, Lake City, SC 29560

    Contact for pricing
    1,956 sqft

    Single-tenant wireless facility with corporate occupancy, recent renovations, and commercial zoning along a high-traffic boulevard.

    View details
    See what stands out in Florence County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Prime Commercial Site on Highway
    Prime Commercial Site on Highway

    791 South Ron McNair Boulevard, Lake City, SC 29560

    $599,000
    2.90 AC lot

    Development opportunity in high-traffic commercial corridor near industrial area.

    View details
    Two-Story Mixed-Use Building
    Two-Story Mixed-Use Building

    113 & 115 W Main St, Lake City, SC 29560

    Contact for pricing

    Two storefronts offer separate entrances, bathrooms, and central HVAC, with an unfinished second level for future configuration.

    View details
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 5 Active listings in Lake City, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 67 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Three-Bay Auto Shop
    Three-Bay Auto Shop

    321 N Williamsburg County Hwy., Kingstree, SC 29556

    $168,000
    3,150 sqft

    Highway-accessible shop with office, restrooms, and fenced rear storage area.

    View details
    Three-Bay Auto Shop
    Three-Bay Auto Shop

    321 N Williamsburg County Hwy., Kingstree, SC 29556

    $168,000
    3,150 sqft 0.50 AC lot

    Commercial shop with highway access, office space, two bathrooms, and a secured rear area with storage containers.

    View details
    Gas Station with Deli
    Gas Station with Deli

    1312 Vox Hwy, Johnsonville, SC 29555

    Contact for pricing
    2,380 sqft

    Commercially zoned gas station with a deli operation, on-site parking, and an established local customer base.

    View details
    Family Dollar NNN Retail Property
    Family Dollar NNN Retail Property

    141 W Myrtle Beach Hwy, Johnsonville, SC 29555

    Contact for pricing
    10,500 sqft

    The lease runs through July 31, 2033, with five five-year renewal options.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Corner Commercial Land
    Corner Commercial Land

    360 S Ron McNair Blvd, Lake City, SC 29560

    $59,900
    1,200 sqft 0.12 AC lot

    Corner commercial parcel with brick construction, concrete flooring, and central air.

    View details
    Cleared Commercial Land
    Cleared Commercial Land

    2 Acres-TBD N Williamsburg County Hwy., Kingstree, SC 29556

    $275,000
    2.00 AC lot

    Two-acre commercial parcel with public water and a cleared site ready for future development.

    View details
    Commercial Land Parcel
    Commercial Land Parcel

    211 E Main St., Kingstree, SC 29556

    $50,000
    0.08 AC lot

    Core Comm-zoned land across from Kingstree’s Amtrak station on East Main Street.

    View details
    C1 Commercial Land with Parking
    C1 Commercial Land with Parking

    312 E Broad St., Hemingway, SC 29554

    $185,000
    1.80 AC lot

    C1-zoned commercial parcel with existing blacktop parking and a pylon sign.

    View details

    Off-Market Properties in Lake City, SC

    Consider similar Off-Market properties in Lake City, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    121 Mcallister St
    WHOLESALE OUTLET, DISCOUNT STORE

    121 Mcallister St, Lake City, SC 29560

    $130,000
    Estimated value
    480 sqft 0.49 AC lot
    View details
    324 Main St
    AUTO REPAIR, GARAGE

    324 Main St, Lake City, SC 29560-2316

    $320,000
    Estimated value
    5,440 sqft 1.18 AC lot
    View details
    2218 Lk City Hwy
    WHOLESALE OUTLET, DISCOUNT STORE

    2218 Lk City Hwy, Lake City, SC 29560

    $55,000
    Estimated value
    2,112 sqft 1.12 AC lot
    View details
    130 Acline St
    WHOLESALE OUTLET, DISCOUNT STORE

    130 Acline St, Lake City, SC 29560-2130

    $265,000
    Estimated value
    11,656 sqft 0.31 AC lot
    View details
    104 Main St
    WHOLESALE OUTLET, DISCOUNT STORE

    104 Main St, Lake City, SC 29560-2627

    $110,000
    Estimated value
    2,000 sqft 0.07 AC lot
    View details
    266 Main St
    FINANCIAL BUILDING

    266 Main St, Lake City, SC 29560-2444

    $145,000
    Estimated value
    2,660 sqft 0.41 AC lot
    View details
    State Hwy 341
    WHOLESALE OUTLET, DISCOUNT STORE

    State Hwy 341, Lake City, SC 29560

    $95,000
    Estimated value
    3,909 sqft 6.30 AC lot
    View details
    148 Main St
    WHOLESALE OUTLET, DISCOUNT STORE

    148 Main St, Lake City, SC 29560-2426

    $50,000
    Estimated value
    1,752 sqft 0.05 AC lot
    View details
    150 Main St, Unit 3
    WHOLESALE OUTLET, DISCOUNT STORE

    150 Main St, Lake City, SC 29560-2426

    Unit 3
    $75,000
    Estimated value
    2,625 sqft 0.05 AC lot
    View details
    120 Ron Mcnair Blvd
    AUTO REPAIR, GARAGE

    120 Ron Mcnair Blvd, Lake City, SC 29560-3294

    $125,000
    Estimated value
    4,860 sqft 0.48 AC lot
    View details
    121 Main St
    WHOLESALE OUTLET, DISCOUNT STORE

    121 Main St, Lake City, SC 29560-2425

    $65,000
    Estimated value
    2,800 sqft 0.64 AC lot
    View details
    262 Williamsburg Ave
    WHOLESALE OUTLET, DISCOUNT STORE

    262 Williamsburg Ave, Lake City, SC 29560-2736

    Value Estimation by Request
    972 sqft 0.06 AC lot
    View details
    111 Acline St
    WHOLESALE OUTLET, DISCOUNT STORE

    111 Acline St, Lake City, SC 29560-2129

    $165,000
    Estimated value
    1,705 sqft 0.04 AC lot
    View details
    110 Sauls St
    BARBER, HAIR SALON

    110 Sauls St, Lake City, SC 29560-2631

    $60,000
    Estimated value
    1,650 sqft 0.04 AC lot
    View details
    842 Main St
    RESTAURANT

    842 Main St, Lake City, SC 29560-2232

    $160,000
    Estimated value
    4,950 sqft 1.62 AC lot
    View details
    152 Main St
    WHOLESALE OUTLET, DISCOUNT STORE

    152 Main St, Lake City, SC 29560-2426

    $200,000
    Estimated value
    1,825 sqft 0.05 AC lot
    View details
    203 Mccutcheon Rd
    WHOLESALE OUTLET, DISCOUNT STORE

    203 Mccutcheon Rd, Lake City, SC 29560-5646

    $100,000
    Estimated value
    1,632 sqft 0.73 AC lot
    View details
    427 Ron Mcnair Blvd
    WHOLESALE OUTLET, DISCOUNT STORE

    427 Ron Mcnair Blvd, Lake City, SC 29560-3425

    Value Estimation by Request
    448 sqft 0.14 AC lot
    View details
    224 Ron Mcnair Blvd
    WHOLESALE OUTLET, DISCOUNT STORE

    224 Ron Mcnair Blvd, Lake City, SC 29560-2508

    $65,000
    Estimated value
    2,511 sqft 0.45 AC lot
    View details

    Lake City, SC Retail Properties & Spaces Market Trends and Statistics

    Explore 72 retail properties & spaces for sale in Lake City, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 9,791 square feet of properties for sale, with an estimated market value of $1,546,000.

    Sale prices for stores in Lake City, SC start at $247,000, averaging $515,333, and reaching up to $700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Storefront properties 4
    Automotive properties 1
    Truck stops 1

    Demographics Overview

    Population 12K
    Population Growth (5Y) -7.6%
    Median Household Income $45,421
    College Educated 24.6%

    High-Yield Neighborhoods for Investment

    Identify Lake City submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29560 $515.3K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Florence County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Florence County

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