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Lake City, SC Retail Properties & Spaces for Sale

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Prime Commercial Lot on Highway
$599,000
2.90 Acres

Prime Commercial Lot on Highway

791 S Ron McNair Blvd., Lake City, SC 29560

2.9-acre commercial site on S. Ron McNair Boulevard, Lake City.

  • ±2.90‑acre commercial site on S. Ron McNair Boulevard / Highway 52 corridor.
  • High traffic count of approximately 15,000 vehicles per day.
  • Located adjacent to Nan Ya Plastics, a major regional employer.
  • Clean Phase I Environmental Site Assessment in hand.
  • Site will be cleared of existing structures for redevelopment.
Updated: Mar 9
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Downtown Lake City Commercial Building
$199,000
2,500 SF

Downtown Lake City Commercial Building

112 E Main St, Lake City, SC 29560

2,500 sq ft commercial building in downtown Lake City.

  • Prime Main Street location in downtown Lake City, SC
  • 2,500 sq ft commercial building suitable for various business concepts
  • Existing built‑in bar, ideal for restaurant,
Updated: Mar 24
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Prime Commercial Site on Highway
$599,000

Prime Commercial Site on Highway

Development opportunity in high-traffic commercial corridor near industrial area.

791 S Ron McNair Blvd, Lake City, SC 29560
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Commercial Lot in Lake City
$160,000
0.47 Acres

Commercial Lot in Lake City

0.47 acre commercial lot with rental income potential.

0.47 Acres-TBD Sumter St., Lake City, SC 29560
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Based on your search, we've compiled 243 Potential Opportunities for your consideration. Besides 4 Active listings in Lake City, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 231 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mechanic Shop on Highway 52
$178,000
3,150 SF

Mechanic Shop on Highway 52

Mechanic shop with three bays on heavily traveled Highway.

321 N Williamsburg County Hwy., Kingstree, SC 29556
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Olanta Commercial Building on US 301
$60,000
1,500 SF

Olanta Commercial Building on US 301

Commercial building in Olanta, SC, with multiple business possibilities.

405 N Jones Road, Olanta, SC 29114
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Olanta Commercial Building on US 301
$60,000
1,500 SF

Olanta Commercial Building on US 301

Commercial building in Olanta, SC, with multiple business possibilities.

405 N Jones Road, Olanta, SC 29114
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Restaurant Opportunity on Corner Lot
$199,900

Restaurant Opportunity on Corner Lot

Commercial property with restaurant equipment on 2.8-acre corner lot.

8451 Hemingway Highway, Kingstree, SC 29556
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Downtown Lake City Commercial Lot
$59,900
1,200 SF

Downtown Lake City Commercial Lot

Commercial lot in downtown Lake City, South Carolina.

360 S Ron McNair Blvd, Lake City, SC 29560
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Cleared Commercial Lot in Kingstree
$275,000
2.00 Acres

Cleared Commercial Lot in Kingstree

2-acre commercial lot on N Williamsburg County Highway, Kingstree, SC.

2 Acres-TBD N Williamsburg County Hwy., Kingstree, SC 29556
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Commercial Lot in Kingstree, SC
$50,000
0.08 Acres

Commercial Lot in Kingstree, SC

Commercial property in the heart of Kingstree, South Carolina.

211 E Main St., Kingstree, SC 29556
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Prime Land in Pamplico, SC
$99,000
2.00 Acres

Prime Land in Pamplico, SC

Two-acre commercial land with high visibility and road frontage.

S Pamplico Highway, Pamplico, SC 29583
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Explore Off-Market Properties in Lake City, SC

Consider similar Off-Market properties in Lake City, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

121 Mcallister St

121 Mcallister St

WHOLESALE OUTLET, DISCOUNT STORE • 480 SF
Value Estimation by Request
121 Mcallister St, Lake City, SC 29560
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324 Main St

324 Main St

AUTO REPAIR, GARAGE • 5,440 SF
Value Estimation by Request
324 Main St, Lake City, SC 29560-2316
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2218 Lk City Hwy

2218 Lk City Hwy

WHOLESALE OUTLET, DISCOUNT STORE • 2,112 SF
Value Estimation by Request
2218 Lk City Hwy, Lake City, SC 29560
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130 Acline St

130 Acline St

WHOLESALE OUTLET, DISCOUNT STORE • 11,656 SF
Value Estimation by Request
130 Acline St, Lake City, SC 29560-2130
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104 Main St

104 Main St

WHOLESALE OUTLET, DISCOUNT STORE • 2,000 SF
Value Estimation by Request
104 Main St, Lake City, SC 29560-2627
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266 Main St

266 Main St

FINANCIAL BUILDING • 2,660 SF
Value Estimation by Request
266 Main St, Lake City, SC 29560-2444
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State Hwy 341

State Hwy 341

WHOLESALE OUTLET, DISCOUNT STORE • 3,909 SF
Value Estimation by Request
State Hwy 341, Lake City, SC 29560
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148 Main St

148 Main St

WHOLESALE OUTLET, DISCOUNT STORE • 1,752 SF
Value Estimation by Request
148 Main St, Lake City, SC 29560-2426
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150 Main St, Unit 3

150 Main St, Unit 3

WHOLESALE OUTLET, DISCOUNT STORE • 2,625 SF
Value Estimation by Request
150 Main St, Lake City, SC 29560-2426
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120 Ron Mcnair Blvd

120 Ron Mcnair Blvd

AUTO REPAIR, GARAGE • 4,860 SF
Value Estimation by Request
120 Ron Mcnair Blvd, Lake City, SC 29560-3294
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121 Main St

121 Main St

WHOLESALE OUTLET, DISCOUNT STORE • 2,800 SF
Value Estimation by Request
121 Main St, Lake City, SC 29560-2425
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262 Williamsburg Ave

262 Williamsburg Ave

WHOLESALE OUTLET, DISCOUNT STORE • 972 SF
Value Estimation by Request
262 Williamsburg Ave, Lake City, SC 29560-2736
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111 Acline St

111 Acline St

WHOLESALE OUTLET, DISCOUNT STORE • 1,705 SF
Value Estimation by Request
111 Acline St, Lake City, SC 29560-2129
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110 Sauls St

110 Sauls St

BARBER, HAIR SALON • 1,650 SF
Value Estimation by Request
110 Sauls St, Lake City, SC 29560-2631
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842 Main St

842 Main St

RESTAURANT • 4,950 SF
Value Estimation by Request
842 Main St, Lake City, SC 29560-2232
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152 Main St

152 Main St

WHOLESALE OUTLET, DISCOUNT STORE • 1,825 SF
Value Estimation by Request
152 Main St, Lake City, SC 29560-2426
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203 Mccutcheon Rd

203 Mccutcheon Rd

WHOLESALE OUTLET, DISCOUNT STORE • 1,632 SF
Value Estimation by Request
203 Mccutcheon Rd, Lake City, SC 29560-5646
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427 Ron Mcnair Blvd

427 Ron Mcnair Blvd

WHOLESALE OUTLET, DISCOUNT STORE • 448 SF
Value Estimation by Request
427 Ron Mcnair Blvd, Lake City, SC 29560-3425
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224 Ron Mcnair Blvd

224 Ron Mcnair Blvd

WHOLESALE OUTLET, DISCOUNT STORE • 2,511 SF
Value Estimation by Request
224 Ron Mcnair Blvd, Lake City, SC 29560-2508
View details
3432 12th Mckenzie Rd

3432 12th Mckenzie Rd

AUTO REPAIR, GARAGE • 1,800 SF
Value Estimation by Request
3432 12th Mckenzie Rd, Lake City, SC 29560-5213
View details

Lake City, SC Retail Properties & Spaces Investment Opportunities Market Analysis

Explore 235 retail properties & spaces for sale in Lake City, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 3,332,159 square feet of properties for sale, with an estimated market value of $23,504,000.

Sale prices for stores in Lake City, SC start at $50,000, averaging $204,382, and reaching up to $1,475,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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