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    Florence, SC Retail Properties & Spaces for Sale

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    Columbia, SC Aiken, SC Beaufort, SC
    33 results
    Remodeled Commercial Building Near Downtown
    $340,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    910 W Evans st, Florence, SC 29501

    Turnkey commercial property in prime location with excellent visibility.

    • Completely remodeled/rebuilt from the ground up with new roof, HVAC, electrical, and plumbing.
    • Prime location minutes from downtown Florence with excellent visibility and access.
    • Turnkey property suitable for a medical office, salon, law firm, or small business.
    • Five spacious rooms that can serve as private offices or treatment spaces.
    • Modern kitchen with brand‑new cabinets and granite countertops.
    Updated: Apr 1
    View details
    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF

    Historic Downtown Florence Commercial Building

    248-260 W Evans st., Florence, SC 29501

    16,000 SF historic building in thriving downtown Florence.

    • Prime downtown Florence location in a thriving area.
    • Large 16,000 sq ft historic building with limitless potential.
    • Significant parking available (over 100 spaces), rare for downtown.
    • Versatile space currently configured with multiple tenants (Law Firm, H&R Block, Hair Studio).
    • Spacious 1.47‑acre lot allows for growth and development.
    Updated: Mar 9
    View details
    Industrial Building in Florence, SC
    $550,000
    67,518 SF

    Industrial Building in Florence, SC

    Standalone industrial building suitable for various commercial and industrial uses.

    121 Lawson St, Florence, SC 29501
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    Established Auto Body Business For Sale
    $1,305,000
    4,125 SF

    Established Auto Body Business For Sale

    Turn-key auto body business with equipment, client roster, and real estate.

    803 Ranch Rd., Florence, SC 29506
    View details
    Industrial Buildings with Power & Access
    $199,000
    40,000 SF

    Industrial Buildings with Power & Access

    Two industrial buildings ideal for fabrication, automotive, or storage.

    120 N Guerry Street, Florence, SC 29501
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    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Turnkey Fish Market Opportunity
    $250,900
    2,499 SF

    Turnkey Fish Market Opportunity

    Profitable, equipped fish market for sale in Florence, SC.

    1401 W Darlington Street, Florence, SC 29501
    View details
    Versatile Commercial Parcel Near Downtown
    $499,900
    67,518 SF

    Versatile Commercial Parcel Near Downtown

    Office, showroom, and warehouse space less than one mile from Downtown.

    121 N Lawson St, Florence, SC 29501
    View details
    Former Convenience Store Investment Property
    $125,000
    2,400 SF

    Former Convenience Store Investment Property

    Fixer-upper retail property with 150' frontage, great investment potential.

    1134 E Howe Springs Road, Florence, SC 29505
    View details
    Retail Property Near Major Intersections
    Contact for pricing
    38,000 SF

    Retail Property Near Major Intersections

    Retail property with high visibility and easy access.

    2640 W. Palmetto, Florence, SC 29501
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    Showroom and Warehouse on Irby
    $500,000
    6,120 SF

    Showroom and Warehouse on Irby

    Single tenant building with showroom and warehouse on 1.09-acre lot.

    511 Irby Street, Florence, SC 29501
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    NNN Leased Plasma Investment Property
    $3,370,000
    17,174 SF

    NNN Leased Plasma Investment Property

    NNN leased investment property in Florence, South Carolina.

    1933 2nd Loop Rd, Florence, SC 29501
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    Standalone Industrial Building on Harrell
    $189,000
    40,000 SF

    Standalone Industrial Building on Harrell

    Industrial building suitable for fabrication, automotive, contractor, or storage.

    120 N Guerry St, Florence, SC 29501
    View details
    Office/Retail Conversion Opportunity
    $400,000
    2,600 SF

    Office/Retail Conversion Opportunity

    2600 SF residence on 1.6 acres, suitable for conversion.

    2901 W Palmetto Street, Florence, SC 29501
    View details
    Evans Street Commercial Redevelopment Opportunity
    $79,000
    1,200 SF

    Evans Street Commercial Redevelopment Opportunity

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    8,000 SF Retail Opportunity
    $1,521,444
    8,000 SF

    8,000 SF Retail Opportunity

    Family Dollar retail property for sale in Florence, SC.

    3216 E Palmetto St, Florence, SC 29506
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    Walgreens
    $4,750,000
    14,500 SF

    Walgreens

    Opportunity to acquire an absolute NNN Leased Walgreens located in Florence, SC

    2498 2nd Loop Rd, Florence, SC 29501
    View details
    Historic Downtown Florence Building For Sale
    $2,800,000
    16,304 SF

    Historic Downtown Florence Building For Sale

    16,000 SF historic building in downtown Florence for sale.

    248,258, and 268 W. Evans St., Florence, SC 29501
    View details
    South Irby Street Commercial Lot
    $255,000

    South Irby Street Commercial Lot

    0.46 acre lot suitable for retail or office development.

    623 South Irby Street, Florence, SC 29501
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    Wendy's Restaurant For Sale
    Contact for pricing
    2,058 SF

    Wendy's Restaurant For Sale

    Wendy’s in Florence, South Carolina, leased for 20 years.

    4010 E Palmetto St, Florence, SC
    View details
    Wendy’s Restaurant in Florence, SC
    Contact for pricing
    2,202 SF

    Wendy’s Restaurant in Florence, SC

    Wendy’s restaurant for sale on high-traffic retail corridor.

    624 S Irby St, Florence, SC
    View details
    Versatile Office Building For Sale
    $262,500
    2,004 SF

    Versatile Office Building For Sale

    Functional office building in high traffic area, ideal for professionals.

    603 W Palmetto Street, Florence, SC 29501
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    Prime Commercial Land I-95 Exit
    Contact for pricing

    Prime Commercial Land I-95 Exit

    Strategically located commercial land near I-95, Florence, SC.

    W Palmetto St, Florence, SC 29501
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    Retail, Special Purpose
    $400,000
    3,375 SF

    Retail, Special Purpose

    Retail space · 3,375 SF

    710 S Barringer St, Florence, SC 29501
    View details

    Florence, SC Retail Properties & Spaces Investment Opportunities Market Analysis

    Explore 33 retail properties & spaces for sale in Florence, SC, showcased through 33 active listings on our real estate platform. These investment opportunities span a total of 61,449,977 square feet of properties for sale, with an estimated market value of $279,225,000.

    Sale prices for stores in Florence, SC start at $50,000, averaging $692,866, and reaching up to $13,230,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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