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Stand Alone Medical Office Building
For Sale
$1,348,000

4101 Main St Suites E & F, Hilton Head Island, SC 29926

Stand-alone medical building on Hilton Head Island, ready for occupancy.

Property Size3,600 SF
Price / SF$374.44
Days on Market260

Property Features for 4101 Main St Suites E & F

General Information

Standard status Active
Size 3,600 SF
Class A
Property subtype Medical & Office Building

Building Details

Building Size 3,600 SF
Year Built 2001
Listing Agency: NAI Carolina Chapter
Listed By: Baker Wilkins · License #31069
Source: Naiglobal
Added: Jan 27 Changed: Oct 1 Last Checked: Oct 11 at 4:38AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of NAI Carolina Chapter

Investment Insights

Based on property information with market context.

This stand-alone medical office building is located on Main Street on the north end of Hilton Head Island, just off Highway 278. The property offers convenient access to Hilton Head Hospital, the surrounding professional area, and nearby Bluffton. The ground-floor layout includes multiple exam rooms, a waiting area, and private offices. Plumbing is in place for additional exam or treatment rooms. With a size of 3600 square feet, this recently vacated building is ready for immediate tenant improvements or occupancy. It presents an ideal setting for medical or wellness users seeking a convenient and professional island location.

Key Highlights

  • Stand‑alone medical building on Hilton Head Island.
  • Prime location on Main Street, north end of Hilton Head, with easy access to Highway 278.
  • Proximity to Hilton Head Hospital and surrounding professional area.

Financial Insights

Estimated NOI and Cap Rate

NOI / Yr
$57,996
Cap Rate
4.30%
Suggested Prices Based on Cap Rates
Cap Rate 5%
$1,159,920 $1.2M
Cap Rate 7%
$828,514 $828.5K
Cap Rate 9%
$644,400 $644.4K
Market Conditions
NOI Build-Up for 3,600 SF
Gross rent
$108.0K $30.00/SF
− Vacancy
−$11.3K −$3.15/SF
EGI
$96.7K $26.85/SF
− OpEx
−$38.7K −$10.74/SF
NOI
$58.0K $16.11/SF
Area
Beaufort County, SC
Vacancy
10.50%
Lease Rate
$30.00 /SF/Yr
Expense Ratio
40.00%
Simulate Cap Rate and NOI
Suggested Prices Based on Cap Rates
Cap Rate 5%
$1,159,920
Cap Rate 7%
$828,514
Cap Rate 9%
$644,400

Alternative Uses

Best Use
Healthcare Medical
$828.5K
$725.0K – $966.6K (±1% cap)
NOI $57,996 @ 7.0% cap · market cap 4.30%
Second Best
Office B
$708.2K
$619.7K – $826.2K (±1% cap)
NOI $49,572 @ 7.0% cap · market cap 3.68%
Theoretical Best
Office A
$1.09M
$950.4K – $1.27M (±1% cap)
NOI $76,032 @ 7.0% cap · market cap 5.64%
Zoning and permitted uses should be independently verified with authorities. How Realmo checks its estimates

Property Analytics

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Current Use

Discover Specific Chiropractic Alternative Medicine Practice Tracee Spencer Hair Hair Salon Movement Mortgage Loan Service Dr. Hannah Bannon Physician Matthew Mastrorocco, DMD Dental Office

Suggested Use

Top Pick Auto Parts Store Hair Salon Big Box & Wholesale Store HVAC Service Auto Repair Shop Parking Lot & Garage

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Location Intelligence

Trade Area within ½ mile

829
Businesses Nearby
Balanced
Demand for This Use

Demographics for 29926, SC

24,832
Population
12,642
Households
2
Avg Household Size
56
Median Age
52%
College-Educated
91%
High-School Grad
28.7 sq mi
ZIP Area
865
Density / Sq Mi
$101,573
Median Household Income
$44,019
Median Earnings
$1,448
Median Rent
$600,300
Median Home Value
Check the figures for this property Cap Rate, Value Estimation, Potential NOI and more
View Realmo Analytics

Market

Vacancy Rate% for Office in South region

14.4% 2019
16.4% 2020
17.3% 2021
18% 2022
18.6% 2023
20.3% 2024
20.2% 2025
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Frequently Asked Questions

What type of property is this?
Medical Office Space - Stand-alone medical building on Hilton Head Island, ready for occupancy.
Where is this medical office space located?
The property is located at 4101 Main St Suites E & F Hilton Head Island, SC.
What is the asking price?
The asking price for this property is $1,348,000.
What are key features of this property?
This property features: Stand‑alone medical building on Hilton Head Island.; Prime location on Main Street, north end of Hilton Head, with easy access to Highway 278.; Proximity to Hilton Head Hospital and surrounding professional area.
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