Stand Alone Medical Office
For Sale
$1,348,000
4101 Main St Suites E & F, Hilton Head Island, SC 29926
Stand-alone medical building on Hilton Head Island, ready for occupancy.
Property Size3,600 SF
Price / SF$374.44
Days on Market215
Property Features for 4101 Main St Suites E & F
General Information
Standard status
Active
Size
3,600 SF
Class
A
Property subtype
Medical & Office Building
Building Details
Building Size
3,600 SF
Year Built
2001
Listing Agency:
NAI Carolina Charter
(843) 247-2470
Listed By:
Baker Wilkins · License #31069
(843) 247-2470
Source:
Naiglobal
Added: Jan 27
Changed: Aug 8
Last Checked: Aug 29 at 7:57AM
Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of NAI Carolina Charter
Investment Insights
Based on property information with market context.
This stand-alone medical office building is located on Main Street on the north end of Hilton Head Island, just off Highway 278. The property offers convenient access to Hilton Head Hospital, the surrounding professional area, and nearby Bluffton. The ground-floor layout includes multiple exam rooms, a waiting area, and private offices. Plumbing is in place for additional exam or treatment rooms. With a size of 3600 square feet, this recently vacated building is ready for immediate tenant improvements or occupancy. It presents an ideal setting for medical or wellness users seeking a convenient and professional island location.
Key Highlights
- Stand‑alone medical building on Hilton Head Island.
- Prime location on Main Street, north end of Hilton Head, with easy access to Highway 278.
- Proximity to Hilton Head Hospital and surrounding professional area.
Financial Insights
Estimated NOI and Cap Rate
NOI = area × lease_rate × (100 − vacancy) / 100 × (1 − expense_ratio). Net Operating Income — what the owner takes home each year before mortgage payments and income tax. Effective rent (asking rent minus vacancy losses) minus operating costs (taxes, insurance, maintenance, management).
NOI / Yr
$57,996
Cap rate = NOI / list price × 100. Capitalization rate — annual return on a fully cash purchase, before financing. NOI divided by price. Higher means more income per dollar invested, but usually also more risk or older condition. 5–8% is typical for stabilized commercial property; double digits often signal distressed deals.
Cap Rate
4.30%
Suggested Prices Based on Cap Rates
Cap rates vary significantly by property type, market, and asset quality.
Typical U.S. stable-market ranges:
Multifamily — 4.5% to 6.5% (Class A in primary markets often sub-5%; Class C in secondary markets 6%+)
Industrial / Logistics — 5.0% to 7.0% (compressed heavily in recent years due to e-commerce demand)
Office — 6.5% to 9%+ (wide spread post-2020; CBD Class A vs. suburban Class B varies dramatically)
Retail — 5.5% to 8.5% (grocery-anchored on the low end, unanchored strip centers higher)
Hospitality / Hotels — 7.5% to 10%+ (higher due to operational risk)
Self-Storage — 5.5% to 7.5%
Medical Office — 6.0% to 7.5%
Net Lease (single tenant, credit) — 5.0% to 7.0% depending on tenant credit and lease term
Rules of thumb:
Primary markets (NYC, SF, LA, Boston, DC) trade at lower cap rates than secondary/tertiary markets, often by 100–200 bps (bps, aka basis points; 1 bp = 0.01%).
Class A assets trade ~50–150 bps tighter than Class B, and Class B tighter than Class C.
Cap rates move inversely with price — a lower cap rate means a higher price for the same NOI.
Spread to the 10-year Treasury is a common benchmark; historically 200–400 bps over the 10-year.
Cap Rate 5%
$1,159,920
$1.2M
Cap Rate 7%
$828,514
$828.5K
Cap Rate 9%
$644,400
$644.4K
Market Conditions
NOI Build-Up for 3,600 SF
Vacancy — income lost from leasable area expected to sit empty during the year, subtracted from gross rent.
EGI (Effective Gross Income) — gross rent minus vacancy losses, the realistic income before paying operating costs.
OpEx (Operating Expenses) — recurring costs to operate the property (property tax, insurance, utilities, maintenance, management); excludes financing and capital improvements.
NOI (Net Operating Income) — income a property generates after operating costs but before financing and taxes.
Gross rent
$108.0K $30.00/SF
− Vacancy
−$11.3K −$3.15/SF
EGI
$96.7K $26.85/SF
− OpEx
−$38.7K −$10.74/SF
NOI
$58.0K $16.11/SF
Area
Beaufort County, SC
Vacancy
10.50%
Lease Rate
$30.00 /SF/Yr
Expense Ratio
40.00%
Simulate Cap Rate and NOI
Suggested Prices Based on Cap Rates
Cap rates vary significantly by property type, market, and asset quality.
Typical U.S. stable-market ranges:
Multifamily — 4.5% to 6.5% (Class A in primary markets often sub-5%; Class C in secondary markets 6%+)
Industrial / Logistics — 5.0% to 7.0% (compressed heavily in recent years due to e-commerce demand)
Office — 6.5% to 9%+ (wide spread post-2020; CBD Class A vs. suburban Class B varies dramatically)
Retail — 5.5% to 8.5% (grocery-anchored on the low end, unanchored strip centers higher)
Hospitality / Hotels — 7.5% to 10%+ (higher due to operational risk)
Self-Storage — 5.5% to 7.5%
Medical Office — 6.0% to 7.5%
Net Lease (single tenant, credit) — 5.0% to 7.0% depending on tenant credit and lease term
Rules of thumb:
Primary markets (NYC, SF, LA, Boston, DC) trade at lower cap rates than secondary/tertiary markets, often by 100–200 bps (bps, aka basis points; 1 bp = 0.01%).
Class A assets trade ~50–150 bps tighter than Class B, and Class B tighter than Class C.
Cap rates move inversely with price — a lower cap rate means a higher price for the same NOI.
Spread to the 10-year Treasury is a common benchmark; historically 200–400 bps over the 10-year.
Cap Rate 5%
$1,159,920
Cap Rate 7%
$828,514
Cap Rate 9%
$644,400
Alternative Uses
Best Use
Healthcare Medical
$828.5K
$725.0K – $966.6K
NOI $57,996 @ 7.0% cap · market cap 4.30%
Second Best
Office B
$708.2K
$619.7K – $826.2K
NOI $49,572 @ 7.0% cap · market cap 3.68%
Theoretical Best
Office A
$1.09M
$950.4K – $1.27M
NOI $76,032 @ 7.0% cap · market cap 5.64%
Zoning and permitted uses should be independently verified with authorities.
Property Analytics
Property Profile
Current Use
Location Intelligence
Trade Area within ½ mile
829
Businesses Nearby
Balanced
Demand for This Use
Explore this area
Business Placement
Demographics for 29926, SC
24,832
Population
12,642
Households
2
Avg Household Size
56
Median Age
52%
College-Educated
91%
High-School Grad
28.7 sq mi
ZIP Area
865
Density / Sq Mi
$101,573
Median Household Income
$44,019
Median Earnings
$1,448
Median Rent
$600,300
Median Home Value
Market
Vacancy Rate% for Office in South region
Questions? Ask Rey
Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.
Frequently Asked Questions
What type of property is this?
Medical Office Space - Stand-alone medical building on Hilton Head Island, ready for occupancy.
Where is this medical office space located?
The property is located at 4101 Main St Suites E & F Hilton Head Island, SC.
What is the asking price?
The asking price for this property is $1,348,000.
What are key features of this property?
This property features: Stand‑alone medical building on Hilton Head Island.; Prime location on Main Street, north end of Hilton Head, with easy access to Highway 278.; Proximity to Hilton Head Hospital and surrounding professional area.
