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Lexington County, SC Hotels for Sale

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Downtown Columbia Development Opportunity
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90,402 SF

Downtown Columbia Development Opportunity

1339 Main Street, Columbia, SC 29201

Landmark building for redevelopment in Columbia's Central Business District.

  • Landmark development opportunity in the heart of downtown Columbia.
  • Located in Columbia's Central Business District at the corner of Main Street and Washington Street.
  • Opportunity to expand development site through a partnership with the city.
  • Ideal redevelopment scenarios include hotel, mixed‑use residential/retail, or creative office/hospitality combinations.
  • Historic tax credits available.
Updated: Nov 26, 2025
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Based on your search, we've compiled 50 Potential Opportunities for your consideration. Besides 1 Active listings in Lexington County, SC, we suggest exploring several alternatives: similar 45 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Lexington Location: 4.39 Acres
$2,500,000
4.39 Acres

Prime Lexington Location: 4.39 Acres

4.39 acres in prime Lexington location, ideal for redevelopment.

210 Hendrix Street, Lexington, SC 29072
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Commercial Land Near Interstate SC
$450,000
1.42 Acres

Commercial Land Near Interstate SC

Commercial land suitable for restaurant, hotel, or retail establishment.

18330 Highway 72 East, Clinton, SC 29325
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Prime Commercial Land I-26 Exit
$450,000
1.42 Acres

Prime Commercial Land I-26 Exit

Commercial land suitable for restaurant, hotel, or retail development.

18330 Highway 72 East, Clinton, SC 29325
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Florence Commercial Lot For Sale
$1,500,000
4.02 Acres

Florence Commercial Lot For Sale

4.02 acre mixed-use lot with high visibility in Florence, SC.

1714 Second Loop Rd., Florence, SC 29501
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Explore Off-Market Properties in Lexington County, SC

Consider similar Off-Market properties in Lexington County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

2200 Airport Blvd

2200 Airport Blvd

HOTEL • 49,184 SF
Value Estimation
$3,100,000
2200 Airport Blvd, West Columbia, SC 29170-3117
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411 Piney Grv Rd

411 Piney Grv Rd

HOTEL • 27,918 SF
Value Estimation
$1,365,000
411 Piney Grv Rd, Columbia, SC 29210-3836
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2310 Charleston Hwy

2310 Charleston Hwy

HOTEL • 1,029 SF
Value Estimation by Request
2310 Charleston Hwy, Cayce, SC 29033-1708
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271 Columbiana Dr

271 Columbiana Dr

HOTEL • 37,599 SF
Value Estimation
$9,225,000
271 Columbiana Dr, Columbia, SC 29212-2277
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650 Cherokee Ln

650 Cherokee Ln

HOTEL • 48,511 SF
Value Estimation
$2,965,000
650 Cherokee Ln, West Columbia, SC 29169-3501
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2100 Bush Riv Rd

2100 Bush Riv Rd

HOTEL • 190,570 SF
Value Estimation
$765,000
2100 Bush Riv Rd, Columbia, SC 29210-5656
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1776 Burning Tree Ln

1776 Burning Tree Ln

HOTEL • 30,888 SF
Value Estimation
$4,555,000
1776 Burning Tree Ln, Columbia, SC 29210-5850
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1987 Airport Blvd

1987 Airport Blvd

HOTEL • 41,517 SF
Value Estimation
$3,900,000
1987 Airport Blvd, Cayce, SC 29033-1530
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1125 Ft Congaree Trl

1125 Ft Congaree Trl

HOTEL • 61,012 SF
Value Estimation
$12,325,000
1125 Ft Congaree Trl, West Columbia, SC 29033-3715
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1015 Lk Dr

1015 Lk Dr

HOTEL • 29,700 SF
Value Estimation
$1,975,000
1015 Lk Dr, Lexington, SC 29073-3719
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2516 Augusta Rd

2516 Augusta Rd

HOTEL • 16,200 SF
Value Estimation
$3,885,000
2516 Augusta Rd, West Columbia, SC 29169-4546
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500 Chris Dr

500 Chris Dr

HOTEL • 55,248 SF
Value Estimation
$4,430,000
500 Chris Dr, West Columbia, SC 29169-4669
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601 Columbia Ave

601 Columbia Ave

HOTEL • 38,716 SF
Value Estimation
$5,550,000
601 Columbia Ave, Lexington, SC 29072-2667
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1094 Chris Cir

1094 Chris Cir

HOTEL • 49,708 SF
Value Estimation
$6,690,000
1094 Chris Cir, West Columbia, SC 29169-4722
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211 Lanneau Ct

211 Lanneau Ct

HOTEL • 42,628 SF
Value Estimation
$8,990,000
211 Lanneau Ct, Columbia, SC 29212-2261
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328 Main St

328 Main St

HOTEL • 24,198 SF
Value Estimation
$1,365,000
328 Main St, Lexington, SC 29072-2636
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750 Saturn Pkwy

750 Saturn Pkwy

HOTEL • 48,151 SF
Value Estimation
$2,235,000
750 Saturn Pkwy, Columbia, SC 29212-2265
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2204 Airport Blvd

2204 Airport Blvd

HOTEL • 10,900 SF
Value Estimation
$585,000
2204 Airport Blvd, West Columbia, SC 29170-3117
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499 Piney Grv Rd

499 Piney Grv Rd

HOTEL • 14,112 SF
Value Estimation by Request
499 Piney Grv Rd, Columbia, SC 29210-3325
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110 Mcswain Dr

110 Mcswain Dr

HOTEL • 86,711 SF
Value Estimation
$4,310,000
110 Mcswain Dr, West Columbia, SC 29169-4804
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1107 Hbr Dr

1107 Hbr Dr

HOTEL • 15,750 SF
Value Estimation by Request
1107 Hbr Dr, West Columbia, SC 29169-3611
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4751 Sunset Blvd

4751 Sunset Blvd

HOTEL • 66,043 SF
Value Estimation
$3,380,000
4751 Sunset Blvd, Lexington, SC 29072-9151
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10 Berryhill Rd

10 Berryhill Rd

HOTEL • 34,176 SF
Value Estimation
$700,000
10 Berryhill Rd, Columbia, SC 29210-6431
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Lexington County, SC Hotels Investment Opportunities Market Analysis

Explore 46 hotels for sale in Lexington County, SC on our real estate platform. These investment opportunities span a total of 3,051,811 square feet of properties for sale, with an estimated market value of $77,380,000.

Sale prices for resorts in Lexington County, SC start at $50,000, averaging $3,684,761, and reaching up to $14,810,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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