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    Madison County, IL Medical Offices for Lease

    12 results
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    Alton Office Space for Lease
    $700 / Mo
    30,980 SF

    Alton Office Space for Lease

    307 Henry St, Alton, IL 62002

    Office space available in full-service building with parking.

    • Full‑service lease includes taxes, utilities, insurance, CAM, and light janitorial services.
    • Located in a HUB Zone.
    • Suitable for medical, legal, or other professional/personal services.
    • Building elevator provides access to all four floors.
    • Ample parking available.
    Updated: Sep 30, 2025
    View details
    Highland Medical Office Space
    $14 SF/Yr
    25,070 SF

    Highland Medical Office Space

    12603 State Route 143, Highland, IL 62249

    Prime Retail Location, Multiple Suites Available

    • 1,775 SF, 2,150 SF, and 2,604 SF of available retail space.
    • High‑traffic retail location on Highland's main thoroughfare.
    • Convenient access via signalized intersection.
    Updated: Dec 11, 2024
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    Maryville Medical Office Space
    $15 SF/Yr
    10,800 SF

    Maryville Medical Office Space

    Class B, 10,800 SF, High Visibility

    2921 Center St, Maryville, IL 62062
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    Edwardsville Office Space Available
    $9 SF/Yr
    6,249 SF

    Edwardsville Office Space Available

    Flexible Offices, Coworking & More

    101 Vandalia St, Edwardsville, IL 62025
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    Godfrey, IL Office Space
    $9 SF/Yr
    96,921 SF

    Godfrey, IL Office Space

    Multiple suites, 1,104-6,301 sq ft.

    5771 Godfrey Rd, Godfrey, IL 62035
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    Highland Medical Office Space for Sale
    $10 SF/Yr
    25,000 SF

    Highland Medical Office Space for Sale

    Prime 3,040 SF medical office, newly renovated.

    1336 Mercantile Dr, Highland, IL 62249
    View details
    Granite City Office Space Available
    $9 SF/Yr
    2,050 SF

    Granite City Office Space Available

    Office space for rent near Maryville Rd. and Pontoon Rd.

    3908 Maryville Rd, Granite City, IL 62040
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    Remodeled Medical Office Suite
    $10 SF/Yr
    3,040 SF

    Remodeled Medical Office Suite

    3,040 SF remodeled medical office suite for lease.

    1628-1336 Mercantile Dr, Highland, IL 62249
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    Medical Office Building For Lease
    $17 SF/Yr
    8,000 SF

    Medical Office Building For Lease

    Highly visible medical office building with easy highway access.

    4273 S State Route 159, Glen Carbon, IL 62034
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    Turnkey Medical Office For Lease
    $13 SF/Yr
    3,600 SF

    Turnkey Medical Office For Lease

    3,600 SF medical office with easy highway access.

    101 United Dr, Collinsville, IL
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    Collinsville Office Space for Lease
    $16 SF/Yr
    13,003 SF

    Collinsville Office Space for Lease

    13,000+ SF office space available in Collinsville's Eastport District.

    1616 Eastport Plaza Dr, Collinsville, IL 62234
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    New Office Space Available
    $18 SF/Yr
    1,855 SF

    New Office Space Available

    Newly constructed office space near St. Joseph's Hospital.

    5-25 Apex Dr, Highland, IL 62249
    View details
    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 12 Active listings in Madison County, IL, we suggest exploring alternatives. Similar 6 Properties for Sales.

    Explore Similar Spaces for Sale in Madison County, IL

    Consider Similar Space for Sale. We found 6 Spaces in Nearby Locations matching your search parameters.

    Medical Office Building For Sale
    $4,000,000
    64,800 SF

    Medical Office Building For Sale

    64,800 SF medical office building on 4.3 acres.

    1 Professional Dr, Alton, IL 62002
    View details
    Versatile Office Space in Wood River
    $399,900
    8,000 SF

    Versatile Office Space in Wood River

    8000 sq ft office space suitable for various businesses.

    203 S 6Th St, Wood River, IL 62095
    View details
    Alton Medical Campus Opportunity
    Contact for pricing
    221,754 SF

    Alton Medical Campus Opportunity

    Vacant medical campus in historic Alton, Illinois.

    915 E 5Th St, Alton, IL 62002
    View details
    Versatile Medical/Athletic Facility For Sale
    $449,000
    5,375 SF

    Versatile Medical/Athletic Facility For Sale

    5,375 SF building suitable for medical, athletic, or office use.

    1117 Washington St, Highland, IL 62249
    View details
    Renovated Medical Office Condo
    $149,000
    3,021 SF

    Renovated Medical Office Condo

    3,021 SF medical office condo for sale, renovated in 2024.

    3165 Myrtle Ave, Granite City, IL 62040
    View details
    Bethalto Office/Medical Building for Sale
    $375,000
    2,680 SF

    Bethalto Office/Medical Building for Sale

    2,680 SF office/medical building in Bethalto, Illinois for sale.

    404 W Bethalto Dr, Bethalto, IL 62010
    View details

    Madison County, IL Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in Madison County, IL with 18 listings featured on our commercial real estate exchange. The current inventory includes 8,519,813,280 square feet of properties with an estimated lease value of $140 SF/Yr.

    Estimated lease rates for Medical offices in Madison County, IL begin at $9 SF/Yr, with an average of $12 SF/Yr and extend to $18 SF/Yr.
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    Medical offices by market

    Browse Medical offices for Lease Near Madison, IL

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