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Madison County, IL Office Buildings for Sale

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Modern Office and Medical Building
Updated: Jun 25
Modern Office and Medical Building

216 Evergreen Lane, Glen Carbon, IL 62034

$1,200,000
3,990 sqft
Modern 3,990 SF commercial building (built 2018) in Magnolia Commons Business Park at 216 Evergreen Ln, Glen Carbon
2,030 SF available for lease at $22/SF NNN, with space finished in 2020
Interior features polished concrete floors, high ceilings, abundant natural light, and an open layout
Includes a private office and two ADA‑compliant restrooms
Ideal for office, medical, professional service, studio, event, or specialty retail users (verify permitted use)
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216 Evergreen Lane, Glen Carbon, IL 62034

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Medical Office Building on 4 Acres
Updated: Jan 21
Medical Office Building on 4 Acres

1 Professional Drive, Alton, IL 62002

$4,000,000
64,800 sqft 4.33 AC lot
64,800 SF medical office building on 4.3 acres with ~54,000 RSF
Over 1/2 of the building is rented; lower level and 2nd level leased under ~2–5 yr NNN leases
Two‑floor building with lower level; main floor includes lobby, bathrooms, conference room, and 2 elevators serving all levels
Brick‑and‑glass exterior with large asphalt parking area for ~270 spaces including 10 handicap spaces
Zoned C2 General Commercial Dist.; uses include medical offices, professional/personal services, retail, and restaurant
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Professional Office Building with Parking
Professional Office Building with Parking

2100 State Street, Granite City, IL 62040

$225,000
0.29 AC lot

Well-maintained office property with 36 off-street spaces and flexible space suited to service businesses in C-4.

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Multi-Use Office and Retail Building
Multi-Use Office and Retail Building

220 S Buchanan Street, Edwardsville, IL 62025

$395,000
0.22 AC lot

This versatile commercial property is designed with a welcoming foyer and a functional interior layout that can support both office and retail use.

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Warehouse with Multiple Overhead Doors
Warehouse with Multiple Overhead Doors

2726 E Broadway, Alton, IL 62002

$525,000
0.99 AC lot

Light industrial building with 8 overhead doors, plus office and garage/warehouse space.

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Full Brick Office Building
Full Brick Office Building

100 N Research Drive, Edwardsville, IL 62025

$695,000

Well-maintained full brick office building with multiple private offices, a conference room, and separate men’s and women’s restrooms.

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Brick Office Building in Business Park
Brick Office Building in Business Park

1317 D'Adrian Professional Park, Godfrey, IL 62035

$249,000
2,760 sqft 0.37 AC lot

Full brick office building with basement and extensive paved, lighted parking in a professional park setting.

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Standalone Office Building
Standalone Office Building

4 Sunset Hills Professional Center, Edwardsville, IL 62025

$750,000
3,290 sqft

Standalone office building with private offices and conference space, positioned off IL-157 in an established office/medical corridor.

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Brick Retail and Office Buildings
Brick Retail and Office Buildings

655 Berkshire Boulevard, East Alton, IL 62024

$400,000
3.30 AC lot

Two brick buildings with ample parking and overhead door offer flexible retail or office use at Berkshire Boulevard.

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Edwardsville Office Building on Campus
Edwardsville Office Building on Campus

100 N Research Drive, Edwardsville, IL 62025

$695,000
4,815 sqft

Prime commercial opportunity near SIUE campus with functional office space.

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Multi-Building Retail and Office
Multi-Building Retail and Office

655 Berkshire Boulevard, East Alton, IL 62024

$400,000
39,000 sqft

Two brick buildings totaling 39,000 square feet offer flexible retail or office use with ample parking and an overhead door.

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Office Building For Sale
Office Building For Sale

1 Horticultural Ln, Edwardsville, IL 62025

Contact for pricing
67,000 sqft

For-sale office building totaling about 67,000 square feet at 1 Horticultural Ln in Edwardsville, Illinois.

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Office/Retail Building with Leasing Potential
Office/Retail Building with Leasing Potential

7354 State Rte 162, Troy, IL

$2,300,000
4,000 sqft 1.44 AC lot

12,040 SF building with existing leases and available space.

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Troy, IL Office Park
Troy, IL Office Park

505 Buckeye Dr, Troy, IL 62294

$1,000,000
11,900 sqft

Office park with three buildings totaling 11,900 square feet.

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Alton Office Building For Sale
Alton Office Building For Sale

200 N Center Dr, Alton, IL

$795,000
27,712 sqft 2.34 AC lot

Office building with coworking space and expansion potential.

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Office Building for Sale
Office Building for Sale

3704 Pontoon Road, Granite City, IL 62040

$120,000

Office building offered for sale in Madison County, suitable for buyers seeking a commercial property for office use.

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Granite City Office Investment Property
Granite City Office Investment Property

2421 Corporate Center, Granite City, IL 62040

$1,799,000
25,000 sqft

25,000 SF office building with 93% occupancy in Granite City.

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Granite City Mixed-Use Portfolio
Granite City Mixed-Use Portfolio

2122-2132 Pontoon Road, Granite City, IL 62040

$450,000
14,336 sqft

Two-property portfolio in Granite City, Illinois, with retail and office spaces.

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Collinsville Commercial Investment Opportunity
Collinsville Commercial Investment Opportunity

2008 Vandalia St, Collinsville, IL

$220,900
3,600 sqft 1.11 AC lot

Brick building with full basement, great commercial investment opportunity.

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Single Tenant Office Building For Sale
Single Tenant Office Building For Sale

115 Executive Dr, Highland, IL

$1,950,000
12,827 sqft 3.15 AC lot

Single tenant office building with long-term lease in place.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in Madison County, IL

Madison County, IL Office Buildings Market Trends and Statistics

Explore 20 office buildings for sale in Madison County, IL, showcased through 20 active listings on our real estate platform. These investment opportunities span a total of 179,030 square feet of properties for sale, with an estimated market value of $15,408,900.

Sale prices for office properties in Madison County, IL start at $220,900, averaging $1,284,075, and reaching up to $4,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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