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    Highland, IL Medical Office Space for Lease

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    Breese, IL Troy, IL New Baden, IL
    Highland Retail/Office/Medical Spaces For Lease
    $14 SF/Yr
    1,775 SF

    Highland Retail/Office/Medical Spaces For Lease

    12603 State Rte 143, Highland, IL 62249

    Office, retail, and medical spaces available for lease in Highland.

    • Located on IL‑143 with nearly 10,000 ADT.
    • Situated at a Lighted Intersection.
    • In front of R.P. Lumber.
    • Suite 8: 2,604 SF – Office/Medical space with Waiting Area, Reception Area, Private Therapy Room, 3 Treatment Bays, Open Therapy Area, Private Office, Storage Room and Restroom.
    • Suite 6: 1,775 SF – Retail/Office space with Open Work Area, Supply Room, Private Office, Showroom, Restroom.
    Updated: Sep 22, 2025
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    Remodeled Medical Office Suite
    $10 SF/Yr
    3,040 SF

    Remodeled Medical Office Suite

    1628-1336 Mercantile Dr, Highland, IL

    3,040 SF remodeled medical office suite for lease.

    • Newly remodeled 3,040 SF medical office suite.
    • Features a staff lounge with kitchenette, waiting room with reception desk, (7) exam rooms, (1) lab/documentation area, and restrooms.
    • Strategically situated in Highland, IL, just off Highway 40 for easy access.
    • Proximity to St. Louis, MO (30 miles).
    • Well‑appointed space ideal for efficient and versatile office operations.
    Updated: Sep 19, 2023
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    Remodeled Medical Office Suite
    $10 SF/Yr
    3,040 SF

    Remodeled Medical Office Suite

    Newly remodeled medical office suite in Woodcrest Plaza, Highland, IL.

    1336 Mercantile Dr, Highland, IL 62249
    View details
    Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 3 Active listings in Highland, IL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Collinsville Office Space for Lease
    $16 SF/Yr
    13,003 SF

    Collinsville Office Space for Lease

    13,000+ SF office space available in Collinsville's Eastport District.

    1616 Eastport Plaza Dr, Collinsville, IL
    View details
    Turnkey Medical Office For Lease
    $13 SF/Yr
    3,600 SF

    Turnkey Medical Office For Lease

    3,600 SF medical office with easy highway access.

    101 United Dr, Collinsville, IL
    View details
    Medical/Professional Office Space Available
    $7 SF/Yr
    4,399 SF

    Medical/Professional Office Space Available

    Ready-to-occupy office space in St. Louis' Dogtown neighborhood.

    Saint Louis, MO
    View details
    Medical Office Suite For Rent
    $525/Mo
    1,253 SF

    Medical Office Suite For Rent

    Medical office suite featuring five exam rooms with plumbing.

    Saint Louis, MO
    View details

    Similar Spaces for Sale in Highland, IL

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Versatile Medical/Athletic Facility For Sale
    $449,000
    5,375 SF
    Versatile Medical/Athletic Facility For Sale

    5,375 SF building suitable for medical, athletic, or office use.

    1117 Washington St, Highland, IL

    View details
    New Office Space Available
    Contact for pricing
    1,855 SF
    New Office Space Available

    Newly constructed office space near St. Joseph's Hospital.

    5-25 Apex Dr, Highland, IL

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF

    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756
    View details
    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    Highland, IL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Highland, IL with 3 listings featured on our commercial real estate exchange. The current inventory includes 7,855 square feet of properties with an estimated lease value of $34 SF/Yr.

    Estimated lease rates for Medical Office Space in Highland, IL begin at $10 SF/Yr, with an average of $11 SF/Yr and extend to $14 SF/Yr.
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    Browse Medical Office Space for Lease Near Highland, IL

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    Most Searched ZIP Codes in Highland, IL

    • 62249

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