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Irvine, CA Medical Office Space for Lease

10 results
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Medical Suites in Prime Location
$3 SF/Yr
23,732 SF

Medical Suites in Prime Location

9 Corporate Park, Irvine, CA 92606

Medical suites available for lease near John Wayne Airport.

  • Prime Airport Area location
  • Medical suites for lease
  • Easy access to 405, 261 & 55 Freeways
  • Surface free parking
  • Excellent windowline
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Irvine Medical/Office Space For Lease
Contact for pricing
34,698 SF

Irvine Medical/Office Space For Lease

17305 Von Karman Ave, Irvine, CA 92614

Medical/office space in Irvine with flexible sizing and ample parking.

  • Flexible sizing options from ±1,142 to 34,698 SF to suit specific needs.
  • Ample parking for patients and staff with surface and structured options, including direct access to the 1st and 2nd floors.
  • Prime location with direct access to the 405, 55, 5, and 261 Freeways and minutes from John Wayne Airport.
  • Opportunity for doctor's customization of interior layout.
  • New, high‑quality roof installed in 2024.
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Irvine Medical Office Building
$3 SF/Yr
43,000 SF

Irvine Medical Office Building

Medical office building in Irvine with surgery center availability.

15825 Laguna Canyon Rd, Irvine, CA 92618
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Irvine Medical Office Space For Lease
$45 SF/Yr
34,698 SF

Irvine Medical Office Space For Lease

Prime Irvine medical office suites available.

17305 Von Karman Ave, Irvine, CA 92614
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Irvine Medical Office Space For Lease
$39 SF/Yr
7,005 SF

Irvine Medical Office Space For Lease

Modern Irvine medical suites, flexible space available.

9 Corporate Park, Irvine, CA 92606
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Pacifica Medical Plaza: Irvine
Contact for pricing
114,209 SF

Pacifica Medical Plaza: Irvine

Medical Office Suites Available

114 Pacifica, Irvine, CA 92618
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Prime Medical Office Suite in Irvine
Contact for pricing
4,657 SF

Prime Medical Office Suite in Irvine

4,657 SF Medical Office Space Available

13400 Jamboree Rd, Irvine, CA 92602
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Crossroads Corporate Centre, Irvine
$39 SF/Yr
58,316 SF

Crossroads Corporate Centre, Irvine

Medical Office Space Available in Irvine

3500 Barranca Pkwy, Irvine, CA 92606
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Irvine Medical Office Condo For Sale
Contact for pricing
2,477 SF

Irvine Medical Office Condo For Sale

Modern, move-in ready medical office suite.

22 Odyssey, Irvine, CA 92618
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Centerstone Plaza: Irvine Office Campus
Contact for pricing
158,000 SF

Centerstone Plaza: Irvine Office Campus

Four-building Irvine office campus, ideal for various businesses.

4000 Barranca Pkwy, Irvine, CA 92604
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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 10 Active listings in Irvine, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space in Costa Mesa
$7,024 / Mo

Medical Office Space in Costa Mesa

Professional medical/office building near Irvine, suitable for various specialties.

3151 Airway Ave, Costa Mesa, CA 92626
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Medical Office Space Available
$2 SF/Yr
1,370 SF

Medical Office Space Available

Medical office space featuring multiple exam rooms, available 1/1/2026.

3140 Red Hill Ave, Costa Mesa, CA 92626
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Medical Office Suites For Lease
Contact for pricing
23,000 SF

Medical Office Suites For Lease

Medical office suites available from 1,750 to 23,000 SF.

20071 SW Birch St, Newport Beach, CA 92660
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Newport Beach Medical Office Space
Contact for pricing
75,000 SF

Newport Beach Medical Office Space

Class A Medical Office Suites Available

3300 Irvine Ave, Newport Beach, CA 92660
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Explore Similar Spaces for Sale in Irvine, CA

Consider Similar Space for Sale. We found 7 Spaces in Nearby Locations matching your search parameters.

Corner Medical Office Clinic in Irvine
$2,968,000
63,000 SF

Corner Medical Office Clinic in Irvine

Fully built-out medical office suite in a prime location.

113 Waterworks Way, Irvine, CA 92618
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High Image Irvine Spectrum Building
$3,436,200
4,980 SF

High Image Irvine Spectrum Building

Rare 4,980 SF medical/office building in Irvine Spectrum.

108 Discovery, Irvine, CA 92618
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Freestanding Building in Irvine Spectrum
$3,735,594
5,846 SF

Freestanding Building in Irvine Spectrum

High-image building with polished concrete floors and extensive glass.

70 Discovery, Irvine, CA 92618
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Established Medical Billing Business
$675,000

Established Medical Billing Business

Profitable medical and dental billing business for sale.

2081 Buisness Ctr Dr, Irvine, CA 92612
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Dental Office Condo For Sale
$1,930,800

Dental Office Condo For Sale

Fully built-out dental office condo in Irvine Spectrum area.

113 Waterworks 260, Irvine, CA 92618
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Irvine Mixed-Use Investment Opportunity
$16,850,000
34,026 SF

Irvine Mixed-Use Investment Opportunity

Prime Irvine location, versatile space, recent renovations.

17672 Cowan, Irvine, CA 92614
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Irvine Spectrum Medical Office Building
Contact for pricing
63,430 SF

Irvine Spectrum Medical Office Building

Class B medical office building in Irvine Spectrum, built in 2008.

113 Waterworks Way, Irvine, CA 92618
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Irvine, CA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Irvine, CA with 17 listings featured on our commercial real estate exchange. The current inventory includes 7,263,673,560 square feet of properties with an estimated lease value of $130 SF/Yr.

Estimated lease rates for Medical Office Space in Irvine, CA begin at $3 SF/Yr, with an average of $26 SF/Yr and extend to $45 SF/Yr.
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