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    Orange, CA Medical Office Space for Lease

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    Two-Unit Office Building with Parking
    Updated: Dec 5, 2025
    Two-Unit Office Building with Parking

    601 E Chapman Avenue, Orange, CA 92866

    $4,500/Mo
    Two office units available separately or together
    New flooring and fresh paint in both units
    Private parking located at the rear of the building
    Signage exposure along Chapman Avenue
    Central air conditioning
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    Medical/Dental Office Space For Rent
    Updated: Apr 24
    Medical/Dental Office Space For Rent

    601 E Chapman Ave, Orange, CA 92866

    $4,500/Mo
    1,500 sqft
    Great location just 6 blocks east of the Plaza.
    Private parking in the rear of the building.
    Two units available, lease one or both.
    Great sign exposure along Chapman Ave.
    Units have new floors and fresh paint.
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    Professional Office Suites in Corporate Campus
    Professional Office Suites in Corporate Campus

    790 The City S 200, Orange, CA 92868

    $18,431/Mo

    Flexible office and medical-ready suites within a corporate campus with abundant parking and convenient freeway access.

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    Medical Office Building with Parking
    Medical Office Building with Parking

    550 & 600 S Main Street, Orange, CA 92868

    Contact for pricing
    175,000 sqft

    Lease a LEED Gold medical-ready office building with on-site parking, updated base building systems, and patient access upgrades.

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    Medical Office Condo
    Medical Office Condo

    1310 West Stewart Drive, Orange, CA 92868

    Contact for pricing
    1,968 sqft

    Medical office condo offering 1,968 rentable SF in a dedicated Orange medical corridor.

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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 5 Active listings in Orange, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space
    Medical Office Space

    13132 Newport Ave, Tustin, CA 92780

    Contact for pricing
    7,600 sqft

    7,600-square-foot medical office space offered for lease in Tustin.

    View details
    Free Standing Medical Office Building
    Free Standing Medical Office Building

    1104 W 17th St, Santa Ana, CA 92706

    Contact for pricing
    5,000 sqft

    A free standing building with medical office history and frontage on 17th St, featuring a large back lit sign.

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    Premier Medical/Professional Office Building
    Premier Medical/Professional Office Building

    1600 N Broadway, Santa Ana, CA 92701

    Contact for pricing
    107,190 sqft

    Renovated medical and professional office building with modern amenities.

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    Medical/Retail Space in Tustin
    Medical/Retail Space in Tustin

    13112 Newport Ave, Tustin, CA 92780

    Contact for pricing

    High-visibility medical/retail space in Tustin with strong demographics.

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    Similar Spaces for Sale in Orange, CA

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Entitled Medical Office Condo
    Entitled Medical Office Condo

    1122 E Lincoln, Orange, CA 92865

    $949,900
    1,192 sqft

    Remodeled medical office condo with reception lobby, common work area, and four private offices within a multi-tenant medical plaza.

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    Medical-Entitled Dental Office Condo
    Medical-Entitled Dental Office Condo

    1122 E Lincoln Unit B200, Orange, CA 92865

    $949,900
    1,192 sqft

    Remodeled in 2023, this medical-entitled dental condo includes a reception lobby, shared work area, and four private offices.

    View details
    Professional Office Building with Parking
    Professional Office Building with Parking

    2914 E Katella Avenue, Orange, CA 92867

    Contact for pricing
    8,752 sqft

    Professionally maintained office property in Orange County with reciprocal parking and prominent signage on Katella Avenue.

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    Spanish-Style Medical Office Building
    Spanish-Style Medical Office Building

    932 E Chapman Ave, Orange, CA 92866

    Contact for pricing
    4,022 sqft

    Spanish-style office building with exam and waiting rooms, historic fireplaces, and dedicated plus shared off-street parking.

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    Citrus Medical Building Opportunity
    Citrus Medical Building Opportunity

    1031 W Chapman Ave |, Orange, CA 92868

    Contact for pricing
    16 sqft

    Medical office space available in Orange, CA near hospitals.

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    Medical Office Building Suites Available
    Medical Office Building Suites Available

    1310 W Stewart Dr, Orange, CA 92868

    Contact for pricing
    1,717 sqft

    Medical suites for sale near Providence St. Joseph Hospital.

    View details

    Orange, CA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Orange, CA with 5 listings featured on our commercial real estate exchange. The current inventory includes 178,468 square feet of properties with an estimated lease value of $36.

    Estimated lease rates for Medical Office Space in Orange, CA average $36 SF/Yr.
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