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Irvine, CA

Irvine, CA Commercial Real Estate for Lease

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209 properties

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Ground-Floor Medical Office Suite

Updated: May 27

Ground-Floor Medical Office Suite

22 Odyssey, Irvine, CA 92618

$6,915/Mo

Sublease office space at 22 Odyssey, Suite 135, Irvine, CA
1,500 SF open concept suite with a professional reception/entry area
Move‑in ready suite with convenient ground‑floor access and a well‑maintained layout
Configured for pharmacy use with client‑facing operations
Central air; high‑speed internet and telecommunications readiness reported

Office Suite with Kitchen Storage

Updated: Jun 17, 2025

Office Suite with Kitchen Storage

2020 Main Street, Irvine, CA 92614

$4,593/Mo

Suite 250 includes 3 offices, a kitchen, and a storage room
Building features newly renovated five passenger elevators (400 ft/min) with 3,500 lb capacity
Freight elevator provides access to the loading dock
Parking structure includes 886 spaces, card access control, and electric vehicle charging stations
Parking garage is set to be expanded to 7 levels; first floor has a 12' ceiling

Partially Furnished Office Suite

Partially Furnished Office Suite

2020 Main Street, Irvine, CA 92614

$6,861/Mo

Suite 660 features a large open area and four glass-lined offices within a professionally managed office complex.

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Turnkey Open-Plan Medical Office

Turnkey Open-Plan Medical Office

135-22 Odyssey, Irvine, CA 92618

$6,915/Mo

1,500 sqft

Move-in ready ground-floor suite with an open workspace for client-facing medical operations and convenient parking.

Irvine Office Space For Rent

Irvine Office Space For Rent

6865 Alton Pkwy, Irvine, CA 92618

$39 SF/Yr

1,295 sqft

Single tenant office space available in Irvine, California.

Single-Story Medical Office Building

Single-Story Medical Office Building

70 Discovery, Irvine, CA 92618

Contact for pricing

5,846 sqft

Single-story freestanding office building with extensive interior and exterior glass and flexible space including lab area.

Furnished Office Suite with Parking

Furnished Office Suite with Parking

300 Spectrum Center Drive, Suite 1120, Irvine, CA 92618

Contact for pricing

8,147 sqft

Fully furnished suite in Spectrum Center with covered parking, conference space, and on-site café and gym.

Spaces Intersect

Spaces Intersect

17875 Von Karman Ave, Irvine, CA 92614

$129-$22,818/Mo

15 spaces available 11-2,001 sqft

Find fully flexible work and meeting space in Spaces Intersect. Book a tour & get info

Spaces The Quad

Spaces The Quad

530 Technology Dr, Irvine, CA 92618

$129-$24,665/Mo

15 spaces available 11-2,027 sqft

Find fully flexible work and meeting space in Spaces The Quad. Book a tour & get info

Irvine Spectrum

Irvine Spectrum

300 Spectrum Center Dr, Unit 400, Irvine, CA 92618

$119-$20,924/Mo

16 spaces available 11-2,012 sqft

Flexible workspace in Irvine Spectrum. Book a tour & get info

Irvine Center Drive

Irvine Center Drive

7545 Irvine Center Dr, Unit 200, Irvine, CA 92618

$129-$24,537/Mo

16 spaces available 11-2,042 sqft

Flexible workspace in Irvine Center Drive. Book a tour & get info

Functional Office Suite in Irvine

Functional Office Suite in Irvine

2020 Main St 1120, Irvine, CA 92614

$9,948/Mo

Well-configured office suite with modern amenities and convenient location.

Freestanding Office/Flex Building

Freestanding Office/Flex Building

15253 Bake Parkway, Irvine, CA 92618

Contact for pricing

65,006 sqft

Freestanding office/flex building with dock-high access, freight elevator service, and an on-site kitchen and cafeteria.

Irvine Concourse Office Suite

Irvine Concourse Office Suite

2020 Main St 250, Irvine, CA 92614

$4,592/Mo

Office suite with kitchen and storage in Irvine Concourse.

Irvine Office and Industrial Space

Irvine Office and Industrial Space

6400 Oak Canyon, Irvine, CA 92618

$22.20 SF/Yr

12,517 sqft

Single tenant office and industrial space available for rent.

Furnished Office Space Near Airport

Furnished Office Space Near Airport

Sky Park Circle, Irvine, CA 92614

$4,100/Mo

2,129 sqft

Move-in ready office space in Irvine, near John Wayne Airport.

Furnished Office Near John Wayne Airport

Furnished Office Near John Wayne Airport

18023 Sky Park Circle #E, Irvine, CA 92614

$4,100/Mo

2,129 sqft

Move-in ready Irvine office space with open workroom and private suites.

Ground-Floor Medical Office Suite

Ground-Floor Medical Office Suite

113 Waterworks Way, Irvine, CA 92618

Contact for pricing

1,402 sqft

Ground-floor suite with four exam rooms, storage, and two entrances for patient and private physician access.

Irvine Flex/Tech Building

Irvine Flex/Tech Building

2698 White Road (FOR SALE OR LEASE), Irvine, CA 92614

Contact for pricing

16,308 sqft

Freestanding flex/tech building in Irvine's Airport Area submarket.

Irvine Office Space For Lease

Irvine Office Space For Lease

950 Roosevelt, Irvine, CA 92620

Contact for pricing

4,960 sqft

Prime Irvine office space suitable for various professional uses.

Multi-Tenant Flex Office and Warehouse

Multi-Tenant Flex Office and Warehouse

142 Technology Dr, Irvine, CA 92618

Contact for pricing

13,830 sqft

Flex setup with office space plus warehouse, 24' clearance, and two grade-level doors, fully sprinklered.

Irvine Flex Space Available

Irvine Flex Space Available

15255 Alton Parkway, Irvine, CA 92618

Contact for pricing

5,510 sqft

Flex space with office and warehouse components for lease.

Office Space for Sublease

Office Space for Sublease

16750 Hale Ave, Irvine, CA 92606

Contact for pricing

2,016 sqft

Sublease office space available through September 30, 2028.

Irvine Office Space For Rent

Irvine Office Space For Rent

7 Corporate Park, Irvine, CA 92606

Contact for pricing

4,591 sqft

Office space available for rent in Irvine Corporate Park.

Irvine, CA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Irvine, CA with 209 listings featured on our commercial real estate exchange. The current inventory includes 97,846 square feet of properties with an estimated lease value of $823.43 /Mo.

Estimated lease rates for Commercial real estate in Irvine, CA begin at $11.72 SF/Yr, with an average of $63.34 SF/Yr and extend to $140.73 SF/Yr.

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