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    Irvine, CA Medical Office Space for Sale

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    Los Angeles, CA Lancaster, CA California City, CA
    Corner Medical Office Clinic in Irvine
    $2,968,000
    63,000 SF

    Corner Medical Office Clinic in Irvine

    113 Waterworks, Irvine, CA 92618

    Fully built-out medical office suite in a prime location.

    • Fully built‑out medical office suite, formerly a GI endoscopy center, ready for immediate use or easy reconfiguration for various medical specialties, offering significant cost savings.
    • Prime corner location within a professional medical complex providing exceptional visibility and patient accessibility.
    • Features a large procedural room designed for endoscopic or minor surgical procedures, optimizing workflow and patient care.
    • Efficient 2,157 SF layout maximizes usable space with a welcoming reception area, private offices, support areas, and dedicated clinical space.
    • Located in a well‑established medical corridor with strong co‑tenancy, convenient parking, and proximity to hospitals and major transportation routes.
    Updated: Feb 23
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    Freestanding Building in Irvine Spectrum
    $3,501,754
    5,846 SF

    Freestanding Building in Irvine Spectrum

    70 Discovery, Irvine, CA 92618

    High-image building with polished concrete floors and extensive glass.

    • Excellent location in the heart of the Irvine Spectrum, minutes from the Irvine Spectrum Retail Center and with excellent access to the 5, 405 & 133 Freeways.
    • Rare high‑image freestanding building.
    • Zoning: 5.5‑A - Medical and Science.
    • Building top signage.
    • Polished concrete floors throughout and extensive glass line on the interior and exterior.
    Updated: Nov 26, 2025
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    Office
    $8,000,000
    13,140 SF

    Office

    Medical Office Space · 13,140 SF

    15751 Rockfield Blvd, Irvine, CA 92618
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    Irvine Spectrum Medical Office Building
    $2,000,000
    63,430 SF

    Irvine Spectrum Medical Office Building

    Class B medical office building in Irvine Spectrum, built in 2008.

    113 Waterworks Way #110, Irvine, CA 92618
    View details
    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 4 Active listings in Irvine, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 5 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Building in Downtown Santa Ana
    $2,240,000
    16,320 SF

    Mixed-Use Building in Downtown Santa Ana

    High-visibility mixed-use property in downtown Santa Ana.

    503 N Main St, Santa Ana, CA 92701
    View details
    Freestanding Office/Medical Building For Sale
    $995,000
    1,614 SF

    Freestanding Office/Medical Building For Sale

    Freestanding building suitable for office or medical use.

    1902 S Standard Avenue, Santa Ana, CA 92707
    View details
    Medical Office Building For Sale
    $6,575,085
    13,283 SF

    Medical Office Building For Sale

    Medical office building with income in place and expansion potential.

    20322 SW Acacia St, Newport Beach, CA 92660
    View details
    Newport Beach Office Condo
    $1,320,000
    38,382 SF

    Newport Beach Office Condo

    Professionally built-out office condo in a desirable business submarket.

    1101 Dove Street, Suites 270 & 280, Newport Beach, CA 92660
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Murrieta Commercial Land Opportunity
    $599,900
    113,692.00 Acres

    Murrieta Commercial Land Opportunity

    Commercial land in Murrieta's Office and Research Park area.

    1 Monroe Ave & Larchmont, Murrieta, CA 92563
    View details
    Commercial Land in Temecula
    $1,249,000
    53,579.00 Acres

    Commercial Land in Temecula

    Premier commercial land in Temecula's active commercial zone.

    42079 Roick, Temecula, CA 92590
    View details
    Yucaipa Commercial Land For Sale
    $550,000

    Yucaipa Commercial Land For Sale

    Commercial land with high potential on Yucaipa Boulevard.

    31528 Yucaipa Boulevard, Yucaipa, CA 92399
    View details
    Beverly Hills Adjacent Vacant Land
    $3,475,000
    0.17 Acres

    Beverly Hills Adjacent Vacant Land

    Vacant land suitable for medical, office, and other uses.

    1044 S Robertson Blvd, Los Angeles, CA 90035
    View details

    Explore Off-Market Properties in Irvine, CA

    Consider similar Off-Market properties in Irvine, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    13400 Jamboree Rd

    13400 Jamboree Rd

    Medical Office Space
    Value Estimation by Request
    13400 Jamboree Rd, Irvine, CA 92602
    View details
    22 Odyssey Dr

    22 Odyssey Dr

    Medical Office Space • 2,477 SF
    Value Estimation by Request
    22 Odyssey Dr, Irvine, CA 92618
    View details
    22 Odyssey

    22 Odyssey

    Medical Office Space • 2,477 SF
    Value Estimation by Request
    22 Odyssey, Irvine, CA 92618
    View details
    1400 Reynolds Ave

    1400 Reynolds Ave

    Medical Office Space • 41,246 SF
    Value Estimation by Request
    1400 Reynolds Ave, Irvine, CA 92614
    View details
    16520 Bake Pkwy

    16520 Bake Pkwy

    Medical Office Space • 1,453 SF
    Value Estimation by Request
    16520 Bake Pkwy, Irvine, CA 92618
    View details

    Irvine, CA Medical Office Space Investment Opportunities Market Analysis

    Explore 9 medical office space for sale in Irvine, CA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $8,400,554.

    Sale prices for medical spaces in Irvine, CA start at $0.00, averaging $840,055, and reaching up to $3,501,754 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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