Medical Space

Rancho Santa Margarita, CA Medical Office Space for Lease

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Medical Office Space For Rent
Updated: Feb 23
Medical Office Space For Rent

29472 Avenida de las Banderas, Rancho Santa Margarita, CA 92688

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18,400 sqft
Prime location in Rancho Santa Margarita with strong visibility from Antonio Parkway.
Excellent accessibility: minutes from the 241 Toll Road and convenient access to surrounding communities.
Large patient base: Serves approximately 387,000 patients within a 15‑minute drive.
Well‑appointed 5,006 SF medical office suite (divisible to 3,000 RSF) with 14 exam rooms, procedure room, 3 private offices, and dual waiting rooms.
Under new ownership and professional management with Archer Property Partners.
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Medical Office Condo Suite
Updated: Sep 23, 2025
Medical Office Condo Suite

30212 Tomas, Rancho Santa Margarita, CA 92688

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1,620 sqft
Medical office condo suite with six offices
Includes a break room and a conference room
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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 2 Active listings in Rancho Santa Margarita, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Versatile Flex Condominium Suite
Versatile Flex Condominium Suite

100-26150 Enterprise Way, Lake Forest, CA 92630

$4,600/Mo
2,889 sqft

Flex suite sized for office, medical, showroom, training, and light industrial uses with convenient freeway access.

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Medical Building with High Visibility
Medical Building with High Visibility

23321 El Toro Rd., Lake Forest, CA 92630

Contact for pricing
9,300 sqft

Single-story medical building with ample parking and freeway access.

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Renovated Medical Office Building
Renovated Medical Office Building

24953 Paseo De Valencia Bldg C, Laguna Hills, CA 92653

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21,300 sqft

Recently renovated medical office building near Saddleback Hospital.

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Medical Office Space For Rent
Medical Office Space For Rent

24401 Calle De La Louisa, Laguna Hills, CA 92653

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40,000 sqft

New medical office space adjacent to Saddleback Memorial Hospital.

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Similar Spaces for Sale in Rancho Santa Margarita, CA

Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

Freestanding Medical Office Building For Sale
Freestanding Medical Office Building For Sale

29803 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

$3,645,600
6,076 sqft

Single-story medical office building with Santa Barbara style architecture.

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Freestanding Office Building with Patio
Freestanding Office Building with Patio

29883 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

$8,279,700

Freestanding office/medical building featuring a private patio and extensive glass with polished concrete interiors.

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Rancho Santa Margarita, CA Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Rancho Santa Margarita, CA with 2 listings featured on our commercial real estate exchange. The current inventory includes 20,020 square feet of properties.
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