Advertise
    Rancho Santa Margarita, CA
    Medical Space

    Rancho Santa Margarita, CA Medical Office Space for Lease

    Notify Me
    List
    Map
    Trabuco Canyon, CA Mission Viejo, CA Lake Forest, CA
    Medical Office Condo For Rent
    Updated: Sep 23, 2025
    Medical Office Condo For Rent

    30212 Tomas, Rancho Santa Margarita, CA

    $2 SF/Yr
    2,360 sqft · $462/Mo
    Six private offices ideal for medical practice
    Conference room for meetings and collaboration
    Reception area for patient greeting and administration
    Break room for staff convenience
    Private balcony offering a relaxing space
    View details
    Medical Office Space For Rent
    Updated: Feb 23
    Medical Office Space For Rent

    29472 Avenida de las Banderas, Rancho Santa Margarita, CA 92688

    Contact for pricing
    18,400 sqft
    Prime location in Rancho Santa Margarita with strong visibility from Antonio Parkway.
    Excellent accessibility: minutes from the 241 Toll Road and convenient access to surrounding communities.
    Large patient base: Serves approximately 387,000 patients within a 15‑minute drive.
    Well‑appointed 5,006 SF medical office suite (divisible to 3,000 RSF) with 14 exam rooms, procedure room, 3 private offices, and dual waiting rooms.
    Under new ownership and professional management with Archer Property Partners.
    View details
    Medical Office Sublease Opportunity
    Medical Office Sublease Opportunity

    22032 El Paseo, Rancho Santa Margarita, CA 92688

    Contact for pricing
    2,835 sqft

    Medical office space available for sublease in Rancho Santa Margarita.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 3 Active listings in Rancho Santa Margarita, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Versatile Flex Commercial Condominium
    Versatile Flex Commercial Condominium

    26150 Enterprise Way, Lake Forest, CA 92630

    $4,800/Mo

    Flexible flex unit suited for office, medical, showroom, training, or light industrial use with convenient freeway access.

    View details
    Medical Building with High Visibility
    Medical Building with High Visibility

    23321 El Toro Rd., Lake Forest, CA 92630

    $2 SF/Yr
    9,300 sqft · $2,092/Mo

    Single-story medical building with ample parking and freeway access.

    View details
    Medical Office Building For Lease
    Medical Office Building For Lease

    23173 La Cadena Dr, Laguna Hills, CA

    Contact for pricing
    2,858 sqft

    Freestanding medical office building featuring multiple offices and amenities.

    View details
    Medical Office Space For Rent
    Medical Office Space For Rent

    24401 Calle De La Louisa, Laguna Hills, CA 92653

    Contact for pricing
    40,000 sqft

    New medical office space adjacent to Saddleback Memorial Hospital.

    View details

    Similar Spaces for Sale in Rancho Santa Margarita, CA

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Upgraded Office Condo For Sale
    Upgraded Office Condo For Sale

    30372 Esperanza, Rancho Santa Margarita, CA 92688

    $1,585,500
    3,020 sqft

    Office condo with private offices, conference room, and break room.

    View details
    Rancho Santa Margarita Retail Unit
    Rancho Santa Margarita Retail Unit

    29851 Aventura, Rancho Santa Margarita, CA 92688

    Contact for pricing
    1,600 sqft

    1,600 SF retail unit with rear roll-up door.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land for Long-Term Lease
    Commercial Land for Long-Term Lease

    5538 E Paisano Drive, El Paso, TX 79905

    $5,950/Mo

    Lease a C4-zoned lot with easy interstate access, suited for a range of business and professional uses.

    View details
    Office Development Land For Lease
    Office Development Land For Lease

    1323 Strawfloor Drive, Jonesboro, AR 72401

    Contact for pricing
    4,000 sqft

    2.43 acres for office development with build-to-suit opportunity.

    View details
    Kingery Highway Commercial Development Opportunity
    Kingery Highway Commercial Development Opportunity

    8501 & 8511 Kingery Highway, Willowbrook, IL 60527

    $85,000 SF/Yr

    High-visibility land for retail, car wash, or medical development.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft · $32 SF/Yr

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details

    Rancho Santa Margarita, CA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Rancho Santa Margarita, CA with 3 listings featured on our commercial real estate exchange. The current inventory includes 2,360 square feet of properties with an estimated lease value of $2 SF/Yr.

    Estimated lease rates for Medical Office Space in Rancho Santa Margarita, CA begin at $2 SF/Yr, with an average of $2 SF/Yr and extend to $2 SF/Yr.
    List
    Map

    Browse Medical Office Space for Lease Near Rancho Santa Margarita, CA

    Popular Searches in Rancho Santa Margarita, CA

    Most Searched ZIP Codes in Rancho Santa Margarita, CA

    • 92688

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!