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    Costa Mesa, CA Medical Office Space for Lease

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    Los Angeles, CA San Diego, CA San Francisco, CA
    Office/Medical Space Available For Rent
    $2 SF/Yr
    5,950 SF

    Office/Medical Space Available For Rent

    1120 Bristol St, Costa Mesa, CA

    Second floor office/medical space available for rent.

    • 2nd floor location
    • Office/medical space available
    • Benefit from a #TeaserRate of $1.35 FSG for the first 6 months
    • $2.65 FSG rate thereafter
    • Available space
    Updated: Nov 10, 2025
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    Freestanding Office Building For Lease
    $2 SF/Yr
    3,350 SF

    Freestanding Office Building For Lease

    2314 Newport Blvd, Costa Mesa, CA

    Two-story office building suitable for medical or traditional office use.

    • Irreplaceable location fronting Newport Blvd.
    • Free parking in a gated/secure environment.
    • Accommodates both medical and traditional office uses.
    • High‑end interior improvements throughout.
    • Turn key possible for immediate occupancy.
    Updated: Mar 13, 2025
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    Medical Office Space Available
    Contact for pricing
    1,370 SF

    Medical Office Space Available

    Medical office space featuring multiple exam rooms, available 1/1/2026.

    3140 Red Hill Ave, Costa Mesa, CA
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    Medical Plaza in Costa Mesa
    Contact for pricing

    Medical Plaza in Costa Mesa

    Medical office space with convenient access to amenities and parking.

    1640 Newport Blvd, Costa Mesa, CA 92627
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    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 4 Active listings in Costa Mesa, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Sublease Opportunity
    $0.99 SF/Yr
    2,957 SF

    Medical Office Sublease Opportunity

    First floor physical therapist office space for sublease.

    10540 Talbert Ave, West Bldg, Fountain Valley, CA
    View details
    Newport Beach Office/Medical Space
    Contact for pricing
    31,186 SF

    Newport Beach Office/Medical Space

    Flexible office and medical spaces available for lease now.

    20162 SW Birch Street, Newport Beach, CA 92660
    View details
    Newport Irvine Medical Center Suites
    Contact for pricing
    50,000 SF

    Newport Irvine Medical Center Suites

    Class A medical office suites available for lease.

    3300 Irvine Ave, Newport Beach, CA 92660
    View details
    Fountain Valley Professional Office Suites
    Contact for pricing

    Fountain Valley Professional Office Suites

    Turn-key medical and professional office suites for lease.

    18426 Brookhurst St, Fountain Valley, CA 92708
    View details

    Explore Similar Spaces for Sale in Costa Mesa, CA

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Medical Office Building in Costa Mesa
    $7,800,000
    9,845 SF

    Medical Office Building in Costa Mesa

    NNN-leased medical office building anchored by MemorialCare.

    660 Baker Street, Building A, Costa Mesa, CA 92626
    View details
    Freestanding Retail Building in Newport Beach
    Contact for pricing
    2,340 SF

    Freestanding Retail Building in Newport Beach

    Highly visible retail building in Newport Beach with excellent frontage.

    124 E 17th St, Costa Mesa, CA 92627
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

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    0.74 acre commercial land for lease in Grand Junction.

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    Grand Junction Commercial Land Opportunity
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    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
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    El Paso Commercial Land Lease
    $3,600 /Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
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    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

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    Costa Mesa, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Costa Mesa, CA with 4 listings featured on our commercial real estate exchange. The current inventory includes 259,182,000 square feet of properties with an estimated lease value of $2 SF/Yr.

    Estimated lease rates for Medical Office Space in Costa Mesa, CA begin at $2 SF/Yr, with an average of $2 SF/Yr and extend to $2 SF/Yr.
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