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Charleston County, SC Hotels for Sale

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Four-Story Hotel with Conference Room
Updated: Oct 30, 2025
Four-Story Hotel with Conference Room

350 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464

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66,900 sqft
Holiday Inn Express & Suites is a 4‑story, 66,900 SF hotel built in 2009 with a comprehensive renovation completed in 2021
116 guest rooms
736‑SF conference room accommodates up to 40 guests
Outdoor pool and 24‑hour fitness center
109 surface parking spaces
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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 1 Active listings in Charleston County, SC, we suggest exploring several alternatives: similar 71 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Charleston Development Opportunity
Prime Charleston Development Opportunity

54 Line St, Charleston, SC 29403

Contact for pricing
0.20 AC lot

Rare 0.20-acre site in Charleston's growth corridor.

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Mount Pleasant Acreage on Hwy 41
Mount Pleasant Acreage on Hwy 41

Hwy 41, Mount Pleasant, SC 29466

$995,000
7.24 AC lot

Over 7 acres of land for sale in Mt. Pleasant.

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Prime Land I-95 Frontage
Prime Land I-95 Frontage

Us-21, Yemassee, SC 29945

$679,000
8.80 AC lot

8.8 acres zoned UD2 with I-95 visibility.

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Pooler Outparcel I-16 Visibility
Pooler Outparcel I-16 Visibility

Half Moon Lane, Pooler, GA 31322

$1,800,000
1.86 AC lot

Highly visible outparcel near I-16 and Pooler Parkway.

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Off-Market Properties in Charleston County, SC

Consider similar Off-Market properties in Charleston County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

301 Savannah Hwy
HOTEL

301 Savannah Hwy, Charleston, SC 29407-7263

$22,690,000
Estimated value
99,702 sqft 2.09 AC lot
View details
2475 Prospect Dr
HOTEL

2475 Prospect Dr, North Charleston, SC 29406-4433

$16,100,000
Estimated value
2.77 AC lot
View details
7415 Northside Dr
HOTEL

7415 Northside Dr, North Charleston, SC 29420-4209

$5,540,000
Estimated value
22,308 sqft 2.95 AC lot
View details
200 King St
HOTEL

200 King St, Charleston, SC 29401-3109

$1,895,000
Estimated value
2,782 sqft 0.06 AC lot
View details
1596 Palmetto Grande Dr
HOTEL

1596 Palmetto Grande Dr, Mount Pleasant, SC 29464

$17,930,000
Estimated value
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78 Queen St, Unit 302
HOTEL

78 Queen St, Charleston, SC 29401-2220

Unit 302
Value Estimation by Request
219 sqft 0.01 AC lot
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112 Market St
HOTEL

112 Market St, Charleston, SC 29401-3157

$15,375,000
Estimated value
9,512 sqft 0.33 AC lot
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110 Market St
HOTEL

110 Market St, Charleston, SC 29401

$12,845,000
Estimated value
7,945 sqft 0.49 AC lot
View details
39 Hayne St
HOTEL

39 Hayne St, Charleston, SC 29401-3105

Value Estimation by Request
0.04 AC lot
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78 Queen St, Unit 202
HOTEL

78 Queen St, Charleston, SC 29401-2220

Unit 202
Value Estimation by Request
252 sqft
View details
261 Magrath Darby Blvd
HOTEL

261 Magrath Darby Blvd, Mount Pleasant, SC 29464

$13,710,000
Estimated value
15,069 sqft 2.56 AC lot
View details
1943 Savannah Hwy
HOTEL

1943 Savannah Hwy, Charleston, SC 29407-6250

$7,900,000
Estimated value
12,788 sqft 1.99 AC lot
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570 King St
HOTEL

570 King St, Charleston, SC 29403-4833

Value Estimation by Request
24,320 sqft 1.31 AC lot
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17 Orange St
HOTEL

17 Orange St, Charleston, SC 29401

$1,130,000
Estimated value
700 sqft 0.18 AC lot
View details
78 Queen St, Unit 103
HOTEL

78 Queen St, Charleston, SC 29401-2220

Unit 103
Value Estimation by Request
251 sqft
View details
2058 Savannah Hwy
HOTEL

2058 Savannah Hwy, Charleston, SC 29407-6287

$3,855,000
Estimated value
15,198 sqft 1.84 AC lot
View details
475 Bay St
HOTEL

475 Bay St, Charleston, SC 29403-6336

Value Estimation by Request
6,700 sqft 1.97 AC lot
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2415 Mall Dr
HOTEL

2415 Mall Dr, North Charleston, SC 29406-6516

$13,130,000
Estimated value
72,260 sqft 2.50 AC lot
View details
332 King St
HOTEL

332 King St, Charleston, SC 29401-1440

$9,500,000
Estimated value
12,388 sqft 0.23 AC lot
View details
7480 Northwoods Blvd
HOTEL

7480 Northwoods Blvd, North Charleston, SC 29406-4025

$7,480,000
Estimated value
17,248 sqft 2.48 AC lot
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7641 Northwoods Blvd
HOTEL

7641 Northwoods Blvd, North Charleston, SC 29406-4033

$4,575,000
Estimated value
38,904 sqft 1.57 AC lot
View details
2070 Mcmillan Ave
HOTEL

2070 Mcmillan Ave, North Charleston, SC 29405-7774

$5,880,000
Estimated value
36,148 sqft 1.68 AC lot
View details
2600 Elms Ctr Rd
HOTEL

2600 Elms Ctr Rd, North Charleston, SC 29406-9327

$8,855,000
Estimated value
42,882 sqft 2.19 AC lot
View details

Charleston County, SC Hotels Market Trends and Statistics

Explore 72 hotels for sale in Charleston County, SC on our real estate platform. These investment opportunities span a total of 66,900 square feet of properties for sale.

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