Charleston County, SC Commercial Real Estate for Lease

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368 properties
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Renovated Flex Space with Open Layout
Renovated Flex Space with Open Layout

2467 Savannah Hwy, Charleston, SC 29414

$1,900/Mo
3,704 sqft

Open-plan suites include bathrooms and a break area.

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Single-Story Office Building
Single-Story Office Building

255 East Bay Street, Charleston, SC 29401

$35 SF/Yr
4,730 sqft

Centrally located office building with flexible lease terms and included parking to support medical or professional users.

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Downtown Daniel Island Office Suites
Downtown Daniel Island Office Suites

895 Island Park Drive, Charleston, SC 29492

$33 SF/Yr
2,713 sqft

Office suites with adaptable layouts, including private offices, conference rooms, breakrooms, and restrooms.

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Dorchester Road Office Space Available
Dorchester Road Office Space Available

7880 Dorchester Rd, North Charleston, SC 29418

$16 SF/Yr
6,600 sqft

High-traffic location with flexible spaces for professional use.

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Downtown Office Suite with Conference Room
Downtown Office Suite with Conference Room

170 Meeting Street, Charleston, SC 29401

$45 SF/Yr
4,310 sqft

First-floor suite offers open space, private offices, kitchen area, and a conference room in a 5-story building.

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Class A Flex Space Available
Class A Flex Space Available

547 Long Point Road, Mount Pleasant, SC 29464

$20 SF/Yr
4,380 sqft

Flex space with showroom/office and warehouse, convenient location.

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Prime Retail Space Near Tanger
Prime Retail Space Near Tanger

4952 Centre Pointe Dr, North Charleston, SC 29418

$16 SF/Yr
11,074 sqft

11,074 SF retail space in Charleston's largest retail hub.

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Class A Ground-Floor Office Space
Class A Ground-Floor Office Space

134 Meeting Street, Charleston, SC 29401

$44 SF/Yr
15,254 sqft

Lease approximately 4,988 SF on the first floor with abundant windows, open space, and wraparound views.

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Warehouse with Drive-Through Access
Warehouse with Drive-Through Access

3319-3320 Biedler Street, North Charleston, SC 29418

$17.50 SF/Yr
7,800 sqft

Renovations are underway, with planned office improvements and a partially enclosed outdoor area.

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Renovated Class A Office Building
Renovated Class A Office Building

4055 Faber Place Drive, North Charleston, SC 29405

$30 SF/Yr
1,947 sqft

Three-story office building with high-end finishes, available April 2026.

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Class A Medical Office Building
Class A Medical Office Building

1200 Innovation Way, Mount Pleasant, SC 29466

$28 SF/Yr
14,084 sqft

Renovated medical/office building with ample parking in Mt. Pleasant.

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Recreational Facility with Squash Courts
Recreational Facility with Squash Courts

1437 King Street Extension, Charleston, SC 29405

$25 SF/Yr
6,000 sqft

Former squash club offers three courts, locker rooms, showers, sauna, and heated/cooled space suitable for recreation concepts.

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Flex Office Suites in Business Center
Flex Office Suites in Business Center

1941 Savage Rd, Charleston, SC 29407

$1,200/Mo
2,080 sqft

Five flex-office suites are available with immediate occupancy, including options to combine for larger space needs.

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Class A Office Space Available
Class A Office Space Available

4401 Leeds Avenue, North Charleston, SC 29405

$34.50 SF/Yr
8,452 sqft

Four-story, 102,024 SF Class A office building for lease.

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Industrial Warehouse Office Suite
Industrial Warehouse Office Suite

7148 Cross County Road, North Charleston, SC 29418

$15 SF/Yr
2,014 sqft

Industrial warehouse suite with dedicated office area and a drive-in door, available immediately.

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Class A Office Space
Class A Office Space

100 Calhoun Street, Charleston, SC 29401

$43 SF/Yr
9,675 sqft

Multi-tenant office building in Charleston's Historic District.

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Industrial Complex with Flexible Units
Industrial Complex with Flexible Units

4509 Savannah Highway, Ravenel, SC 29470

$14.50 SF/Yr
4,533 sqft

Multi-building industrial complex with modern construction and efficient layouts.

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Renovated Flex Space Suite
Renovated Flex Space Suite

2140 Beaufort Avenue, North Charleston, SC 29405

$15 SF/Yr
2,365 sqft

Recently renovated commercial suite with updated parking, lighting, office, and restroom improvements.

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Multi-Suite Light Industrial Facility
Multi-Suite Light Industrial Facility

7167 Cross County Rd, North Charleston, SC 29418

$11,220/Mo
15,128 sqft

Well-maintained flex-style suites suited for light industrial, warehouse, distribution, or manufacturing use.

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Historic Office Suite with Rooftop Patio
Historic Office Suite with Rooftop Patio

81 Hasell Street, Charleston, SC 29401

$2,300/Mo

Character-rich workspace with an open plan, original architectural details, and shared outdoor amenity access.

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Park Circle Freestanding Retail Building
Park Circle Freestanding Retail Building

1086 East Montague Avenue, North Charleston, SC 29405

$35 SF/Yr
1,800 sqft

Freestanding building in Park Circle, ideal for retail or office.

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King Street Retail Space Available
King Street Retail Space Available

677 King Street, Charleston, SC 29403

$60 SF/Yr
1,920 sqft

New retail space with patio on King Street.

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Upper King Street Office Space
Upper King Street Office Space

463 King Street, Charleston, SC 29403

$34 SF/Yr
3,204 sqft

Office space for rent in Charleston's Upper King District.

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Furnished Office Building Sublease Opportunity
Furnished Office Building Sublease Opportunity

125 Fairchild Street, Charleston, SC, USA, Charleston, SC 29492

$24 SF/Yr
78,394 sqft

Well-appointed, fully furnished office building available for sublease.

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