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    South Carolina Commercial Real Estate for Lease

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    3,260 properties
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    Mixed-Use Retail and Office Space
    Mixed-Use Retail and Office Space

    2295 Hoffmeyer Rd, Florence, SC 29501

    Contact for pricing
    7,465 sqft

    7,465-square-foot property within a redevelopment featuring retail, office, medical, dining, and lifestyle spaces.

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    Hospital-Anchored Medical Office Building
    Hospital-Anchored Medical Office Building

    986 Wellness Way, Fort Mill, SC 29715

    Contact for pricing
    1,831 sqft

    Three-story medical outpatient building with an enclosed walkway connection to Fort Mill Hospital–Piedmont Medical Center.

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    Secure Self-Storage Property
    Secure Self-Storage Property

    83 Rocky Slope Rd, Greenville, SC 29607

    $1,500/Mo
    1,200 sqft

    Fully fenced yard with three covered storage buildings, additional uncovered storage, and on-site electricity.

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    Retail Unit with Drive-Thru Capability
    Retail Unit with Drive-Thru Capability

    1650 Church Street, Conway, SC 29526

    Contact for pricing
    2,353 sqft

    Open floor plan retail unit with co-tenants McAlister's and SGA Dental and signalized corner visibility.

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    King Street Retail Space Available
    King Street Retail Space Available

    423 King Street, Charleston, SC 29403

    Contact for pricing
    3,162 sqft

    Prime retail space in Charleston's bustling King Street shopping district.

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    Elgin Office Space Available
    Elgin Office Space Available

    565 Spears Creek Church Rd, Elgin, SC 29045

    Contact for pricing
    146,483 sqft

    Office space available for lease in Elgin, South Carolina.

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    Restaurant Space with Major Frontage
    Restaurant Space with Major Frontage

    5420 Forest Dr, Columbia, SC 29206

    Contact for pricing
    12,000 sqft

    Second-generation restaurant space available with excellent Forest Drive visibility and strong nearby interstate traffic.

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    Medical Office Suite with Studio Room
    Medical Office Suite with Studio Room

    102 Buford Avenue, Anderson, SC 29621

    Contact for pricing
    2,000 sqft

    Well-maintained medical/office suite includes multiple private offices and a large mirrored studio room for flexible use.

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    Office Space Overlooking Falls Park
    Office Space Overlooking Falls Park

    320 Falls Street, Greenville, SC 29601

    Contact for pricing
    25,154 sqft

    Office space for rent in downtown Greenville near Peace Center.

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    Retail Space Under Renovation
    Retail Space Under Renovation

    North Myrtle Beach, SC 29582

    Contact for pricing
    5,000 sqft

    Retail space available for rent, delivery expected in 2026.

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    Retail Endcap with Patio
    Retail Endcap with Patio

    739 Galleria Blvd, Rock Hill, SC 29730

    Contact for pricing
    1,200 sqft

    Available 2,400 SF endcap includes a patio and is accessible from both Galleria Blvd and Old Springdale Rd.

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    Flex Office-Warehouse Space
    Flex Office-Warehouse Space

    471 Lakeshore Parkway, Rock Hill, SC 29730

    Contact for pricing
    28,188 sqft

    Flex space offers office and warehouse options within a PUD-zoned TechPark location near I-77.

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    Three-Story Office Building
    Three-Story Office Building

    186 Dunbarton Drive, Florence, SC 29501

    Contact for pricing
    32,087 sqft

    Three-story office building offering private offices, open workspace, and a ground-floor café-style break room.

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    Historic Office Space with Tall Ceilings
    Historic Office Space with Tall Ceilings

    14 S Main St, Greenville, SC 29601

    Contact for pricing
    1,117 sqft

    Historic office units feature tall ceilings, a warm open layout, and an on-site property manager.

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    Turn-Key Medical Office Suite
    Turn-Key Medical Office Suite

    14 OAK FOREST RD, Bluffton, SC 29910

    Contact for pricing
    950 sqft

    Turn-key medical office suite with a waiting area, three exam rooms, private restroom, and kitchenette, ready for immediate occupancy.

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    Office Suite with Storage
    Office Suite with Storage

    386 Spanish Wells Rd, Hilton Head Island, SC 29926

    Contact for pricing
    2,175 sqft

    High-end finished office space includes extra storage and rear-access double doors with ample parking.

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    Industrial Space Near GSP Airport
    Industrial Space Near GSP Airport

    111 Apple Valley Rd, Duncan, SC 29334

    Contact for pricing
    224,640 sqft

    Industrial space for lease near major transportation routes and businesses.

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    Retail Space Near Ravenel Bridge
    Retail Space Near Ravenel Bridge

    855 Houston Northcutt Blvd, Mount Pleasant, SC 29464

    Contact for pricing
    863 sqft

    Retail space in Whole Foods anchored shopping center available for lease.

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    Industrial Building Near Amazon Center
    Industrial Building Near Amazon Center

    14 Lake Dr, Inman, SC 29349

    Contact for pricing
    5,260 sqft

    Industrial building for lease near major distribution hub.

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    Industrial Warehouse Distribution Facility
    Industrial Warehouse Distribution Facility

    3961 Wesley Street, Myrtle Beach, SC 29579

    Contact for pricing
    25,170 sqft

    Two-building industrial property with fenced, gated laydown areas and multiple grade-level roll-up doors.

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    Medical Office on Oakland Avenue
    Medical Office on Oakland Avenue

    356 Oakland Avenue, Rock Hill, SC 29732

    Contact for pricing
    3,600 sqft

    3,600 SF medical office space for lease in Rock Hill.

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    Office Space Near Major Retailers
    Office Space Near Major Retailers

    248 Latitude Ln, Lake Wylie, SC 29710

    Contact for pricing
    3,850 sqft

    Office space available for rent near national retailers including Walmart and Publix.

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    Industrial Warehouse Sublease
    Industrial Warehouse Sublease

    160 National Ave, Spartanburg, SC 29303

    Contact for pricing
    103,103 sqft

    Industrial warehouse space is available for sublease at 160 National Ave in Spartanburg.

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    West Columbia Office Space Available
    West Columbia Office Space Available

    3634 Sunset Blvd., West Columbia, SC 29169

    Contact for pricing
    7,200 sqft

    Office space for lease near Lexington Medical Center corridor.

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